• Journal of The Korean Society of Integrative Medicine
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• v.12 no.2
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• pp.25-32
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• 2024

Purpose: This study utilizes big data from the 8th (2021) National Health and Nutrition Examination Survey to determine first, the relationship between chewing discomfort in the elderly and some systemic diseases and second, whether oral diseases and oral health problems are related to systemic diseases. Since this may have an impact, we aim to provide basic data to facilitate the expansion and emphasize the importance of integrated health management education. Methods: Original data from the 8th (2021) National Health and Nutrition Survey, conducted by the Korea Centers for Disease Control and Prevention, were analyzed using SPSS Version 21.0 (IBM). A complex sample frequency analysis was conducted to confirm the general and health-related characteristics of the study subjects, and a complex sample cross-analysis was conducted to determine chewing discomfort according to both general and health-related characteristics. Complex sample multiple logistic regression analysis was conducted to determine the effect on chewing discomfort. Results: In order to analyze the factors that affect chewing discomfort, the general characteristics that showed significant differences in chewing discomfort were adjusted for age, personal income, education level, basic livelihood security, high blood pressure, subjective health status, and subjective oral health. It was found that the condition had a statistically significant effect on chewing discomfort. Conclusion: The findings of this study demonstrate that high blood pressure, subjective health status, and subjective oral health status affect chewing discomfort; hence, measures such as developing and operating programs to improve national oral health are needed. We hope that our study will be used as basic data for research into chewing discomfort and systemic diseases in the elderly.

• Journal of Ginseng Research
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• v.37 no.1
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• pp.54-63
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• 2013

Ginsenoside Rd is a primary constituent of the ginseng rhizome and has been shown to participate in the regulation of diabetes and in tumor formation. Reports also show that ginsenoside Rd exerts anti-oxidative effects by activating anti-oxidant enzymes. Treatment with ginsenoside Rd decreased nitric oxide and prostaglandin $E_2$ ($PGE_2$) in lipopolysaccharides (LPS)-challenged RAW264.7 cells and in ICR mouse livers (5 mg/kg LPS; LPS + ginsenoside Rd [2, 10, and 50 mg/kg]). Furthermore, these decreases were associated with the down-regulations of inducible nitric oxide synthase (iNOS) and cyclooxygenase (COX)-2 and of nuclear factor (NF)-${\kappa}B$ activity in vitro and in vivo. Our results indicate that ginsenoside Rd treatment decreases; 1) nitric oxide production (40% inhibition); 2) $PGE_2$ synthesis (69% to 93% inhibition); 3) NF-${\kappa}B$ activity; and 4) the NF-${\kappa}B$-regulated expressions of iNOS and COX-2. Taken together, our results suggest that the anti-inflammatory effects of ginsenoside Rd are due to the down-regulation of NF-${\kappa}B$ and the consequent expressional suppressions of iNOS and COX-2.

• Journal of Periodontal and Implant Science
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• v.37 no.1
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• pp.35-44
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• 2007

Periodontal ligament (PDL) is the connective tissue located between the tooth root and alveolar bone. In a previous study, PDLs22 was isolated as a PDL-specific gene by using subtractive hybrid-ization between cultured PDL fibroblasts and gingival fibroblasts. It was also suggested that PDLs22 plays important roles in the development, differentiation and maintenance of periodontal tissues. However, little is known about functional study of PDLs22 using recombinant protein in PDL fibroblast differentiation and periodontium formation. In this study, in order to produce the PDLs22 recombinat protein, PDLs22 expression vector were constructed and expressed its protein in various host cell and temperature conditions. The results were as follows: 1. PDLs22 protein was not strongly expressed In the induction system using pRSET-PDLs22 construct. 2. When the BL21(DE3) pLysS was used as a expression host, PDLS22 protein was strongly ex-pressed in the induction system using pHCEIIBNd-PDLs22 construct. 3. The PDLs22 protein was recognized at a molecular weight of 28 kDa in western blots. 4. Almost of the expressed PDLs22 protein was not soluble and observed like as inclusion body. 5. The protein solubility was not improved after modification of induction time and temperature during PDLs22 protein production. In this study, the system for the PDLs22 protein production was connstructed. However, the re-results suggest that further studies will be needed to produce the considerable amount of PDLs22 re-combinat protein, which can use for the periodontal regeneration.

• Journal of Digital Convergence
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• v.19 no.5
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• pp.449-460
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• 2021

The purpose of this study explained the experience of volunteering activities and the relationship of subjective self-awareness in order to examine the social meaning of volunteer activities. For adults aged 20 or older, 312 volunteering experience and social support awareness were analyzed on the level of self-identity by allocation sampling method depending on gender and age. The analysis results of this study were as follows. First, it was found that those who have experienced volunteer activitiies have a relatively simple willingness to participate in professional volunteer activities and those who have experienced volunteer activities. Second, social support and self-identification were different depending on whether they have experienced volunteer activities. Third, age, volunteer participation, willingness to participated in volunteering, and social support were analyzed as explanatory factors predicting self-identification of research participants. Based on the research results, volunteer activities to positively promote self-awareness suggested the need to practice volunteer activities according to the life cycle so that social meaning can be given. As a policy suggestion, the need for volunteer activities was closely analyzed to enable healthy self-forming for well-aging from adulthood to old age to discussed the need for policies and systems to strengthen volunteer motivation as leisure activities.

• Journal of Dental Rehabilitation and Applied Science
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• v.29 no.1
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• pp.101-110
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• 2013

$T4K^{TM}$(Myofunctional Research Co, Australia) is one of the myofunctional appliance developed to be used in children of mixed dentition. Myofuncitonal appliance stimulate the facial, masticatory and tongue muscle and help to balance the muscular force. Labial bow included in the device exerts strength in excessively labial inclineded upper jaw, Lip bumper blocks strength of the mouth to prevent abnormal strength exerted in lower jaw, Tongue tag secures proper position of tongue, and additional exercise is not required for child patients. For the more, simpler design and softer texture of device prmoted cooperation of patients during use. This case report is to present the satisfactory results gained by using $T4K^{TM}$ on Class II patients. Comment 1. $T4K^{TM}$ was applied in Class II malocclusion patients of mixed dentition with expected space insufficient to gain facial improvement. 2. Excessive overjet, overbite were improved. 3. Main effects are regarded to have been achieved by development of lingual slant of upper jaw, labial slant of lower jaw, and lower part of jawbone. 4. Bad habits, such as mouth breathing, can also be adjusted.

• The Journal of the Korea Contents Association
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• v.14 no.6
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• pp.271-280
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• 2014

The purpose of this study was to offer basic data for developing effective program for promotion elderly people's oral condition, and oral health behavior upon the appearance of denture. This study was performed by utilizing health questionnaire survey and oral examination survey for first year(2010) law data of the 5th korea national health and nutrition examination survey. The research subjects were 1419 people who were aged over 65 and completed the oral examination and oral questionnaire survey. In the general characteristics, the need of denture was indicated highly in the male elderly. Factors of having relationship with a need of denture in oral health condition were indicated to be chewing difficulty(p<0.001) and dental caries(p<0.0001). The case of not using oral hygiene device was high in a need of denture(p<0.001). Also, a case of not dental treatment was indicated to be high in a need of denture(p<0.001). Through these related findings, the elderly's oral condition and oral health behavior were indicated to have high relationship with a need of denture. There is a need of securing basic data for promoting the elderly's oral health in the future and of seeking a plane for application in order to improve the elderly's health in the aging society. Therefore there is a need of securing and seeking elderly's health program which is considered the aging society's characteristics to improve the elderly's health promotion.

• Applied Microscopy
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• v.32 no.3
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• pp.275-284
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• 2002

Granular gland regeneration in the toad after dorsal skin wound histologically was examined using scanning and transmission electron microscopy. After cutaneous wounds were induced by excision, animals were maintained in special cages for up to 20 days. In transmission electron microscopy (TEM), newly formed granular gland, though poorly developed, was seen on 4 day after injury. Epithelial cells moved toward apical region of newly formed gland. The cells had smooth surface and were not connected to other cells by desmosomes. Mitochondria rich cell (MRC) possessing long cytoplasmic processes formed a gland cavity and hemidesmosomes were found under the cell processes. Basal cavity of newly formed gland consisted of MRC, pro-granular producing cells (pGPC), and granular producing cell (GPC). Moreover it was observed that xanthophores moved to the base of the epithelial tissue on 10 day after the injury. These cells contained numerous pterinosomes and carotenoid vesicles. Immature pterinosomes were large and carotenoid vesicles were moderately electron dense. On 13 day after the injury, xanthophores contained abundant carotinoid vesicles and lammelated pterinosomes. Iridophores were also observed adjacent the developing xanthophores on 16 day post-injury. These observations indicated that regeneration of granular gland from glandular precursor cells during wound healing and subsequent expansion of the glandular cells might be dependent on maturation and proliferation of these newly formed cells.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.22 no.4
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• pp.263-272
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• 2021

This study investigated the oral health knowledge and educational needs of adults by life cycle. We aimed to provide basic data for developing oral health education plans for well -aging. The survey was conducted online and through mobiles by Gallup Korea during February 2021. A total of 319 adults over the age of 19 were surveyed. The study aimed at investigating the general characteristics, the quality of life-related to oral health, knowledge of oral health, and the need for well-aging education. The PASW Statistics ver 18.0 statistical program was used for data analysis. The analysis of the data suggests that prevention was the highest priority among all age groups. Furthermore, there was a difference in the perceived educational need among different age groups. The cause of the youth, the treatment of the middle-aged and the elderly were significantly related to oral and systemic disease. The need for education related to oral diseases was ranked in the order of aches, bad breath, periodontal diseases, and tooth discoloration. For information, the subjects reached out to the internet, dental and medical institutions, and public health centers. The teaching methods experienced by those surveyed included lectures combined with experience, videos, and expert lectures. We believe that this study can be used to develop an education plan that reflects the needs of the subjects when conducting life cycle education for well-aging.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.22 no.3
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• pp.190-198
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• 2021

The purpose of this study is to identify characteristics of well-aging related research conducted in Korea and to analyze the concept definition to present the direction for future well-aging research in Korea. As a research method, an integrated literature review suggested by Whittemore & Knafl was conducted. Study results found research conducted in Korea consisted of 2 literature reviews, case studies, qualitative studies, 3 survey studies, and 2 experimental studies. In addition, there were 3 studies performed prior to 2017 and 8 studies after that included 2 dissertations and 9 dissertations in academic journals. The definition of well aging consisted of physical, emotional, social, economic, and self-realization aspects. Based on the results of this study, it is necessary to provide education and programs according to life cycles to prepare well aging, and in the future, well-aging studies should be conducted in various academic fields.

• Journal of the Korea Convergence Society
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• v.9 no.4
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• pp.85-91
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• 2018

This is a qualitative research that was carried out to analyze the experience of loneliness of the elderly people living alone using the result of focus group interviews. This study conducted interviews with 28 subjects in the Senior Welfare Center of D city. For the purpose, 28 persons were divided into 5 groups, and interviews were carried out with each group for 50-70 minutes. and the voluntary character of research participation was sufficiently explained. As a result of the research, three topic collections consisting of 'Unavoidable lonesomeness', 'Inevitable death', and 'Acceptance of my life' and seven subjects, which consist of 'Absence of spouse', 'Independence for children', 'Death of neighbor (friend)', 'Fear of death left alone', 'Laying down', 'Taking care of my health', and 'Soothing loneliness in my own way', were derived. The elderly persons living alone who participated in this research expressed their feeling of unavoidable loneliness and their effort to overcome the loneliness. Based on the findings of this research, it is hoped that diverse plans to overcome psychological loneliness of the elderly people living alone will be developed.