• 대한한방내과학회지
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• 제11권1호
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• pp.15-27
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• 1990

For the purpose of examing on the efficancy of the Boolwhangumjeonggisan and on the effect of the Boolwhangumjeonggisan, dropsy animals given water boil ding abstraction exgis power. What made an experiment, the motility of isolate ileume, anticathartic action, the action of gastric juice, tied pylous ulcer and inhibited vomitting. 1. Boolwhangumjeonggisan displayed great suppresion effect in regard to automatic movement of the motility of isolated of mice and displayed anti-acethylcholine action, antibarium chloride action. Thus, the origin of muscle relaxation for internal smooth muscle is admitted. 2. It displayed great rexation effect in regard to fraction of rat's stomach and displayed contentional effect in regard to a cetylcholine and barium chloride. 3. It decreased rat of barium sulfate transport through the small intestine of mice. 4. It recognized anti-cathartic action, rat suffered from leading diarrhea by caster oil. 5. Total activity, pepsin secretion decreased and increased the pH of stomach in Shay's method. 6. It recognized powerful prevention effect on tied pylous ulcer. 7. It inhibited vomitting by administration of CuSo4 in frog.

• 한국조경학회지
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• 제45권3호
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• pp.1-8
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• 2017

이 연구는 염화칼슘이 스트로브잣나무(Pinus strobus)의 생장 및 생리반응에 미치는 영향과 그 중 염화칼슘에 민감하게 반응하는 변수를 알아보고자 실시되었다. 이를 위해 염화칼슘에 처리에 대한 스트로브잣나무의 가시적 피해, 근원경 생장, 식물체 내 수분함수량, 엽록소함량과 구성, 광계 II의 최대 활성, 전자전달율의 변화를 분석하였다. 염화칼슘 처리는 개엽하기 전에 염화칼슘 0.5, 1.0, 3.0% 수용액을 근권부에 관수하였다. 염화칼슘 처리에 의한 가시적 피해로 잎의 갈변과 탈락, 잎 마름이 나타났으며, 이러한 피해 양상은 염화칼슘 농도가 높고, 처리 기간이 길어질수록 가중되어 나타났다. 근원경(밑둥지름) 생장량 그리고 잎의 수분함수량의 감소는 염화칼슘 1.0%와 3.0% 처리에서 유의하게 나타났다. 광색소인 총엽록소함량, 광계 II의 최대 활성, 전자전달율은 염화칼슘 3.0% 처리에서 대조구 대비 유의한 감소를 보였다. 결론적으로 염화칼슘 처리는 엽 내 수분상태에 영향을 주었고, 광수확 능력과 광화학반응 능력의 감소를 초래하였다. 또한, 염화칼슘 농도와 생장 및 생리반응 변수들 간의 상호 연관성을 분석한 결과, 잎의 수분함수량과 엽록소 a와 b의 비율의 회귀식 결정계수가 상대적으로 높아, 스트로브잣나무의 염화칼슘 피해 수준에 민감하게 반응하는 변수로 나타났다.

• 한국지하수토양환경학회지:지하수토양환경
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• 제6권2호
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• pp.3-13
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• 2001

피흡착체에 대하여 곡선형 흡착등온곡선을 가지는 흡착체가 토양내 수용액상에서 이동할 때 직선형 흡착등온곡선을 가지는 흡착체와 다른 유동특성을 보인다는 사실은 널리 알려져 있다. 그러나 실험적으로 이와 같은 특성이 정밀하게 연구된 바는 그리 많지 않으며 특히 NAPLS(Non-Aqueous Phase Liquids)로서 오염된 지역의 NAPLs의 양과 미시적인 분포를 알아내기 위하여 사용되는 수리지질학적 추적자 기법에 대하여는 거의 실험된 바가 없다. 본 연구는 NAPL과 수용액간의 비계면적을 측정하기 위하여 사용되는 양이온계 계면활성제 (계면추적자), cetylpyridinium chloride (CPC)가 미세한 유리구슬로 충진된 스테인레스 컬럼내부를 통과하며 보이는 파과특성을 분석하였다. 유리구슬의 평균직경은 110$\mu\textrm{m}$였으며, 구슬의 표면은 n-decane의 얇은 막으로서 도포되어 있다. CPC는 유동하며 n-decane과 수용액의 계면에 흡착하게 되며, 실험결과 전형적인 Langmuir type의 흡착 특성을 보이는 것으로 나타났다. 앞부분과 뒷부분의 파과곡선은 각기 현저히 다른 양상을 보이며 이는 흡착등온곡선의 비직선적인 성격때문인 것으로 풀이된다. 또한 CPC의 지체상수는 CPC의 농도와 밀접한 함수관계가 있는 것으로 풀이된다. 또한 CPC의 지체상수는 CPC의 농도와 밀접한 함수관계가 있는 것으로 밝혀졌다. 컬럼에 투입되는 CPC가 pulse input일 때의 지체상수는 pulse input의 파과곡선상 나타나는 최대농도를 input농도로서 사용한 step input시의 지체상수와 일치하였다. 이 결과는 수리지질학적 특성치를 알아내기 위하여 최근 들어 활발히 개발되고 있는 추적자 기법을 적용하는데 있어서 일반적으로 통용되는 가정을 실험적으로 증명하였다는 데 그 의의가 있다.

• 한국응용약물학회:학술대회논문집
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• 한국응용약물학회 2003년도 Annual Meeting of KSAP : International Symposium on Pharmaceutical and Biomedical Sciences on Obesity
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• pp.107-107
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• 2003

The purpose of this study is to examine that the efflux transport system for choline from brain to blood is present at the blood-brain barrier (BBB) using brain efflux index (BEI) method. ［$^3$H］Choline was microinjected into parietal cortex area 2 (Par2) region of rat brain, and was eliminated from the brain with an apparent elimination half life of 45 min. The BBB efflux clearance of ［$^3$H］choline was 0.12 $m\ell$/min/g brain, which was calculated from the efflux rate constant (1.5${\times}$10$\^$-2/ min$\^$-1/) and the distribution volume in the brain slice (8.1 $m\ell$/g brain). This process was saturable and significantly inhibited by various organic cationic compounds including hemicholinium-3, tetraethylammonium chloride (TEA) and verapamil, by antioxidant, ${\alpha}$-phenyl-n-tert-butyl nitrone (PBN), and by Alzheimer's disease therapeutics, such as acetyl $\ell$-carnitine and tacrine. In conclusion, this finding is the first direct in vivo evidence that choline is transported from brain to the blood across the BBB via a carrier-mediated efflux transport process.

• 한국응용약물학회:학술대회논문집
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• 한국응용약물학회 2003년도 Annual Meeting of KSAP : International Symposium on Pharmaceutical and Biomedical Sciences on Obesity
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• pp.109-109
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• 2003

Taurine is present in a variety of tissue and exhibits many important physiological functions in many tissues. Although it is known that many tissues mediate taurine transport, its functions of taurine transport in bone have not been identified yet. In the present study, we investigated the expression of taurine transporter (TauT) and taurine uptake using mouse stromal ST2 cells and osteoblast-like MC3T3-El cells, which is bone related cells. Detection of TauT mRNA expression in these cells were performed by reverse transcription polymerase chain reaction (RT-PCR). The activity of TauT was assessed by measuring the uptake of ［$^3$H］taurine in the presence or absence of inhibitors. TauT mRNA was detected in these cells. ［$^3$H］Taurine uptake was dependent upon the presence of extracellular sodium, chloride and calcium ions, and inhibited by cold-taurine and ${\beta}$-alanine. These results suggest that taurine has biological functions in bone and some effect on the bone cells.

• Membrane and Water Treatment
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• 제8권6호
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• pp.575-590
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• 2017

PolyHIPEs membrane prepared with styrene (St), divinylbenzene (DVB), and ethylhexyl acrylate (EHA) can yield a unique pore structure provided by large voids highly interconnected by many small window throats. With the advantageous pore structure, PolyHIPE presents a potential as a support for carrier facilitated transport membrane. Tricaprylmethylammonium chloride (Aliquat 336) can be efficiently incorporated into the PolyHIPE membrane by a two-step solvent-nonsolvent method to obtain an Aliquat 336-immobilized PolyHIPE membrane with good stability. The study of Cr (VI) transport through Aliquat 336-immobilized PolyHIPE membrane indicates that the membrane has high initial flux and maxima stripping flux ($J_f^o=15.01({\mu}mol/m^2s)$, $J_s^{max}=6.15({\mu}mol/m^2s)$). The reusability study shows that the Aliquat 336-immobilized PolyHIPE membrane can maintain high Cr(VI) recovery efficiency even after 15 cycles of operations. The developed membrane was also used in the separation of Cr (VI) from other anions (i.e., $SO_4{^{2-}}$ and $NO_3{^-}$) and other cations (i.e., Ni (II), Mg (II) and Cu (II)) with good selectivity.

• Bulletin of the Korean Chemical Society
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• 제32권3호
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• pp.768-778
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• 2011

Calixpyrroles and related macrocycles are non-planer synthetic anion receptors that have attracted considerable attentions in recent years. Although the synthesis of calix[4]pyrrole (known as meso-octamethylporphyrinogen) was reported more than 100 years ago, the anion binding properties were first discovered in 1996. The simple calix[4]pyrroles can be synthesized in single step in high yield by condensation of pyrrole with acetone. The compounds showed preferential binding for halide anions including fluoride, phosphate, carboxylate, and chloride in organic media. Efforts to improve the anion affinity of calix[4]pyrrole and to enhance its selectivity have led to the synthesis of a variety of new calixpyrrole derivatives. Among the various modifications, introduction of straps on one side of the calix[4]pyrroles are the most effective. Incorporation of aromatic rings other than pyrroles also exhibited interesting binding behaviour. Introduction of signalling units as part of the strapping element enable to detect the anions on chromogenic or fluorogenic fashion. Finding of the anion transport properties across the membrane and cytotoxic effects of the calix[4]pyrroles open new window for calixpyrrole-related research. The polymer-incorporated systems have also been employed as anion complexants in solvent-solvent extraction. These old, yet easy-to-make macrocycles have well advanced more recently with the discovery of the ion-pair complexation properties. In this review, the synthetic developments and anion binding properties of calixpyrroles for the last decades will be discussed and will cover the advances in calixpyrrole chemistry.

• 공업화학
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• 제27권3호
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• pp.335-341
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• 2016

본 연구에서는 지상 및 미소중력환경하에서 물리적 승화법 공정에서의 확산-대류유동에 미치는 불순물의 영향을 이론적으로 $Hg_2Cl_2-I_2$ 시스템에 적용하여 규명하는 것이다. 이론적 해석은 증기상에서 확산-대류 흐름, 열 및 물질전달을 속도 벡터 흐름, 유선, 온도, 농도 분포를 통하여 제시된다. 결정 영역에서의 전체 몰플럭스는 중력가속도와 성분 $I_2$, 불순물에 상당히 민감하게 반응한다. 성분 $I_2$을 증가시켰을 때, 농도 대류효과는 확산-대류 유동흐름을 안정화시키는 경향이 있다. 지상중력가속도의 0.001환경에서는 유동흐름은 1차원포물선의 흐름 구조를 나타내며, 확산지배형태를 보여주고 있다. $10^{-3}$지상중력가속도 이하에서는 대류 영향은 무시할 수 있다.

• 한국화재소방학회논문지
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• 제30권6호
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• pp.23-30
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• 2016

본 연구는 화학물질 운송 화학사고를 대상으로 각 연도별 사고현황, 사고유형, 사고원인 등의 화학사고 특성을 분석하였다. 그 결과 77건의 운송 화학사고 중 74건이 유 누출 유형에 의한 사고였으며, 사고 원인으로는 41건이 교통사고에 의한 화학사고였다. 또한, 사고다발 화학물질 조사에서는 46건의 사고가 유해화학물질에 의한 사고인 것으로 조사되었다. 화학물질 운송 화학사고의 예방 및 대응을 위해서는 화학물질 유 누출과 화학물질의 운송 교통사고에 의한 화학사고에 대한 예방책의 보완이 필요하며, 운송 화학사고가 발생되었을 경우 방재가 시스템적으로 신속히 이루어질 수 있도록 범국가적이고 체계적인 화학물질 운송안전 시스템을 구축하여 화학물질 운송에 적용하는 것이 필요하다.

• 한국지하수토양환경학회:학술대회논문집
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• 한국지하수토양환경학회 2003년도 총회 및 춘계학술발표회
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• pp.188-191
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• 2003

Sing]e-well-push-pull tests were developed for use in assessing the feasibility of in-situ aerobic cometabolism of chlorinated aliphatic hydrocarbons (CAHs). The series includes Transport tests, Biostimulation tests, and Activity tests. Transport tests are conducted to evaluate the mobility of solutes used in subsequent tests. These included bromide or chloride (conservative tracers), propane (growth substrate), ethylene, propylene (CAH surrogates), dissolved oxygen (electron acceptor) and nitrate (a minor nutrient). Tests were conducted at an experimental well field of Oregon State University. At this site, extraction phase breakthrough curves for all solutes were similar, indicating apparent conservative transport of the dissolved gases and nitrate prior to biostimulation. Biostimulation tests were conducted to stimulate propane-utilizing activity of indigenous microorganisms and consisted of sequential injections of site groundwater containing dissolved propane and oxygen. Biostimulation was detected by the increase in rates of propane and oxygen utilization after each injection. Activity tests were conducted to quantify rates of substrate utilization and to confirm that CAH-transforming activity had been stimulated. In particular, the transformation of injected CAH surrogates ethylene and propylene to the cometabolic byproducts ethylene oxide and propylene oxide provided evidence that activity of the monooxygenase enzyme system, responsible for aerobic cometabolic transformations of CAHs had been stimulated. Estimated zero-order transformation rates decreased in the order propane > ethylene > propylene. The series of push-pu3l tests developed and field tested in this study should prove useful for conducting rapid, low-cost feasibility assessments for in situ aerobic cometabolism of CAHs.