• Convergence Security Journal
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• v.12 no.1
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• pp.35-42
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• 2012

Increase of data traffic and the advent of new real-time services require to change from the traditional TDM-based (Time Division Multiplexing) networks to the optical networks that soft and dynamic configuration. Voice and lease line services are main service area of the traditional TDM-based networks. This optical network became main infrastructure that offer many channel that can convey data, video, and voice. To provide high resilience against failures, Packet-optical networks must have an ability to maintain an acceptable level of service during network failures. Fast and resource optimized lightpath restoration strategies are urgent requirements for the near future Packet-optical networks with a Generalized Multi-Protocol Label Switching(GMPLS) control plane. The goal of this paper is to provide packet-optical network with a hierarchical multi-layer recovery in order to fast and coordinated restoration in packet-optical network/GMPLS, focusing on new implementation information. The proposed schemes do not need an extension of optical network signaling (routing) protocols for support.

• Industrial Engineering and Management Systems
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• v.8 no.3
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• pp.181-193
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• 2009

This paper presents a framework for controlling mobile multiple robots connected by communication networks. This framework provides novel methods to control coordinated systems using mobile agents. The combination of the mobile agent and mobile multiple robots opens a new horizon of efficient use of mobile robot resources. Instead of physical movement of multiple robots, mobile software agents can migrate from one robot to another so that they can minimize energy consumption in aggregation. The imaginary application is making "carts," such as found in large airports, intelligent. Travelers pick up carts at designated points but leave them arbitrary places. It is a considerable task to re-collect them. It is, therefore, desirable that intelligent carts (intelligent robots) draw themselves together automatically. Simple implementation may be making each cart has a designated assembly point, and when they are free, automatically return to those points. It is easy to implement, but some carts have to travel very long way back to their own assembly point, even though it is located close to some other assembly points. It consumes too much unnecessary energy so that the carts have to have expensive batteries. In order to ameliorate the situation, we employ mobile software agents to locate robots scattered in a field, e.g. an airport, and make them autonomously determine their moving behaviors by using a clustering algorithm based on the Ant Colony Optimization (ACO). ACO is the swarm intelligence-based methods, and a multi-agent system that exploit artificial stigmergy for the solution of combinatorial optimization problems. Preliminary experiments have provided a favorable result. In this paper, we focus on the implementation of the controlling mechanism of the multi-robots using the mobile agents.

• The Korean Journal of Physiology and Pharmacology
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• v.6 no.3
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• pp.131-138
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• 2002

Thanks to recent progress in availability of molecular and functional techniques it became possible to search for the basic molecular and cellular processes that mediate and control $HCO_3{^-}$ and fluid secretion by the pancreatic duct. The coordinated action of various transporters on the luminal and basolateral membranes of polarized epithelial cells mediates the transepithelial $HCO_3{^-}$ transport, which involves $HCO_3{^-}$ absorption in the resting state and $HCO_3{^-}$ secretion in the stimulated state. The overall process of HCO3 secretion can be divided into two steps. First, $HCO_3{^-}$ in the blood enters the ductal epithelial cells across the basolateral membrane either by simple diffusion in the forms of $CO_2$ and $H_2O$ or by the action of an $Na^+-coupled$ transporter, a $Na^+-HCO_3$ cotranporter (NBC) identified as pNBC1. Subsequently, the cells secrete $HCO_3{^-}$ to the luminal space using at least two $HCO_3{^-}$ exit mechanisms at the luminal membrane. One of the critical transporters needed for all forms of $HCO_3{^-}$ secretion across the luminal membrane is the cystic fibrosis transmembrane conductance regulator (CFTR). In the resting state the pancreatic duct, and probably other $HCO_3{^-}$ secretory epithelia, absorb $HCO_3{^-}.$ Interestingly, CFTR also control this mechanism. In this review, we discuss recent progress in understanding epithelial $HCO_3{^-}$ transport, in particular the nature of the luminal transporters and their regulation by CFTR.

• Journal of the Korean Institute of Telematics and Electronics S
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• v.35S no.6
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• pp.36-45
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• 1998

This paper discusses multiple access control aspects for a wireless extension of high-speed asynchronous transfer mode(ATM) networks. One challenging requirement is that mobile systems convey of diverse types of information including voice, computer data, facsimile, and video data that have different quality of service constraints. Basically, a centralized control scheme for a coordinated multiple access is required in order to efficiently accommodate multimedia traffic on wireless links. The proposed scheme dynamically scheduling the mobile terminal, which has data to transfer according to the service, types at base station. In this scheme, the scheduling algorithm is performed on the basis of traffic descriptors and QoS parameters, which required in the connection set up phase. As a consequence, the transmission scheduling is very flexible and can account for the different traffic rate and delay constraints that emerge from voice and data integration. The simulation result shows that the proposed scheme has better performance over other scheduling algorithms.

• Molecules and Cells
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• v.38 no.10
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• pp.895-903
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• 2015

Non-coding microRNAs (miRNAs) regulate the translation of target messenger RNAs (mRNAs) involved in the growth and development of a variety of cells, including primordial germ cells (PGCs) which play an essential role in germ cell development. However, the target mRNAs and the regulatory networks influenced by miRNAs in PGCs remain unclear. Here, we demonstrate a novel miRNAs control PGC development through targeting mRNAs involved in various cellular pathways. We reveal the PGC-enriched expression patterns of nine miRNAs, including miR-10b, -18a, -93, -106b, -126-3p, -127, -181a, -181b, and -301, using miRNA expression analysis along with mRNA microarray analysis in PGCs, embryonic gonads, and postnatal testes. These miRNAs are highly expressed in PGCs, as demonstrated by Northern blotting, miRNA in situ hybridization assay, and miRNA qPCR analysis. This integrative study utilizing mRNA microarray analysis and miRNA target prediction demonstrates the regulatory networks through which these miRNAs regulate their potential target genes during PGC development. The elucidated networks of miRNAs disclose a coordinated molecular mechanism by which these miRNAs regulate distinct cellular pathways in PGCs that determine germ cell development.

• Journal of Veterinary Science
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• v.22 no.4
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• pp.48.1-48.15
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• 2021

Background: Porcine epidemic diarrhea virus (PEDV) is a swine enteropathogenic coronavirus that has devastated the swine industry in South Korea over the last 30 years. The lack of an effective method to control the endemics has led to a surge in PEDV recurrences in affected farms throughout the country. Objectives: In the first step toward establishing systematic monitoring of and active control measures over the swine populations, we constructed an assessment model that evaluates the status of (1) biosecurity, (2) herd immunity, and (3) virus circulation in each of the PEDV-infected farms. Methods: A total of 13 farrow-to-finish pig farms with a history of acute PEDV infection on Jeju Island were chosen for this study. The potential risk of the recurrence in these farms was estimated through on-site data collection and laboratory examination. Results: Overall, the data indicated that a considerable number of the PEDV-infected farms had lax biosecurity, achieved incomplete protective immunity in the sows despite multi-dose vaccination, and served as incubators of the circulating virus; thus, they face an increased risk of recurrent outbreaks. Intriguingly, our results suggest that after an outbreak, a farm requires proactive tasks, including reinforcing biosecurity, conducting serological and virus monitoring to check the sows' immunity and to identify the animals exposed to PEDV, and improving the vaccination scheme and disinfection practices if needed. Conclusions: The present study highlights the significance of coordinated PEDV management in infected farms to reduce the risk of recurrence and further contribute towards the national eradication of PEDV.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.8 no.3
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• pp.52-63
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• 2009

Recently in Korea, in the case of metropolis, the urban signalized intersections are controlled by traffic information center or ITS center. Cheon-an City also established traffic information center through the 1st.-$\sim$3rd. ITS public construction and has managed this center that includes bus information service, traffic information collection and providing service, parking information service, and traffic responsive control system. In the Cheon-an metropolitan traffic signal operation, traffic signal controllers were grouped by the each main traffic flow axes and performed with coordinated signal timing for the signalized arterials, and also cycle and split changed by realtime traffic demands. Cheon-an urban traffic responsive control system was evaluated by intersection delay and speed, then it was verified that the delay decreased and vehicle speed improved. However, the rural signal control system to connect adjacency town was evaluated to have lower status than urban area due to the unimproved TOD (Time of day) plan. Therefore actuated signal control was examined for substitutive control system in isolated signal intersection. The aim of this article is to compare actuated signal control with TOD mode in the rural intersection of Cheon-an and to fine superiority of these two control mode, with evaluation of vehicle delay by using HCM(2000) method and by micro-simulation CORSlM. The result of field test show that actuated signal control gave better performance in delay comparison than the existing TOD signal control. And simulation outcome verified that non-optimized TOD has higher delay than optimized TOD mode, non-optimal actuated mode, and optimal actuated signal control mode. Particularly, these three modes delays had not different values according to the paired sample t-test. This is because small traffic demands were loaded in each links. This suggested actuated signal control is expected to be more effective than TOD mode in some rural isolated intersections which frequently need to survey for traffic volume.

• Asian-Australasian Journal of Animal Sciences
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• v.13 no.6
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• pp.845-855
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• 2000

As high as 50% of pregnancies are known to fail and the majority of such losses occur during the peri-implantation period. For the establishment of pregnancy in mammalian species, therefore, implantation of the conceptus to the maternal endometrium must be completed successfully. Physiological events associated with implantation differ among mammals. In ruminant ungulates, an elongation of the trophohlast in early conceptus development is required before the attachment of the conceptus to the uterine endometrium. Moreover, implantation sites are restricted to each uterine caruncula where tissue remodeling, feto-maternal cell fusion and placentation take place in a coordinated manner. These unique events occur under strict conditions and are regulated by numerous factors from the uterine endometrium and trophoblast in a spatial manner. Interferon-tau (IFN-${\tau}$), a conceptus-derived anti-Iuteolytic factor, which rescues corpus luteum from its regression in ruminants, is particularly apt to play an important role as a local regulator in coordination with other factors, such as TGF-${\beta}$, Cox-2 and MMPs at the attachment and placentation sites.

• Korean Journal of Construction Engineering and Management
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• v.5 no.1 s.17
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• pp.124-132
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• 2004

A human resource management of the general contractors is to mostly deal with daily input by each subcontractor in construction fields. However, this way has some limitations; the identification of proper human-input and productivity, preventive activities or efforts for minimizing schedule delay. The reason why these limitations are that few systematic efforts through a coordinated field administration with the construction schedule planning and human resources. Therefore, on the basis of the construction schedule planning, human resource management of subcontractors is necessary to make for an improvement in construction schedule control. Daily Scheduling Check System(DSCS), as the linked human resources on an existed CPM scheduling software, was developed and this paper then verified validity and effectiveness of using the DSCS for the framework of some actual apartment construction projects

• Wind and Structures
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• v.11 no.2
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• pp.75-96
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• 2008

A better understanding of tornado-induced wind loads is needed to improve the design of typical structures to resist these winds. An accurate understanding of the loads requires knowledge of near-ground tornado winds, but observations in this region are lacking. The first goal of this study was to verify how well a CFD model, when driven by far field radar observations and laboratory measurements, could capture the flow characteristics of both full scale and laboratory-simulated tornadoes. A second goal was to use the model to examine the sensitivity of the simulations to various parameters that might affect the laboratory simulator tornado. An understanding of near-ground winds in tornadoes will require coordinated efforts in both computational and physical simulation. The sensitivity of computational simulations of a tornado to geometric parameters and surface roughness within a domain based on the Iowa State University laboratory tornado simulator was investigated. In this study, CFD simulations of the flow field in a model domain that represents a laboratory tornado simulator were conducted using Doppler radar and laboratory velocity measurements as boundary conditions. The tornado was found to be sensitive to a variety of geometric parameters used in the numerical model. Increased surface roughness was found to reduce the tangential speed in the vortex near the ground and enlarge the core radius of the vortex. The core radius was a function of the swirl ratio while the peak tangential flow was a function of the magnitude of the total inflow velocity. The CFD simulations showed that it is possible to numerically simulate the surface winds of a tornado and control certain parameters of the laboratory simulator to influence the tornado characteristics of interest to engineers and match those of the field.