• The KIPS Transactions:PartD
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• v.11D no.7 s.96
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• pp.1367-1374
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• 2004

For sharing XML data by many users, a way of concurrency and access control is required for isolating update actions such as inserting and deleting subtrees. Exisiting locking mechanisms as 2PL or MGL suffer low concurrency when applied to tree structures. In this paper, list data subtrees model is proposed based on the semantics expressed in DTD. In this model, tree updating actions such as inserting and deleting subtrees are considered only for the repetitive parts of XML trees. The proposed model guarantees that the result XML tree after applying a tree updating action is always valid, even when multiple users access the tree at the same time. Also, a new locking mechanism called list lock-ing protocol is proposed. The new locking protocol is expected to show better accessility with less number of locking objects compared to the Helmer's OO2PL model. Since update actions on a shared XML tree usually applied to the repetitive parts of the tree, the proposed model is expected to provide a useful way for efficient data sharing when combined with previous locking methods on terminal node data.

• The Korean Journal of Pharmacology
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• v.22 no.2
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• pp.135-143
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• 1986

This study was designed to investigate the role of calcium in the function of an isolated perfused rabbit kidney and its effect on the diuretic action of furosemide. The administrations of hydralazine and verapamil produced remarkable diuretic actions mainly by decreasing renal resistance. The administration of furosemide in combination with hydralazine or verapamil produced remarkable diuretic action and there was no difference between the two groups. The administration of quinidine produced a diuretic action in spite of vasoconstriction and potentiated the diuretic action of furosemide. In the calcium-free perfusion medium, the administration of calcium produced a marked diuretic action in spite of vasoconstriction and potentiated significantly the diuretic action of furosemide. The administration of quinidine did not alter renal function and the diuretic action of furosemide, but the combined administration of quinidine and calcium showed antidiuretic effect due to excessive vasoconstriction in the calcium-free perfusion medium. Although the administration of verapamil produced a slight diuretic action in the calcium-free perfusion medium, verapamil did not alter the diuretic action of calcium as well as the diuretic actions of furosemide alone and in combination with calcium. The results of this experiment show that calcium, verapamil and quinidine produced diuretic actions and calcium potentiates the diuretic action of furosemide.

• Journal of the Korean Society of Costume
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• v.63 no.3
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• pp.17-32
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• 2013

This study examined the visual elements of the Trompe l'oeil design and the combination conditions of each element in order to deduce the form generation diagrams of Trompe l'oeil fashion design. The following is what the study found: First, Trompe l'oeil fashion design can be divided into two based on its subject: 'the combination of internal elements of dress' and 'the combination of external elements of dress'. Looking at the visual components of each type, depending on the subject, 'the combination of internal elements of dress' design was achieved by combining internal dress elements: including textile, detail, item, accessory, layering, etc.. In case of 'the combination of external elements of dress' design, the object of Trompe l'oeil was expanded in scope to environment, which includes the actions of a wearer. Second, as for Trompe l'oeil fashion design through the combination of external dress elements, the condition to combined visual components of the work in the process of creation was related to 'the popularity of object', 'the similarity of shapes and sizes', and 'the probability of location'. Third, deriving a form generation diagrams of Trompe l'oeil fashion design was very effective in delineating specific relationships and conditions, directions among elements combined in fashion design.

• Structural Engineering and Mechanics
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• v.52 no.6
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• pp.1193-1208
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• 2014

A simulation of failures on responsible elements is only one form of the extreme structural behavior analysis. By understanding the dynamic behavior in incidental situations, it is possible to make a special structural design from the point of the largest axial force, stress and redundancy. The numerical realization of one such simulation analysis was performed using FEM in this paper. The boundary parameters of transient analysis, such as overall structural damping coefficient, load accelerations, time of load fall and internal forces in the responsible structural elements, were determined on the basis of the dynamic experimental parameters. The structure eigenfrequencies were determined in modal analysis. In the study, the basic incidental models were set. The models were identified by many years of monitoring incidental situations and the most frequent human errors in work with heavy structures. The combined load models of structure are defined in the paper since the incidents simply arise as consequences of cumulative errors and failures. A feature of a combined model is that the single incident causes the next incident (consecutive timing) as well as that other simple dynamic actions are simultaneous. The structure was observed in three typical load positions taken from the crane passport (range-load). The obtained dynamic responses indicate the degree of structural sensitivity depending on the character of incident. The dynamic coefficient KD was adopted as a parameter for the evaluation of structural sensitivity.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.3
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• pp.1163-1169
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• 2014

Astragalus, a commonly used traditional Chinese medicine, has exhibited antitumor actions in patients. In this study, in vitro and in vivo antitumor effects of astragalus and synergistic antitumor efficacy in combination with pterostilbene were investigated. Melanoma cells were treated with pterostilbene (Pt), graduated doses of astragalus injection (AI), or these in combination. Cell viability was measured using a MTT assay. Released nucleosomes and caspase activity were measured using enzyme-linked immunosorbent assay. Growth inhibition in vitro and in vivo was also assessed. Analysis of variance and t tests were used for statistical analysis. Significant reduction (p<0.05) in cellular proliferation were observed with AI and AI-Pt in a time- and concentration-dependent manner. Apoptosis and caspase-3/7 activity were significantly increased by AI and AI-Pt treatment (p<0.05). In vivo, AI inhibited melanoma tumor growth, with inhibition rates ranging from 36.5 to 62.3%, by inducing apoptosis via up-regulation Bax expression and the Bax/Bcl-2 ratio and down-regulating Bcl-2 expression. AI significantly inhibits the growth of melanoma in vitro and in vivo by inducing apoptosis. These data suggest that combined treatment of astragalus with pterostilbene enhances antitumor efficacy.

• Journal of the Korea Society of Computer and Information
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• v.3 no.2
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• pp.209-216
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• 1998

The Korean economy has been under the IMF-led rescue programs since the late 1997. For the transparency of financial currency, Korean government had made the Korean firms which are depend on each other financially compose the consolidated financial statements since 1985, because South Korea's financial crisis has been caused by a string of corporate failures that have put enormous strain on the banking system at a time when the won was plunging against the dollar. But there are many problems to get the transparency in the actions and accountability of both public and private institutions, because of the domestic corporations' structural characteristics and the law of accounting. This paper reviewed, therefore, some problems on the consolidated financial statements and advantages to introducing the combined financial statements through comparing the contents of those statements

• Korean Journal of Pharmacognosy
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• v.16 no.1
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• pp.7-11
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• 1985

The extract of Galgun-tang at oral doses of 200 and 400 mg/kg showed remarkable inhibition of 42.5% and 45.0%, respectively, on the carrageenin edema in rat paw. In case of combined oral administration of the extract at each dose of 100, 200 and 400mg/kg with 100mg/kg of aspirin, the inhibitions were 70.5%, 83.6% and 80.7% respectively. These results showed the remarkable effects as compared with those of aspirin which showed 50.3% and 69.4% of inhibition at doses of 100 and 200mg/kg, respectively. On the other hand, on the writhing syndrome in mice induced by 0.7% acetic acid solution, the oral administration of the extract showed remarkable inhibition of 18.5 and 47.7% at doses of 200 and 400mg/kg, respectively. In case of combined oral administration of the extract at each dose of 100, 200 and 400mg/kg with 100mg/kg of aspirin, the inhibition percentages of writhing syndromes were 66.6, 72.3 and 80.8, respectively, whereas the inhibition at doses of 100 and 200mg/kg of aspirin showed 59.9 and 69.5%, respectively.

• Computers and Concrete
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• v.20 no.1
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• pp.99-110
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• 2017

Service life assessments which do not include the synergy between mechanical and environmental loading are neglecting a factor that can have a significant impact on structural safety and durability assessment. The degradation of concrete structure is a result of the combined effect of environmental and mechanical factors. In order to make service life design realistic it is necessary to consider both of these factors acting simultaneously. This paper deals with the advanced modelling of concrete carbonation and chloride ingress into concrete using stochastic 1D and 2D models. Widely accepted models incorporated into the new fib Model Code 2010 are extended to include factors that reflect the coupled effects of mechanical and environmental loads on the durability and reliability of reinforced concrete structures. An example of cooling tower degradation by carbonation and an example of a bended reinforced concrete beam kept for several years in salt fog are numerically studied to show the capability of the stochastic approach. The modelled degradation measures are compared with experimental results, leading to good agreement.

• Journal of Ship and Ocean Technology
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• v.3 no.1
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• pp.27-41
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• 1999

The objective of the paper is to study the impact of changing the traditional hull design of bulk carriers by providing them with a double hull while keeping the same deadweight. It is demonstrated that by introducing the double hull the structural reliability is increased throughout the entire life and also the extend of the needed repair is reduced. The results are obtained with recently developed mathematical tools for the reliability assessment of ship hulls subjected to the existence of multiple cracks both in the stiffeners and in the plating and it models the crack growth process. The effect of corrosion is represented as time dependent. The long-term stress range acting on the elements is defined as a function of the local transverse pressure of the internal cargo and outside sea water combined with the stresses resulting from the longitudinal bending of the hull, which is a combined with the stresses resulting from the longitudinal bending of the hull, which is a combineation of horizontal and vertical bending moments. The effect of maintenance actions is modelled as a stochastic process. The results show that a different design of the midship section improves the structural safety and also the economy with respect to structural repair of bulk carriers.

• Journal of Plant Biotechnology
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• v.29 no.3
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• pp.199-207
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• 2002

The tropane alkaloids hyoscyamine (its racemic form being atropine) and scopolamine are used medicinally as anticholinergic agents that act on the parasympathetic nerve system. Because they differ in their actions on the central nervous system, currently there is a 10-fold higher commercial demand for scopolamine, in the N-butylbromide form, than there is for hyoscyamine and atropine combined. Several solanaceous species have been used as the commercial sources of these alkaloids, but the scopolamine contents in these plants often are much lower than those of hyoscyamine. For this reason there has been long-standing interest in increasing the scopolamine contents of cultivated medicinal plants. Naturally occurring and artificial interspecific hybrids of Duboisia have high scopolamine contents and are cultivated as a commercial source of scopolamine in Australia and other countries. Anther culture combined with conventional interspecific hybridization also has been used to breed high scopolamine-containing plants in the genera Datura and Hyoscyamus, but without much success. The use of recombinant DNA technology for the manipulation of metabolic processes in cells promises to provide important contributions to basic science, agriculture, and medicine. In this review, I introduce on the enzymes and genes involved in tropane alkaloid biosynthesis and current progress in metabolic engineering approaches for tropane alkaloid, especially scopolamine, production.