• 정보처리학회논문지D
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• 제11D권7호
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• pp.1367-1374
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• 2004

XML 트리를 공유하면서 여러 사용자가 동시에 수정할 수 있게 하기 위해서는 부분 트리의 삽입/삭제가 공유될 수 있어야 한다. 이를 위해서는 트리 데이터의 구소 변경 행위에 대한 통시성 제어가 가능해야 한다. 본 논문에서는 DTD 문서 타입 정보를 이용하여 XML 트리의 반복부에 대해서만 부분 트리의 삽입/삭제가 가능한 리스트 데이터 공유 모델을 제안한다. 제안된 리스트 데이터 공유 모델은 구조 변경 행위의 적용 결과가 항상 유효하며, 여러 사용자가 동시에 접근하는 경우에도 문서의 유효성을 보장할 수 있다. 리스트 데이터 공유 모델에서 반복부 자식 노드 리스트를 잠금의 대상으로 하는 리스트 잠금 프로토콜을 제안하였다. 이 잠금 프로토콜은 기존의 방법들과 비교하여 훨씬 간단하면서 적은 수의 잠금 객체만을 다루며, 높은 접근성을 가능하게 한다. 일반적으로 공유되는 XML 트리의 삽입 및 삭제는 흔히 반복부 데이터에 대해서 적용되는 경우가 많으므로 제안된 모델은 터미널 노드 데이터 값에 대한 기존의 접근제어 방법과 함께 사용하였을 때 효과적인 데이터 공유 방법을 제공할 수 있을 것으로 기대된다.

• 대한약리학회지
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• 제22권2호
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• pp.135-143
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• 1986

저자는 적출관류 토끼 신장기능에서 칼슘의 역할과 furosemide의 이뇨작용에 미치는 영향을 관찰하여 다음과 같은 결과를 얻었다. hydralazine놔 verapamil을 주로 신혈관 저항의 감소로 이뇨작용을 나타냈다. furosemide를 hydralazine 또는 verapamil 병합투여시 뚜렷한 이뇨작용이 나타났으며 두군 사이에 차이는 없었다. quinidine은 신혈관 수축을 일으켰으나 이뇨작용이 나타났으며 furosemide의 이뇨작용을 항진시켰다. 칼슘제외된 관류액으로 관류시 칼슘은 신혈관 수축에도 불구하고 이뇨작용이 나타났으며 furosemide의 이뇨작용을 항진시켰다. quinidine은 칼슘이 제외된 상태에서 신장기능 및 furosemide의 이뇨작용에 영향을 미 치지 못하였으나 calcium 병합투여시 과도한 신혈관 수축으로 항 이뇨작용을 보였다. verapamil은 칼슘이 제외된 상태에서 약간의 이뇨작용을 보였지만 칼슘 및 furosemide의 이뇨작용을 변화시키지 못하였다. 이상의 성적은 적출관류 토끼 신장에서 칼슘, verapamil 및quinidine이 이뇨작용이 있으며 칼슘은 furosemide의 이뇨작용을 항진시킨다.

• 복식
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• 제63권3호
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• pp.17-32
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• 2013

This study examined the visual elements of the Trompe l'oeil design and the combination conditions of each element in order to deduce the form generation diagrams of Trompe l'oeil fashion design. The following is what the study found: First, Trompe l'oeil fashion design can be divided into two based on its subject: 'the combination of internal elements of dress' and 'the combination of external elements of dress'. Looking at the visual components of each type, depending on the subject, 'the combination of internal elements of dress' design was achieved by combining internal dress elements: including textile, detail, item, accessory, layering, etc.. In case of 'the combination of external elements of dress' design, the object of Trompe l'oeil was expanded in scope to environment, which includes the actions of a wearer. Second, as for Trompe l'oeil fashion design through the combination of external dress elements, the condition to combined visual components of the work in the process of creation was related to 'the popularity of object', 'the similarity of shapes and sizes', and 'the probability of location'. Third, deriving a form generation diagrams of Trompe l'oeil fashion design was very effective in delineating specific relationships and conditions, directions among elements combined in fashion design.

• Structural Engineering and Mechanics
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• 제52권6호
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• pp.1193-1208
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• 2014

A simulation of failures on responsible elements is only one form of the extreme structural behavior analysis. By understanding the dynamic behavior in incidental situations, it is possible to make a special structural design from the point of the largest axial force, stress and redundancy. The numerical realization of one such simulation analysis was performed using FEM in this paper. The boundary parameters of transient analysis, such as overall structural damping coefficient, load accelerations, time of load fall and internal forces in the responsible structural elements, were determined on the basis of the dynamic experimental parameters. The structure eigenfrequencies were determined in modal analysis. In the study, the basic incidental models were set. The models were identified by many years of monitoring incidental situations and the most frequent human errors in work with heavy structures. The combined load models of structure are defined in the paper since the incidents simply arise as consequences of cumulative errors and failures. A feature of a combined model is that the single incident causes the next incident (consecutive timing) as well as that other simple dynamic actions are simultaneous. The structure was observed in three typical load positions taken from the crane passport (range-load). The obtained dynamic responses indicate the degree of structural sensitivity depending on the character of incident. The dynamic coefficient KD was adopted as a parameter for the evaluation of structural sensitivity.

• Asian Pacific Journal of Cancer Prevention
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• 제15권3호
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• pp.1163-1169
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• 2014

Astragalus, a commonly used traditional Chinese medicine, has exhibited antitumor actions in patients. In this study, in vitro and in vivo antitumor effects of astragalus and synergistic antitumor efficacy in combination with pterostilbene were investigated. Melanoma cells were treated with pterostilbene (Pt), graduated doses of astragalus injection (AI), or these in combination. Cell viability was measured using a MTT assay. Released nucleosomes and caspase activity were measured using enzyme-linked immunosorbent assay. Growth inhibition in vitro and in vivo was also assessed. Analysis of variance and t tests were used for statistical analysis. Significant reduction (p<0.05) in cellular proliferation were observed with AI and AI-Pt in a time- and concentration-dependent manner. Apoptosis and caspase-3/7 activity were significantly increased by AI and AI-Pt treatment (p<0.05). In vivo, AI inhibited melanoma tumor growth, with inhibition rates ranging from 36.5 to 62.3%, by inducing apoptosis via up-regulation Bax expression and the Bax/Bcl-2 ratio and down-regulating Bcl-2 expression. AI significantly inhibits the growth of melanoma in vitro and in vivo by inducing apoptosis. These data suggest that combined treatment of astragalus with pterostilbene enhances antitumor efficacy.

• 한국컴퓨터정보학회논문지
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• 제3권2호
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• pp.209-216
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• 1998

1997년말 이후 한국경제는 U의 유동성조절자금을 지원 받게 되었다. 지원을 받으면서 기업에 대한 경영의 수명성 제고방안으로 기업집단에 결합재무체표를 작성하도록 하였다. 우리나라는 1985년에 연결재무제표를 제정하여 여러차례 수정을 거쳐 지배.종속관계에 있는 기업에 대해서는 연결재무제표를 작성하도록 하고 있다. 그러나 기업구조의 특성으로인하여 연결재무제의 작성과정에서 제도상의 문제와 운용상의 문제가 있었다. 따라서 본고에서는 현재의 연결재무제표의 현황과 문제점을 파거하고 이번에 기업에 파라 결합재무제표를 작성하게될 기업집단 결합재무제표의 내용을 통하여 비교를 한다음 결합재무제표의 도입배경과 그 효과에 대하여 살펴보았다.

• 생약학회지
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• 제16권1호
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• pp.7-11
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• 1985

The extract of Galgun-tang at oral doses of 200 and 400 mg/kg showed remarkable inhibition of 42.5% and 45.0%, respectively, on the carrageenin edema in rat paw. In case of combined oral administration of the extract at each dose of 100, 200 and 400mg/kg with 100mg/kg of aspirin, the inhibitions were 70.5%, 83.6% and 80.7% respectively. These results showed the remarkable effects as compared with those of aspirin which showed 50.3% and 69.4% of inhibition at doses of 100 and 200mg/kg, respectively. On the other hand, on the writhing syndrome in mice induced by 0.7% acetic acid solution, the oral administration of the extract showed remarkable inhibition of 18.5 and 47.7% at doses of 200 and 400mg/kg, respectively. In case of combined oral administration of the extract at each dose of 100, 200 and 400mg/kg with 100mg/kg of aspirin, the inhibition percentages of writhing syndromes were 66.6, 72.3 and 80.8, respectively, whereas the inhibition at doses of 100 and 200mg/kg of aspirin showed 59.9 and 69.5%, respectively.

• Computers and Concrete
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• 제20권1호
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• pp.99-110
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• 2017

Service life assessments which do not include the synergy between mechanical and environmental loading are neglecting a factor that can have a significant impact on structural safety and durability assessment. The degradation of concrete structure is a result of the combined effect of environmental and mechanical factors. In order to make service life design realistic it is necessary to consider both of these factors acting simultaneously. This paper deals with the advanced modelling of concrete carbonation and chloride ingress into concrete using stochastic 1D and 2D models. Widely accepted models incorporated into the new fib Model Code 2010 are extended to include factors that reflect the coupled effects of mechanical and environmental loads on the durability and reliability of reinforced concrete structures. An example of cooling tower degradation by carbonation and an example of a bended reinforced concrete beam kept for several years in salt fog are numerically studied to show the capability of the stochastic approach. The modelled degradation measures are compared with experimental results, leading to good agreement.

• Journal of Ship and Ocean Technology
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• 제3권1호
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• pp.27-41
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• 1999

The objective of the paper is to study the impact of changing the traditional hull design of bulk carriers by providing them with a double hull while keeping the same deadweight. It is demonstrated that by introducing the double hull the structural reliability is increased throughout the entire life and also the extend of the needed repair is reduced. The results are obtained with recently developed mathematical tools for the reliability assessment of ship hulls subjected to the existence of multiple cracks both in the stiffeners and in the plating and it models the crack growth process. The effect of corrosion is represented as time dependent. The long-term stress range acting on the elements is defined as a function of the local transverse pressure of the internal cargo and outside sea water combined with the stresses resulting from the longitudinal bending of the hull, which is a combined with the stresses resulting from the longitudinal bending of the hull, which is a combineation of horizontal and vertical bending moments. The effect of maintenance actions is modelled as a stochastic process. The results show that a different design of the midship section improves the structural safety and also the economy with respect to structural repair of bulk carriers.

• Journal of Plant Biotechnology
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• 제29권3호
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• pp.199-207
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• 2002

The tropane alkaloids hyoscyamine (its racemic form being atropine) and scopolamine are used medicinally as anticholinergic agents that act on the parasympathetic nerve system. Because they differ in their actions on the central nervous system, currently there is a 10-fold higher commercial demand for scopolamine, in the N-butylbromide form, than there is for hyoscyamine and atropine combined. Several solanaceous species have been used as the commercial sources of these alkaloids, but the scopolamine contents in these plants often are much lower than those of hyoscyamine. For this reason there has been long-standing interest in increasing the scopolamine contents of cultivated medicinal plants. Naturally occurring and artificial interspecific hybrids of Duboisia have high scopolamine contents and are cultivated as a commercial source of scopolamine in Australia and other countries. Anther culture combined with conventional interspecific hybridization also has been used to breed high scopolamine-containing plants in the genera Datura and Hyoscyamus, but without much success. The use of recombinant DNA technology for the manipulation of metabolic processes in cells promises to provide important contributions to basic science, agriculture, and medicine. In this review, I introduce on the enzymes and genes involved in tropane alkaloid biosynthesis and current progress in metabolic engineering approaches for tropane alkaloid, especially scopolamine, production.