• Biodesign
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• 제6권4호
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• pp.92-95
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• 2018

API5 is a unique oncogenic, non-BIR type IAP nuclear protein and is up-regulated in several cancers. It exerts several functions, such as apoptosis inhibition, cell cycle progression, cancer immune escape, and anticancer drug resistance. Although structural studies of API have revealed that API5 mediates protein-protein interactions, its detailed molecular functions remain unknown. Since FGF2 is one of API5's major interacting proteins, structural studies of the API5-FGF2 complex will provide insight into both proteins' molecular function. We overexpressed and purified API5 and FGF2 in Escherichia coli and crystallized the API-FGF2 complex using polyethylene glycol (PEG) 6000 as a precipitant. Diffraction data were collected to a $2.7{\AA}$ resolution using synchrotron X-rays. Preliminary diffraction analysis revealed that the API5-FGF2 complex crystal belongs to the space group $P2_12_12_1$ with the following unit cell parameters: a = 46.862, b = 76.523, $c=208.161{\AA}$. One asymmetric unit with 49.9% solvent contains one API5-FGF2 complex. Molecular replacement calculation, using API5 and FGF2 coordinates, provided a clear electron density map for an API5-FGF2 complex.

• 한국생물물리학회:학술대회논문집
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• 한국생물물리학회 2002년도 제9회 학술 발표회 프로그램과 논문초록
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• pp.16-17
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• 2002

The major histocompatibility complex (MHC) is an important susceptibility locus for many human autoimmune diseases. The structural and functional properties of HLA-DR molecules that are associated with susceptibility to several autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis, have been defined.(omitted)

• Korean Journal of Mathematics
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• 제26권4호
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• pp.809-822
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• 2018

In this paper, we introduce complex valued dislocated metric spaces. We prove Banach contraction principle, Kannan and Chatterjea type fixed point theorems in this new space. Moreover, we give some applications of the results to differential equations and iterated functions.

• 한국항해항만학회지
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• 제30권9호
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• pp.763-766
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• 2006

In this paper, the EM wave absorbers were designed and fabricated for X -band sensors using Carbon of dielectric material with CPE. The complex relative permittivity of samples is calculated by using measurement results of S-parameter. We simulated the double-layered type EM wave absorber with broad bandwidth using the measured complex relative permittivity by changing the thickness and layer, which was fabricated based on the simulated design The fabricated EM wave absorber consists of 1 mm first layer sheet facing metal with Carbon composition ratio 70 vol. % and 1.5 mm second layer sheet with Carbon composition ratio 60 vol. %. The measured results showed a good agreement to the simulated ones. It is found toot the optimized absorption ability of double-layered type EM wave absorber with thickness of 2.5 mm is higher than 10 dB from 7.8 GHz to 13.3 GHz.

• 대한기계학회논문집
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• 제16권7호
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• pp.1255-1265
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• 1992

본 연구에서는 단열 및 온도가 영으로 고정된 경계조건을 갖는 대칭 입술형과 대칭 익형 강체함유 물상의 접합경계면 균열에 대한 Hilbert 문제로부터 복소 포텐셜 함수와 커스프 균열선단 그리고 접합경계면 균열선단에서 TSIF를 구하고자 한다.

• 한국언어정보학회지:언어와정보
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• 제16권1호
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• pp.25-43
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• 2012

This study introduces set-denoting time expressions in Korean, which can be divided into simple and complex types. It was found that while the simple type expressions are easily represented within ISO-TimeML, a time-expression markup language, some complex type set-denoting expressions are not. Therefore, this study analyzes the reason for these difficulties in representing complex type expressions, as well as suggests the introduction of @measure and @interpretation attributes in the TIMEX3 tag. The @measure attribute represents the time interval, and the @interpretation attribute is used to distinguish distributive readings from cumulative readings. Additionally this paper suggests that a mapping between these and other attributes are required in TLINK.

• 한국실내디자인학회논문집
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• 제20권2호
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• pp.47-54
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• 2011

In Alvar Aalto's designs, important factors of complex building designs including Wolfsburg cultural center are that they insinuate how to develop each architectural type and how to combine them in a building. The humane and physical background studies, and wholistic and systematic approaches are adopted to fulfill research purposes. Comparison with other buildings are necessary to reveal true meaning of this building. The result of analysis show characteristics of Wolfsburg cultural center as follows; hybrid composition of mass and elevation, spatial effect using level difference and light, massing variation of roof, and creating space for various activities. Wolfsburg cultural center designed in late 1950s has greatly affected Aalto's later works through various architectural experiments because it is the first cultural complex project that combined various architectural types. Especially library in the cultural center has shown transitional characteristics to famous fan-type libraries of 1960s while maintained features about Viipuri library. Wolfsburg cultural center act as an another type which present new principles of clustering, massing and exterior design. Its true meaning lies in forming a humanizing place beyond spatial configuration.

• Journal of Acupuncture Research
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• 제33권3호
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• pp.181-187
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• 2016

Objectives : The purpose of this study is to report the clinical effects of 8 constitution acupuncture on a patient with complex regional pain syndrome (CRPS) type I. Methods : In this study, a patient with CRPS was treated by 8 constitution acupuncture therapy. He was diagnosed in the Cholecystonia of 8 constitution diagnosis. The progress of symptoms were evaluated by visual analog scale (VAS) and sleeping time. VAS and sleeping time were evaluated at 7:00 am daily. Results : VAS decreased from 10 to 4, while sleeping time increased from 30 minutes to 3 hours. Conclusion : The results suggest that 8 constitution acupuncture is effective for treating symptoms of CRPS type I.

• 한국산학기술학회논문지
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• 제14권11호
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• pp.5971-5978
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• 2013

본 연구는 저탄소 사회실현 및 녹색성장을 주도하기 위한 스마트 그린 복합단지의 조성을 위하여 복합단지의 개발유형을 검토하고 유형별로 토지이용의 모형을 설정함으로써 스마트 그린 복합단지의 미래적 개발방향을 제시하는데 목적을 두고 있다. 연구의 순서로는 이론고찰을 통해 스마트 그린 복합단지의 개념과 개발측면에 대해 검토하고 복합단지의 개발유형을 단지규모와 기능배분 등 두 가지로 구분하여 설정함으로써 토지이용모형의 준거를 마련한다. 이를 토대로 국내에서 수용 가능한 복합단지 유형을 단지규모에 따라 세 가지로 구분하며, 스마트 그린 복합단지의 개발유형별 토지이용 모형을 설정하기 위한 기준을 이론과 사례단지의 분석결과를 토대로 제시하고 유형별 토지 이용 모형을 구축함으로서 스마트 그린 복합단지의 미래 개발방향을 국내의 시사적 관점에서 제시하였다.

• 한국항해항만학회:학술대회논문집
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• 한국항해항만학회 2006년도 International Symposium on GPS/GNSS Vol.1
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• pp.297-300
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• 2006

In this paper, the EM wave absorbers were designed and fabricated for X-band sensors using Carbon of dielectric material with CPE. The complex relative permittivity of samples is calculated by the measured S-parameter data. We simulated the double-layered type EM wave absorber with broad bandwidth using the measured complex relative permittivity by changing the thickness and layer, which was fabricated based on the simulated design. The fabricated EM wave absorber consist of 1mm first layer sheet facing metal with Carbon composition ratio 70 vol% and 1.5 mm second layer sheet with Carbon composition ratio 60 vol%. The comparisons of simulated and measured results are good agreement. As a result, the optimized absorption ability of double-layered type EM wave absorber with thickness of 2.5 mm is higher than 10 dB from 7.8 GHz to 13.3 GHz.