• Journal of International Society for Simulation Surgery
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• 제2권2호
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• pp.83-86
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• 2015

Recently, computer-assisted surgery is popular for performing well-planned operations. Computer-aided navigation system is helpful in maxillofacial surgery with real time instrument positioning and clear anatomic identification. Generally, segmental mandibulectomy and reconstruction flap surgery have done by extra-oral approach such as, submandibular approach. This case report describes performing intra-oral segmental mandibulectomy and reconstruction with monocortical deep circumflex iliac artery (DCIA) flap and CT guided implant surgery by using computer-aided surgical guide and navigation for managing ameloblastoma in a 31 years old female patient.

• 대한치과의사협회지
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• 제52권10호
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• pp.596-601
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• 2014

Computer-aided surgery is popular and useful in the field of oral and maxillofacial surgery, because of the possibility of simulation with a high accuracy. In all aspects of surgery, proper planning facilitates more predictable operative results, however before the use of virtual planning, much of this relied on 2-dimensional (2-D) imaging for treatment planning on a 3-dimensional (3-D) object and surgical trial and error. With real-time instrument positioning and clear anatomic identification, a computer-assisted navigation system (CANS) is exceptionally helpful in maxillofacial surgery. These techniques enable performing precise bony ablation and reconstruction, and also decrease surgical time and donor site defect.

• Asian Pacific Journal of Cancer Prevention
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• 제17권7호
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• pp.3651-3658
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• 2016

Computer-aided diagnosis of breast cancer is an important medical approach. In this research paper, we focus on combining two major methodologies, namely fuzzy base systems and the evolutionary genetic algorithms and on applying them to the Saudi Arabian breast cancer diagnosis database, to aid physicians in obtaining an early-computerized diagnosis and hence prevent the development of cancer through identification and removal or treatment of premalignant abnormalities; early detection can also improve survival and decrease mortality by detecting cancer at an early stage when treatment is more effective. Our hybrid algorithm, the genetic-fuzzy algorithm, has produced optimized systems that attain high classification performance, with simple and readily interpreted rules and with a good degree of confidence.

• Journal of Electrical Engineering and Technology
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• 제4권1호
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• pp.28-34
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• 2009

In a Gas Insulated Substation (GIS), Very Fast Transients (VFTs) are generated mainly due to switching operations. These transients may cause internal faults, i.e., layer-to-layer faults in a capacitively graded bushing as it is one of the most important terminal equipment for GIS. The healthiness of the bushing is generally verified by measuring its leakage current. However, the change in current magnitude/pattern is only marginal for different types of fault conditions. Leakage current monitoring (LCM) systems generate large amounts of data and computer aided interpretation of defects may be of great assistance when analyzing this data. In view of the above, ANN techniques have been used in this study for identification of these minor faults. A single layer perceptron network, a two layer feed-forward back propagation network and cascade correlation (CC) network models are used to identify interlayer faults in the bushing. The effectiveness of the CC network over perceptron and back propagation networks in identification of a fault has been analysed as part of the paper.

• The Plant Pathology Journal
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• 제33권6호
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• pp.529-542
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• 2017

Control of plant diseases is largely dependent on use of agrochemicals. However, there are widening gaps between our knowledge on plant diseases gained from genetic/mechanistic studies and rapid translation of the knowledge into target-oriented development of effective agrochemicals. Here we propose that the time is ripe for computer-aided drug discovery/design (CADD) in molecular plant pathology. CADD has played a pivotal role in development of medically important molecules over the last three decades. Now, explosive increase in information on genome sequences and three dimensional structures of biological molecules, in combination with advances in computational and informational technologies, opens up exciting possibilities for application of CADD in discovery and development of agrochemicals. In this review, we outline two categories of the drug discovery strategies: structure- and ligand-based CADD, and relevant computational approaches that are being employed in modern drug discovery. In order to help readers to dive into CADD, we explain concepts of homology modelling, molecular docking, virtual screening, and de novo ligand design in structure-based CADD, and pharmacophore modelling, ligand-based virtual screening, quantitative structure activity relationship modelling and de novo ligand design for ligand-based CADD. We also provide the important resources available to carry out CADD. Finally, we present a case study showing how CADD approach can be implemented in reality for identification of potent chemical compounds against the important plant pathogens, Pseudomonas syringae and Colletotrichum gloeosporioides.

• 대한한의진단학회지
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• 제14권1호
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• pp.70-78
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• 2010

Objectives : To qualify or enhance the diagnostic ability of students in Oriental Medicine, so called standardized patients are ideal modality, but because it's a man-based method, more convenient tools are required. Computer-based diagnostic ability test program gives effective way for the very purpose. So we made a pilot software evaluating Pattern Identification ability in Oriental Medicine. Methods and Materials : The pilot software was coded with Microsoft's EXCEL VBA. 87 names of Zheng (Symptom Pattern) and 674 names of symptom (including some signs) are adopted from the former standardization works conducted by Korean Institute of Oriental Medicine (KIOM) in 1996. Results : Compared with some manned modalities to test Pattern Identification ability, the test by this software shows superiority in convenience and objectivity. Conclusion : This software is world's first program to perform computer-based evaluation of Pattern Identification in Oriental Medicine, and it gives effective way to complement both written test and manned clinical performance test (CPX).

• 한국콘텐츠학회논문지
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• 제11권11호
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• pp.185-193
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• 2011

결핵은 환자를 미리 발견하여 치료함으로서, 질병의 전파를 차단하여 새로운 감염자가 발생을 최소화하고, 결핵을 조기에 예방 및 진단하는 것이 중요하다. 그러므로 현재 의학에서는 디지털 의료영상을 활용하여 질병진단의 보조 수단으로서 컴퓨터자동진단시스템이 응용되고 있다. 본 연구에서 주성분 분석(PCA)과 질감분석(Texture features)의 알고리즘을 이용하여 결핵의 질병을 자동으로 판별 및 인식하였으며, 그 기준에 따라 디지털 흉부 방사선영상에서 컴퓨터자동진단의 실용화를 위한 선행연구를 하였다. 실험결과는 주성분분석을 이용한 병변 인식률은 전문의의 질병에 대한 판독률보다 낮게 나타났지만, 질감분석의 인식률은 전문의 판독결과보다 높은 병변 인식률을 나타내었다. 그러므로 제안하는 알고리즘을 활용한 컴퓨터자동진단시스템은 임상의사에게 부가적인 보조 수단으로서 예비판독 단계의 정보를 제공하여 질병의 조기진단 및 예방이 가능할 것으로 사료된다.

• 시스템엔지니어링학술지
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• 제7권1호
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• pp.53-56
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• 2011

Configuration management plays a key role in systems engineering process for any project from earlier stage of development. It consists of five major activities, ie., configuration management planing, configuration identification, configuration control, configuration status accounting and configuration verification and audit, and is essential to control system design, development and operation throughout entire life cycle of the system development. And it is directly associated with other part of systems engineering management process, ie., technical data management which provides traceability of important decisions and changes during development. In this paper, we describe how to apply CASE(Computer-aided Systems Engineering) tool-Cradle for the configuration management to achieve effectiveness of Technical Management process.

• Journal of International Society for Simulation Surgery
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• 제3권2호
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• pp.74-76
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• 2016

Computer-aided navigation system is helpful in maxillofacial surgery with real time instrument positioning and clear anatomic identification. Generally, completely impacted tooth extraction surgery have e high risk by iatrogenic injury such as, adjacent tooth injury, normal anatomical structure injury. This case report describes performing extraction of impacted supernumerary teeth on anterior maxilla by using the navigation system in a 15 years old male patient.

• Journal of Computational Design and Engineering
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• 제3권4호
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• pp.370-384
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• 2016

Computer-aided materials design requires new modeling approaches to characterize and represent fine-grained geometric structures and material compositions at multiple scales. Recently, a dual-Rep approach was developed to model materials microstructures based on a new basis function, called surfacelet. As a combination of implicit surface and wavelets, surfacelets can efficiently identify and represent planar, cylindrical, and ellipsoidal geometries in material microstructures and describe the distribution of compositions and properties. In this paper, these primitive surfacelets are extended and composite surfacelets are proposed to model more complex geometries. Composite surfacelets are constructed by Boolean operations on the primitives. The surfacelet transform is applied to match geometric features in three-dimensional images. The composition of the material near the identified features can then be modeled. A cubic surfacelet and a v-joint surfacelet are developed to demonstrate the reverse engineering process of retrieving material compositions from material images.