• Journal of Integrative Natural Science
• /
• v.11 no.2
• /
• pp.121-129
• /
• 2018

CXCR6 is a major target in drug design as it is a determinant receptor in many diseases like AIDS, Type I Diabetes, some cancer types, atherosclerosis, tumor formation, liver disease and steatohepatitis. In this study, we propose the active site residues of CXCR6 molecule. We employed homology modelling and molecular docking approach to generate the 3D structure for CXCR6 and to explore its interaction between the antagonists and agonists. 3D models were generated using 14 different templates having high sequence identity with CXCR6. Surflex docking studies using pyridine and pyrimidine derivatives enabled the analysis of the binding site and finding of the important residues involved in binding. 3D structure of CXCL16, a natural ligand for CXCR6, was modelled using PHYRE and protein - protein docking was performed using ClusPro. The residues which were found to be crucial in interaction with the ligand are THR110, PHE113, TYR114, GLN160, GLN195, CYS251 and SER255. This study can be used as a guide for therapeutic studies of human CXCR6.

• Journal of the Korean Society of Clothing and Textiles
• /
• v.19 no.3
• /
• pp.525-535
• /
• 1995

This study was designed to verify the clothing satisfaction according to product type (jacket vs. pantyhose) and consumer fashion involvement. Research problems were as following; 1. To identify a clothing satisfaction according to product type. 2. To discover which of satisfaction relevant variables has the most influence on clothing satisfaction. 3. To examine the relationship between expectations and discontinuations. 4. To examine the degree of influence of product type and consumer fashion involvement on expectations. The survey was carried out in Pulsar shopping area. The 104 subjects (51 for jacket, 53 for pantyhose) participated in the final analysis. The results of analysis were as following; 1. The main path of clothing satisfaction was that the product type -1 the expectations -1 the perceived performance (-1 the discontinuation) -1 the clothing satisfaction. Those relevant variables explained 62% of clothing satisfaction variance. The most powerful determinant was the perceived performance. 2. For jacket type, the influence of perceived performance appeared to be greater than that of the discontinuation. And the consumer fashion involvement affected the expectations and the discontinuation. 3. For pantyhose type, the consumer fashion involvement divan't affect the expectations. The influence of discontinuation was relatively higher than that of jacket type.

• Culinary science and hospitality research
• /
• v.13 no.3
• /
• pp.220-238
• /
• 2007

This study investigates the importance of customers who use hotel restaurants on the basis of literature and actual data, establishes positioning strategies to stimulate hotel restaurants amidst an intensely competitive market, and sets up marketing strategies that can be applied to hotel restaurant business from the analysis results. Determinant factors for hotel restaurants were service quality, food, atmosphere and cleanness, brand and reputation, the attitude and appearance of attendants, and variety of menu, in the order of importance. As for the analysis results for satisfaction, the higher the customers regarded on the attitude and appearance of attendants and the food of the restaurant, the higher the overall satisfaction, the intention of revisiting, and the intention of recommendation of the customers became. Therefore, the marketing and promotion staffs of hotel restaurants should search for the ways to meet these needs of customers as much as possible, and identify the usage inclinations and satisfaction level of customers when carrying out marketing activities and establishing customer relationship marketing strategies.

• The Journal of Asian Finance, Economics and Business
• /
• v.7 no.9
• /
• pp.427-438
• /
• 2020

This study aims to analyze and confirm brand awareness' role in influencing the repurchase intention both directly and indirectly on customer satisfaction variables and repurchase intention variables. The contribution brought by this study is to reflect manifest variables such as recall, purchase, and consumption. The number of respondents in this study was 200 samples using the online survey data collection method (Google form), while the research approach is quantitative explanatory. The data analysis test tools include the Structural Equation Modeling (SEM) approach with AMOS as a statistical data analysis software and Sobel test to indirectly test the relationship. This study consists of four hypotheses, of which three hypotheses are positively and significantly related (brand awareness on repurchase intention, brand awareness on customer satisfaction, and customer satisfaction on repurchase intention). Through indirect relationship, namely, brand awareness on repurchase intention through customer satisfaction, the study showed no significant effect. In a comprehensive way, this study emphasizes the factor of customer satisfaction as a determinant of consumer loyalty and repurchase intention. Therefore, creating optimal customer satisfaction, service excellence, promotion and massive advertising, guaranteeing the safety and ease-of-use apps, and ease of shopping, especially for e-commerce industry, is a serious concern.

• Journal of the Korean Society of Clothing and Textiles
• /
• v.34 no.5
• /
• pp.765-774
• /
• 2010

This study investigates the effects of consumer innovativeness on e-loyalty mediated by shopping mall attributes and consumer satisfaction with the Internet. Data were obtained from 243 consumers who had bought fashion products through online shopping. Data were analyzed by using factor analysis, Cronbach's alpha, and path analysis using LISREL 8.53 program. The results of this study suggest that the consumer innovativeness, such as Internet-innovativeness and Fashion-innovativeness affect shopping mall attributes including Loading, Visual, Information, Variety, and Price/Fashion. These attributes and the shopping mall satisfaction partially mediated the impact of consumer innovativeness on e-loyalty of shopping malls through the Internet. Especially, consumer satisfaction was the most important determinant to build up e-loyalty for the online shopping of fashion products. The findings provide implications for e-retailers to develop strategies related to consumer innovativeness, shopping mall attributes, and the e-loyalty of shopping malls for fashion products.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
• /
• 2002.05a
• /
• pp.166-174
• /
• 2002

This paper presents an analytical method to Investigate the stability of a hydrodynamic journal bearing with rotating herringbone grooves. The dynamic coefficients of the hydrodynamic journal bearing are calculated using the FEM and the perturbation method. The linear equations of motion can be represented as a parametrically excited system because the dynamic coefficients have time-varying components due to the rotating grooves, even in the steady state. Their solution can be assumed as a Fourier series expansion so that the equations of motion can be rewritten as simultaneous algebraic equations with respect to the Fourier coefficients. Then, stability can be determined by solving Hill's infinite determinant of these algebraic equations. The validity of this research is proved by the comparison of the stability chart with the time response of the whirl radius obtained from the equations of motion. This research shows that the instability of the hydrodynamic journal bearing with rotating herringbone grooves increases with increasing eccentricity and with decreasing groove number, which play the major roles in increasing the average and variation of stiffness coefficients, respectively. It also shows that a high rotational speed is another source of instability by increasing the stiffness coefficients without changing the damping coefficients.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
• /
• 2002.05a
• /
• pp.181-189
• /
• 2002

This research presents an analytical model to investigate the stability due to the ball bearing waviness in a rotating system supported by two ball bearings. The stiffness of a ball bearing changes periodically due to the waviness in the rolling elements as the rotor rotates, and it can be calculated by differentiating the nonlinear contact forces. The linearized equations of motion can be represented as a parametrically excited system in the form of Mathieu's equation, because the stiffness coefficients have time-varying components due to the waviness. Their solution can be assumed as a Fourier series expansion so that the equations of motion can be rewritten as the simultaneous algebraic equations with respect to the Fourier coefficients. Then, stability can be determined by solving the Hill's infinite determinant of these algebraic equations. The validity of this research is proved by comparing the stability chart with the time responses of the vibration model suggested by prior researches. This research shows that the waviness in the rolling elements of a ball bearing generates the time-varying component of the stiffness coefficient, whose frequency is called the frequency of the parametric excitation. It also shows that the instability takes place from the positions in which the ratio of the natural frequency to the frequency of the parametric excitation corresponds to i/2 (i= 1,2,3..).

• Journal of Technology Innovation
• /
• v.4 no.1
• /
• pp.1-26
• /
• 1996

Traditional studies of new venture performance have focused on the characteristics of entrepreneurs and have shown conflicting results on the relationship between the characteristics and performance of new ventures. Recently, some researchers have broadened their search to include aspects of the industry and the strategy of new ventures. The purposes of this study are to identify wtrategic archetypes of new ventures based on the taxonomic approach and to explain the differences in new venture characteristics and performance among strategic archetypes. To find the strategic archetypes, 114 new venture CEOs from various industries were asked to describe their ventures' competitive strategy through 19 questionnaire items on competitive methods. Using factor analysis and subsequent cluster analysis, four archetypes were identified such as : versatile type, technology-driven type, market-oriented type, and cost reduction type. The results imply that there exist different types of venture strategy even among new technology-based venture firms in Korea, and show the differences in performance among strategic archetypes: market-oriented type and versatile type are better than cost reduction type in terms of growth rate and profitability. Because the venture strategy in identified as a major determinant of the venture performance in this study, the choice of venture strategy suitable for firm's industrial characteristics and internal resource bases becomes a very strategic decision for firm's sustained growth. Further studies are needed to strengthen some methodological limitations of the study.

• The Journal of Asian Finance, Economics and Business
• /
• v.7 no.8
• /
• pp.705-714
• /
• 2020

This study aims to investigate the main factors that affected the government health expenditures in Gulf Cooperation Council (GCC) countries (Kingdom of Saudi Arabia (KSA), United Arab Emirates (UAE), Oman, Qatar, Bahrain and Kuwait), during the period from 2005 to 2019. The study employs a panel data technique in order to monitor the pooled determinant variables of healthcare expenditures in these countries. The study's results indicate, by using FMOLS approach for panel data, that the average healthcare expenditures per capita in GCC countries have a positive and a significant relationship with the government revenues, the size of the population, and the governments' public debt. The positive and the significant relationships of governments' public debt may be explained even if the governments of the GCC countries suffer from a budget deficit; the GCC countries continue to increase the healthcare expenditure. The study suggests that the policymakers of the GCC countries must take into consideration those variables when they develop their healthcare policies. Also, the GCC countries urgently need to have high levels of foreign exchange reserves to maintain the expected level of spending on the healthcare sector, because their public revenues depend mainly on the oil revenues, which are fluctuating continuously.

• The Journal of Asian Finance, Economics and Business
• /
• v.7 no.10
• /
• pp.981-988
• /
• 2020

Seeing the existence of MSME needs that have still not been met although this sector is undeniably important in Indonesian economy, changes in community behaviour and the intensity of the use of technology in the community, financial technology (fintech) has a lot of potentials to become a part of the solution of the problem commonly faced by MSMEs. Therefore this research needs to be done to observe the potential of fintech in integrating MSMEs in terms of the application of technology and knowledge from the community related to fintech. By using Technology Acceptance Model, this research tries to understand the determinant factors of the fintech application used by MSME. Based on the research framework and model, path analysis method used in this research. This research uses primary data gathered by the questioner, which was distributed to MSME. From the analysis conducted, we can conclude that the external factors tested in this research could have an effect on the behaviour intention through perceived usefulness in MSME practice of financial technology. Large variation in MSME educational background, busineess age and size would become a challenge in promoting fintech application, therefore this finding suggests that fintech should be promoted by highlighting what benefits can be obtained by using fintech application.