• 한국식품영양과학회지
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• 제38권2호
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• pp.136-141
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• 2009

스피루리나를 세포벽 가수분해효소와 단백질 가수분해효소로 처리하여 조제한 스피루리나 가수분해물(enzymatic hydrolysate of spirulina, EHS)의 생리활성을 조사하였다. 효소처리 가수분해물의 유산균 증식효과, 항산화능, 암세포 증식저해 활성, 항혈전 활성을 분석한 결과 EHS는 유산균 증식활성과 항산화능에 큰 영향을 미치지 않았으며, 자궁경부암세포(HeLa)에 대해 1.42 mg/L의 농도에서 15% 미만의 증식저해효과를 나타내었다. 반면 항혈전 활성을 공통 경로(common pathway), 내인성 경로(intrinsic pathway), 외인성 경로(extrinsic pathway)로 구분하여 측정한 결과, 공통경로, 내인성 경로와 유사한 항혈전 활성이 있음을 확인하였다. 공통 경로를 thrombin time assay로 측정한 결과 EHS의 농도가 100 mg/L일 때 155.6초를 나타내었다. 내인성 경로는 activated partial thromboplastin time assay로 측정하였고, EHS의 농도가 1000 mg/L일 때 95.8초를 나타내었다. 외인성 경로를 prothrombin time assay로 측정한 결과 EHS의 농도가 1000 mg/L일 때 10.6초를 나타내었다. 결과적으로 스피루리나 효소가수분해물(EHS)이 항혈전경로 중 공통경로와 내인성 경로에 활성이 있음을 알 수 있었으며, 이를 토대로 신규의 항혈전 기능성 원료로 개발될 수 있을 것으로기대된다.

• 대한건축학회논문집:계획계
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• 제35권4호
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• pp.45-52
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• 2019

The most ordinary form of residential type in Korea is a plate-type apartment, and the common space in these apartment is attracting as an important factor for enhancing social exchanges among neighbors and forming community consciousness. In addition, it provides a sense of psychological security by enabling natural exchanges and communication in contemporary society. It is desirable to plan the flow of space in such a way that private, semi-private, semi-public, and public spaces are linked. Semi-private and semi-public spaces can be defined as common spaces. Semi-private spaces are strongly recognized in the order of unit household entrance, main entrance, elevator, corridor, staircase, playground, bench, trail, walkway and parking lot, exercise space, main/back gate, the ability to gratify is increased sense of belonging, ownership consciousness formation, defensive function. Semi-public space is strongly recognized in the order of playground, bench, exercise space, trail, main entrance, walkway and parking lot, unit household entrance, main/back gate, corridor, staircase, elevator, the ability to gratify is increase of social contact, Secondary activity space function. In addition, the function to gratify in the common space differs according to gender and age group among resident characteristics, and differs according to corridor type, parking lot type and main entrance type. Therefore, differentiated planning of common space is needed in consideration of these differences in the design of common space in future.

• 한국작물학회지
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• 제50권5호
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• pp.336-339
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• 2005

Common thistle contains water-soluble substances that are antioxidative to foods. Antioxidant activities measured by DPPH method for the ground samples were the greatest in leaves, although was less than that of commonly used antioxidants, BHT and ascorbic acid. Methanol extracts and fractions from Xanthium occidentale plants dose-dependently increased DPPH free radical scavenging activity, in vitro test. The extracts from leaves showed the strongest antioxidant activity. DPPH scavenging activity of the individual fraction was in order of n-butanol>water>ethyl acetate>n-hexane fraction. By means of HPLC analysis, leaf samples of Xanthium occidentale had the highest amount of phenolic compounds, related with antioxidant activity, and followed by stems and roots. Total content of these antioxidant phenolic com­pounds for leaves extracts were detected in water fraction (36.7 mg 100 $g^{-1}$) as the greatest amount, especially chlorogenic acid (39.4 mg 100 $g^{-1}$) was the greatest component. These results suggest that Xanthium occidentale plants had potent antioxidant activity, and their activities were differently exhibited depending on plant part and fraction.

• 한국재난관리표준학회지
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• 제1권4호
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• pp.41-49
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• 2008

최근 국내 교량이 장대화 됨에 따라 많은 교량관리시스템(BMS)이 자체적으로 개발되어 운용 중에 있다. 그러나 각 시스템 개발자별로 구축한 상이한 데이터체계는 국가차원의 통합 체계를 구축하는데 큰 문제점으로 지적되고 있다. 본 연구는 교량 유지관리 시스템 개발 시 참조할 만한 공통의 자료모델을 개발하는데 그 목적이 있다. 이를 위해 법령에 따라 수행되는 교량 유지관리 업무와 기존에 개발된 시스템을 분석하였다. 분석된 내용을 바탕으로 교량 유지관리 활동을 4가지의 기본 업무형태로 구분하였으며, 구분된 기본 업무형태에 따라 필요한 공통의 자료모델을 도출하였다.

• 한국자원식물학회지
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• 제24권5호
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• pp.622-627
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• 2011

본 연구는 시판되고 있는 10종의 녹비작물로부터 추출한 추출물을 이용하여 감자 더뎅이병균(Streptomyces scabiei)에 대한 항균활성을 검정함으로서 감자 더뎅이병 경감을 위한 녹비작물 선발의 기초자료로 활용하고자 하였다. 10종의 녹비작물에 대하여 hexane, ether, ethylacetate, methanol 및 water로 순차적으로 용매분획을 하였다. 그 결과 DPPH free radical 소거능은 ether, methanol 및 water 추출물에서 소거능이 높게 나타났다. 감자 더뎅이병균(Streptomyces scabiei)에 대한 항균활성은 methanol, ethylacetate, ether 및 water 용매를 이용한 모든 녹비작물 추출물의 0.25 mg/mL 농도에서부터 높은 항균활성을 나타내었다. 특히, methanol 용매를 이용한 하우스솔고 추출물은 감자 더뎅이병균에 대하여 다른 녹비작물 보다 더 높은 항균력을 나타내었다. 이상의 결과들로부터 하우스솔고의 이용은 감자 더뎅이병 경감을 위한 최적의 녹비작물로 생각되었다.

• 대한임상검사과학회지
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• 제38권1호
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• pp.65-71
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• 2006

We examined the relationship between the basic characteristics and types of leisure activities according to blood types. It was based on questionnaires answered by 441 collegians in public health departments and 282 in non-public health departments in Daegu Health College in March, 2005. The frequency of leisure activity of once or twice a week or less during weekdays was the most common.: The most common frequencies for all blood types were between 1 and 2 hours on weekdays and between 3 and 5 hours on the weekends or holidays. As far as the type of leisure activities during the weekdays was concerned, in the case of public health departments, blood type A was interested in computer games and then watching TV, blood type B was attracted to watching TV and listening to music, blood type AB was into watching TV, computer games, and listening to music, and blood type O was keen on watching TV and computer games in that order. The type of leisure activity according to blood types in public health departments was shown to be significantly different (p<0.05). The type of future leisure activity was shown to be significantly different between public health departments and non-public health departments (p<0.05). The type of present leisure activity preferred by collegians, according to the study, was entertainment such as computer games for most blood types. The type of future leisure activities was related to the field of tourism and sports. The collegians need to have more advanced and positive leisure activities.

• 한국약용작물학회지
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• 제27권2호
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• pp.108-114
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• 2019

Background: Rutin is decomposed by rutin-degrading enzymes (RDE) during the processing of buckwheat groats, resulting in a decrease in rutin content and a further increase in the bitterness of processed products. Thus, the present study aimed to examine RDE activity in groats and various tissues of domestic buckwheat varieties and to develop a method to reduce the loss of rutin during the groat processing. Methods and Results: RDE activity and isozymes patterns were determined in Tartary and common buckwheat. RDE activity, measured by quercetin production rate, was 273 and $70{\mu}g/g$ fresh weight/min in mature Tartary and common buckwheat groats, respectively. A total of six RDE isozymes were detected in mature groats of Tartary buckwheat on a non-denaturing gel. In Tartary buckwheat groats, RDE activity decreased by approximately 81 or 71% with roasting or steaming for 5 min respectively. As the roasting or steaming time increased to 30 min, RDE activity decreased by over 95%. These results indicated that RDE was inactivated in groats by roasting or steaming. When untreated Tartary buckwheat groats were kneaded with powder, RDE was activated and the quercetin production rate increased by 62%. However, when roasted groats were kneaded with powder, the quercetin production rate decreased by 93%, mainly due mainly to inactivation of RDE, as indicated by a decrease in band intensities of the six isozymes. Conclusions: These results suggested that the loss of rutin, due to RDE activity during processing, may be reduced by 71 to 100% by roasting or steaming groats for 5 to 30 min, due in large part to the inactivation of RDE isozymes.

• 대한의생명과학회지
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• 제10권4호
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• pp.421-427
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• 2004

The possible mechanisms of decreased monoamine oxidase (MAO) A and B activities in cholestatic rat liver were studied. Hepatic and serum MAG activities were determined from the experimental rats with common bile duct ligation (CBDL). The Michaelis-Menten constants in these hepatic enzymes were also measured. The activities of mitochondrial MAO A and B, and mircosomal MAO B as well as their Vmax values were found to be decreased significantly in CBDL plus taurocholic acid (TCA) injected group than in the control group, such as CBDL alone groups. However, their Km values in the experimental groups did not vary. Serum MAO activity increased significantly in the CBDL plus TCA injected group than in the control group. The above results suggest that TCA represses biosynthesis of the MAO in the liver. The elevated activity of the serum MAO is believed to be caused by the increment of membrane permeability ofhepatocytes upon TCA mediated liver cell necrosis.

• Annals of Clinical Neurophysiology
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• 제4권1호
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• pp.7-11
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• 2002

Among drug-induced myopathy, steroids are probably the most common cause. The risk of steroid myopathy(SM) increases with the dose and duration of use. It is typically a proximal myopathy, preferentially affecting the hip girdle muscles. Motor and sensory nerve conduction studies are normal. The needle EMG is usually within the normal range or may be minimally abnormal. Occasionally, low-amplitude, short-duration MUAPs may be seen in the proximal muscles. Of note, abnormal spontaneous activity is not seen. This point is often very useful in differentiating polymyositis(PM) from SM. It is common for patients with PM to be treated with steroids, respond well, and then have the steroids tapered. If muscle weakness then returns, it may be very difficult to differentiate recurrent PM from SM on clinical grounds. The presence of abundant abnormal spontaneous activity strongly suggests PM rather than SM.

• 아태비즈니스연구
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• 제6권2호
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• pp.97-114
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• 2015

This study classify and compare leisure activities migrants women multi-cultural family member includes husband and children. Their common leisure activities is normal daily activity life comparable non leisure daily activity life. Those of common leisure actives is watching type of leisure such as reading book, eat out, visit relatives which reflect passive and egocentric. Therefore need to ownself active, self creative, as well as its family harmony oriented is more signigicant. Future study will be find out the barrier of cultural activities and advanture activities leisure for multi-cultural family.