• 생명과학회지
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• 제33권10호
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• pp.776-782
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• 2023

Silymarin은 간 보호, 항산화, 항염, 항암 등 다양한 생리 활성을 나타내는 것으로 보고되었고, 본 연구에서는 산화 스트레스에 대한 항산화 잠재력과 그 기전을 세포 생존력 및 활성산소종 생성 분석과 Western blot 분석을 통해 RAW 264.7 세포에서 알아보고자 하였다. Silymarin은 세포 독성 없이 lipopolysaccharide(LPS)에 의해 자극된 세포 내 활성산소종을 농도 의존적으로 소거하였다. 그리고 항산화 효과를 보여주는 것으로 알려진 제2상 효소 중 하나인 heme oxygenase (HO)-1의 발현은 silymarin 처리에 의해 강하게 유도되었다. 또한 silymarin 처리는 항산화 효소의 전사인자인 nuclear factor-erythroid 2 p45-related factor (Nrf)-2의 발현을 유의미하게 유도하였고, 이는 HO-1 발현증가와 일치하였다. 세포내 산화와 환원 항상성 조절과 관련된 신호 전달물질인 mitogen activated protein kinase (MAPK)와 phosphoinositde 3-kinase (PI3K)의 인산화 정도 또한 Western blot으로 분석하였고, 그 결과 silymarin 은 p38 MAPK 인산화에 의해 HO-1 발현을 유도하는 것으로 나타났다. 그리고 tert-butyl hydroperoxide (t-BHP)를 이용하여 세포내 지질 과산화를 유도함으로써 silymarin에 의해 유도된 HO-1의 항산화 효과를 확인하였다. 그 결과 silymarin 처리에 의해 세포사멸이 유의적으로 억제되었고, p38의 선택적 저해제를 처리한 세포군에서는 t-BHP에 의해 유의적인 세포사멸이 발생하였다. 이 결과를 통해 silymarin은 Nrf-2/p38 MAPK 신호 전달 경로를 통해 HO-1의 발현을 유도하고, 이를 통해 항산화 효과를 높이는 것을 확인할 수 있었다.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제50권1호
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• pp.27-34
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• 2024

Objectives: Surgical intervention for removal of an impacted third molar can lead to significant pain and swelling. Corticosteroids show promise for mitigating postoperative sequelae across various surgical contexts. The use of corticosteroids following minor oral surgery, though controversial, has already been proven effective. However, little research has explored peroral prescription of corticosteroids despite its convenience for outpatients and for non-surgeons like implantologists and periodontists and others who don't have access to needle injections. The aim of this study was to address a void in the literature by comparing the effects of two styles of preoral administration of prednisolone after surgical removal of the mandibular third molar and to determine which style minimizes postoperative sequelae. Materials and Methods: A randomized, split-mouth clinical study was conducted to investigate the efficacy of two different styles of preoral prednisolone in mitigating postoperative sequelae following surgical extraction of impacted mandibular third molars. Fifteen participants were enrolled in the study. Random selection was used to determine the prescription style for the right and left mandibular arch. Group A included those who received a single dose of prednisolone 25 mg, while group B received prednisolone 5 mg postoperatively for a period of three days (5 mg three times/day on the first postoperative day, 5 mg twice/day on the second postoperative day; 5 mg once/day on the third postoperative day). Results: There was a significant difference in the distance between the corner of the mouth and tragus, which decreased with the time interval with respect to group B when compared to group A. Conclusion: The present study showed that a three-day tapered dose of prednisolone postoperatively was more effective in reducing post-extraction sequelae than a single-dose regimen.

• Journal of Nutrition and Health
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• 제10권2호
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• pp.59-70
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• 1977

This study was designed to evaluate the changes and improvements in the Korean diet during the last thirty years (since independence in 1945), and to make recommendations for the improvement of their nutritional status, consequently contributing to the physical and mental welfare of the Korean people. The results and recommendations are as follows: 1. The total calorie and carbohydrate intake decreased by $8{\sim}12%$ in the 1970's, as compared with the 1940's and the 1950's. 2. The intake of calcium and vitamiu A increased $30{\sim}50%$ and $20{\sim}60%$ respectively in the 1960's and 1970's as compared with the 1940,s. But this intake level is still lower than the RDA values. 3. The vitamin C intake was somewhat higher in the mountainous and farming areas than in urban areas. 4. In the 1970's, the decrease of untriend intake due to seasonal variation was marked especially for protein, niacin, vitamin $B_1$, and vitamin C. 5. The consumption of protein foods (meats and legumes) increased in an amount of $15{\sim}36g$ per day. There was a marked increase in the intake of meat in farming areas and of milk in urban areas in the 1970's. This increased intake of animal proteins is a very desirable dietary change. 6. The cereal consumption was lowest in urban areal, but there was a general decrease in the intake of the cereal group in the entire area in the 1970's. For the farmers, the intake of cereal food decreased most, from 750 g to 576 g, but cereals still composed a high proportion of the entire diet. 7. Fruits and vegetables showed the highest intake for the urban people, as expected. For the whole area, this food group showed an increase of 8.7% in the 1970's, as compared with the 1960's. 8. The gradual ihcrease in the intake of the fats and oil group was a desirable dietary change. but the absolute amount was too low. 9. A 7% increase in height and a 9% incrrase in weight for growing children and adolescents was observed in the 1970's as compared with the 1940's, but several kinds of deficiency diseases, such as nutritional anemia and dental caries were still apparent in many areas. 10. To improve cur food life and to cope with food shortages faced in Korea, an efficient and nationwide nutrition education program should be implemented. This would maximize efficiency of intake from the limited food sources for a balanced diet. 11. As it is of utmost importance to provide growing children with a desirable physical, sccial mental, and especially nutritional environment, a well-planned and organized school feeding program should be practiced widely and efficiently. 12. Young mothers and pregnant women should be educated on the importance of their children's nutrition, especially for the critical fetal and infancy periods. 13. More thorough and continuous nutritional survey studies on the changes in dietary patterns for the entire nation should be pursued, evaluated and documented. This would Provide a good information guide for future nutritional study programs. 14. It is the nutritionistist's strong desire that national leaders, especially decision makers recognize the fact that improvement of the nutritional status of the People is one of the most economic and preventative ways of improving their physical and mental health. This is closely related to the economic development and strength of the nation.

• 대한치과보철학회지
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• 제43권4호
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• pp.528-543
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• 2005

Statement of problem: Repeated delivery and removal of abutment cause some changes such as wear, scratch or defect of hexagonal structure. It may increase the value of rotational freedom(RF) between hexagonal structures. Purpose: The purpose of this study was to evaluate surface changes and rotational freedom between the external hexagon of the implant fixture and internal hexagon of abutment after repeated delivery and removal under SEM and toolmaker's microscope. Materials and methods: Implant systems used for this study were 3i and Avana. Seven pail's of implant fixture, abutment and abutment screws for each system were selected and all fixtures were perpendicularly mounted in liquid unsaturated polyesther with dental surveyor. Each one was embedded beneath the platform of fixture. Surfaces of hexagonal structure before repeated closing and opening of abutment were observed using SEM and rotational freedom was measured by using toolmaker's microscope. Each abutment was secured to the implant future by each abutment screw with recommended torque value using a digital torque controller and was repeatedly delivered and removed by 20 times respectively. After experiment, evaluation for the change of hexagonal structures and measurement of rotational freedom were performed. Result : The results were as follows; 1. Wear of contact area between implant fixture and abutment was considerable in both 3i and Avana system. Scratches and defects were frequently observed at the line-angle of hexagonal structures of implant fixture and abutment. 2. In the SEM view of the external hexagon of implant fixture, the point-angle areas at the corner edge of hexagon were severely worn out in both systems. It was more notable in the case of 3i systems than in that of Avana systems. 3. In the SEM view of the internal hexagon of abutment, Gingi-Hue abutment of 3i systems showed severe wear in micro-stop contacts that were machined into the corners to prevent rotation and cemented abutment of Avana systems showed wear in both surface area adjacent to the corner mating with external hexagon of implant fixture. 4 The mean values of rotational freedom between the external hexagon of the implant fixture and internal hexagon of abutment were 0.48$\pm$0.04$^{\circ}$ in pre-tested 3i systems and 1.18$\pm$0.25$^{\circ}$ after test, and 1.80$\pm$0.04$^{\circ}$ in pre-tested Avana systems and 2.61$\pm$0.16$^{\circ}$ after test. 5. Changes of rotational freedom after test shouted statistical)y a significant increase in both 3i and Avana systems(P<0.05, paired t-test). 6. Statistically, there was no significant difference between amount of increase in the rotational freedom of 3i systems and amount of increase in that of Avana ones(P>0.05, unpaired t-test). Conclusion: Conclusively, it was considered that repeated delivery and remove of abutment by 20 times would not have influence on screw joint stability. However, it caused statistically the significant change of rotational freedom in tested systems. Therefore, it is suggested that repeated delivery and remove of abutment should be minimal as possible as it could be and be done carefully Additionally, it is suggested that the means or treatment to prevent the wear of mating components should be devised.

• Restorative Dentistry and Endodontics
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• 제31권5호
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• pp.390-397
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• 2006

이번 연구는 서로 다른 4개의 전자근관장측정기의 정확성을 측정하고 각각 0.5지점과 Apex지점에서의 일관성을 비교하고자 하였다. 40개의 발치된 상하악 소구치를 대상으로 치수강 개방 후 alginate model에 고정시키고 근관장을 측정하였다. 사용된 전자근관장측정기는 Root ZX (Merits, Tokyo, Japan), SmarPex (META, Seoul, Korea). Elements Diagnostic Unit (SybronEndo, CA, USA), E-Magic Finder Deluxe (S-Denti, Seoul, Korea)이다. 먼저 모든 치아에서 4개의 전자근관장측정기를 사용하여 0.5지점과 Apex지점에서 근관장을 측정하여 한 치아당 8개의 측정값을 얻었다. 다음으로 치아를 각 전자근관장측정기당 10개씩 4개의 그룹으로 나누어, 각각 제조사의 지시대로 Root ZX, Elements Diagnostic Unit 및 E-Magic Finder Deluxe는 "0.5"지점에서, SmarPex는 "Apex"지점에서 file을 치아에 cement로 고정시켰다. 이후 치근단부 4 mm를 삭제하여 100배율의 Image Proplus로 관찰하여 file 끝에서 주근단공의 외연까지의 실제거리를 측정한 후, 4개의 전자근관장측정기의 0.5지점 및 Apex지점에서 file끝과 주근단공 사이의 거리를 계산하여 비교하였다. 그 결과 Root ZX와 E-Magic Finder는 실험군 100%, SmarPex는 90%, Elements Diagnostic Unit는 70%에서 주근단공과의 거리가 임상적 허용범위인 ${\pm}0.5 mm$이내에 있었다. 또한 각 전자근관장측정기 마다 0.5지점과 Apex지점에서의 근관장의 표준편차와 사분위 범위를 구하여 두 지점간의 일관성을 비교한 결과, Root ZX, E-Magic Finder는 0.5지점과 Apex지점에서 비슷한 일관성을 보였으며 SmarPex와 Elements Diagnostic unit는 Apex지점에서 0.5지점보다 더 높은 일관성을 보였다. 전자근관장측정기는 근관 내의 조건에 관계없이 근첨협착부에서 항상 일정한 거리를 재현해 낼 수 있는 일관성이 중요하므로, 이렇게 0.5지점 또는 Apex지점에서의 일관성이 증명된다면 실제 임상에서 사용할 때 전자근관장에서 일정한 거 리를 가감하여 사용할 수 있다.

• 대한치과보철학회지
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• 제43권2호
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• pp.158-175
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• 2005

Statement of problem. Every effort has been continually made to obtain objectivity in measuring the longevity of fixed restorations, such as by establishing unified judgement standard for deciding success and adopting statistical method that analyzes the data of successful and failed cases at the same time. In Korea, however desired level of development has not to be made in this field yet. Purpose. This study, adopting California Dental Association (CDA) quality evaluation system, established objective standard for deciding success, and inferred the longevity of fixed restorations and their failure analysis through adopting Kaplan-Meier survival analysis. Material and method. In order to assess the longevity of flxed restorations serviced in Korea and causes of failure, a total of 1109 individuals (aged 15-74, 716 women and 393 men loaded with 2551 unit fixed restorations, and 1934 abutments) who lived in Kyung-In Province were examined and the findings were as follows : Results. 1. Length of service of fixed restorations serviced in Korea was 6.86$\pm$0.15 yr (mean), 5.5 yr (median), and the rate of success was 65.82% in 5 year survival, and 21.15% in 10 year survival. 2. When there was patient's need for replacing old prosthetics, longevity of fixed restorations was 7.51$\pm$0.27 yr (mean), 7 yr (median), and the rate of success was 61.08% in 5 year survival, and 17.57% in 10 year survival. 3. Longevity of fixed restorations was longest in the over-sixty age group(9.21$\pm$0.66) and that of the teen age group(3.39$\pm$0.28) was shortest (p<0.05). 4. Longevity of fixed restorations of women (7.38$\pm$0.18 years) was longer than that of men (6.00$\pm$0.26) (p<0.05). 5. As for the provider factor (such as unlicensed performers, university hospitals, and private clinic), there was no statistically significant difference in longevity of fixed restorations. 6. Defective margin (34.78%). periodontal disease (12.15%), periapical involvement (11.73%), was the most frequent causes of failure and poor esthetics group showed the longest life above all (p<0.05). Actual frequent causes of failure after removing old prosthetics were defective margin, periapical involvement, periodontal disease and uncemented restoration. In 75.67% of the cases, abutment state after removing old prosthetics was good enough for loading another prosthetics. 7. There was found to have statistically significant influence between longevity of single crown (6.35$\pm$0.20 yr) and that of 3 unit fixed restorations (7.60$\pm$0.30 y) (p<0.05). In each case the most frequent cause of failure was defective margin. 8. The number of cantilever pontic, pontic/abutment ratio, oral hygiene status were found to have no statistically significant influence on longevity of fixed restorations in all groups (p>0.05). 9. Longevity of fixed restorations made of non precious metal was longest (9.60$\pm$0.40 yr) semi precious and precious trailing behind(p<0.05). 10. Group function group (37.04%) and partial group function group (44.62%) were predominant in frequency but showed no correlation between them and among different types of occlusal plane and different types of occlusal surface (p>0.05). 11. Longevity of fixed restorations was longest in the centric interference group(9.35$\pm$0.62) (p<0.05) among different types of occlusal interference. Conclusion. We found that longevity of fixed restorations serviced in Korea is affected by age, gender and type of material, and that most frequent cause of failure is defective margin. In order to assess the accurate longevity of axed restorations, unified research design. overcoming inter-observer difference and establishing the objective research items are needed. Furthermore, it is thought that prospective approach through thorough study and regular follow-ups is needed just from the start of research. Nationwide detailed studies on length of service of fixed restorations manufactured in Korea are hoped to be conducted hereafter.

• 대한치과교정학회지
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• 제40권1호
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• pp.16-26
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• 2010

다양한 열가소성 교정 재료를 이용한 성공적인 임상 결과가 보고되었지만, 재료의 물리적 성질에 관한 연구는 많지 않다. 본 연구는 열가소성 재료의 종류, 두께, 변형량과 반복변형에 따른 변형 시 필요한 하중과, 변형되었던 재료가 원래의 상태(resting position)로 돌아갈 때 재료의 복원력을 평가하였다. 실험적인 모델의 조건에서 투명교정장치의 재료로 쓰이는 4가지 종류의 열가소성 재료(0.5 mm, 0.75 mm, 1.0 mm 두께)를 최종 변형량이 2.0 mm가 될 때까지의 하중(gf)을 측정하였다. 변형 후 탄성력에 의해 원점으로 회복될 때, 재료의 복원력(gf/$mm^2$)을 측정하였다. 동일한 방법으로 5회 반복변형 동안의 하중과 복원력의 변화를 측정하였다. 그 결과, 열가소성 재료의 두께와 변형량에 대해 상호 교호작용이 관찰되었으며 (p < 0.05), 열가소성 재료의 두께 및 변형량이 하중과 복원력에 가장 큰 영향력을 나타내었고 재료 간 혹은 제품 간의 하중과 복원력에는 유의한 차이가 없었다. 두께가 1.0 mm이거나 또는 1.0 mm 이상 변형인 경우 최소 159 gf의 하중이 필요하였고, 최소 16 gf/$mm^2$의 복원력이 발생하였다. 각 실험군에 대한 반복하중 시 하중과 복원력에서 유의한 차이가 관찰되었고 (p < 0.01), 평균 10 - 17%의 하중 감소와 4 - 7%의 복원력 감소가 관찰되었다. 이상의 결과, 하중과 복원력에 가장 영향을 많이 주는 요소는 재료의 두께와 치아의 이동량 이었다. 제품에 상관없이 두께가 1.0 mm 이상인 재료를 사용하거나 치아를 1.0 mm 이상 이동 시에는 과도한 힘이 발생하였다. 따라서 투명교정장치를 이용하여 생리적으로 치아를 이동시키기 위해서는 초기 치아배열을 위해 사용하는 열가소성 재료의 두께와 셋업 시 치아 이동량을 고려하여 과도한 힘이 가해지지 않도록 해야 한다. 또한 반복하중 후에 열가소성 재료의 피로도에 의한 힘의 상쇄를 고려하여 임상에 적용해야 한다.

• 구강회복응용과학지
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• 제24권3호
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• pp.269-281
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• 2008

골유착성 임플란트 보철물에서 피로나 과하중에 의해 보철유지 나사나 지대주 나사의 파절, 보철물의 파절, 또는 고정체의 파절 등과 같은 기계적 강도와 연관된 문제점이 발생할 가능성이 높다. 임플란트 시스템의 기계적인 강도에 영향을 주는 요소에는 고정체와 나사의 직경, 재료적 특성, 연결부 디자인, 지대주 디자인 등이 있으며, 이 중 임플란트 고정체와 지대주간의 연결부 디자인은 임플란트 시스템의 기계적인 연결상태와 연결부 안정성을 결정하는 주요소이다. 대부분의 기계적 강도에 관한 연구에서처럼 단일하중에 의한 압축굽힘강도나, 단기적인 반복하중 후의 결과만을 평가하여 임플란트 시스템의 장기적인 안정성을 예측하기에는 한계가 있다. 연구 목적: 이에 본 연구에서는 external butt joint와 internal conical joint를 갖는 임플란트 시스템(오스템사)의 연결부 디자인에서 각각 다른 두 가지 지대주를 사용하여, 연결부 및 지대주 디자인이 기계적 강도에 미치는 영향을 압축굽힘강도는 물론 내구성한계를 측정하여 알아보고자 하였다. 연구 재료 및 방법: External butt joint인 US II에서는 통상적인 UCLA 지대주 형태의 Cemented abutment(BJT)와 굽힘 저항성을 증가시키기 위해 나사 두부가 지대주 상단에 위치하도록 설계된 Safe abutment(BJS)를, internal conical joint인 SS II에서는 one-piece형의 Solid abutment(CJO)와 two-piece형의 ComOcta abutment(CJT)를 지대주로 사용하였다. ISO 규정을 참고하여 단일 임플란트, 변연골 흡수, 그리고 $30^{\circ}$ 경사하중 조건에서 압축굽힘강도와 내구성한계를 측정하였고 실패 양상을 관찰한 결과 다음과 같은 결론을 얻었다. 결과 및 결론: 1. 압축굽힘강도는 BJS군(1392.0N), CJO군(1261.8N), BJT군(1153.2N), 그리고 CJT군(1110.2N) 순으로 낮아졌으며(P<.05), CJT군과 BJT군 사이에는 차이가 없었다(P>.05) 2. 내구성한계는 CJO군(600N), CJT군(453N), BJS군(360N) 그리고 BJT군(300N) 순으로 낮아졌다. 3. 압축굽힘강도는 연결부 디자인 또는 지대주 디자인에 따라 차이를 보였으며, 내구성한계에 있어서는 연결부 디자인이 더 주된 요소로 작용하였다.

• 대한치과보철학회지
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• 제41권2호
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• pp.182-206
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• 2003

Statement of problem : Successful osseointegration of endosseous threaded implants is dependent on many factors. These may include the surface characteristics and gross geometry of implants, the quality and quantity of bone where implants are placed, and the magnitude and direction of stress in functional occlusion. Therefore clinical quantitative measurement of primary stability at placement and functional state of implant may play a role in prediction of possible clinical symptoms and the renovation of implant geometry, types and surface characteristic according to each patients conditions. Ultimately, it may increase success rate of implants. Purpose : Many available non-invasive techniques used for the clinical measurement of implant stability and osseointegration include percussion, radiography, the $Periotest^{(R)}$, Dental Fine $Tester^{(R)}$ and so on. There is, however, relatively little research undertaken to standardize quantitative measurement of stability of implant and osseointegration due to the various clinical applications performed by each individual operator. Therefore, in order to develop non-invasive experimental method to measure stability of implant quantitatively, the resonance frequency analyzer to measure the natural frequency of specific substance was developed in the procedure of this study. Material & method : To test the stability of the resonance frequency analyzer developed in this study, following methods and materials were used : 1) In-vitro study: the implant was placed in both epoxy resin of which physical properties are similar to the bone stiffness of human and fresh cow rib bone specimen. Then the resonance frequency values of them were measured and analyzed. In an attempt to test the reliability of the data gathered with the resonance frequency analyzer, comparative analysis with the data from the Periotest was conducted. 2) In-vivo study: the implants were inserted into the tibiae of 10 New Zealand rabbits and the resonance frequency value of them with connected abutments at healing time are measured immediately after insertion and gauged every 4 weeks for 16 weeks. Results : Results from these studies were such as follows : The same length implants placed in Hot Melt showed the repetitive resonance frequency values. As the length of abutment increased, the resonance frequency value changed significantly (p<0.01). As the thickness of transducer increased in order of 0.5, 1.0 and 2.0 mm, the resonance frequency value significantly increased (p<0.05). The implants placed in PL-2 and epoxy resin with different exposure degree resulted in the increase of resonance frequency value as the exposure degree of implants and the length of abutment decreased. In comparative experiment based on physical properties, as the thickness of transducer increased, the resonance frequency value increased significantly(p<0.01). As the stiffness of substances where implants were placed increased, and the effective length of implants decreased, the resonance frequencies value increased significantly (p<0.05). In the experiment with cow rib bone specimen, the increase of the length of abutment resulted in significant difference between the results from resonance frequency analyzer and the $Periotest^{(R)}$. There was no difference with significant meaning in the comparison based on the direction of measurement between the resonance frequency value and the $Periotest^{(R)}$ value (p<0.05). In-vivo experiment resulted in repetitive patternes of resonance frequency. As the time elapsed, the resonance frequency value increased significantly with the exception of 4th and 8th week (p<0.05). Conclusion : The development of resonance frequency analyzer is an attempt to standardize the quantitative measurement of stability of implant and osseointegration and compensate for the reliability of data from other non-invasive measuring devices It is considered that further research is needed to improve the efficiency of clinical application of resonance frequency analyzer. In addition, further investigation is warranted on the standardized quantitative analysis of the stability of implant.

• 직업교육연구
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• 제35권4호
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• pp.19-46
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• 2016

이 연구의 목적은 사회적 수요가 증가하는 특성화고등학교 간호과 교육의 운영 현황과 교육과정 편성 운영, 교육환경 등에 대한 현황을 분석하고 간호과 교육의 개선 방향을 탐색하는데 목적이 있다. 이 연구의 방법은 관련 선행연구를 분석하고 학교알리미, 교육통계연보 등 간호관련 학과 개설 및 운영 현황 자료, 학교 교육과정, 각 기관 및 협회의 홈페이지에 소개된 공시 자료 등을 수집 분석하였다. 이 연구의 주요 결과는 다음과 같다. 첫째, 2016년 1학기 현재 특성화고등학교 중에 간호과를 개설 운영하는 학교는 총 38개교로 전체 특성화고 마이스터고의 약 6.4% 정도이다. 이들 학교는 주로 보건간호과, 치의보건간호과, 간호과, 의료간호관광과. 간호회계 및 간호경영과 등의 명칭으로 개설하였다. 간호과 졸업생은 2012년 이후 취업률과 진학률간의 격차가 좁혀지고 있으며 2015년에는 특성화고등학교 전체 평균 취업률인 46% 수준이었다. 둘째, 특성화고등학교 간호과는 인력양성 목표를 간호조무사 양성에 두고 관련 취득 자격으로 간호조무사, 요양보호사 등을 주로 제시하고 있었다. 간호과 교육과정은 자격 취득 요건, 현장 직무 수행에서 필요한 역량과 관련한 과목들을 편성하고 있었으나 간호과 교육과정의 충분성, 자격과 교육과정 편성과의 정합성 등을 검토해야 한다. 법적 요건인 780시간의 현장실습은 주로 1학년부터 2학년까지 3번의 방학을 통해 병의원 현장에서 별도의 교육과정으로 운영되고 있었다. 셋째, 간호과 교육의 물적 환경은 전공별로 2개 정도의 실습실과 학생 규모를 고려한 시도교육청의 시설설비 기준을 적용하여 비교적 기본 환경을 구축 활용하고 있었다. 인적 환경인 교사 확보는 간호 표시과목이 없음에 따라 표시과목의 개설, 지역별 배치 기준의 검토, 전문성 함양을 위한 연수 및 연구, 장학의 지원을 위한 개선이 시급한 것으로 나타났다.