• Title/Summary/Keyword: coding method

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Workflow for Building a Draft Genome Assembly using Public-domain Tools: Toxocara canis as a Case Study (개 회충 게놈 응용 사례에서 공개용 분석 툴을 사용한 드래프트 게놈 어셈블리 생성)

  • Won, JungIm;Kong, JinHwa;Huh, Sun;Yoon, JeeHee
    • KIISE Transactions on Computing Practices
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    • v.20 no.9
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    • pp.513-518
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    • 2014
  • It has become possible for small scale laboratories to interpret large scale genomic DNA, thanks to the reduction of the sequencing cost by the development of next generation sequencing (NGS). De novo assembly is a method which creates a putative original sequence by reconstructing reads without using a reference sequence. There have been various study results on de novo assembly, however, it is still difficult to get the desired results even by using the same assembly procedures and the analysis tools which were suggested in the studies reported. This is mainly because there are no specific guidelines for the assembly procedures or know-hows for the use of such analysis tools. In this study, to resolve these problems, we introduce steps to finding whole genome of an unknown DNA via NGS technology and de novo assembly, while providing the pros and cons of the various analysis tools used in each step. We used 350Mbp of Toxocara canis DNA as an application case for the detailed explanations of each stated step. We also extend our works for prediction of protein-coding genes and their functions from the draft genome sequence by comparing its homology with reference sequences of other nematodes.

Secure JPEG2000 Steganography by the Minimization of Code-block Noise Variance Changes (코드블록 노이즈 분산의 변화를 최소화하는 안전한 JPEG2000 스테가노그라피)

  • Yoon, Sang-Moon;Lee, Hae-Yeoun;Joo, Jeong-Chun;Bui, Cong-Nguyen;Lee, Heung-Kyu
    • The KIPS Transactions:PartC
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    • v.15C no.3
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    • pp.149-156
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    • 2008
  • JPEG2000 is the upcoming image coding standard that provides better compression rate and image quality compared with JPEG. Lazy-mode steganography guarantees the safe communication under the two information loss stages in JPEG2000. However, it causes the severe changes of the code-block noise variance sequence after embedding and that is detectable under the steganalysis using the Hilbert-Huang transform (HHT) based sequential analysis. In this paper, a JPEG2000 lazy-mode steganography method is presented. The code blocks which produce the sudden variation of the noise variance after embedding are estimated by calculating low precision code-block variance (LPV) and low precision code-block noise variance (LPNV). By avoiding those code-blocks from embedding, our algorithm preserves the sequence and makes stego images secure under the HHT-based steganalytic detection. In addition, it prevents a severe degradation of image quality by using JPEG2000 quality layer information. On various 2048 images, experiments are performed to show the effective reduction of the noise variation after message embedding and the stable performance against HHT-based steganalysis.

Demographic Characteristics and Exposure Assessment for Applicants Who Have Been Injured by Humidifier Disinfectant - Focusing on 4-1 and 4-2 Applicants - (가습기살균제 피해 신청자들의 인구학적 특성 및 노출평가 - 4-1차와 4-2차 신청자를 중심으로 -)

  • Choi, Yoon-Hyeong;Ryu, Hyeonsu;Yoon, Jeonggyo;Lee, Seula;Kwak, Jung Hyun;Han, Bo-Young;Chu, Yeon-Hee;Kim, Pan-Gyi;Yang, Wonho
    • Journal of Environmental Health Sciences
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    • v.44 no.4
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    • pp.301-314
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    • 2018
  • Objectives: The aim of this study was to introduce the overall progress of exposure assessment to humidifier disinfectant (HD); to present participants' demographic characteristics, exposure characteristics to humidifier disinfectant, and exposure classification; and furthermore to compare those characteristics between survivors and non-survivors. Methods: An assessment of environmental exposure to HD was conducted using modified HD-specific questionnaires that had been previously validated. We analyzed the data from 4,482 participants who had been potentially exposed to HD and had registered with the KEITI (Korea Environmental Industry & Technology Institute) from September 2016 to May 2018 (the fourth survey). Environmental exposure assessments were performed as follows: 1) contact with participants, 2) environmental exposure assessment though face-to-face interviews, 3) assessment review and coding, and 4) exposure rating. Results: Overall, survivors made up 77.1% (3,457 subjects) and non-survivors made up 22.9% (1,025 subjects). When compared with the survivors, non-survivors had a higher proportion of subjects aged >60 years and subjects who answered as suffering lung damage and having purchased HD because it is "Beneficial to health" (p<0.05). For the exposure characteristics compared to survivors, non-survivors had a higher proportion of cases of distance from humidifier to face being less that one meter and the spray direction being toward the face (p<0.05). Overall, respondents who used the "Oxy Ssak Ssak New Gaseupgi Dangbun", "Aekyung Gaseupgi Mate", "Homeplus Gaseupgi Chungjungje", and "E-Mart Gaseupgi Salgyunje" products made up 66.1, 12.3, 4.0, and 3.6%, respectively, and 72.5% of respondents used products with PHMG as the active chemical. When compared with survivors, non-survivors had a higher proportion of use of "Oxy Ssak Ssak New Gaseupgi Dangbun" but a lower proportion of use of products with CMIT/MIT, PGH, or PHMG as the active chemical. Conclusions: This study provided demographic characteristics and exposure assessment for applicants who have been injured by HD. In spite of the limitations of performing past exposure assessment through a questionnaire survey, such as recall bias, useful results may be obtained by comparing survivors with non-survivors. Further studies such as the exposure rating method and so on are necessary to assess past exposure to HD.

The Generating Processes of Scientific Emotion in the Generation of Biological Hypotheses (생물학 가설의 생성에서 나타난 과학적 감성의 생성 과정)

  • Kwon, Yong-Ju;Shin, Dong-Hoon;Park, Ji-Young
    • Journal of The Korean Association For Science Education
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    • v.25 no.4
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    • pp.503-513
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    • 2005
  • The purpose of this study was to analyze the generating processes of scientific emotion, that appears during the generation of biological hypotheses. To perform the study, a tentative model was set up through pilot test, a think-aloud training procedure was planned and a standardized interview instrument was developed before getting protocols. In this study, 8 college students were selected to bring out protocol through the method of think-aloud, retrospective debriefing, focused interview and observing. As the result of analysis of the collected protocol through coding scheme, 4 types of process for scientific emotion-generating were sorted out. First type was a basic process which was a feeling process in prior to recognition. Second type was a retrospective process that explains the process of retrospect for emotional memory based on the past. Third type was a cognitive process and it explains emotion that occurs during thinking process to achieve cognitive goal. Fourth type was an attribution process and it explains that emotion is generated in the process of attribution for cognitive goal's achievement. These types of process of scientific emotion-generating can contribute the basis for developing cognitive model of EBL (Emotional Brain-based Learning) strategy.

Study on School Teachers' Perception of and Usage of SMART Education (스마트교육에 대한 교사의 인식 및 활용 실태)

  • Suh, Soonshik;Goh, Yuha
    • Journal of The Korean Association of Information Education
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    • v.20 no.2
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    • pp.139-150
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    • 2016
  • The development of Smart devices has become a key influence on the changes of the school system. As Smart education is integrated and institutionalized in school systems, how it is perceived and utilized by teachers should be investigated. This study is conducted to find out the perception of the teachers on characteristics of Smart education, using qualitative research method, and to analyze importance-performance, using additional quantitative analysis. To figure out the perceptions of the attributes of Smart education by teachers, related literatures were reviewed. The 8 teachers were selected and the data on their perceptions of Smart education were collected through direct observation of class and semi-structured in-depth interview. After researching, we finally drew out 16 final concepts, 6 sub-categories, and 3 categories in the open coding process. Based on the 16 concepts on teachers' perceptions on Smart education, importance-performance analysis (IPA) were conducted to identify areas that need focus and improvement. Based on the results of teachers' perceptions on importance of and the levels of use of Smart education, recommendations were provided for better practice of Smart education in school.

The Difference of Gestures between Scientists and Middle School Students in Scientific Discourse: Focus on Molecular Movement and the Change in State of Material (과학담화에서 과학자와 중학생의 제스처 비교 -분자운동과 물질의 상태변화를 중심으로-)

  • Kim, Ji Hyeon;Cho, Hae Ree;Cho, Young Hoan;Jeong, Dae Hong
    • Journal of The Korean Association For Science Education
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    • v.38 no.2
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    • pp.273-291
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    • 2018
  • Gestures accompanied by scientific discourses play an important role in constructing mental models and making model-based inferences. According to embodied cognition literature, gestures can be a source of recognition of the mental models of students and help them in changing naive beliefs about science. This study intends to compare the gestures of scientists with that of middle school students in explaining scientific phenomena and to explore the relationship between gestures and scientific discourse. In the study, 10 scientists and 10 middle school students participated in clinical interviews and the tests of knowledge and self-efficacy. Participants engaged in one-on-one clinical interviews with semi-structured questions about three tasks regarding the molecular movement and the state change of matter. Four researchers carried out open coding and applied a constant comparison method in order to analyze video-recorded gestures. This study found four themes (feature of gesture, use of gesture, content of gesture, function of gesture) about the differences of gestures between scientists and middle school students. Scientists used more diverse and elaborate gestures systematically and frequently in the interview. Although students used gestures in their scientific talk and reasoning, the gestures of students were not well grounded on scientific knowledge and had different functions from those of scientists. The findings revealed that gestures can represent underlying cognition and strengthen scientific thinking. We should encourage students to use gestures as a tool to understand scientific concepts and make inferences.

Implementation of Stopping Criterion Algorithm using Variance Values of LLR in Turbo Code (터보부호에서 LLR 분산값을 이용한 반복중단 알고리즘 구현)

  • Jeong Dae-Ho;Kim Hwan-Yong
    • Journal of the Institute of Electronics Engineers of Korea TC
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    • v.43 no.9 s.351
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    • pp.149-157
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    • 2006
  • Turbo code, a kind of error correction coding technique, has been used in the field of digital mobile communication system. As the number of iterations increases, it can achieves remarkable BER performance over AWGN channel environment. However, if the number of iterations is increased in the several channel environments, any further iteration results in very little improvement, and requires much delay and computation in proportion to the number of iterations. To solve this problems, it is necessary to device an efficient criterion to stop the iteration process and prevent unnecessary delay and computation. In this paper, it proposes an efficient and simple criterion for stopping the iteration process in turbo decoding. By using variance values of LLR in turbo decoder, the proposed algerian can largely reduce the average number of iterations without BER performance degradation in all SNR regions. As a result of simulation, the average number of iterations in the upper SNR region is reduced by about $34.66%{\sim}41.33%$ compared to method using variance values of extrinsic information. the average number of iterations in the lower SNR region is reduced by about $13.93%{\sim}14.45%$ compared to CE algorithm and about $13.23%{\sim}14.26%$ compared to SDR algorithm.

Comparative Analysis of Local Green Tea in Korea by STS-RFLP (STS-RFLP법을 이용한 국내지역 재배녹차의 비교분석)

  • Cho, Kiu-Hyung;Jo, Aruna;Tsuge, Tomohiko;Kim, Jong-Cheol;Kim, Ru-Mi;Yoon, Ho-Sung;Kim, Gyung-Tae
    • Journal of Life Science
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    • v.20 no.9
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    • pp.1415-1419
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    • 2010
  • Consumption of green tea has increased along with increasing concern regarding healthier lifestyles, and many brands of green tea are sold with a label indicating the region of Korea in which the tea was produced. However, there is little information on identifying the difference between the green tea cultivars according to the region they were grown. Here, 9 green tea cultivars collected from Hadong region, Bosung region, China and Japan were subjected to the STS-RFLP analysis. Using the coding and noncoding DNA regions of genes related to the phenylpropanoid pathway, such as phenylalanine ammonia-lyase, chalcone synthase and dihydroflavonol 4-reductase, we have identified the differences between green tea cultivars according to the region they were grown in. In this study, we showed a STS-RFLP method of green tea analysis which easily distinguished different kinds of tea using the primers as described. In addition, we identified that the green tea cultivars from Hadong and Bosung displayed a different profile when PAL intron was digested with Dde I, suggesting that a rapid authentication system for green tea cultivars grown in different regions in Korea is available.

Radix-4 Trellis Parallel Architecture and Trace Back Viterbi Decoder with Backward State Transition Control (Radix-4 트렐리스 병렬구조 및 역방향 상태천이의 제어에 의한 역추적 비터비 디코더)

  • 정차근
    • Journal of the Institute of Electronics Engineers of Korea SP
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    • v.40 no.5
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    • pp.397-409
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    • 2003
  • This paper describes an implementation of radix-4 trellis parallel architecture and backward state transition control trace back Viterbi decoder, and presents the application results to high speed wireless LAN. The radix-4 parallelized architecture Vietrbi decoder can not only improve the throughput with simple structure, but also have small processing delay time and overhead circuit compared to M-step trellis architecture one. Based on these features, this paper addresses a novel Viterbi decoder which is composed of branch metric computation, architecture of ACS and trace back decoding by sequential control of backward state transition for the implementation of radix-4 trellis parallelized structure. With the proposed architecture, the decoding of variable code rate due to puncturing the base code can easily be implemented by the unified Viterbi decoder. Moreover, any additional circuit and/or peripheral control logic are not required in the proposed decoder architecture. The trace back decoding scheme with backward state transition control can carry out the sequential decoding according to ACS cycle clock without additional circuit for survivor memory control. In order to evaluate the usefulness, the proposed method is applied to channel CODEC of the IEEE 802.11a high speed wireless LAN, and HDL coding simulation results are presented.

A VLSI Design of High Performance H.264 CAVLC Decoder Using Pipeline Stage Optimization (파이프라인 최적화를 통한 고성능 H.264 CAVLC 복호기의 VLSI 설계)

  • Lee, Byung-Yup;Ryoo, Kwang-Ki
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.46 no.12
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    • pp.50-57
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    • 2009
  • This paper proposes a VLSI architecture of CAVLC hardware decoder which is a tool eliminating statistical redundancy in H.264/AVC video compression. The previous CAVLC hardware decoder used four stages to decode five code symbols. The previous CAVLC hardware architectures decreased decoding performance because there was an unnecessary idle cycle in between state transitions. Likewise, the computation of valid bit length includes an unnecessary idle cycle. This paper proposes hardware architecture to eliminate the idle cycle efficiently. Two methods are applied to the architecture. One is a method which eliminates an unnecessary things of buffers storing decoded codes and then makes efficient pipeline architecture. The other one is a shifter control to simplify operations and controls in the process of calculating valid bit length. The experimental result shows that the proposed architecture needs only 89 cycle in average for one macroblock decoding. This architecture improves the performance by about 29% than previous designs. The synthesis result shows that the design achieves the maximum operating frequency at 140Mhz and the hardware cost is about 11.5K under a 0.18um CMOS process. Comparing with the previous design, it can achieve low-power operation because this design is implemented with high throughputs and low gate count.