• The Bulletin of The Korean Astronomical Society
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• v.36 no.2
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• pp.113.2-113.2
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• 2011

We observed a low-mass pre-main sequence star, HBC722 (also known as $LkH{\alpha}$ 188 G4), with Camera for QUasars in EArly uNiverse (CQUEAN) attached to 2.1 Otto Struve telescope at McDonald Observatory, USA. HBC722 is a new FU orionis-type object in the direction of NGC7000/IC5070, which produced large amplitude optical outbursts (${\delta}V$=4.7 mag over one year) for a few months and reached the peak in 2010 September. We carried out the photometric observation in SDSS r,i, and z band in 2011 April, July and August to monitor the long term decrease of its brightness. We also made continuous observation in r-band for half night in July, and whole two nights in August to investigate short term variability which could be related to the rotation of the central star or the inner circumstellar disk. In this poster, we present a preliminary result of the photometric observation for HBC722.

• YAKHAK HOEJI
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• v.45 no.6
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• pp.650-655
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• 2001

Carvedilol is a nonselective $\beta$-blocking agent with vasodilating properties that are attributed mainly to its blocking activity at $\alpha$$^{1}$-receptors. Carvedilol is used in the treatment of mild to moderate hypertention and angina pectoris and is often used in combination with other drugs. This study was carried out to evaluate the bioequivalence and pharmacokinetics of two carvedilol 25mg tablet formulations according to the guidelines of Korea Food and Drug Administration (KFDA). Twenty healthy volunteers are enrolled and received a single dose (25mg as carvedilol) of each drug in the fasting state, in a randomized 2-way crossover design. After oral administration, blond samples were collected for a period of 30 hours. Plasma concentrations of carvedilol were determined by a rapid and sensitive HPLC method with spectrofluorometric detection. The major pharmacokinetic parameters such as AU $C_{0-}$30hr/, AU $C_{inf}$ , $C_{max}$, $T_{max}$, $t_{1}$2 / Cl/F and V $_{\beta}$//F were calculated. ANOVA test and t-test were utilized for the statistical analysis of each parameter. The results showed that the differences in AU $C_{0-}$30hr/, $C_{max}$ and $T_{max}$ between two were ~5.66, 1.74 and 0.00%, respectively. Minimum detectable differences ($\Delta$) at $\alpha$=0.05 were less than$\pm$ 20% except $T_{max}$ (8.44, 18.36, and 33.86%, respectively). The 90% confidence intervals of all parameters were within $\pm$20% (-10.60~ -0.72, -9.00~12.49 and -19.81~19.81%, respectively). Therefore, it is concluded that the two formulations are bioequivalent for both the extent and the rate of absorption after single dose administration.ation.ion.ion.ation.ion.n.

• Journal of Auto-vehicle Safety Association
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• v.8 no.3
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• pp.10-15
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• 2016

The purpose of this study is to evaluate the injury mechanism of facial injury related to an air-bag's deployment in occupant motor vehicle accident (MVA) by using Hospital Information System (HIS) and reconstruction program, based on the materials related to motor vehicle accidents. Among patients who visited the emergency department of Wonju Severance Christian Hospital due to motor vehicle accidents from August 2012 to February 2014, we collected data on patients with agreement for taking the damaged vehicle's photos. After obtaining the verbal consent from the patient, we asked about the cause of the accident, information on vehicle involved in the accident, and the location of car repair shop. The photos of the damaged vehicle were taken on the basis of front, rear, left side and right side. Damage to the vehicle was presented using the CDC code by analytical study of photo-images of the damaged vehicle, and a trauma score was used for medical examination of the severity of the patient's injury. Among the 309 patients with agreement for an investigation, thirty five (11.3 %) were the severe who had ISS over 15. And also, sixteen (5.2%) derived from the reconstructed data (maximum collision energy, maximum acceleration, delta V) by PC-Crash. As a result, ISS including the facial injuries was affected by the condition. It was high when the number of crash extent, the safety belt was not fastened, and the seating position of occupant and the direction of collision is same. For accurate analysis of the relationship between occupant injury and vehicle damage in MVAs, build-up of an in-depth database through carrying out various policies for motor vehicle accidents is necessary for sure.

• Korean Journal of Materials Research
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• v.18 no.5
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• pp.235-240
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• 2008

This paper presents results and observations obtained from a study of the optical and thermal properties of alkali tellurite depending on the composition. Fourier transform infrared (FT-IR) spectra showed evidence of chemical modification from $TeO_4$ trigonal bipyramids (tbp) to $TeO_3$ trigonal pyramids (tp) in tellurite glasses. The optical band gaps of the different glass samples calculated using Tauc's method were found to range from 3.5-3.8 eV. The glass transition temperature (Tg) and glass stability (${\Delta}T$) of alkali tellurite glasses were investigated, as $M_2O$ [M: Li, Na, K] amounted to 25 mol%, through the use of differential thermal analysis (DTA). The coefficient of thermal expansion (CTE) was measured in a thermo mechanical analysis (TMA) with a slow heating rate after the glass samples were annealed. The results confirm that the optical band gap of alkali tellurite glasses depends on the Te-O-Te structural relaxation related to the ratio of bridging/non bridging oxygen (BO/NBO). In contrast, the thermal properties are related to the ionic field strength of the Te-O-M and M-O-M bonds, and the Te-O-Te breakage depends on the ratio of BO/NBO.

• Proceedings of the KIEE Conference
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• 1994.07b
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• pp.1277-1279
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• 1994

In the structure of ZnO/nip-SiC: H/metal substrate amorphous silicon (a-Si:H) solar cells, the effects of inserting a rear textured ZnO in the p-SiC:H/metal interface and a graded bandgap buffer layer in the i/p-SiC:H have been analysed by computer simulation. The incident light was taken to have an intensity of $100mW/cm^2$(AM-1). The thickness of the a-Si:H n, ${\delta}$-doped a-SiC:H p, and buffer layers was assumed to be $200{\AA},\;66{\AA}$, and $80{\AA}$, respectively. The scattering coefficients of the front and back ZnO were taken to be 0.2 and 0.7, respectively. Inserting the rear buffer layer significantly increases the open circuit voltage($V_{oc}$) due to reduction of the i/p interface recombination rate. The use of textured ZnO markedly improves collection efficiency in the long wavelengths( above ${\sim}550nm$ ) by back scattering and light confinement effects, resulting in dramatic enhancement of the short circuit current density($J_{sc}$). By using the rear buffer and textured ZnO, the i-layer thickness of the ceil for obtaining the maximum efficiency becomes thinner(${\sim}2500{\AA}$). From these results, it is concluded that the use of textured ZnO and buffer layer at the backside of the ceil is very effective for enhancing the conversion efficiency and reducing the degradation of a-Si:H pin-type solar cells.

• Proceedings of the Korean Biophysical Society Conference
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• 2003.06a
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• pp.47-47
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• 2003

The presenilin 1 (PS1) or PS2 is an essential component of the ${\gamma}$-secretase complex, which mediates the intramembrane proteolysis of selected type-I membrane, including the ${\beta}$-amyloid precursor protein (APP) to yield A${\beta}$. Familial Alzheimer's disease (FAD)-associated mutations in presenilins give rise to an increased production of a highly amyloidogenic A${\beta}$42. In addition to their well-documented proteolytic function, the presenilins play a role in calcium signaling. We have previously reported that presenilin FAD mutations cause highly consistent alterations in intracellular calcium signaling pathways, which include deficits in capacitative calcium entry (CCE), the refilling mechanism for depleted internal calcium stores. However, molecular basis for the presenilin-mediated modulation of CCE remains to be elucidated. In the present study, whole-cell patch clamp method was used to identify a specific calcium-permeable ion channel current(s) that is responsible for the CCE deficits associated with FAD-linked PS1 mutants. Unexpectedly, both voltage-activated and conventional store depletion-activated calcium currents I(CRAC), were absent in HEK293 cells, which were stably transfected either with wild-type or FAD mutant (L286V, M146L, and delta E9) forms of PS1. Recently, magnesium-nucleotide-regulated metal cation current, or I(MagNum), has been described and appears to share many common properties with I(CRAC) including calcium permeability and inhibitor sensitivity (e.g. 2-APB). We have detected I(MagNum) in all 293 cells tested. Interestingly, FAD mutant 293 cells developed only about half of currents compared to PS1 wild type cells.

• The Bulletin of The Korean Astronomical Society
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• v.38 no.1
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• pp.43.2-43.2
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• 2013

The local environmental effects on the triggering of active galactic nucleus(AGN) activity has been studied with many authors, but there still be controversy. We perform statistical analysis for nearby(0.01 < z < 0.05) volume limited(Mr < -19) samples with visual inspection based on Sloan Digital Sky Survey Data Release7. We inspect ~60,000 galaxy images visually to find peculiar objects which show not only ongoing merging features and tidal features, but also post merging features like ring or shell structures. We found that these peculiar features were shown at least 2 times more frequently among AGN host galaxies than non AGN galaxies, and this trend was still visible when galaxy properties such as color or stellar mass are fixed. Furthermore, L[OIII] and L(Ha) of peculiar galaxies are found to be more increased than those of normal galaxies. In order to ensure this results, we also checked it for a smaller subsample with ~2mag deeper monochromatic images provided from SDSS Stripe82 database, and found consistent results. At last, we perform the same work for pair(r_p<80kpc/h, delta_v<200km/s) systems. Because of some pair systems which do not interact gravitationally in actuality but fulfill the criteria for identification of pair system, the trends are found to be slightly weaker. We also found that line luminosities are increased consistently as projected distance between central and companion galaxy decreased, and as companion color gets bluer. Overall, the results of this study tell us that the local environment of galaxies affect the frequency as well as the strength of AGN activity. Local environmental effects, however, may not be the dominant triggering mechanism for AGN activity since the majority of peculiar galaxies are non AGN galaxies.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.28 no.3C
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• pp.239-247
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• 2003

This paper presents a dual-rate (2.4/4.0 kbps) Improved Harmonic-CELP(IHC) speech coder based on the EHC(Efficient Harmonic-CELP) which was presented by the authors. The proposed IHC employs the harmonic coding for voiced and the CELP for unvoiced segments. In the IHC, an initial voiced/unvoiced estimate is obtained by the pitch gain and energy. Then, the final V/UV mode is decided by using the frame energy contour. A new harmonic estimation combining peak picking and delta adjustment provides a more reliable harmonic estimation than that in the EHC. In addition, a noise mixing scheme in conjunction with an improved band voicing measurement provides the naturalness of the synthesized speech. To demonstrate the performance of the proposed IHC coder, the coder has been implemented and compared with the 2.0/4.0 kbps HVXC(Harmonic excitation Vector Coding) standardized by MPEG-4. Results of subjective evaluation showed that the proposed IHC coder and produce better speech quality than the HVXC, with only 40% complexity of the HVXC.

• Journal of the Korea Society of Computer and Information
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• v.15 no.5
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• pp.13-21
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• 2010

The Optimal results of Kalman Filtering on the Inverted Pendulum System requires an effective factor such as the noise covariance matrix Q, the measurement noise covariance matrix R and the initial error covariance matrix $P_0$. We present a special case where the optimality of the filter is not destroyed and not sensitive to scaling of these covariance matrix because these factors are unknown or are known only approximately in the practical situation. Moreover, the error covariance matrices issued by this method predict errors in the state estimate consistent with the scaled covariance matrices and not the issued state estimates. Various results using the scalar gain $\delta$ are derived to described the relations among the three covariance matrices, Kalman Gain and the error covariance matrices. This paper is described as follows: Section III a brief overview of the Inverted Pendulum system. Section IV deals with the mathematical dynamic model of the system used for the computer simulation. Section V presents a various simulation results using the scalar gain.

• Publications of The Korean Astronomical Society
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• v.30 no.2
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• pp.565-568
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• 2015

In this work, we study the correlation between the photon index (${\Gamma}$) of the X-ray spectrum and the 2-10 keV X-ray luminosity ($L_X$) for black hole X-ray binaries (BHBs). The BHB sample is mainly from the quiescent, hard and intermediate states, with values of $L_X$ ranging from ${\sim}10^{30.5}$ to $10^{37.5}$ erg $s^{-1}$. We find that the photon index ${\Gamma}$ is positively or negatively correlated with the X-ray luminosity $L_X$, for $L_X$ above or below a critical value, ${\sim}10^{36.5}$ erg $s^{-1}$. This result is consistent with previous works. Moreover, when $L_X{\leq}{\sim}10^{33}$ erg $s^{-1}$, we found that the photon index is roughly independent of the X-ray luminosity. We interpret the above correlations in the framework of a coupled hot accretion flow - jet model. Besides, we also find that in the moderate-luminosity region, different sources may have different anti-correlation slopes, and we argue this diversity is caused by the different value of ${\delta}$, which describes the fraction of turbulent dissipation that directly heats electrons.