• Title/Summary/Keyword: clinical indicator

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Anesthetic efficacy of Gow-Gates versus inferior alveolar nerve block for irreversible pulpitis: a systematic quantitative review

  • Sarfaraz, Ifrah;Pascoal, Selma;Macedo, Jose Paulo;Salgado, Abel;Rasheed, Dil;Pereira, Jorge
    • Journal of Dental Anesthesia and Pain Medicine
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    • v.21 no.4
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    • pp.269-282
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    • 2021
  • This review aimed to assess and compare the outcomes of the anesthetic efficacy of inferior alveolar nerve block (IANB) and Gow-Gates mandibular nerve block (GGMNB) in patients with symptomatic irreversible pulpitis. A descriptive systematic review of quantitative research was conducted wherein the "Preferred Reporting Items for Systematic Reviews (PRISMA)" was adopted, and the Problem/Patient/Population, Intervention/Indicator, Comparison, Outcome (PICO) criteria were used to structure the research question. A literature search was performed using PubMed/Medline, Cochrane Library, Google Scholar, and Ovid. Selection criteria were applied for populations over nine years of age, of either sex, with irreversible pulpitis, and articles published in English regarding conventional IANB or IANB and Gow-Gates techniques between 2009 and 2019. Prospective randomized clinical trials or randomized controlled trials were included in the review, in which anesthetic efficacy or success was measured. After screening, four articles were included. Three studies were randomized clinical trials, and two were randomized controlled trials. The validity and reliability of the individual studies were examined. There was evidence of the higher efficacy of the GGMNB technique than that of the IANB technique. However, both techniques can be mastered through training.

Confirmed cases of severe fever with thrombocytopenia syndrome in companion cats with a history of tick exposure in the Republic of Korea

  • Sun-Woo, Han;Ju-Hyun, An;Ji-Min, Rim;Eunseok, Jeong;Sungjun, Noh;Myoungdai, Kang;Jun-Gu, Kang;Joon-Seok, Chae
    • Journal of Veterinary Science
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    • v.23 no.6
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    • pp.83.1-83.7
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    • 2022
  • Severe fever with thrombocytopenia syndrome (SFTS) is a zoonotic disease, and its clinical information and prevalence are important. This study was conducted on 22 feline patients from the Republic of Korea (ROK), suspected to suffer from a tick-borne disease. Four cats were positive for SFTS, and genotypes B-1, B-3, D, and F were identified. Clinical symptoms, such as anorexia, jaundice, thrombocytopenia, leukopenia, and hyperbilirubinemia, were detected. This is the first report of SFTS virus genotypes B-1, D, and F from cats in the ROK. Moreover, our results suggest that jaundice may be an indicator of SFTS in cats.

Application of AIG Implemented within CLASS Software for Generating Cognitive Test Item Models

  • SA, Seungyeon;RYOO, Hyun Suk;RYOO, Ji Hoon
    • Educational Technology International
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    • v.23 no.2
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    • pp.157-181
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    • 2022
  • Scale scores for cognitive domains have been used as an important indicator for both academic achievement and clinical diagnosis. For example, in education, Cognitive Abilities Test (CogAT) has been used to measure student's capability in academic learning. In a clinical setting, Cognitive Impairment Screening Test utilizes items measuring cognitive ability as a dementia screening test. We demonstrated a procedure of generating cognitive ability test items similar as in CogAT but the theory associated with the generation is totally different. When creating cognitive test items, we applied automatic item generation (AIG) that reduces errors in predictions of cognitive ability but attains higher reliability. We selected two cognitive ability test items, categorized as a time estimation item for measuring quantitative reasoning and a paper-folding item for measuring visualization. As CogAT has widely used as a cognitive measurement test, developing an AIG-based cognitive test items will greatly contribute to education field. Since CLASS is the only LMS including AIG technology, we used it for the AIG software to construct item models. The purpose of this study is to demonstrate the item generation process using AIG implemented within CLASS, along with proving quantitative and qualitative strengths of AIG. In result, we confirmed that more than 10,000 items could be made by a single item model in the quantitative aspect and the validity of items could be assured by the procedure based on ECD and AE in the qualitative aspect. This reliable item generation process based on item models would be the key of developing accurate cognitive measurement tests.

The Effect of Using a Assistant Pad when Doing Chest Compression During Cardiopulmonary Resuscitation

  • Yun, Seong-Woo
    • Journal of the Korea Society of Computer and Information
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    • v.22 no.2
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    • pp.105-110
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    • 2017
  • We propose a effectiveness of the assistant pad during cardiopulmonary resuscitation and provide basic data for high quality cardiopulmonary resuscitation. The subjects of the study were 28 students in the emergency department who completed the BLS Health Care-Provider under the experimental study by the randomized crossover design. Data were analyzed by using SPSS 20.0 Version. The results of this study showed that chest compressions using assistant pads decreased pain and fatigue than normal chest compressions, and the depth of chest compressions was deeper than normal depth. The results of this study shows that the use of assistant pads between the one hand and the other hand during cardiopulmonary resuscitation may increase accuracy and depth were improved. Therefore intensive indicator also improved. However, with regard to the use of assistant pads, further studies will be needed to identify the potential for clinical use.

In vitro study of downstream flow passing through heart valve prostheses (인공 심장판막 하류 유동의 in vitro 연구)

  • Kim Hyoung-Bum;Lanning Craig
    • Journal of the Korean Society of Visualization
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    • v.4 no.1
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    • pp.47-55
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    • 2006
  • The left ventricular filling flow is now considered as an indicator which can be used for early diagnosing of cardiovascular diseases. Because the understanding of left ventricular flow physics is critical for this purpose, the downstream flow characteristics of the artificial heart valve are investigated using particle image velocimetry (PIV) method. In this study, we investigated the wake characteristics of flows passing through three different artificial valves (St.Jude medical bileaflet mechanical valve. Bjork-Shiley monostrut mechanical valve and St.Jude medical Biocor bio valve). The downstream flow field has remarkably altered according to the different valves. SJM MHV has the flow field similar to the pulsating circular jet and BS MHV has oblique pulsating jet. SJM BHV shows the similar flow field of clinical data of normal heart.

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Surface EMG Amplitude Estimation by using Spike and Turn Variables (Spike와 Turn 변수를 이용한 표면근전도 신호의 진폭 추정)

  • Lee, Jin
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.67 no.1
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    • pp.124-130
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    • 2018
  • The EMG amplitude estimator, which has been investigated as an indicator of muscle force, is of high relevance not only in biomechanical studies but also more and more in clinical applications. This paper presents a new approach to estimate surface EMG amplitude by using the mean spike and mean turn amplitude(MSA and MTA) variables. Surface EMG signals, a total of 198 signals, were recorded from biceps brachii muscle over the range of 20-80%MVC isometric contraction and performance of the MSA and MTA variables applied to amplitude estimation of the EMG signals were investigated. To examine the performance, a SNR(signal-to-noise ratio) was computed from each amplitude estimate. The results of the study indicate that MSA and MTA amplitude estimations with first order whitening filter and 300[ms]-350[ms] moving average window length are optimal and show better performance(mean SNR improvement of 6%-15%) than the most frequently used variables(ARV and RMS).

The Human Sperm Zona-Free Hamster Ovum Penetration Assay as a Prognostic Indicator in a Human In-vitro Fertilization Program (체외수정의 예후지표로서 정자의 Zona-Free Hamster Ovum Penetration 분석에 관한 연구)

  • Hwang, Dong-Hoon;Lee, Yoon-Ho
    • Clinical and Experimental Reproductive Medicine
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    • v.16 no.2
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    • pp.173-177
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    • 1989
  • Defective or inadequate semen quality, usually presenting as low sperm count or poor sperm motility , is recognizable by semen analysis. However, the ability of spermatozoa to fertilize an ovum is not determined used in various experiments. In this study, hamster oocyte sperm penetration assay was used to determine the fertilizing capacity of sperms in 20 subjects which divided into two groups, group A with 10 normal fertile men, and group B with 10 infertile men. The % penetration in group A and group B were 61% and 35% respectively, which showed statistically not significant but fertilization index was significantly different between group A(FI=2.24) and group B(FI=O.05). Additionally it seemed that the percentage of sperm penetraton was influenced more by the motility of spermatozoa than by the number.

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Flow Velocity Changes of Carotid, Axillary, Brachial and Radial Artery after Stellate Ganglion Block (성상신경절 차단후 총경동맥, 액와동맥, 상완동맥, 요골동맥의 혈류속도변화)

  • Seo, Young-Sun
    • The Korean Journal of Pain
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    • v.8 no.1
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    • pp.55-59
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    • 1995
  • Stellate ganglion block (SGB) is applicated frequently to increase the blood flow and to reduce the pain in head, neck and upper extremity. The effects of SGB are able to be estimated by clinical signs and symptoms of Horner's syndrome, skin warmth, anhydrosis, etc. The effects are also estimated by sympathetic function and the blood flow. Blood flow velocities and pulsatility indices of common carotid,d axillary, brachial and radial artery were measured by Doppler flowmeter after SGB with 1% lidocaine at C6 level. Blood velocities of all arteries were increased and pulsatility indices of all arteries were decreased. This results suggest that SGB increase the blood flow of head and upper extremity and Doppler flowmeter is a good indicator of the effects of SGB.

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Ginseng Extract Protects Unsaturated Fatty acid from Decomposition Caused by Iron-Mediated Lipid Peroxidation

  • Okada, Shi-Geru;Zhang, Da-Xian
    • Proceedings of the Ginseng society Conference
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    • 1998.06a
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    • pp.57-62
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    • 1998
  • We hypothesized the primary effect of ginseng was to protect cell membrane fatty acids from decomposition caused by free radicals. To confirm the antioxidant effect of ginseng, we measured the inhibitory effect on the formation of thiobarbituric acid-reactive substances, an indicator of lipid peroxidation, and evaluated the free radical scavenging effect of ginseng by electron spin resonance spectrometer, and gas chromatography. The results showed that thiobarbituric acid-reactive substances formed and the loss of arachidonic acid during lipid peroxidation, and that hydroxyl (-like) radical peak formed by the iron complex (ferric nitrilotriacetate, an known free radical generator in vitro) were completely inhibited by ginseng extract. This antioxidant effect of ginseng may be responsible for its wide pharmacological actions in clinical practice. As the free radical reactions in general are rapid and non-specific, ginseng seems to act as a normalizer, rather than a general tonic, at the stages of acute or chronic active phase of the various diseases.

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Highly purified chitosan reduce blood alcohol concentration, aspartate aminotransferase, and alanine aminotransferase levels in human

  • Chung, Hwan-Suck;Koo, Hyun-Na;Moon, Young-Hoe;Kim, Hyung-Min
    • Advances in Traditional Medicine
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    • v.3 no.1
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    • pp.18-20
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    • 2003
  • The purpose of this study was to examine the effect of supplementary highly purified chitosan (HPC) on blood alcohol concentration in healthy human. The human study was performed with two sections. Each section of the study was conducted by two-phase cross-over design with a week wash-out period. All volunteers took HPC in one phase, and took a placebo in the next phase. Blood alcohol concentrations were different between in those taking HPC and in those taking the placebo in the human. And the concentration of serum aspartate aminotransferase (AST, GOT) and alanine aminotransferase (ALT, GPT), the indicator of liver cell damage, was lowered in those taking HPC, compared to those taking the placebo. In conclusion, taking HPC prior to drinking alcohol can somewhat reduce alcohol concentration in human blood and liver cell damage.