• Title/Summary/Keyword: complex extract

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Effects of Ascaris suum Extract and Sulfamethoxazole on Allergic Airway Inflammation

  • Cho, Eun-Sang;Park, Bae-Keun;Son, Hwa-Young
    • Biomolecules & Therapeutics
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    • v.19 no.4
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    • pp.466-471
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    • 2011
  • Allergic asthma is complex inflammatory airway disorder caused by genetic and environmental factors. Sulfamethoxazole, a sulfonamide, is the cause of drug rash with eosinophilia and systemic symptoms syndrome. Parasites infection also related with eosinophilia and allergic diseases. In the present study, we investigated the modulating effects of parasitic derivative and sulfamethoxazole (SMX) on allergic airway inflammation in the ovalbumin (OVA)-induced murine asthma model. Histopathological changes, cytokine secretion, and total and allergen-specific IgE were investigated. BALB/c mice were treated with Ascaris suum extract or SMX for 4 weeks before sensitized and challenged to ovalbumin. Pre-treatment of Ascaris suum extract decreased allergic inflammation in lung tissue and IL-4, total IgE, and OVA-specific IgE levels in bronchoalveolar lavage fluid. However, pre-treatment of SMX did not show any effects on allergic airway inflammation. These results indicate that parasitic infection has protective effects on allergic asthma, but the sulfamamides may not relate with allergic asthma.

Effects of Angelica keiskei Koidzumi and Turmeric Extract Supplementation on Serum Lipid Parameters in Hypercholesterolemic Diet or P-407-Induced Hyperlipidemic Rats (명일엽과 울금 추출물의 투여가 고콜레스테롤식이와 P-407로 유도한 고지혈증쥐의 혈중 지질 함량에 미치는 영향)

  • Kim, Tae-Hyun;Son, Yeon-Kyung;Hwang, Keum-Hee;Kim, Mi-Hyun
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.37 no.6
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    • pp.708-713
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    • 2008
  • The effects of administration alone or mixed of Angelica keiskei and turmeric extract on blood lipids were evaluated in hypercholesterolemic diet or P-407-induced hyperlipidemic rats. In the study 1, female Sprague-Dawley rats weighing 160-180 g were divided into each groups and fed high cholesterol diets for 8 weeks. Experimental groups were administered with following diets: basal diet (Normal), high cholesterol diets (1% cholesterol). We did the oral administration for evaluation in experimental groups: C (vehicle), A (angelica extract), T (turmeric extract), AT (angelica extract, turmeric extract/ 1:1 complex). The concentrations of serum total cholesterol, and LDL-cholesterol were decreased by 6.8%, 9.8% in A group, by 22.1%, 28.8% in C group and by 28.2%, 35.6% in AT group, compared to the C group, respectively. HDL-cholesterol levels were not different among the experimental groups. In the study 2, we induced the hypertriglyceridemia in rats by intraperitoneal injection of P-407 (0.5 g/kg) once per three days. From the next day after P-407 injection beginning, we did the oral administration as the study 1. Angelica keiskei extract, turmeric extract and complex extract decreased serum triglyceride by 17.2%, 19.7% and 48.3%, respectively. These results suggested that Angelica keiskei and turmeric extract complex might have synergistic effect in lowering total cholesterol, LDL-cholesterol and triglyceride in hyperlipidemic rats.

Production of High Viscous Hyaluronic Acid Complex from Klebsiella sp. L-10 NTG 50 (Klebsiella sp. L-10의 NTG 50 변이주에 의한 고점성 히아루론산 복합체의 생산)

  • Lee, Hyaung-Sook;Choi, Young-Jun;Lee, Jong-soo
    • The Journal of Natural Sciences
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    • v.8 no.1
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    • pp.33-39
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    • 1995
  • Klebsiella sp. L-10 was treated with physical and chemical mutagens, and one of the NTG mutant which increased hyaluronic acid complex yield 2.5 folds was selected. The yield of hyaluronic acid complex from Klebsiella sp. L-10 NTG 50 mutant reached maximum level I the YPD medium containing 0.1% yeast extract, 3% Bacto-tryptone, 3% dextrose, each 30mM of $K_2HPO_4$ and $KH_2PO_4$ (pH 6.0-6.5) with shaking culture at $37^{\circ}C$ for 24 hrs, and 2900mg of hyaluronic acid complex per litre of culture was produced under the above condition.

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Effect of media compositions on carbohydrolase complex production in Lentinus edodes

  • Park, Jeom-Seok;Choe, Min-Gu;Ji, Yeong-Min;Choe, Jeong-U;Hong, Eok-Gi
    • 한국생물공학회:학술대회논문집
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    • 2003.04a
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    • pp.209-212
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    • 2003
  • This study was to investigate the effects of media components on carbohydrolase complex production in liquid culture of Lentinus edodes. Glucose and yeast extract, and $MgSO_4\;.\;7H_2O$ were selected as carbon, nitrogen, and mineral sources, respectively. The production level of ${\beta}-glucosidase$, one of carbohydrolase complex, was high. On the other hand, ${\beta}-glucuronidase$ and ${\beta}-galactosidase$ production levels were very low, which remain to be improved.

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New Approach to Investigate the Dynamic Relaxaton Process of Complex Peak in Mechanical and dielectric Characteristics of Anelastic Solids

  • Kim, Bong-Heup
    • Electrical & Electronic Materials
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    • v.11 no.10
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    • pp.1-5
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    • 1998
  • Complex dynamic relaxation processes of mechanical as well as dielectric character in polymeric anelastic solids are closely related through the movement of molecular chain segment in morphological structure, and the morphology can easily be modified by the treatments such as mechanical drawing or irradiation, those of which result, in turn, the complicated change on the appearance of the observed complex relaxation peak. In order to extract any meaningful understanding from the modified appearance of the peak, the relaxation peak must be resolved into the sum of the dynamic single relaxation peaks, each of which can be characterized respectively by three factors such as activation energy, magnitude of peak height and peak point temperature on the temperature dependent characteristics.

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Strong Uncorrelated Transform Applied to Spatially Distant Channel EEG Data

  • Kim, Youngjoo;Park, Cheolsoo
    • IEIE Transactions on Smart Processing and Computing
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    • v.4 no.2
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    • pp.97-102
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    • 2015
  • In this paper, an extension of the standard common spatial pattern (CSP) algorithm using the strong uncorrelated transform (SUT) is used in order to extract the features for an accurate classification of the left- and right-hand motor imagery tasks. The algorithm is designed to analyze the complex data, which can preserve the additional information of the relationship between the two electroencephalogram (EEG) data from distant channels. This is based on the fact that distant regions of the brain are spatially distributed spatially and related, as in a network. The real-world left- and right-hand motor imagery EEG data was acquired through the Physionet database and the support vector machine (SVM) was used as a classifier to test the proposed method. The results showed that extracting the features of the pair-wise channel data using the strong uncorrelated transform complex common spatial pattern (SUTCCSP) provides a higher classification rate compared to the standard CSP algorithm.

3D BUILDING RECONSTRUCTION FROM AIRBORNE LASER SCANNING DATA

  • Lee, Jeong-Ho;Han, Soo-Hee;Yu, Ki-Yun;Kim, Yong-Il
    • Proceedings of the KSRS Conference
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    • 2007.10a
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    • pp.587-590
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    • 2007
  • The demand for more accurate and realistic 3D urban models has been increasing more and more. Many studies have been conducted to extract 3D features from remote sensing data such as satellite images, aerial photos, and airborne laser scanning data. In this paper a technique is presented to extract and reconstruct 3D buildings in urban areas using airborne laser scanning data. Firstly all points in a building were divided into some groups by height difference. From segmented laser scanning data of irregularly distributed points we generalized and regularized building boundaries which better approximate the real boundaries. Then the roof points which are subject to the same groups were classified using pre-defined models by least squares fitting. Finally all parameters of the roof surfaces were determined and 3D building models were constructed. Some buildings with complex shapes were selected to test our presented algorithms. The results showed that proposed approach has good potential for reconstructing complex buildings in detail using only airborne laser scanning data.

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Fermentative Production of Succinic Acid from Glucose and Corn Steep Liquor by Anaerobiospirillum succiniciproducens

  • Lee, Pyung-Cheon;Lee, Woo-Gi;Lee, Sang-Yup;Chang, Ho-Nam;Chang, Yong-Keun
    • Biotechnology and Bioprocess Engineering:BBE
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    • v.5 no.5
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    • pp.379-381
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    • 2000
  • Anaerobiospirillum succiniciproducens requires expensive complex nitrogen sources such as yeast extract and polypeptone for its growth and succinic acid production. It was found that A. succiniciproducens was able to grow in a minimal medium containing glucose when supplemented with corn steep liquor (CSL) as the sole complex nitrogen source. The concentration of CSL had a significant effect on the glucose consumption by A. succiniciproducent. When 10-15 g/L of CSL was supplemented, cells were grown to an OD(sub)600 of 3.5 and produced 17.8 g/L succinic acid with 20 g/L glucose. These results are similar to those obtained by supplementing yeast extract and polypeptone, thereby suggesting that succinic acid can be produced more economically using glucose and CSL.

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