• 한국건설관리학회:학술대회논문집
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• 한국건설관리학회 2004년도 제5회 정기학술발표대회 논문집
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• pp.608-611
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• 2004

건설 프로세스에서 효율성은 프로젝트의 성패를 좌우하는 중요한 요인 중의 하나이다. 하지만 기존의 생산성 향상 방안들은 1인당 매출과 같이 단순히 결과 위주의 지표를 중심으로 프로젝트를 관리함으로써 많은 변화 요인을 가지고 있는 건설 산업을 특성을 반영하는데 한계를 가지고 있으며, 특히 다수의 참여자에 의해 여러 단계로 진행되는 건설 프로젝트의 Life cycle 상에서 각 공종별 생산성 측정 및 관리, 그리고 생산성 저하의 원인을 도출하는데 한계를 가지고 있다. 따라서 본 연구는 결과 위주의 성과측정 방법인 생산성 개념을 보완하기 위해 프로젝트의 Life cycle의 각 단계별 정성적 평가를 포함하는 건설 효율성 개념을 제안하고 이를 측정하는 방법론을 제시하였으며, 초고층 빌딩의 커튼월 프로세스를 대상으로 제안한 모델을 적용하져다.

• 한국유체기계학회 논문집
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• 제20권1호
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• pp.41-47
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• 2017

This study aimed to analyze organic Rankine cycle(ORC) which recovers discarded heat from a gas turbine based combined cycle cogeneration(CC-cogen) plant in terms of both performance and economics. The nominal electric power of the CC-cogen plant is around $120MW_e$, and heat for district heating is $153MW_{th}$. The major purpose of this study is to compare various options in selecting heat source of the ORC. Three heat sources were compared. Case 1 uses the exhaust gas from the HRSG, which is purely wasted to environment in normal plant operation without ORC. Case 2 also uses the exhaust gas from the HRSG. On the other hand, in this case, the DH economizer, which is located at the end of the HRSG, does not operate. Case 3 generates power using some of the district heating water which is supplied to consumers. The estimated ORC power generation ranges between 0.3 to 2.3% of the power generation capacity of the CC-cogen plant. Overall, Case 3 is evaluated to be better than other two options in terms of system design flexibility and power generation capacity.

• Corrosion Science and Technology
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• 제3권4호
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• pp.166-171
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• 2004

Recent developments in Bridge Management Systems (BMS) and in Life-Cycle Cost (LCC) of bridges, have raised the need for evaluation procedure of future condition (Deterioration) of a bridge. Predicting future deterioration is not an easy task due to limited past data to extrapolate from and also due to difficulty in measuring actual deterioration such as section loss of steel on an actual steel bridge. Also, increase in live load and reduction of resistance are random variables, thus a probabilistic approach should be adopted for determining the future deterioration. Due to difficulties in evaluation of future deterioration on steel bridges, accepting uncertainties within a reasonable error, a deterministic procedure using bridge condition rating can be a useful tool for projection of future condition of bridges to identify repair and maintenance needs. The object of this paper is to determine applicability of evaluating deterioration of steel bridge components based on Bridge condition ratings. Bridge condition ratings of bridge components show wide variation for bridges of same age and does not directly correlate well with the age of the bridge and/or deterioration of the bridge. High uncertainty can be reduced by breaking down the rating and by sensitivity analysis. From refined condition rating data, generalized deterioration profile of structures based on age can be derived. Examples are shown for sample bridges in USA. Approximately, 3,000 short to medium span steel bridges were listed in the inventory database. Results show wide variation of rating factors but by subdividing the Bridge condition ratings for various categories general deterioration profiles of steel bridges can be determined.

• 인터넷정보학회논문지
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• 제22권6호
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• pp.71-81
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• 2021

본 논문은 미국 등 선진국에서 적용하고 있는 무기체계 전 수명주기 동안에 사이버보안을 향상 시킬수 있는 방안에 대해 현재까지 진행되고 있는 연구에 대해 알아보고, 국내 무기체계 획득시의 제한사항을 분석하여 효과적인 보안평가 방안을 제시하였다. 국내 실정에 맞는 사이버보안 시험평가 방안에 임무 기반의 위험평가를 획득 전 단계에서 일관성있게 수행함으로써 주요 의사결정 조직에 주요한 정보를 적시에 제공하여 의사결정을 지원하고, 사이버보안 측면에서 식별된 취약점에 대해 보호대책을 검증할 수 있도록 교전규칙을 설정하여 모의침투를 수행하는 방안을 제안하였다. 또한 제안하는 사이버보안 시험평가 체계를 국내 무기체계 시험평가와 비교 평가를 수행하였다. 이를 통하여 지금까지 진행된 사이버보안 시험평가체계 연구에 임무 기반의 위험평가 요소를 접목하여 획득 사업간 적시에 위험을 식별하여 주요 의사결정을 지원하는 역량을 보완하였다.

• Steel and Composite Structures
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• 제20권4호
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• pp.913-930
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• 2016

It is common practice to use Reduced Web Beam Sections (RWBS) in steel moment resisting frames. Perforation of beam web in these members may cause stress and strain concentration around the opening area and facilitate ductile fracture under cyclic loading. This paper presents a numerical study on the cyclic fracture of these structural components. The considered connections are configured as T-shaped assemblies with beams of elongated circular perforations. The failure of specimens under Ultra Low Cycle Fatigue (ULCF) condition is simulated using Cyclic Void Growth Model (CVGM) which is a micromechanics based fracture model. In each model, CVGM fracture index is calculated based on the stress and strain time histories and then models with different opening configurations are compared based on the calculated fracture index. In addition to the global models, sub-models with refined mesh are used to evaluate fracture index around the beam to column weldment. Modeling techniques are validated using data from previous experiments. Results show that as the perforation size increases, opening corners experience greater fracture index. This is while as the opening size increases the maximum observed fracture index at the connection welds decreases. However, the initiation of fracture at connection welds occurs at lower drift angles compared to opening corners. Finally, a probabilistic framework is applied to CVGM in order to account for the uncertainties existing in the prediction of ductile fracture and results are discussed.

• Journal of Microbiology and Biotechnology
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• 제32권6호
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• pp.718-729
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• 2022

Esophageal squamous cell carcinoma (ESCC) is the most common primary esophageal malignancy with poor prognosis. Here, due to the necessity for exploring potential therapies against ESCC, we obtained the gene expression data on ESCC from the TCGA and GEO databases. Venn diagram analysis was applied to identify common targets. The protein-protein interaction network was constructed by Cytoscape software, and the hub targets were extracted from the network via cytoHubba. The potential hub nodes as drug targets were found by pharmacophore-based virtual screening and molecular modeling, and the antitumor activity was evaluated through in vitro studies. A total of 364 differentially expressed genes (DEGs) in ESCC were identified. Pathway enrichment analyses suggested that most DEGs were mainly involved in the cell cycle. Three hub targets were retrieved, including CENPF, CCNA2 (cyclin A), and CCNB1 (cyclin B1), which were highly expressed in esophageal cancer and associated with prognosis. Moreover, amentoflavone, a promising drug candidate found by pharmacophore-based virtual screening, showed antiproliferative and proapoptotic effects and induced G1 in esophageal squamous carcinoma cells. Taken together, our findings suggested that amentoflavone could be a potential cell cycle inhibitor targeting cyclin B1, and is therefore expected to serve as a great therapeutic agent for treating esophageal squamous cell carcinoma.

• 한국전산구조공학회:학술대회논문집
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• 한국전산구조공학회 2007년도 정기 학술대회 논문집
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• pp.62-67
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• 2007

The research team for the virtual construction development was established with the support of Korea Ministry of Construction and Transportation, and KICTEP (Korea Institute of Construction and Transportation Technology Evaluation and Planning). Its aims are to develop system that is to improve productivity & quality, to create a higher value-added business, and to cultivate international competitiveness in the construction industry. The virtual construction system is a design, engineering, and construction management information system that allows the project participants to effectively share the information throughout the construction life cycle with the support of 3D and design information. To achieve this, the research team focuses on developing several systems. First, the team focuses on developing for the pre-planning, the structural engineering, MEP, and the 3D based estimation system. Second, they focus on developing a simulation system for the construction process planning and feasibility study with help of the virtual reality technologies. Third, they focus on developing the CPLM (Construction Project Life-cycle Management) system for managing construction project data, and the decision support system that makes the collaboration among the project participants based on 3D technologies and information. We also focus on developing the SDAI (Standard Data Access Interface), the localized guideline for 3D design, and a training program. In addition, we focus on developing the undeveloped area of the commercial system and building an environment that can support the communication and collaboration in the construction life-cycle rather than developing the existing and commercialized system.

• 한국구조물진단유지관리공학회 논문집
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• 제15권5호
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• pp.113-123
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• 2011

LCC 분석은 비용평가만을 위한 개별적인 방법이 아닌 가치 개선을 위해 기능평가와 상호 연계되어 이루어지는 방법이다. 점차 LCC 분석의 정확성은 높아지고 있으나 비교적 최근에 개발 적용되어진 재료나 형식들에서는 공용기간이 확보되지 않아 여전히 유지관리 이력을 추정하기가 어려워 신뢰도가 떨어진다. 이런 배경으로 본 연구는 유지관리 프로파일을 설정하기 어려운 대안들에 대해서 기능적인 증감사항이 비용과 연계되어 분석되어지는 LCC 방법론을 제시하고자 한다. 최근 강상판 교면포장은 중차량과 교통량의 증가로 소성변형 등 문제점이 발생하여 기존의 포장을 대체할 수 있는 새로운 혼합물포장의 개발이 활발히 이루어지고 있다. SMA, Guss 및 PSMA 포장을 사례로 들어 대안 간에 비교된 성능척도가 상대평가계수로써 유지관리 프로파일 항목에 포함되어 LCC 분석이 이루어졌다.

• 한국건설관리학회논문집
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• 제8권2호
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• pp.75-83
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• 2007

최근 국내의 설계시공일괄방식(이하, 일괄방식)은 설계시공분리방식(이하, 기타방식)에 비해 높은 초기투자비용으로 인하여, 효용성에 대한 의문이 지속되고 있다 한편 발주방식별 성능을 평가한 기존의 연구를 살펴보면, 일괄방식은 공기측면과 품질측면에서 기타방식에 비해 우수한 것으로 보고되고 있다. 비교적 정량적 평가가 가능한 공기측면의 성과와 달리, 품질 측면의 성능은 해당 시설물의 발주자와의 면담을 통하여 만족도 수준을 평가하는 정성적인 평가가 대부분이다. 따라서 이 연구에서는 기존의 연구와는 달리, 2000년 이후 일괄방식과 기타방식으로 발주된 교량계획에 대한 성능수준을 평가하기 위하여, 설계도서 중심으로 계획성, 시공성, 유지관리성 등의 측면에서 평가해 보고자 한다. 이를 통하여 실제로 발주방식별 품질 등의 성능 측면에서 발주방식별 성능수준의 차이를 도출하였다.

• 대한기계학회논문집B
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• 제24권12호
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• pp.1625-1634
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• 2000

Verification of measurements is required for precise evaluation of turbine cycle performance in nuclear power plant. We assumed that initial acceptance data and design data of the plant could provide correlation information between performance data. The data can be used as sample sets for the correct estimation model of measurement value. The modeling was done practically by using regression model based on plant design data, plant acceptance data and verified plant performance data of domestic nuclear power plant. We can construct more robust performance analysis system for an operation nuclear power plant with this validation scheme.