• Asian-Australasian Journal of Animal Sciences
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• 제20권5호
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• pp.795-801
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• 2007

Patients with Type I diabetes mellitus have been treated with porcine insulin for several decades and pigs have recently been deemed an ideal source of microencapsulated islet cells for clinical xenotransplantation. In this study, neonatal pigs were anesthetized and sacrificed prior to a pancreatectomy. Islet cells were isolated from pancreas via collagenase digestion. Islet cells were separated and collected by hand under microscopic guidance. These cells were suspended in 1.4% sodium alginate solution and encapsulated by dropping them into 1.1% calcium chloride solution and in which the round gel in size was 250-400 ${\mu}m$ in diameter. Viability of the microencapsulated islet cells cultured in medium at $37^{\circ}C$ was assessed by MTT assay. Furthermore, insulin released in response to glucose challenge was investigated using an enzyme-linked immunosorbent assay. Secretion of insulin was low in response to the basal glucose solution (4.4 mM) in medium and was significantly higher in response to the high glucose solution (16.7 mM). The viability of microencapsulated islet cells did not differ significantly over a period of 7 days; that is, the increasing pattern of insulin concentration in the culture medium after glucose stimulation interval day was similar throughout the 7 days cultivation. In summary, experimental evidences indicated that the effects of alginate-microencapsulation prolonged survival of the neonatal porcine islets in vitro cultures and the insulin response to glucose of the islets was maintained.

• The Korean Journal of Pain
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• 제21권1호
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• pp.57-61
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• 2008

Background: Shoulder joint injection is currently performed under fluoroscopic or computed tomography scan guidance. We performed this study to determine if an ultrasound guided shoulder joint injection through rotator cuff interval would have clinical usefulness. Methods: A total of 17 volunteers [12 women, 5 men; mean age 28 yr (23-32 yr)] received shoulder joint injection under multilinear ultrasound (5-10 MHz). Volunteers were positioned supinely on a table with their arm in a neutral position. The anterior shoulder region of the patient was sterilized using povidone iodine. A 24 gauge needle was introduced and directly visualized in real time as it passed obliquely from the skin surface to the inferior space of the biceps tendon. If there was little or no resistance to the injection, a contrast media (omnipaque) was injected and checked fluoroscopically. Results: Ultrasound guided shoulder joint injection through rotator cuff interval was successful in all cases. The average time taken for the procedure was $27.5{\pm}16.5sec$. The vertical distance from skin to the inferior space of the biceps tendon was $1.6{\pm}0.4cm$ and the distance of needle from the skin to the inferior space of biceps tendon was $2.8{\pm}0.6cm$. The procedure was well tolerated by all volunteers. Conclusions: Ultrasound guided shoulder joint injection through rotator cuff interval is an effective, rapid, and easy-to-perform injection technique. Ultrasound guided injection enables exact needle placement and avoids the use of both ionizing radiation and iodinated contrast material.

• 대한의용생체공학회:의공학회지
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• 제38권3호
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• pp.102-110
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• 2017

본 논문은 자석을 회전시켜 실시간으로 자기장을 변화시키고 그로 인해 특정 조건에서 산화철 나노입자를 side point(피부)보다 center point(심부)에서 더 많이 유도할 수 있다는 가능성을 제시하였다. 향후 연구로 유속에 따른 Critical Magnetic flux density, 시간에 따른 나노입자 축적량, 자기장과 산화철 나노입자의 상호작용을 고려한 실험 설계, 전자석 등을 이용한 자기장조절을 연구하여 실질적인 혈관에서 본 실험을 진행할 계획이다.

• 대한한방성인병학회지
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• 제10권1호
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• pp.21-31
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• 2005

We have analyzed 247 patients who were admitted to the 3rd ICU for intensive care between January 2003 and December 2003 to investigate characteristics of ICU patients and obtain better guidance and management in the ICU. The results are as follows: 1) The total number of patients was 247. The proportion of males was 59.1 %, of females was 40.9%, and the ratio of male to female was about 1.45:1. 2) The most prevalent age group is those in their seventies, the proportion is 33.6%. 3) The total admission days was 3,438days, and mean patient stay being 13.9days. 4) The total number of expired patients was 26, the mortality rate was 10.5%. The mortality in distribution by disease was higest in Cerebral infarction, rate was 53.8%. the proportion of raised intracranial pressure was 42.3%, of hemorrhagic transformation was 11.5%. 5) In distribution by admission channel, Oriental hospital E.R. was 60.7%, Oriental hospital ward was 38.5%, and etc. was 0.8%. 6) The number of patients of Cerebral infarction was 146(59.1%), being the highest in distribution by chief disease and the proportion of MCA territory infarction is highest in the Cerebral infarction(61.6%). 7) In distribution by Oriental Medicine therapy, the proportion of Acupuncture treatment was 15.8%, of Acupuncture treatment combination Herb medication was 78.5%, and of Acupuncture, Herb medication plus subcutaneous Acupuncture treatment was 5.7%.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제22권2호
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• pp.133-141
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• 2000

Purpose : The purpose of this study is to estabilish clinical guidance of microvascular anastomosis in diabetic patients. This study was performed with experimental microvascular anastomosis in streptozotocin induced diabetic rats and observed histopathologic change and endohelial healing process. Materials and Methods : 70 Sprague-Dawley rats, weighting 200 to 250grams, were used for the experiment. 35 induced diabetic rats with streptozotocin and 35 control group were selected. After end-to-end carotid artery microvascular anastomosis was done, the experimental rats were sacrificed at different time interval (1st day, 3rd day, 1st week, 2nd, 4th, 6th and 8th week) for histologic examination. Light microscope observation was used in this study. Results : 1. Histopathologic changes are nearly the same healing process in two groups. But period of tissue reaction was faster in the control than diabetic group. 2. In endotheliall healing, control group started at 1 week after and completed at 4 weeks after, but diabetic group was observed partially at 4 weeks after and complete healing was not observed still at 8 weeks after. 3. In subintimal hyperplasia, control group was observed at 6 weeks after but diabetic group was observed at 6 weeks after and partially at 8 weeks after. 4. All groups showed severe inflammatory response in the early period. This respond is decreased at 2 weeks after in control group but still remained at 8 weeks after in the diabetic group. 5. In media, inflammatory response and degeneration were observed in early period. Regeneration of smooth muscle cell was observed at 1 week after in control group but 4 weeks after in the diabetic group. Conclusions : As the results of study, it could be thought that vascular regeneration process was not failured but delayed in the diabetes. It was considered that diabetes mellitus was not absolute contraindication of microvascular anastomosis.

• Child Health Nursing Research
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• 제6권2호
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• pp.240-248
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• 2000

Nurses working with families who has a hospitalized child are aware of the complexity of the tasks and stresses they deal with new setting of environment. The challenge is to assess the family coping activity that require the most immediate intervention for the effective nursing care for child and family. This study describe the family coping inventory for the clinical guidance to identify a family coping with stressors. The purpose of this study was to look at the factors related to the family's coping activity when the child was hospitalized. The data were collected with a questionnaire between July and August, 1999, in a sample of 106 families who have hospitalized child. Family coping was assessed using Family Crisis Oriented Personal Evaluation Scale(F-COPES). Data was analyzed using correlation coefficient and analysis of variance. Positive correlation was found between social support, reframe with mobilizing the family to acquire and accept help in sub-domain of family coping. Strongest correlation existed between the family's spiritual support and total family coping. The type of diagnosis, the level of family income, religion, and child's age were significantly different in family coping. The result show that the family coping is affected by the characteristics of child and family, as well as the factors of coping activity. Therefore, early assessment of family coping skill and activity is important to the prevention of problem with function toward wholeness as a unit and child's well being. It can be used with a broad range of child's hospitalization process. It also serve as a nursing record and planning tool for documenting issues that may become priorities for future interventions.

• 대한치과보철학회지
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• 제51권3호
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• pp.221-225
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• 2013

임시 보철물의 적절한 관리는 보철의 성공에 있어서 중요한 요소이다. 상악 전치 결손부 임시 보철물은 장경간의 결손부가 존재하거나, 타원형의 악궁을 가진 환자에서 자주 탈락하게 된다. 이는 상악 전치부가 구치부에 비해서 수평적인 힘에 더 많이 노출되며, 부가적으로 전방 캔틸레버 효과가 임시 보철물의 유지를 저해하고, 상악 전치부 임시 보철물은 하악의 기능 운동시 적절한 전방 유도를 제공하여야 하기 때문이다. 또한 임시 보철물의 최대 감합위에서 교합접촉은 지점선의 반대편에 위치하게 되어 그 자체로 임시 보철물의 탈락을 야기한다. 본 증례에서는 임시 임플란트를 이용하여 상악 전치부 보철물에 대한 전술한 유해 작용을 피할 수 있었고, 발치 후 치유기간 동안 환자에게 편안함과 만족감을 부여하였으므로 이를 보고하는 바이다.

• 한국응급구조학회지
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• 제6권1호
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• pp.15-26
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• 2002

As a result of analyzing problems in field practice and its effects, the following conclusions can be obtained. Man students were more satisfied with their choice of this department than woman students and woman students recognized the importance of hospital practice although they felt the need of fire fighting station practice and man students felt the necessity of hospital practice, but they answered the fire fighting station practice was important. Departments of field practice are emergency and nurse departments in hospitals and emergency aid section in fire fighting stations. And it is found that field practice was performed well in relation to major subject. Areas of practice included emergency room, operation room and extensive cure unit and the experience of ambulance was more in fire fighting station than in hospital. Clinical guidance of professor was preferred to once a week and the students answered they felt satisfaction with practice through conference. Answer that field practice was helpful in understanding class was very high as 96.8% and its connection with employment was low as 12.8%. It is found that a proper timing of field practice was winter vacation for hospital practice after completing the second semester of the first year and summer vacation for fire fighting station practice after the first semester of the second year. The most difficult department in field practice was nurse department in hospital because 'respondents were practice students' and administrative department in fire fighting stations because 'they lacked recognition of paramedic'. In making practice diary, 'describing measure results' was difficult most and the respondents wanted to keep the diary in their custody.

• 동아시아식생활학회지
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• 제15권3호
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• pp.346-356
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• 2005

This study was conducted to investigate how to apply the theories of oriental medicine appropriately, which direction should be taken, and how it should be developed The results are as follows. First, to develop medicinal cuisine, it is necessary to grasp the theoretical system, considering Ohaeng and Omi, the five viscera and the six entrails, organs and body, by raising the level of understanding comprehensively about the relationship between the characteristics of each groups of Sasang Constitutions and the theories of Eumyangohaeng, and the relationship between the theory of Kimi. and food, and then to explain developed medicinal cuisine and apply those theories to inventing new ones. Secondly, to develop medicinal cuisine for health enhancement, it is also required not only to consider constitutions but also to suggest the need of knowledge for moderation in terms of regimen along with the theory of Kimi. Thirdly, to develop medicinal cuisine according to the perspective of Kimi. Theory, what should be taken into account is not only the understanding of the characteristics of food materials, but also the properties of them that the theory of Kimi, Eumyangohaeng, and Sasang Constitutions share so that it is possible to invent medicinal cuisine which is good for anybody to protect disease specific to a certain group of constitutions with, and serves as the dietary regimen customed to each constitution group. Lastly, the scientific effect of the medicinal cuisine which is developed according to the theory of Kimi., Eumyangohaeng, and Sasang Constitutions should be verified by scientific researches and clinical experiments. And it is believed to be essential for the government to make efforts to set a standard and laws to validate the medicinal effects and the process of assessment so that the systematic development can be encouraged, and to prepare guidance to food development for national health improvement.

• 대한치과보철학회지
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• 제52권1호
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• pp.42-47
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• 2014

광범위한 치아 상실과 마모로 인한 교합면의 파괴로 수직고경이 감소된 경우 안모의 변화, 전방 유도의 상실로 인한 반대 교합을 보일 수 있으며, 또한 턱관절의 문제를 발생 시킬 수도 있다. 이러한 경우 교합 수직 고경의 증가를 통한 전악 수복을 고려할 수 있으며, 적절한 환자의 수직 고경 평가가 필요하다. 본 증례는 80세의 남자 환자로 전반적인 보철계획을 주소로 내원하였으며, 치아상실 및 마모에 따른 전치부의 반대 교합과 교합 수직 고경의 감소가 관찰되었다. 진단 모형과 방사선 사진, 임상적 검사를 이용하여 교합 관계를 분석하여 교합 수직 고경 증가를 결정하였다. 진단 wax up을 시행하였고 임시 보철물을 제작하였다. 3개월의 적응 기간 후 상악 고정성 보철물과 하악 임플란트 지지 피개의치로 최종 수복하였다. 장착 후 8개월경과 관찰 중이며 양호한 심미적 기능적 개선을 보였다.