• The Korean Journal of Physiology and Pharmacology
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• v.17 no.5
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• pp.441-446
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• 2013

In the present study, the anti-depressant like effect of methyl gallate (MG) isolated from the stem bark of Acer barbinerve was examined in ICR mice. Body weight (BDW) and blood glucose (BDG) levels significantly decreased in the repeated restraint stress (RRS) group (2 h/day for 14 days) compared to the no stress (NS) group. To examine the effect of MG on RS-induced BDW loss and hypoglycemia, MG (10 mg/kg) and the anti-depressant fluoxetine (10 mg/kg) were administered daily for 14 days. Orally administered MG and fluoxetine significantly attenuated the RS-induced BDW loss and hypoglycemia. Interestingly, MG administered mice showed increased BDG levels in the normal and glucose feeding condition. Chronic RS-subjected mice showed immobilized and depressed behaviors. The effect of MG on the depressed behaviors was evaluated using the tail-suspension test (TST) and the forced swimming test (FST). In both tests, RS-induced immobilized behaviors were significantly reversed in MG and fluoxetine administered groups. Taken together, MG significantly attenuated the RS-induced BDW loss, hypoglycemia, and depressed behaviors. Considering that decreased BDG levels (hypoglycemia) can cause depression, MG may exert its anti-depressant like effect by preventing hypoglycemia. Our results suggest that MG isolated from A. barbinerve can exert anti-depressant like effect, and could be used as a new and natural anti-depressant therapy.

• Science of Emotion and Sensibility
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• v.20 no.1
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• pp.83-94
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• 2017

In this study, we figured out that music modes and item types could affect people's urged decision making through a k-value which results from a delay discounting's hyperbolic function. Generally, high k-value is related to impulsive decision making. Concretely, there was a significant interaction between items and music. For the luxury item, the k-value was higher while listening to major music than minor. However, for the non-luxury item condition the k-value difference was not significant between two pieces of music. Moreover, we expected mood could be manipulated after listening to the music and mediate a difference of tendency. We used first movement as an allegro and second as an andante of Mozart piano concerto No.5 D-major and No.20 D-minor for stimuli. As a result, mode and tempo's main effects were not significant. Nevertheless, there was a significant two-way interaction. To put it concretely, the k-value of major condition was marginally higher than minor condition on allegro. However, the k-value of major condition was significantly lower than minor condition on andante. Also, depressed degree difference was significant but it was not significant as a mediator. Set depressed degree as a predict variable and future time span as a mediator, further research found future time perception partially mediated the effect that depressed degree affects impulsivity.

• Journal of Oriental Neuropsychiatry
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• v.16 no.2
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• pp.233-242
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• 2005

'Ul-zeong' comes from obsturction of qi by stress. The mind affect the body. The patient has depressed mood, irritable sign, chest discomfort, costral pain, angry state or some strange feeling on the throat. $'Y{\acute{i}}q{\acute{i}}ngbi{\grave{a}}nq{\grave{i}}'$ is a psychological therapy that a doctor changes the patient ' s psychological condition by using various method. 'yi' means moving, 'qing' means changing. Art therapy means a therapy by using artistic activities and included in $'y{\acute{i}}q{\acute{i}}ngbi{\grave{a}}nq{\grave{i}}'$ In this case, a female patient, 35 years old, who suffered from 'ul-zeong' with depressed mood, anxiety, general body weakness, anorexia, constipation. We used $'y{\acute{i}}q{\acute{i}}ngbi{\grave{a}}nq{\grave{i}}'$ besides herbal medication, acupuncture to her and her condition got improved. Therefore we reported it for the treatment.

• Journal of Nutrition and Health
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• v.47 no.2
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• pp.113-123
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• 2014

Purpose: Vitamin D has been known to play an important role in the central nervous system and brain functions in the human body, and cumulative evidence has shown that vitamin D deficiency might be linked with various mental health conditions. Epidemiologic studies have shown that vitamin D deficiency may be associated with higher risk of depression in the US and European populations. However, limited information is available regarding the association between vitamin D status and depression in the Korean population. The objective of this study was to examine the associations between vitamin D levels and prevalence of depression. Methods: We conducted a cross-sectional analysis using nationally representative data from the 2008-2010 Korean National Health and Nutrition Examination Survey from which serum 25-hydroxyvitamin D concentrations were available. A total of 18,735 adults who had available demographic, dietary, and lifestyle information were included in our analysis. We defined "depression" with a diagnosis by a physician. "Depressed condition" was defined as having feelings of sadness or depression without diagnosis by a physician. Results: The prevalence of depression was 1.63% and 5.43% in Korean men and women, respectively; 12.5% of men and 26.1% of women were defined as the group having depressed conditions. In multivariate logistic regression models, no significant associations were observed between vitamin D status and prevalence of depression or depressed conditions in Korean men and women. Conclusion: We found no association between vitamin D insufficiency and depression/depressed conditions in Korean adults. Future large prospective studies and randomized controlled trials are needed to confirm this relationship.

• Journal of Acupuncture Research
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• v.15 no.2
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• pp.157-171
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• 1998

In order to study the effect of direct moxibustion on depressed immune response and thyroid hormone in rats exposed to cold stress, Sprague-Dawley male rats were put in the horizontal refrigerator by $-10^{\circ}C$ for 14 days and thereafter $-18^{\circ}C$ for 11 days(control group). Sample I group was treated by daily direct moxibustion to bilateral Shinsu(BL23) from the 22nd day to the 25th day for 4 days under the same condition with the control group. Sample II group was treated by daily direct moxibustion to bilateral non-acupoints near the root of the tail from the 22nd day to the 25th day for 4 days under the same condition with the control group. And RBC, WBC, CD4+ T cell count, T3, T4 and TSH were measured. The results were as follows; 1. RBC increased with statistical significance in the sample I and sample II groups compared with the control group. 2. WBC increased with statistical significance in the sample I group, but there was not any significance in the sample II group compared with the control group. 3. Lymphocyte increased with statistical significance both in the sample I and sample II groups compared with the control group. 4. CD4+ T cell count increased with statistical significance both in the sample I and sample II groups compared with the control group. 5. T3, T4 and TSH increased respectively with statistical significance in the sample I and sample II groups compared with the control group.

• Journal of Sasang Constitutional Medicine
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• v.11 no.2
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• pp.377-383
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• 1999

The anemia which is accompanied with chronic primary diseases has been showed most frequently in the clinic. The purpose of this study is to give an account of the effects of the Korean herbal medicine therapy which is based on the constitutional medicine for the patient who has suffered from mild anemia, pneumonia and general depressed condition in the chronic stage of post-cerebellar hemorrhage. The subject is a 75-year-old woman who has had the symptoms caused by hemorrhage, which are headache, dizziness, walking disturbance, dysphasia, and general weakness and so forth. Therefore, she has normocytic normochromic anemia in the hematomancy. We have diagnosed her as Soeumin(少陰人) Ulkwangjeung(鬱狂症) and have prescribed Palmulgunjatang(八物君子湯) in accordance with the principle of Seungyangikgi(升陽益氣). The consequence is that the accompanied anemia and genseal depressed condition have improved.

• Microbiology and Biotechnology Letters
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• v.10 no.3
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• pp.177-184
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• 1982

Studies were carried out to investigate the optimal culture conditions for the production of penicillinase using a strain of Streptomyces sp. isolated from soil, YS-40. Among the carbon and nitrogen sources, glucose and L-asparagine increased the peniciilinase production. The addition of M $n^{＋＋}$, $Ca^{＋＋}$ and L $i^{＋}$ increased the enzyme production, but depressed by F $e^{＋＋＋}$, F $e^{＋＋}$, $Mg^{＋＋}$, Z $n^{＋＋}$, A $g^{＋＋}$, $Ba^{＋＋}$ and S $n^{＋＋}$. L-Leucine slightly increased the enzyme production but L-histidine, L-methionine depressed. Among the vitamins riboflavine, i-inositol, hesperidine, niacin-amide, biotin, folic acid, DL-$\alpha$-lipoic acid increased the enzyme formation. The addition of cephradine, cephalexin, ampicillin, cloxacillin more increased the enzyme formation than that of other$\beta$-lactam antibiotics and antibiotics. Optimal pH and temperature on the enzyme formation was pH 7.0 and 28$^{\circ}C$ respectively Amount of the enzyme production reached at maximum with incubation for 3 days on the optimal condition.

• The Journal of Korean Academic Society of Nursing Education
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• v.10 no.2
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• pp.194-204
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• 2004

The purpose of this study was to provide the basic data needed to create more desirable psychological home environment and the prevention and relief of depression by examining the relations between psychological home environment and depression with the subjects of high school students. The study materials included standard questionnaires made up of forty two questions on psychological home environment by Dr. Jeong, Won-sik(1981), twenty one questions on depression indicators by Beck(1969). Collected data were analyzed by using SPSSWIN 10.0 Program through frequency, percentile, mean, standard deviation, t-test, ANOVA, Scheffe's test, and Pearson correlation coefficient. The main results of this study were as follows; Out of 210 perfect scores for the psychological home environment of the subjects, the mean was $140.54{\pm}11.21$, opening was $41.02{\pm}5.67$, affection was $37.59{\pm}5.80$, autonomy was $35.45{\pm}4.85$, and achievement was $26.48{\pm}6.79$. The depression of the subjects were slight, showing $13.78{\pm}9.73$, with normal condition (0-9scores) 40.0%, slight depression(10-15scores) 23.3%, mild depression(16-23scores) 20.3%, severe depression(24-63scores) 16.4%. The analyses of the relation between psychological home environment and depression of the subjects reveal that achievement-depression(r=.192, p=.000), opening-depression (r=-.296, p=.000), affection-depression(r=-.377, p=.000), and autonomy-depression(r=-.341, p=.000) has all meaningful relations. In summary, these data can be interpreted that high school students were likely to feel more depressed when they recognized their own home environment as under the burden of achievement, and to feel less depressed when they recognized it as open, affectionate, and autonomous.

• Journal of Oriental Neuropsychiatry
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• v.21 no.2
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• pp.201-214
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• 2010

Y$\grave{u}$zh$\grave{e}$ng(鬱證) comes from obstruction of qi by stress. The patient has depressed mood, irritable sign, chest discomfort, costal pain, angry state or some strange feeling on the throat. Oh-Ji-Sang-Seung(五志相勝) therapy is base on the theory of interrelation in five elements in oriental medicine. The contents of Oh-Ji-Sang-Seung(五志相勝) therapy include five subjugations of five emotions. Anxiety subjugates fear(思勝恐), fear subjugates joy(恐勝喜), joy subjugates pity(喜勝悲), pity subjugates anger(悲勝怒), and anger subjugates anxiety(怒勝思). Forgiveness program is a kind of psychological therapies to decrease the degree of anger and it is included in Oh-Ji-Sang-Seung(五志相勝) therapy. In this case, a female patient, 50 years old, who suffered from Y$\grave{u}$zh$\grave{e}$ng(鬱證) with chest discomfort, irritable sign, easily angry state, depressed mood, hot flush, insomnia. We used Oh-Ji-Sang-Seung(五志相勝) therapy besides herbal medication, acupuncture to her condition got improved. Therefore we reported it for the treatment.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.9 no.6
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• pp.1818-1824
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• 2008

This study is focused on the effects of one's blood type on emotional character of children, by comparing each individual's brain wave. Observed records are from those kids who volunteered for KRIJUS(Korea Research Institute of Jungshin Science)'s brain wave measurement from September 2005 to December 2007. The whole 3018 kids(4-7) group consists of 1322 female and 1696 male. Blood types are A>B>O>AB dominately ordered. The relations between depressive attitude and blood type of an infant couldn't be found among female. However, male type B had the most numbers of activeness character while type O shown largest rate of depressed condition. Also, the result amongst infant had shown male type B had the most active-positive rate while type AB took large for depressed-negative. The result had shown no relative connection for activity inclination. Third, among the kids type O had highest awareness rate while type A had lowest. This study revealed meaningful relation between blood types and emotional character among several categories, while suggesting follow-up researches figuring out more detailed explanations for its effect and genetic role.