• BMB Reports
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• v.51 no.4
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• pp.163-164
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• 2018

CONSTANS (CO) induces the expression of FLOWERING LOCUS T (FT) in the photoperiodic pathway, and thereby regulates the seasonal timing of flowering. CO expression is induced and CO protein is stabilized by FLAVIN-BINDING KELCH REPEAT F-BOX PROTEIN 1 (FKF1) in the late afternoon, while CO is degraded by CONSTITUTIVE PHOTOMORPHOGENIC 1 (COP1) during the night. These regulatory cascades were thought to act independently. In our study, we investigated the relationship between FKF1 and COP1 in the regulation of CO stability in response to ambient light conditions. A genetic analysis revealed that FKF1 acts as a direct upstream negative regulator of COP1, in which cop1 mutation is epistatic to fkf1 mutation in the photoperiodic regulation of flowering. COP1 activity requires the formation of a hetero-tetramer with SUPPRESSOR OF PHYA-105 (SPA1), [$(COP1)_2(SPA1)_2$]. Light-activated FKF1 has an increased binding capacity for COP1, forming a FKF1-COP1 hetero-dimer, and inhibiting COP1 homo-dimerization at its coiled-coil (CC) domain. Mutations in the CC domain result in poor COP1 dimerization and misregulation of photoperiodic floral induction. We propose that FKF1 represses COP1 activity by inhibiting COP1 dimerization in the late afternoon under long-day conditions, resulting in early flowering.

• Proceedings of the Korean Society of Marine Engineers Conference
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• 2001.05a
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• pp.106-111
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• 2001

The performance characteristics of heat pump system using the new refrigerant subcooling system were investigated. The new heat pump system has the ice storage tank to accumulate the latent heat of the refrigerant during the night-time. The heat is released to subcool the saturated refrigerant liquid at the outlet of a condenser in the daytime. The experimental apparatus is a well-instrumented heat pump which consisted of a refrigerant loop and a coolant loop. The test sections(condenser and evaporator) were made of tube-in-tube heat exchanger with the horizontal copper tube of 12.7[mm] outer diameter and 9.5[mm] inner diameter. The evaporating temperatures ranged from $-5[^{\circ}C]$ to $0[^{\circ}C]$ and the subcooling degrees of the refrigerant varied from $15[^{\circ}C]$ to $25[^{\circ}C]$. The test of the ice storage was carried out at evaporating temperature of $-10[^{\circ}C]$ and the ice storage mode is an ice-on-coil type. The main results were summarized as follows ; The refrigerant mass flow rate and compressor shaft power of the heat pump system were independent of the subcooling degrees. The cooling capacity o the heat pump system increases as the evaporating temperature and subcooling degree increases. The cooling capacity of the heat pump system is about 25 to 30% higher than that of normal heat pump system. The COP of the heat pump system which subcooled the refrigerant liquid at the outlet of the condenser is about 28% higher than that of the normal heat pump system.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.24 no.5
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• pp.699-708
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• 2000

To make compact evaporator, experiments that show characteristics of evaporating heat transfer and pressure drop in the helically coiled small diameter tube were taken in this research. The experiments were performed with HCFC-22 in the helically coiled small diameter tube; inner diameter=1.0(mm), tube length=2.0(m), and curvature diameter=31, 34, 46.2(mm). The experiments were also carried out with the following test conditions; saturation pressure=0.588(MPa), mass velocity=$150{\sim}500(kg/m^2s)$, and heat flux=$1{\sim}5(kW/m^2)$. The experiment results are that the empirical correlation to predict heat transfer coefficient for single phase flow in helically coiled small diameter tube was obtained. It was found that dry-out is occurred at low-quality region for evaporation heat transfer because of breaking of annular liquid film. The friction factor of single phase flow of helically coiled tube was agreed with Prandtl's correlation. Finally, It was proposed for correlation that can precisely predict the friction factor of two phase flow of helically coiled tube.

• Investigative Magnetic Resonance Imaging
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• v.20 no.4
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• pp.215-223
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• 2016

Purpose: The management of metal-induced field inhomogeneities is one of the major concerns of distortion-free magnetic resonance images near metallic implants. The recently proposed method called "Slice Encoding for Metal Artifact Correction (SEMAC)" is an effective spin echo pulse sequence of magnetic resonance imaging (MRI) near metallic implants. However, as SEMAC uses the noisy resolved data elements, SEMAC images can have a major problem for improving the signal-to-noise ratio (SNR) without compromising the correction of metal artifacts. To address that issue, this paper presents a novel reconstruction technique for providing an improvement of the SNR in SEMAC images without sacrificing the correction of metal artifacts. Materials and Methods: Low-rank approximation in each coil image is first performed to suppress the noise in the slice direction, because the signal is highly correlated between SEMAC-encoded slices. Secondly, SEMAC images are reconstructed by the best linear unbiased estimator (BLUE), also known as Gauss-Markov or weighted least squares. Noise levels and correlation in the receiver channels are considered for the sake of SNR optimization. To this end, since distorted excitation profiles are sparse, $l_1$ minimization performs well in recovering the sparse distorted excitation profiles and the sparse modeling of our approach offers excellent correction of metal-induced distortions. Results: Three images reconstructed using SEMAC, SEMAC with the conventional two-step noise reduction, and the proposed image denoising for metal MRI exploiting sparsity and low rank approximation algorithm were compared. The proposed algorithm outperformed two methods and produced 119% SNR better than SEMAC and 89% SNR better than SEMAC with the conventional two-step noise reduction. Conclusion: We successfully demonstrated that the proposed, novel algorithm for SEMAC, if compared with conventional de-noising methods, substantially improves SNR and reduces artifacts.

• Journal of the Korean Society of Manufacturing Technology Engineers
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• v.23 no.5
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• pp.456-464
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• 2014

Commercial vehicle drivers typically feel more fatigued compared to general-public drivers. because they spend longer periods of time driving and experience more rough road conditions. This study showed that the application of a magnet, a linear spring, and a seat suspension with nonlinear characteristics was the optimal design to increase comfort while driving. The resonant frequency for the optimal design suspension was 2.8 Hz, and the stiffness was analyzed through displacement-load experiments. Vibration transmissibility was analyzed by suspension stiffness and the existing dynamic compression. The magnetic spring type was at 0.875. As a result, the X-type magnetic spring performed better than the existing spring at 0.729.

• The Korean Journal of Zoology
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• v.38 no.4
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• pp.557-564
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• 1995

The 90 kDa-heat shock protein (HSP90) is one of the major ubiquitous heat shock proteins induced by a vadety of ceilular stresses. HSP90 Is constitutively synthesized even under nonstressed condidons and found In association with several regulatory and structural proteins such as protein kinases and steroid hormone receptors. In the present study, to facilitate its biochemical characterization, HSP90 was pudfied from chick muscle by sequential column chromatography steps including DEAE- cellulose, hydroxyapatite, and Sephacryl S-300 gel filtration and monoclonal antillodies specific to HSP90 were produced by the inurine hybridomal technique. We report the production of 4 posItive hybridoma clones, named as A204, C112, C302 and A204, C112, C302. Among these MoAbs, Cl 12 strongly reconnized chick HSP90 in Western blot and native immunoprocipitation. In addition, C112 showed the crossreactivitles against HSP90 from human, rabbit, mouse, fish and chick but not from Drosophila and E. coil.

• Journal of the Korean Institute of Telematics and Electronics
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• v.17 no.5
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• pp.15-21
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• 1980

An engine control system in which the conventional mechanical ignition system is studied. The contact point of the breaker is replaced by the contactless magnetic pick up sensor from which the information of the speed and the position of the crankshaft is extracted , and further an electronic High Energy Ignitim System Is designed, implemented and tested . The High Energy Igniticwl System increases the secondary spark voltage of the ignition coil from the conventional 10000~15000 volts to the 30000~40000 volts resulting in improving the combustion efficiency. Also, instead of the conventional advimce mechanism forigniliontiming control, a microprocessorbased timinng mechanisn is installed to determine the ignition timing data in response to the engine rpm and the intake manifold vacuum.

• Journal of Sericultural and Entomological Science
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• v.46 no.1
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• pp.28-31
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• 2004

Bombyx mori silk fibroin/hyaluronic acid blend films were prepared by mixing aqueous solution of B. mori silk fibroin and hyaluronic acid. According to the FTIR spectra, no interaction between silk fibroin and hyaluronic acid was found. The conformation of silk fibroin in blend films was changed from random coil to $\beta$-sheet structure by treatment of EDC ethanol solution. Thermal degradation peak of silk fibroin and hyaluronic acid was also not altered by blending each other. The average swelling ratio of silk fibroin/hyaluronic acid blend films was 70. Therefore, silk fibroin/hyaluronic acid blend films might be one of possible wound dressing materials.

• Annals of Clinical Neurophysiology
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• v.5 no.2
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• pp.187-191
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• 2003

Purpose: MEPs elicited by transmagnetic stimulations of the motor cortex are facilitated by voluntary muscle contraction. We evaluated the effects of the imagination of the movements on latencies of MEPs and reciprocal inhibition by using transmagnetic stimulations. Methods: Twenty two healthy volunteers(eight men and fourteen women) were studied. TMSs were delivered at rest and during imagining abducting or adducting right thumb. A stimulator with a round coil and a fixed intensity of 80% of maximum was used to evoke MEPs. MEPs were evoked by magnetic stimulations over the scalp and cervical spine(C7-T1), and central motor conduction times(CMCT) were calculated by subtracting the latency of compound muscle action potentials(CMAPs) obtained by stimulating over the cervical spine from that obtained by stimulating over the scalp. The motor evoked potentials were recorded from right abductor pollicis brevis muscle(APB) and adductor pollicis muscle(AP) simultaneously. Results: Imagination of abduction resulted in a shortened latency of the CMAPs in APB, and a prolonged latency in AP. Imagination of adduction resulted in a shortened latency in AP, and a prolonged latency in APB. But the imagination caused no significant change in the latency of CMAPs elicited by stimulation over cervical spine. Therefore, the changes of the CMCTs account for these latency changes with imagination of movement. With the imagination of abduction, there are significant reduction of the CMCT's in APB(10.8%) and prolongation in AP(5.8%). On the other hand, with the imagination of adduction, prolongation of the CMCT's in APB(7.3%) and reduction in AP(5.9%) were observed. Conclusion: These findings indicate that imagination of muscle contraction increases the excitability of the human corticospinal system. Reciprocal inhibition may be accountable for the prolonged latency in the antagonist muscle.

• Journal of the Korean Magnetics Society
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• v.14 no.6
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• pp.201-206
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• 2004

The AC-DC magnetic field standard systems were constructed for the calibration of magnetometers for low magnetic field and the tests for low magnetic field characteristics of sensors and materials. In the range of 1 mT, the expanded uncertainty of dc is 8${\times}$10$\^$-6/, ac uncertainties are 0.16% in 0.1～1 kHz, 0.26% in 1～5 kHz, and 0.44% in 5～20 kHz. We have been participated in international key comparison(KC) to achieve the equality and the mutual agreement between standard institutes for the results of calibrations and tests. KRISS participating in ac-dc magnetic flux density of KC got equal level of uncertainty results compare with the advanced nations. It confirm that measurement ability of magnetic flux density is high level in the world.