Clinical and Experimental Reproductive Medicine

The Korean Society for Reproductive Medicine (대한생식의학회)
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The Human Sperm Zona-Free Hamster Ovum Penetration Assay as a Prognostic Indicator in a Human In-vitro Fertilization Program

체외수정의 예후지표로서 정자의 Zona-Free Hamster Ovum Penetration 분석에 관한 연구

  • Hwang, Dong-Hoon (Department of Obstetrics and Gynecology, College of Medicine, Yonsei University) ;
  • Lee, Yoon-Ho (Department of Obstetrics and Gynecology, College of Medicine, Yonsei University)
  • 황동훈 (연세대학교 의과대학 산부인과학교실) ;
  • 이윤호 (연세대학교 의과대학 산부인과학교실)
  • Published : 1989.12.30
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Abstract

Defective or inadequate semen quality, usually presenting as low sperm count or poor sperm motility , is recognizable by semen analysis. However, the ability of spermatozoa to fertilize an ovum is not determined used in various experiments. In this study, hamster oocyte sperm penetration assay was used to determine the fertilizing capacity of sperms in 20 subjects which divided into two groups, group A with 10 normal fertile men, and group B with 10 infertile men. The % penetration in group A and group B were 61% and 35% respectively, which showed statistically not significant but fertilization index was significantly different between group A(FI=2.24) and group B(FI=O.05). Additionally it seemed that the percentage of sperm penetraton was influenced more by the motility of spermatozoa than by the number.

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