• 대한조선학회지
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• 제13권1호
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• pp.1-9
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• 1976

Using the computer programs for calculation of natural vibrations of ship's hull developed by the authors et al., an investigation into influences of various parameters on the accuracy of calculation was done through example calculations of a 30,000 DWT petroleum products carrier M/S Sweet Brier built by Korea Shipbuilding and Engineering Corporation. The methodical principles employed for the computer program development are as follows; (a) the ship system is reduced to an equivalent discrete elements system conforming to Myklestad-Prohl model, (b) the problem formulation is of transfer matrix method, and (c) to obtain solutions an extended $G\ddot{u}mbel's$ initial value method is introduced. The scope of the investigation is influences of number of discrete elements, choice of significant system parameters such as rotary inertia, bending stiffness and shear stiffness, and simplification of distributions of added mass and stiffness as trapezoidal ones referred to those of midship section on the calculation accuracy. From the investigation the followings are found out; (1) To obtain good results for the modes up to the seven-noded thirty or more divisions of the hull is desirable. For fundamental mode fifteen divisions may give fairly good results. (2) The influence of rotary inertia is negligibly small at least for the modes up to the 5- or 6- noded. (3) In the case of assuming either bending modes or shear modes the calculation results in considerably higher frequencies as compared with those based on Timoshenko beam theory. However, the calculation base on the slender beam theory surprisingly gives frequencies within 10% error for fundamental modes. (4) It is proved that to simplify distributions of added mass and stiffness as trapezoidal ones referred to those of midship section is a promising approach for the prediction of natural frequencies at preliminary design stage; provided good accumulation of data from similar type ships, we may expect to obtain natural frequencies within 5% error.

• 한국ITS학회 논문지
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• 제16권4호
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• pp.64-75
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• 2017

기존의 고정모수를 이용한 가산모형은 관측되지 않은 이질성을 고려할 수 없으며, 계수값의 표준오차가 과소추정됨에 따라 과도한 t-값이 도출되어 모형의 신뢰성이 감소하게 된다. 또한 무신호교차로의 경우 자료 수집의 어려움과 정확한 분석과정의 통계적 한계로 신호교차로에 비해 연구가 미비한 실정이다. 본 연구에서는 Random Parameter를 이용한 가산모형을 구축하여 교통사고에 영향을 미치는 요인들을 분석하고자 하였으며, 지방부 무신호교차로를 대상으로 하여 기존 연구들과의 차별성을 두고자 하였다. 분석 결과, 총 7개의 변수가 유의한 변수로 나타났고, 이 중 2개의 변수(횡단보도 유무, 제한 속도)가 확률적 변수로 나타났다.

• 한국안전학회지
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• 제27권3호
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• pp.36-41
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• 2012

Electrical Connections often cause fires due to poor contact. Occurrence rate of these fires tends to increase annually. The reason why poor contacts occur is often because it is the low mechanical pressure at the contact points. A typical connection method using mechanical pressure is a screw terminal type. This study reviewed these poor contact cases in the screw terminals. In order to get reproduction of such cases, two types of experiments were conducted. the first one was conducted under the normal contact condition, and the other one was conducted under the poor contact condition that screw terminal of breaker was loosen and did not meet the requirements of toque value. In both types of experiments, compulsory vibration was adopted as a variable to aggravate poor contacts. Each of various current values(4.5A, 9.0A, 13.5A) is input. In these experiments, relationships of a contact, electrical signal such as current and electric pulse by ZCT and thermal characteristics according to vibration effect are analyzed. The suggested data and results in this study provide the useful resources helping to investigate fires due to poor contact, and they develop the detector for poor contact and finally reduce the electrical fire occurrence rate.

• Genomics & Informatics
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• 제12권4호
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• pp.268-275
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• 2014

The harshness of legionellosis differs from mild Pontiac fever to potentially fatal Legionnaire's disease. The increasing development of drug resistance against legionellosis has led to explore new novel drug targets. It has been found that phosphoglucosamine mutase, phosphomannomutase, and phosphoglyceromutase enzymes can be used as the most probable therapeutic drug targets through extensive data mining. Phosphoglucosamine mutase is involved in amino sugar and nucleotide sugar metabolism. The purpose of this study was to predict the potential target of that specific drug. For this, the 3D structure of phosphoglucosamine mutase of Legionella pneumophila (strain Paris) was determined by means of homology modeling through Phyre2 and refined by ModRefiner. Then, the designed model was evaluated with a structure validation program, for instance, PROCHECK, ERRAT, Verify3D, and QMEAN, for further structural analysis. Secondary structural features were determined through self-optimized prediction method with alignment (SOPMA) and interacting networks by STRING. Consequently, we performed molecular docking studies. The analytical result of PROCHECK showed that 95.0% of the residues are in the most favored region, 4.50% are in the additional allowed region and 0.50% are in the generously allowed region of the Ramachandran plot. Verify3D graph value indicates a score of 0.71 and 89.791, 1.11 for ERRAT and QMEAN respectively. Arg419, Thr414, Ser412, and Thr9 were found to dock the substrate for the most favorable binding of S-mercaptocysteine. However, these findings from this current study will pave the way for further extensive investigation of this enzyme in wet lab experiments and in that way assist drug design against legionellosis.

• Structural Engineering and Mechanics
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• 제22권2호
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• pp.197-222
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• 2006

In this paper, the non-linear time-dependent closed-form, discrete and combined solutions for the post-elastic response of a geometrically and physically non-linear suspended cable to a uniformly distributed load considering the creep effects, are presented. The time-dependent closed-form method for the particularly straightforward determination of a vertical uniformly distributed load applied over the entire span of a cable and the accompanying deflection at time t corresponding to the elastic limit and/or to the elastic region, post-elastic and failure range of a suspended cable is described. The actual stress-strain properties of steel cables as well as creep of cables and their rheological characteristics are considered. In this solution, applying the Irvine's theory, the direct use of experimental data, such as the actual stress-strain and strain-time properties of high-strength steel cables, is implemented. The results obtained by the closed-form solution, i.e., a load corresponding to the elastic limit, post-elastic and failure range at time t, enable the direct use in the discrete non-linear time-dependent post-elastic analysis of a suspended cable. This initial value of load is necessary for the non-linear time-dependent elastic and post-elastic discrete analysis, concerning incremental and iterative solution strategies with tangent modulus concept. At each time step, the suspended cable is analyzed under the applied load and imposed deformations originated due to creep. This combined time-dependent approach, based on the closed-form solution and on the FEM, allows a prediction of the required load that occurs in the post-elastic region. The application of the described methods and derived equations is illustrated by numerical examples.

• Geomechanics and Engineering
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• 제10권6호
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• pp.757-774
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• 2016

Soils are usually weak in tension therefore different materials such as geosynthetics are used to address this inadequacy. Worldwide annual consumption of geosynthetics is close to $1000million\;m^2$, and the value of these materials is probably close to US$1500 million. Since the total cost of the construction is at least four or five times the cost of the geosynthetic itself, the impact of these materials on civil engineering construction is very large indeed. Nevertheless, there are several significant problems associated with geosynthetics, such as creep, low modulus of elasticity, and susceptibility to aggressive environment. Carbon fiber reinforced polymer (CFRP) was introduced over two decades ago in the field of structural engineering that can also be used in geotechnical engineering. CFRP has all the benefits associated with geosynthetics and it boasts higher strength, higher modulus, no significant creep and reliability in aggressive environments. In this paper, the performance of a CFRP reinforced retaining wall is investigated using the finite element method. Since the characterization of behavior of soils and interfaces are vital for reliable prediction from the numerical model, soil and interface properties are obtained from comprehensive laboratory tests. Based on the laboratory results for CFRP, backfill soil, and interface data, the finite element model is used to study the behavior of a CFRP reinforced wall. The finite element model was verified based on the results of filed measurements for a reference wall. Then the reference wall simulated by CFRP reinforcements and the results. The results of this investigations showed that the safety factor of CFRP reinforced wall is more and its deformations is less than those for a retaining wall reinforced with ordinary geosynthetics while their construction costs are in similar range.

• 한국자기학회지
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• 제23권4호
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• pp.130-134
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• 2013

자성센싱 홀소자가 구비된 집게형 맥진기와 대중적인 생체신호를 측정하는 심전도를 이용하여 맥파전달속도(PWV)를 조사하였다. 동시 측정된 심전도파의 피크치와 요골동맥파의 시작점의 시간차 그리고 심장과 손목간의 거리차를 가지고 맥파전달속도를 계산하였다. 임상데이터로부터 분석된 PWV값은 5~7 m/s의 범위 안에 평균 6 m/s이었다. 맥파전달속도 분석을 통한 혈관탄성도를 예측함으로써, 미래의 한양방 협진용 건강관리 의료기기에서 제시하는 주요 지수로 응용할 수 있는 가능성을 확인하였다.

• 한국수자원학회논문집
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• 제43권4호
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• pp.337-351
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• 2010

극치사상을 예측하기 위한 기존의 빈도분석 결과의 이용에 대한 많은 문제점들이 부각되고 있다. 특히, 통계적 모형을 이용하기 위해서 흔히 사용되는 점근적 모형 (asymptotic model)의 합리적인 검토 없는 외삽 (extrapolation)은 산정된 확률 값을 과대 또는 과소평가하는 문제를 일으켜, 예측결과에 대한 불확실성을 과다하게 산정함으로써 불확실성에 대한 신뢰도를 감소시키는 문제가 있다. 그러므로 본 연구에서는 국내에서 극치강우사상을 포함한 강우자료의 빈도분석에 대한 연구사례를 제공하고 점근적 모형을 사용하는 경우 발생되는 불확실성을 감소시키기 위한 방법론을 제시하였다. 이를 위하여 본 연구에서는 극치강우사상의 빈도분석을 수행하는 데 있어서 최근 들어 여러 분야에서 다양하게 적용되고 있는 Bayesian MCMC (Markov Chain Monte Carlo) 방법을 사용하였으며, 그 결과를 최우추정방법 (Maximum likelihood estimation method)과 비교하였다. 특히 강우사상의 점 빈도분석에 흔히 이용되는 확률밀도함수로 GEV (Generalized Extreme Value) 분포와 Gumbel 분포를 모두 고려하여 두 분포의 결과를 비교하였으며, 이 과정에서 각각의 산정결과 및 불확실성은 근사식을 이용한 최우추정방법과 Bayesian 방법을 이용하여 각각 비교 및 분석되었다.

• Journal of Korean Neurosurgical Society
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• 제60권5호
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• pp.504-510
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• 2017

Objective : To investigate the morphological and hemodynamic parameters associated with middle cerebral artery (MCA) bifurcation aneurysm rupture. Methods : A retrospective study of 67 consecutive patients was carried out based on 3D digital subtraction angiography data. Morphological and hemodynamic parameters including aneurysm size parameters (dome width, height, and perpendicular height), longest dimension from the aneurysm neck to the dome tip, neck width, aneurysm area, aspect ratio, Longest dimension from the aneurysm neck to the dome tip (Dmax) to dome width, and height-width, Bottleneck factor, as well as wall shear stress (WSS), low WSS area (LSA), percentage of LSA (LSA%) and energy loss (EL) were estimated. Parameters between ruptured and un-ruptured groups were analyzed. Receiver operating characteristics were generated to check prediction performance of all significant variables. Results : Sixty-seven patients with MCA bifurcation aneurysm were included (31 unruptured, 36 ruptured). Dmax (p=0.008) was greater in ruptured group than that in un-ruptured group. D/W (p<0.001) and the percentage of the low WSS area ($0.09{\pm}0.13$ vs. $0.01{\pm}0.03$, p<0.001) were also greater in the ruptured group. Moreover, the EL in ruptured group was higher than that in unruptured group ($6.39{\pm}5.04$ vs. $1.53{\pm}0.86$, p<0.001). Multivariate regression analysis suggested D/W and EL were significant predictors of rupture of MCA bifurcation aneurysms. Correlation analyses revealed the D/W value was positively associated with the EL (R=0.442, p<0.01). Conclusion : D/W and EL might be the most two favorable factors to predict rupture risk of MCA bifurcation aneurysms.

• 한국지능시스템학회논문지
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• 제19권5호
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• pp.730-736
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• 2009

방대한 유전 정보를 분석, 가공하는 생명정보학의 중요성은 더욱 높아지고 있다. 본 논문에서는 단백질의 1차 구조만으로 단백질의 구조와 기능을 예측하는 새로운 데이터마이닝 방법을 제안한다. 단백질 서열만으로 특징 추출시 발생할 수 있는 문제점인 방대한 탐색공간을 효과적으로 축소하기 위해 n-Block substring 탐색 알고리즘을 제안한다. 또한 선별된 각 substring의 도메인 연관도를 결정하는 가중치를 구하여 가중 선형모형을 구축함으로써 구조와 기능에 관련이 있을 것으로 예상되는 단백질 도메인의 특징을 추출하고 분류에 효과적임을 보인다. 도메인에 포함되는 각각의 CDS(coding sequence)에 대해 모형으로부터 구한 점수를 통해 해당 도메인과의 연관성의 정도를 추정하며, 분류 효율을 더욱 향상시킬 수 있음을 보인다.