• 한국수소및신에너지학회논문집
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• 제30권2호
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• pp.188-192
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• 2019

Comparative studies between single- and two-stage expansion process using LNG cold heat have been performed for a closed Rankine power generation cycle. PRO/II with PROVISION release 10.0 from Schneider Electric Company was used, and the Peng-Robinson equation of state model with Twu's alpha function was selected for the modeling and optimization of the power generation cycle using LNG cold heat. In two-stage power generation cycle, 6.7% more power was obtained compared to that of single-stage power generation cycle through the optimization works.

• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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• pp.65.2-65.2
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• 2003

88 selective COX-2 inhibitors belonging to three chemical classes (triaryl rings, diaryl cycloalkanopyrazoles, and diphenyl hydrazides) were studied using comparative molecular field analysis (CoMFA) and comparative molecular similarity indices analysis (CoMSIA). Partial least squares analysis produced statistically significant models with q values of 0.84 and 0.79 for CoMFA and CoMSIA, respectively. The key spatial properties were detected by careful analysis of the isocontour maps. The binding energies calculated from flexible docking correlated with inhibitory activities by the least-squares fit method. (omitted)

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제17권11호
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• pp.2903-2923
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• 2023

Knowledge recommendation is a type of recommendation system that recommends knowledge content to users in order to satisfy their needs. Although using graph neural networks to extract data features is an effective method for solving the recommendation problem, there is information loss when modeling real-world problems because an edge in a graph structure can only be associated with two nodes. Because one super-edge in the hypergraph structure can be connected with several nodes and the effectiveness of knowledge graph for knowledge expression, a dual-channel hypergraph convolutional neural network model (DCHC) based on hypergraph structure and knowledge graph is proposed. The model divides user data and knowledge data into user subhypergraph and knowledge subhypergraph, respectively, and extracts user data features by dual-channel hypergraph convolution and knowledge data features by combining with knowledge graph technology, and finally generates recommendation results based on the obtained user embedding and knowledge embedding. The performance of DCHC model is higher than the comparative model under AUC and F1 evaluation indicators, comparative experiments with the baseline also demonstrate the validity of DCHC model.

• 한국산학기술학회논문지
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• 제13권11호
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• pp.5350-5355
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• 2012

사람의 티로시나제는 사람의 피부색을 결정하는 멜라닌 생합성의 첫 번째 반응을 촉매하며, 이 단계는 반응 속도를 결정하는 가장 중요한 단계이다. 따라서, 많은 화장품 회사들은 hTyr의 저해제를 찾고자 하였으나 사람 티로시나제의 3차원구조의 부재로 구조기반의 가상탐색은 불가능하다. 따라서 본 연구에서는 구조기반의 저해제 탐색을 위하여 기존에 그 구조가 알려진 Bacillus megaterium의 티로시나제의 3차 구조를 이용하여 인간 티로시나제의 3차원 구조를 상동모델링법으로 예측하였다. 3차원 구조 분석 결과 인간 티로시나제의 활성부위에 위치한 여섯 개의 히스티딘 잔기가 2개의 구리원자와 결합할 수 있으며, 이 활성부위는 단백질의 안쪽에 위치함을 알 수 있었다. 기질 또는 저해제가 결합할 수 있는 결합부위는 단백질의 표면에서 안쪽 깊은 곳의 활성부위와 연결되어 있으며 입구 쪽은 넓고 납작했으며 활성부위로 갈수록 좁아지는 깔대기와 같은 모양의 구조를 하고 있었다. 자체 제작 소프트웨어를 활용하여 solvent accessible surface를 만들고 여기에 가장 최적의 위치 및 형태를 갖는 모델을 티로신과 저해제로 가장 잘 알려진 코직산의 결합모델을 제안하였다. 이 결과 티로신과 코직산의 페놀그룹의 히드록시 기능단의 산소가 정확히 구리와 배위결합하는 것을 알 수 있었다. 결론적으로 본 연구 결과는 새로운 미백제를 설계하고 스크리닝하는데 유용한 정보를 제공할 수 있을 것으로 사료된다.

• 한국화재소방학회:학술대회논문집
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• 한국화재소방학회 2008년도 추계학술논문발표회 논문집
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• pp.86-92
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• 2008

On this study, modeling works using Cone tools simulation method were made for the prediction of real fire test results such as small to large scale fire tests including ISO 5660-1, EN 13823 and ISO 13784-1. For those simulation prediction, three real fire tests were performed in advance. In addition, Real data from ISO 5660-1 test were applied to this simulation modeling. Finally, the comparative analysis between Real fire tests and Simulation results were made out. Also, the Classifying evaluation by EURO Class using EN 13501-1 were taken off.

• 대한음성학회:학술대회논문집
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• 대한음성학회 2002년도 11월 학술대회지
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• pp.197-200
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• 2002

In this paper, we propose a phoneme duration modeling in a speech recognition system based on disicion tree state tying. We assume that phone duration has a Gamma distribution. In a training mode, we model mean and variance of each state duration in context-independent phone model based on decision tree state tying. In a recognition mode, we get mean and variance of each context-dependent phone duration form state duration information obtaind during training mode. We make a comparative study of the proposed meth with conventinal methods. Our method results in good performance compared with conventional methods.

• 한국자동차공학회논문집
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• 제11권5호
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• pp.156-162
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• 2003

The shock absorber is a part having a direct influence on the ride comfort, stability and dynamic load prediction of a vehicle. Thus, a rationally modeled shock absorber should be required in the dynamic analysis of vehicles. This thesis presents a modified model, based on Worden's hyperbolic tangent function, in order to fit experimental data on the velocity-damping force of a shock absorber. The hyperbolic tangent function correctly indicates the characteristics of a shock absorber, and has the advantage of containing physical causality. To evaluate the method, comparative evaluations of the linear model, the 5th polynomial model and Worden's model were carried out. The function presented in this paper is not only simple but also makes it possible to estimate the function coefficients easily and visually. In addition, it has the advantage of containing physical causality. Lastly, it effectively models the damping force of a shock absorber.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2001년도 춘계학술대회 논문집
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• pp.971-974
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• 2001

In this study, the static and dynamic characteristics of endmilling process was modelled and the analytic realization of chatter mechanism was discussed. In this regard, We have discussed on the comparative assessment of recursive time series modeling algorithms that can represent the machining process and detect the abnormal machining behaviors in precision endmilling operation. In this study, simulation and experimental work were performed to show the malfunctional behaviors. For this purpose, new recursive(RLSM) were adopted for the on-line system identification and monitoring of a machining process, we can apply these new algorithms in real process for detection of abnormal chatter. Also, the stability lobe of chatter was analysed by varying parameter of cutting dynamices in regenerative chatter mechanics.

• 한국소성가공학회:학술대회논문집
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• 한국소성가공학회 2006년도 춘계학술대회 논문집
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• pp.288-291
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• 2006

Piercing or blanking process is widely used to manufacture most of lead frame parts, but it is difficult to analyze the real process by the actual shape through progressive dies. In this paper several stages in progressive punching are modeled by 2D and 3D configurations using $DEFORM^{TM}$ 2D/ 3D code. During the progressive stage some state variables and deformed configurations are analyzed in each model. There are three stages in the process, the deformations at each stage are cumulative. The advantages and disadvantages of these two type modeling are discussed and analyzed. The experiments are performed as a working material copper alloy through manufactured die. Computed results in load by two types are compared to experiments.

• 한국공작기계학회논문집
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• 제10권4호
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• pp.76-83
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• 2001

In this study, the static and dynamic characteristics of turning process was modelled and the analytic realization of regen-erative chatter mechanism was discussed. In this regard, we have discussed on the comparative assessment of recursive times series modeling algorithms that can represent the machining process and detect the abnormal machining behaviors in precision turning operation. In this study, simulation and experimental work were performed to show the malfunction behaviors. For this purpose, new Recursive Extended Instrument Variable Method(REIVM) was adopted for the on-line system identification and monitoring of a machining process. Also, we can apply REIVE algorithms in real process for the detection of chatter frequency and dynamic property and analyze the stability lobe of the system by changing a parameter of cutting dynamics in regenerative chatter mechanics, if it is stable or unstable, Also, The stability lobe of chatter was analysed.