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Electron microscopic studies on the gonadotropes in the hypophysis of the Korean native goat (한국재래산양 뇌하수체의 성샘자극세포에 관한 전자현미경적 연구)

  • Lee, In-se;Lee, Heungshik S.;Kang, Tae-cheon;Won, Moo-ho
    • Korean Journal of Veterinary Research
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    • v.36 no.4
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    • pp.763-771
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    • 1996
  • Ultrastructures of hypophyseal gonadotropes were studied in the hypophysis of the Korean native goat by electron microscopic immunohistochemistry with antisera to follicle stimulating hormone(FSH) and luteinizing hormone(LH). 1. Gonadotropes in the adenohypophysis were observed in the pars distalis and the pars tuberalis, but not in the pars intermedia. 2. FSH cells were round or oval in shape, and contained two types of round secretory granules, i.e., small and large granules. Small secretory granules were electron-dense and 180-275nm in diameter. Large secretory granules were less electron-dense than small granules and 485-555nm in diameter. 3. LH cells were round or oval in shape and also contained two types of secretory granules, the size of which were smaller than that of FSH cells. Small secretory granules were electron-dense and 160-230nm in size. The size of large secretory granules were 315-415nm with moderate electron densities.

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Effects of Post Annealing and Oxidation Processes on the Shallow Trench Etch Process (Shallow Trench 식각공정시 발생하는 결함의 후속열처리 및 산화곤정에 따른 거동에 관한 연구)

  • 이영준;황원순;김현수;이주옥;이정용;염근영
    • Journal of the Korean institute of surface engineering
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    • v.31 no.5
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    • pp.237-244
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    • 1998
  • In this stydy, submicron shallow trenches applied to STI(shallow tench isolation) were etched using inductively coupled $CI_2$/HBr and $CI_2/N_2$plasmas and the physical and electrical defects remaining on the etched silicon trench surfaces and the effects of various annealing and oxidation on the removal of the defects were studied. Using high resolution electron microscopy(HRTEM), Physical defects were investigated on the silicon trench surfaces etched in both 90%$CI_2$/ 10%$N_2$ and 50%$CI_2$/50%HBr. Among the areas in the tench such as trench bottom, bottom edge, and sidewall, the most dense defects were found near the trench bottom edge, and the least dense defects were found near the trench bottom edge, and least dense defects compared to that etched with ment as well as hydrogen permeation. Thermal oxidation of 200$\AA$ atthe temperature up to $1100^{\circ}C$apprars not to remove the defects formed on the etched silicon trenches for both of the etch conditions. To remove the physicall defects, an annealing treatment at the temperature high than $1000^{\circ}C$ in N for30minutes was required. Electrical defects measured using a capacitance-voltage technique showed the reduction of the defects with increasing annealing temperature, and the trends were similar to the results on the physical defects obtained using transmission electron microscopy.

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The Relationship between Daily Fructose Consumption and Oxidized Low-Density Lipoprotein and Low-Density Lipoprotein Particle Size in Children with Obesity

  • Gungor, Ali;Balamtekin, Necati;Ozkececi, Coskun Firat;Aydin, Halil Ibrahim
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.24 no.5
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    • pp.483-491
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    • 2021
  • Purpose: Obesity has become a very significant health problem in childhood. Fructose taken in an uncontrolled manner and consumed in excessive amounts is rapidly metabolized in the body and gets converted into fatty acids. This single center prospective case-control study aims to investigate the relationship between fructose consumption and obesity and the role of fructose consumption in development of atherosclerotic diseases. Methods: A total of 40 obese and 40 healthy children who were of similar ages (between 8 and 18 years) and sexes were included in the study. In the patient and control groups, the urine fructose levels, as well as the levels of oxidized low-density lipoprotein (LDL), small dense LDL, Apolipoprotein A and Apolipoprotein B values, which have been shown to play a role in development of atherosclerotic diseases, were measured. Results: The levels of oxidized LDL and small dense LDL and the ratio of Apolipoprotein A/Apolipoprotein B were found to be significantly higher in the patient group. Conclusion: We found that urinary fructose levels were higher in the obese children than the healthy children. Our results suggest that overconsumption of fructose in children triggers atherogenic diseases by increasing the levels of small dense LDL and oxidized LDL and the ratio of Apolipoprotein B/Apolipoprotein A.

CoMP Transmission for Safeguarding Dense Heterogeneous Networks with Imperfect CSI

  • XU, Yunjia;HUANG, Kaizhi;HU, Xin;ZOU, Yi;CHEN, Yajun;JIANG, Wenyu
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.13 no.1
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    • pp.110-132
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    • 2019
  • To ensure reliable and secure communication in heterogeneous cellular network (HCN) with imperfect channel state information (CSI), we proposed a coordinated multipoint (CoMP) transmission scheme based on dual-threshold optimization, in which only base stations (BSs) with good channel conditions are selected for transmission. First, we present a candidate BSs formation policy to increase access efficiency, which provides a candidate region of serving BSs. Then, we design a CoMP networking strategy to select serving BSs from the set of candidate BSs, which degrades the influence of channel estimation errors and guarantees qualities of communication links. Finally, we analyze the performance of the proposed scheme, and present a dual-threshold optimization model to further support the performance. Numerical results are presented to verify our theoretical analysis, which draw a conclusion that the CoMP transmission scheme can ensure reliable and secure communication in dense HCNs with imperfect CSI.

Simplified Failure Mechanism for the Prediction of Tunnel Crown and Excavation Front Displacements

  • Moghaddam, Rozbeh B.;Kim, Mintae
    • Magazine of korean Tunnelling and Underground Space Association
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    • v.21 no.1
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    • pp.101-112
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    • 2019
  • This case study presented a simplified failure mechanism approach used as a preliminary deformation prediction for the Mexico City's metro system expansion. Because of the Mexico City's difficult subsoils, Line 12 project was considered one of the most challenging projects in Mexico. Mexico City's subsurface conditions can be described as a multilayered stratigraphy changing from soft high plastic clays to dense to very dense cemented sands. The Line 12 trajectory crossed all three main geotechnical Zones in Mexico City. Starting from to west of the City, Line 12 was projected to pass through very dense cemented sands corresponding to the Foothills zone changing to the Transition zone and finalizing in the Lake zone. Due to the change in the subsurface conditions, different constructions methods were implemented including the use of TBM (Tunnel Boring Machine), the NATM (New Austrian Tunneling Method), and cut-and-cover using braced Diaphragm walls for the underground section of the project. Preliminary crown and excavation front deformations were determined using a simplified failure mechanism prior to performing finite element modeling and analysis. Results showed corresponding deformations for the crown and the excavation front to be 3.5cm (1.4in) and 6cm (2.4in), respectively. Considering the complexity of Mexico City's difficult subsoil formation, construction method selection becomes a challenge to overcome. The use of a preliminary results in order to have a notion of possible deformations prior to advanced modeling and analysis could be beneficial and helpful to select possible construction procedures.

Dense Thermal 3D Point Cloud Generation of Building Envelope by Drone-based Photogrammetry

  • Jo, Hyeon Jeong;Jang, Yeong Jae;Lee, Jae Wang;Oh, Jae Hong
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.39 no.2
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    • pp.73-79
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    • 2021
  • Recently there are growing interests on the energy conservation and emission reduction. In the fields of architecture and civil engineering, the energy monitoring of structures is required to response the energy issues. In perspective of thermal monitoring, thermal images gains popularity for their rich visual information. With the rapid development of the drone platform, aerial thermal images acquired using drone can be used to monitor not only a part of structure, but wider coverage. In addition, the stereo photogrammetric process is expected to generate 3D point cloud with thermal information. However thermal images show very poor in resolution with narrow field of view that limit the use of drone-based thermal photogrammety. In the study, we aimed to generate 3D thermal point cloud using visible and thermal images. The visible images show high spatial resolution being able to generate precise and dense point clouds. Then we extract thermal information from thermal images to assign them onto the point clouds by precisely establishing photogrammetric collinearity between the point clouds and thermal images. From the experiment, we successfully generate dense 3D thermal point cloud showing 3D thermal distribution over the building structure.

Study on the Surface Defect Classification of Al 6061 Extruded Material By Using CNN-Based Algorithms (CNN을 이용한 Al 6061 압출재의 표면 결함 분류 연구)

  • Kim, S.B.;Lee, K.A.
    • Transactions of Materials Processing
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    • v.31 no.4
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    • pp.229-239
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    • 2022
  • Convolution Neural Network(CNN) is a class of deep learning algorithms and can be used for image analysis. In particular, it has excellent performance in finding the pattern of images. Therefore, CNN is commonly applied for recognizing, learning and classifying images. In this study, the surface defect classification performance of Al 6061 extruded material using CNN-based algorithms were compared and evaluated. First, the data collection criteria were suggested and a total of 2,024 datasets were prepared. And they were randomly classified into 1,417 learning data and 607 evaluation data. After that, the size and quality of the training data set were improved using data augmentation techniques to increase the performance of deep learning. The CNN-based algorithms used in this study were VGGNet-16, VGGNet-19, ResNet-50 and DenseNet-121. The evaluation of the defect classification performance was made by comparing the accuracy, loss, and learning speed using verification data. The DenseNet-121 algorithm showed better performance than other algorithms with an accuracy of 99.13% and a loss value of 0.037. This was due to the structural characteristics of the DenseNet model, and the information loss was reduced by acquiring information from all previous layers for image identification in this algorithm. Based on the above results, the possibility of machine vision application of CNN-based model for the surface defect classification of Al extruded materials was also discussed.

TSDnet: Three-scale Dense Network for Infrared and Visible Image Fusion (TSDnet: 적외선과 가시광선 이미지 융합을 위한 규모-3 밀도망)

  • Zhang, Yingmei;Lee, Hyo Jong
    • Proceedings of the Korea Information Processing Society Conference
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    • 2022.11a
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    • pp.656-658
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    • 2022
  • The purpose of infrared and visible image fusion is to integrate images of different modes with different details into a result image with rich information, which is convenient for high-level computer vision task. Considering many deep networks only work in a single scale, this paper proposes a novel image fusion based on three-scale dense network to preserve the content and key target features from the input images in the fused image. It comprises an encoder, a three-scale block, a fused strategy and a decoder, which can capture incredibly rich background details and prominent target details. The encoder is used to extract three-scale dense features from the source images for the initial image fusion. Then, a fusion strategy called l1-norm to fuse features of different scales. Finally, the fused image is reconstructed by decoding network. Compared with the existing methods, the proposed method can achieve state-of-the-art fusion performance in subjective observation.

Selective Radiotherapy after Distant Metastasis of Nasopharyngeal Carcinoma Treated with Dose-Dense Cisplatin plus Fluorouracil

  • Liang, Yong;Bu, Jun-Guo;Cheng, Jin-ling;Gao, Wei-Wei;Xu, Yao-Can;Feng, Jian;Chen, Bo-Yu;Liang, Wei-Chao;Chen, Ke-Quan
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.14
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    • pp.6011-6017
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    • 2015
  • Purpose: To investigate the efficacy and safety of selective radiotherapy after distant metastasis of nasopharyngeal carcinoma (NPC) treated with dose-dense cisplatin plus fluorouracil. Materials and Methods: Eligible patients were randomly assigned to a study group treated with dose-dense cisplatin plus fluorouracil following selective radiotherapy and a control group receiving traditional cisplatin plus fluorouracil following selective radiotherapy according to a 1:1 distribution using a digital random table method. The primary endpoint was overall survival (OS). Secondary endpoints were progression-free survival (PFS), objective response rate, relapse or progression rate in the radiation field and treatment toxicity. Results: Of 52 patients in the study group, 20 cases underwent radiotherapy., while in the control group of 51 patients, 16 underwent radiotherapy. The median PFS, median OS, survival rates in 1, 2 and 3 years in study and control group were 20.9 vs 12.7months, 28.3 vs 18.8months, 85.2%vs 65.9%, 62.2% vs 18.3%, and 36.6%vs 5.2% (p values of 0.00, 0.00, 0.04, 0.00 and 0.00, respectively). Subgroup analysis showed that the median OS and survival rates of 1, 2, 3 years for patients undergoing radiotherapy in the study group better than that in control group( 43.2vs24.1 months, 94.1% vs 86.7%, 82.4% vs 43.3%, 64.7% vs 17.3%, (p=0.00, 0.57, 0.04 and 0.01, respectively). The complete response rate, objective response rate after chemotherapy and three months after radiotherapy, relapse or progression rate in radiation field in study group and in control group were 19.2% vs 3.9%, 86.5% vs 56.9%, 85% vs 50%, 95% vs 81.3% and 41.3% vs 66.7% (p =0.03, 0.00, 0.03,0.30, 0.01 respectively). The grade 3-4 acute adverse reactions in the study group were significantly higher than in the control group (53.8% vs 9.8%, p=0.00). Conclusions: The survival of patients benefits from selective radiotherapy after distant metastasis of NPC treated with dose-dense cisplatin plus fluorouracil.

Morphological Characteristics and Occurrence of Yellow Tuft on Zoysiagrass (Zoysia japonica) in Cultivation Fields (들잔디 재배지에 발생한 총생 증상 및 형태적 특성)

  • Cheon, Chang Wook;Han, Jung Ji;Kim, Dong Soo;Kwak, Youn-Sig;Bae, Enu Ji
    • Weed & Turfgrass Science
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    • v.5 no.1
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    • pp.17-22
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    • 2016
  • Yellow tuft symptoms of a dense cluster on zoysiagrass (Zoysia japonica Steud.) occurred extensively at cultivated fields of zoysiagrass sods in Jangsung. The dense cluster of zoysiagrass showed significant morphological changes such as the tufts of shortening of internodes. The disease symptom was spread on a large scale throughout stolon nodes with multiple short leaves and it thrives in broom-like shaped clusters, exhibiting light green or yellow color on their leaves. The dense cluster of zoysiagrass had approximately 5.8 times more leaves on each node of its stolon then healthy zoysiagrass. Also, these zoysiagrass had poorly developed root and stolon caused by the tufts of a dense cluster of shoots. The dense cluster of zoysiagrass were collected for the putative causal agent incubation and upon close observation, it was found that the sporangia took the shape of a lemon, each sporangium was pointed at the end of its axis and was measured to be $60{\sim}96{\times}42{\sim}51{\mu}m$. These findings were analogous to the mycological characteristics of sporangia formed by the pathogen Sclerophthora macrospora. The symptoms of yellow tuft were prevalent in spring and autumn. Therefore, this study aims to present fundamental data in relation to yellow tuft on zoysiagrass in Korea.