• 디지털융복합연구
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• 제13권8호
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• pp.473-481
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• 2015

강 유역의 홍수 및 환경 감시망은 고품질의 영상정보를 고속으로 전달할 수 있는 광통신 장치와 함께 각종 센서로 부터의 정보를 효율적으로 관리할 수 있는 방법이 요구되는 네트워크이다. 특히, 네트워크의 절단이나 노화로 인한 통신장애들은 현장에서의 신속한 복구가 매우 중요하기 때문에 다양한 연구가 진행되고 있다. 그러나, 국가 기간망과 같은 환경 감시망은 외부의 해킹이나 불법적인 목적의 외부침입에 대한 보안이 매우 중요하기 때문에 보안성과 신뢰성을 만족하면서도 효율적인 네트워크 유지보수가 가능하도록 하여야 한다. 이와같은 요구사항은 보안성을 제고하면 유지보수의 효율성이 떨어지는 서로 상충되는 특성을 가지고 있다. 따라서 본 연구에서는 보안성을 제고하기 위해 단방향 Bypass TAP를 개발하고 효율적인 유지보수가 가능하도록 안드로이드기반의 스마트폰용 앱을 개발하여 상반된 요구사항을 충족시킬 수 있도록 하는 시스템을 제안한다. 제안된 시스템은 통신 전송망 및 다양한 시설의 관리망 등 인터넷으로 부터의 침입에 의한 위험등에 대한 보안이 필요한 분야에서 폭넓게 이용될 것으로 판단된다.

• Asian Pacific Journal of Cancer Prevention
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• 제13권2호
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• pp.443-446
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• 2012

Purpose: Telomeres play a key role in the maintenance of chromosome integrity and stability, and telomere shortening is involved in initiation and progression of malignancies. The aim of this study was to determine whether telomere length is associated with the colorectal carcinoma. Patients and methods: A total of 148 colorectal cancer (CRC) samples and corresponding adjacent non-cancerous tissues were evaluated for telomere length, P53 mutation, and cyclooxygenase-2 (COX-2) mutation detected by fluorescent immunohistochemistry. Telomere length was estimated by real-time PCR. Samples with a T/S>1.0 have an average telomere length greater than that of the standard DNA; samples with a T/S<1.0 have an average telomere length shorter than that of the standard DNA. Results: Telomeres were shorter in CRCs than in adjacent tissues, regardless of tumor stage and grade, site, or genetic alterations (P=0.004). Telomere length in CRCs also had differences with COX-2 status (P=0.004), but did not differ with P53 status (P=0.101), tumor progression (P=0.244), gender (P=0.542), and metastasis (P=0.488). There was no clear trend between T/S optimal cut-off values (<1 or > 1) and colorectal tumor progression, metastasis, gender, P53 and COX-2 status. Conclusion: These findings suggesting that telomere shortening is associated with colorectal carcinogenesis but does not differ with tumor progression, gender, and metastasis.

• 한국전기전자재료학회논문지
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• 제30권6호
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• pp.393-400
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• 2017

For comparison to the Li-ion battery, evaluating a thermal battery must consider additional variables. The first one is the temperature difference between the battery and its unit cell. Thermal batteries and their unit cells have a temperature difference that is caused by the thermal battery activation mechanism and its shape. The second variable is the electrochemical reaction steps. Most Li-ion batteries have a constant electrochemical reaction at the electrode, and battery voltage is affected when the concentration of Li ions is changed. However, a thermal battery has several steps in its electrochemical reaction, and each step has a different potential. In this study, we used unit cell discharge tests based on interpolating a 4D lookup table to estimate the performance of a thermal battery. From the test results, we derived an estimation algorithm by interpolating the table, which is queried from specified profile groups. As a result, we found less than a 5 percent difference between estimation and experiment at the 1.3 V cut-off time.

• 한국지반환경공학회 논문집
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• 제5권4호
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• pp.57-63
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• 2004

강널말뚝(sheet pile)은 지하수의 침투저하 및 누수방지를 위하여 토목공사에서 폭넓게 이용되고 있으며, 특히 최근에는 강널말뚝의 지수효과로 인하여 오염된 지역의 지하수 흐름 또는 침출수의 차폐에도 사용되고 있다. 따라서 본 논문에서는 Z형 강널말뚝을 오염지역의 오염물질 차폐방법으로 적용할 경우에 대하여 살펴보았다. 이를 위하여 지수재의 도포조건과 강널말뚝의 시공조건 그리고 지반조건에 따른 Z형 강널말뚝의 연결부에 대한 실내 및 현장실험을 실시하였다. 실험결과, Z형 강널말뚝에 대한 모형실험을 통하여 지반조건에 따른 강널말뚝의 팽창지수재 도포방법, 강널말뚝 설치방법, 지반조건, 압력수두에 따른 투수특성을 파악하였으며, Z형 강널말뚝 연결부분의 효과적인 지수방안을 강구하였다. Z형 강널말뚝의 장기적인 지수효과는 강널말뚝 연결부의 자연적인 막힘 현상에 의하여 얻을 수 있으며 단기적인 지수효과는 지수재 도포에 의하여 효과적으로 얻을 수 있다. 본 실험결과로 인하여 Z형 강널말뚝이 오염지역의 차폐에 효과적으로 적용될 수 있는 것으로 나타났다.

• 한국지반공학회논문집
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• 제21권1호
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• pp.43-50
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• 2005

고압분사주입공법은 지반개량, 차수벽, 흙막이벽, 기초 보강말뚝 등에 사용되고 있다. 고압분사주입공법은 사질토지반에 대해서는 지수목적으로, 연약한 점성토 지반에서는 지반강화를 위하여 사용되고 있다. 그러나 현재 국내에 적용되고 있는 경우의 대부분은 지반조건에 따른 강도증가 효과를 경험적으로 파악하여 설계에 적용하고 있는 실정이고 이에 대한 많은 연구가 진행되고 있다. 본 연구에서는 고압분사주입공법의 지반교란에의 효율성을 증대시킬 목적으로 공동현상(cavitation) 이론을 응용하고자 하였다. 그리고 이를 정량적으로 분석하기 위하여 공동현상(cavitation)을 적용한 경우와 적용하지 않은 경우에 대해 지반조건, 주입압력 및 주입시간 등을 변화시켜가며 점성토 및 사질토 모형지반에 대하여 그라우팅을 실시하였다. 시험결과 공동현상(cavitation)을 적용한 경우 점성토 및 사질토 지반 모두 좋은 결과를 보여, 실제 공법에 적용가능성이 높은 것으로 나타났다.

• 한국수소및신에너지학회논문집
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• 제28권1호
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• pp.40-46
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• 2017

We reviewed the electrical properties of SOFC anode manufactured using spherical Ni and nano YSZ powder. When core-shell is fabricated by using submicron Ni as core and nano-sized YSZ as shell for SOFC anode, the electrical conductivity of the $0.2{\mu}m$ Ni-YSZ core-shell was 3 times higher than that of $1.0{\mu}m$ NiO or $1.0{\mu}m$ Ni-YSZ. Hydrogen selectivity was similar at $800^{\circ}C$, but hydrogen selectivity and methane conversion rate under $750^{\circ}C$ was 10~25% higher, Power density was more than 2 times, ASR was about 1/3, when exposed to $H_2$ atmosphere at $750^{\circ}C$ for a long time, Ni particles did not have any growth or cut off conduction path.

• Neonatal Medicine
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• 제25권3호
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• pp.102-108
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• 2018

Purpose: Congenital diaphragmatic hernia (CDH) is rare but potentially fatal. The overall outcome is highly variable. This study aimed to identify a simple and dynamic parameter that helps predict the mortality of CDH patients in real time, without invasive tests. Methods: We conducted a retrospective chart review of 59 CDH cases. Maternal and fetal information included the gestational age at diagnosis, site of defect, presence of liver herniation, and lung-to-head ratio (LHR) at 20 to 29 weeks of gestational age. Information regarding postnatal treatment, including the number of days until surgery, the need for inhaled nitric oxide (iNO), the need for extracorporeal membrane oxygenation (ECMO), and survival, was collected. The highest respiratory severity score (RSS) within 24 hours after birth was also calculated. Results: Statistical analysis showed that a younger gestational age at the initial diagnosis (P<0.001), a lower LHR (P=0.001), and the presence of liver herniation (P=0.003) were prenatal risk factors for CDH mortality. The RSS and use of iNO and ECMO were significant factors affecting survival. In the multivariate analysis, the only remaining significant risk factor was the highest preoperative RSS within 24 hours after birth (P=0.002). The area under the receiver operating characteristic curve was 0.9375, with a sensitivity of 91.67% and specificity of 83.87% at the RSS cut-off value of 5.2. The positive and negative predictive values were 82.14% and 92.86%, respectively. Conclusion: Using the RSS as a prognostic predictor with simple calculations will help clinicians plan CDH management.

• 동의신경정신과학회지
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• 제9권2호
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• pp.45-51
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• 1998

Purpose : This study has an experiment on finding how Hyangbujapamultang advanced the learning and memory of rat to find the method to improve the failure of memory which is the symptom of dementia.Method : In the experiment, rats were divided the control group (14 rat) which medicate the excipient into the sample group (17 rat) which medicates Hyangbujapalmutang. And the learning ability test and the memorv test was practiced to using the task of radial arm maze.The learning ability test had the presupposition that, when a rat which frequents 8 tracks makes am error not exceeding one time for 3 days without a break, it passes the test.First experiment compared total days when the control group passed the test with total days when the sample group it.The memory test practiced after 24 hours when the learning ability test was over. When a rat frequents 4 tracks, the gates is cut off during 30 seconds. Here the number of error at the control group with that of the sample group.Result: In the learning ability test, the sample group needed 5.82${\pm}$0.37 days to pass the test and the control group needed 6.43${\pm}$0.67 days. In the memory test, the sample group errored 0.29${\pm}$0.37 times and the control group errored 1.86${\pm}$0.78 times.Conclusion : In the learning ability test, the sample group passed the test earlier than the control group, but any statistical correlationship couldn't be found in it. In the memory test, the sample group had the pregnant reduction of the number of error in comparison with the control group.

• Journal of Trauma and Injury
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• 제28권3호
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• pp.104-107
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• 2015

Purpose: Nitric oxide (NO) is a vasodilator and inhaled NO (iNO) is used in acute respiratory distress syndrome (ARDS) to improve alveolocapillary gas exchange. The mechanism to improve oxygenation is likely to redistribute blood flow from unventilated areas to ventilated areas. Though improvement of oxygenation, iNO therapy has not been shown to improve mortality and considered as only rescue therapy in severe hypoxemia. We conducted the study to investigate an efficacy of iNO in trauma patients with severe hypoxemia. Methods: We reviewed the trauma patients who underwent iNO therapy retrospectively from 2010 to 2014. Degree of hypoxemia was represented as $PaO_2/FiO_2$ ratio (PFR) and the severity of patient was represented with sequential organ failure assessment (SOFA) score. Patients were divided into the survivor group and non-survivor group according to the 28-day mortality. Results: A total of 20 patients were enrolled. The mortality of 28-day was 40%. There were no significant differences between survivor and non-survivor group in age, sex, severity of injury, PFR and SOFA score. There was significant difference in initiation time of iNO after injury (p=0.047). Maximum combinations of sensitivity and specificity for timing of iNO therapy were observed using cut-off of 3-day after injury with a sensitivity of 88% and specificity of 75%. Conclusion: Though iNO therapy does not influence the mortality, iNO therapy may decrease the mortality caused by respiratory failure in the early phase of trauma.

• Journal of Microbiology
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• 제44권1호
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• pp.106-112
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• 2006

In this study, the genetic diversities of multi-resistant Salmonella typhimurium (ST) isolates were analyzed via the application of both pulsed field gel electrophoresis (PFGE) and Polymerase chain reaction (PCR) analysis methods, using 6 kinds of primers (REP, ERIC, SERE, BOX, P-1254 and OPB-17). And their discriminative abilities (DA) were also compared in order to determine the most effective and reliable analysis method. 118 S. typhimurium isolates, cultured from diverse animals and human patients in Korea beginning in 1993, were analyzed and subjected to a comparison of Simpson's index of diversity (SID), using both PFGE and PCR methods. PFGE by XbaI enzyme digestion allowed for discrimination into 9 pulsotypes, with high SID values (0.991) on the genomic DNA level. This shows that PFGE is a very discriminative genotypic tool, and also that multiple clones of S. typhimurium isolates had existed in domestic animals and humans in Korea since 1993. However, we could ultimately not to trace the definitive sources or animal reservoirs of specific S. typhimurium isolates examined in this study. Depending on the SID values, the combined method (7 kinds of method) was found to be the most discriminative method, followed by (in order) SERE-PCR, REP-PCR, ERIC-PCR, PFGE & OPB-17 (RAPD), P-1254 (RAPD), and BOX-PCR at the $80\%$ clone cut-off value. This finding suggests that the REP-PCR method (which utilizes 4 primer types) may be an alternative tool to PFGE for the genotyping of S. typhimurium isolates, with comparable cost, time, and labor requirement. The establishment of a highly reliable and discriminatory method for epidemiologic analysis is considered necessary in order for researchers to trace the sources of specific pathogens and, consequently, to control and prevent the spread of epidemic S. typhimurium isolates to humans.