• Title/Summary/Keyword: chemical susceptibility

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Source Area of the Rocks Using the West Stone Pagoda of Gameunsaji Temple Site, Korea (감은사지삼층석탑(서탑)에 사용된 석재 공급지에 대한 연구)

  • Jwa, Yong-Joo;Kim, Kun-Ki;Ko, Seok-Bae;Kim, Jong-Sun
    • The Journal of the Petrological Society of Korea
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    • v.15 no.3 s.45
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    • pp.128-138
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    • 2006
  • The west stone pagoda of Gameunssji temple site (National Treasure No. 112) has been damaged mainly by fracture, exfoliation and granular disintegration. In this study, the source area of the rocks using the west stone pagoda was examined in terms of petrological feature, magnetic susceptibility, and ${\gamma}-ray$ spectrometer. The stones include abundant crystal fragments of biotite, quartz and feldspars in the fine-grained matrix; they are petrographically discriminated to vitric-crystal tuff or crystal tuff. Measured magnetic susceptibility values are of from 10 to 20 $({\times}10^{-3}\;SI\;unit)$. From the ${\gamma}-ray$ spectrometer measurement K, eU, and eTh contents of the stones are about 3%, 0 to 8ppm, and 9 to 18 ppm, respectively. These features are used as indicators to presume the source area of the stones. Comparing the petrographical and chemical characteristics between the stones of the west stone pagoda and the country rocks near the Gameunsaji temple site, it is suggested that the most similar country rock to the stones could be dacitic volcanic rocks of the Beomgokri group in the Waeup basin. The Beomgokri group is lithostratigraphically divided into Waeupri tuff, Yongdongri tuff and Beomgokri volcanic rocks. Among the three rocks, the crystal tuff of the Beomgokri volcanic rocks seems likely to have been the source rock of the stones of the west stone pagoda.

RECK Gene Promoter rs10814325 Polymorphism in Egyptian Patients with Hepatocellular Carcinoma on Top of Chronic Hepatitis C Viral Infection

  • Fakhry, Amal Bahgat;Ahmed, Asmaa Ismail;AbdelAlim, Mahmoud Abdo;Ramadan, Dalia Ibrahim
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.5
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    • pp.2383-2388
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    • 2016
  • Background: The reversion-inducing-cysteine-rich protein with Kazal motifs (RECK) gene is a novel transformation suppressor gene linked to several malignancies. Objective: To analyze any association between RECK gene rs10814325 single-nucleotide polymorphism (SNP) and HCC susceptibility with various clinicopathological and laboratory data. Materials and Methods: RECK gene rs10814325 SNP was estimated, using real-time PCR, in 30 HCC patients on top of HCV infection, 30 HCV related cirrhotic patients and 30 healthy controls. Results: No special pattern of association could be detected on comparing the RECK gene rs10814325 genotypes(P=0.5), or alleles(P=0.49) among the studied groups. HCC patients with TT genotype had younger age (mean of $54.1{\pm}6.0$ years vs $60.6{\pm}10.2$ years for TC/CC genotypes, P=0.035). Abdominal distension was significantly greater in TT genotype patients (75% vs 30%for TC/CC genotypes, P=0.045). The TT genotype was present in 75% of patients with lymph node metastasis. Serum GGT levels were higher in TT genotype patients [80 (48.5-134.8) IU/L vs 40 (33-87.5) IU/L for TC/CCgenotypes], and lower limb edema was observed in 60% for TT vs 20% for TC/CCgenotypes, but both just failed to reach significance (p=0.05 and p=0.06 respectively). Conclusions: RECK gene rs10814325 T>C could not be considered a risk factor for HCC development on top of HCV, but may be related to the disease progression and metastasis.

Interferon-γ and Interleukin-10 Gene Polymorphisms are not Predictors of Chronic Hepatitis C (Genotype-4) Disease Progression

  • Bahgat, Nermine Ahmed;Kamal, Manal Mohamed;Abdelaziz, Ashraf Omar;Mohye, Mohamed Ahmed;Shousha, Hend Ibrahim;ahmed, Mae Mohamed;Elbaz, Tamer Mahmoud;Nabil, Mohamed Mahmoud
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.12
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    • pp.5025-5030
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    • 2015
  • Immunoregulatory cytokines have an influence on hepatitis C virus (HCV) infection outcome. This study aimed to determine whether single nucleotide polymorphisms (SNP) in IFN- ${\gamma}$ and IL-10 genes are associated with susceptibility and/or are markers of prognosis regarding chronic hepatitis C outcomes. IFN ${\gamma}$ (+874T/A) and IL-10 (-1082G/A) genotypes were determined in 75 HCV genotype 4 patients with different disease severities (chronic hepatitis, n=25, liver cirrhosis and hepatocellular carcinoma (HCC) on top of liver cirrhosis, n=50) and 25 healthy participants using allele-specific polymerase chain reaction. No statistical differences in allele or genotype distributions of IFN ${\gamma}$ and IL-10 genes were detected between patients and controls or between patientgroups. No significant difference in the frequency of IL-10 SNP at position -1082 or IFN-${\gamma}$ at position +874T/A was found between chronic HCV genotype 4 and with progression of disease severity in liver cirrhosis or HCC. In conclusion; interferon-${\gamma}$ and interleukin-10 gene polymorphisms are not predictors of disease progression in patients with chronic hepatitis C (Genotype-4).

Changes of Carbohydrate Composition and Enzyme Adsorption on the Hydrolysis of Steam Exploded Wood by Cellulase (Cellulase에 의한 폭쇄재의 가수분해에 있어서 탄수화물조성 및 효소흡착량 변화)

  • Yang, Jae-Kyung;Kim, Chul-Hwan
    • Journal of the Korean Wood Science and Technology
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    • v.29 no.4
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    • pp.67-78
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    • 2001
  • Two species(Quercus mongolica, populus euramericana) of hardwood chips were subjected to steam explosion 25 kg/$cm^2$, for 6 min. The exploded woods were treated by the single or multi-stage chemical process with sodium hydroxide, sodium hypochlorite and sodium chlorite. The multi-stage treatment of exploded wood can be successfully removed lignin. Enzymatic hydrolysis rate of substrate varied from 25% for exploded wood to about 80% for the multi-chemical treated exploded wood. The enzymatic susceptibility was different among wood species. The multi chemical treatment of the exploded wood resulted in the high rate of glucose in the enzymatic hydrolyzate. Cellulase adsorption increased at high lignin content of substrates, while crystallinity, pore area and specific surface area of substrates did not affected enzyme adsorption. According to the proposed pretreatment and saccharification process in this study, it can be acquired about 37~40 kg of glucose from 100 kg of hardwood.

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Review on Safety and Health Information on Humidifier Disinfectant (가습기 살균제 제품에 표기된 안전보건정보 고찰)

  • Park, Dong-Uk;Lee, Seunghee;Lim, Heung-Kyu;Bae, Seo-Youn;Ryu, Seung-Hun;Ahn, Jong-Ju
    • Journal of Environmental Health Sciences
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    • v.43 no.5
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    • pp.349-359
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    • 2017
  • The objective of this study is to review the safety and health information displayed on containers of humidifier disinfectants (HD). We summarized not only general characteristics related to the marketing and manufacturing of HD, such as the duration sold and the name of the company, but also the safety and health information, such as identification of disinfectants, recommended use volume, and precautions. All of this information was reviewed by HD brand. We collected safety and health information from 31 HD brands. We found that companies that sold and manufactured HD brands differ. Two companies were found to sell their HD without permission after 2011 when the health effects caused by HD were widely known. The name of the disinfectants were not identified on the container of HD. The recommended volumes were found not to be based on toxicological evidence and set without consideration of the level of susceptibility of users. Most companies displayed phrases such "this HD is safe for humans, even children" on the front of the container. No inhalation and skin toxicity precautions were provided. In conclusion, most HD did not properly display information related to safety and health to protect the health of HD users. There has been no official investigation to evaluate the risks posed by HD, such as the sales volume by HD, identification of chemical disinfectants, or their concentration, nor have there been actions to control the chemical quality of HD. In addition, government actions to punish the malicious practices of companies that manufactured and sold HD were found to inappropriate.

Variations of Clay Mineral Assemblage, Colour, and Microfossil Abundance in the Tertiary Sediments from the Pohang Area During Chemical Weathering (포항지역(浦項地域) 제(第)3기층(紀層) 퇴적암(堆積岩)중 화학적풍화작용(化學的風化作用)이 결토광물조성(結土鑛物組成), 화학조성(化學組成), 암색(岩色) 및 미화석(微化石) 산출빈도(産出頻度)에 미치는 영향)

  • Moon, Hi-Soo;Yun, Hyesu;Min, Kyung Duck;Lee, Hyun Koo;Lee, Jong Chun
    • Economic and Environmental Geology
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    • v.23 no.2
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    • pp.201-213
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    • 1990
  • Mineralogy, chemistry, physical property, and fossil abundance have been studied for the samples collected from three weathering profiles, two from the Duho Formation and one from the Hagjeon Formation in the Tertiary sediments in the Pohang area. The mineralogy of the samples from the Duho Formation shows somewhat different from that of the Hagjeon Formation. Kaolinite is more abundant and shows higher crystallinity in samples from the Duho Formation than those in the Hagjeon Formation, but clay mineral assemblage in each weathering profile remain fairly constant with depth. This difference in mineral distribution seems to be inherited from original source materials. It indicates that little or not severe leaching has been taking place in these three weathering profiles. Weathering indicies indicate different degrees of susceptibility to chemical weathering in these two formations. The Duho Formation has a higher degree of susceptibility to weathering than that of the Hagjeon Formation which is mainly due to differences in clay mineral assemblages in both formations. A noticeble colour difference between oxidized and unoxidized zones in each profile can be easily recognized which is definetely due to different decomposition rate organic carbon by various oxidation state from surface to bottom of the profile. Weathering process have also intensively influenced microfossil preservation about up to 7-10 m in depth in the Duho Formation. Consequently, characteristics observed at weathering surface should be used as a subsidiary tool in setting geologic boundary or establishing formation. Great care must be taken to choose sampling site for microfossil study.

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Development of Additive to Modify the SDAR (Solvent DeAsphalting Residue) and Laboratory Performance Evaluation of Asphalt Mixture with Modified SDAR (고품위화 정제공정 부산물(SDAR) 활용을 위한 첨가제 개발 및 이를 이용한 아스팔트 혼합물의 실내 공용성능 평가)

  • Baek, Cheolmin;Yang, Sung Lin;Hwang, Sung Do
    • International Journal of Highway Engineering
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    • v.18 no.6
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    • pp.97-104
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    • 2016
  • OBJECTIVES : The objective of this research is to develop additives for the modification of Solvent DeAsphalting Residue (SDAR) to be used as pavement materials, and evaluate the performance of asphalt mixture manufactured using the SDAR modified by developed additives. METHODS : The SDAR generally consists of more asphaltenes and less oil components compared to the conventional asphalt binder, and hence, the chemical/physical properties of SDAR are different from that of conventional asphalt binder. In this research, the additives are developed using the low molecular oil-based plasticizer to improve the properties of SDAR. First, the chemical property of two SDARs is analyzed using SARA (saturate, aromatic, resin, and asphaltene) method. The physical/rheological properties of SDARs and SDARs containing additives are also evaluated based on PG-grade method and dynamic shear-modulus master curve. Second, various laboratory tests are conducted for the asphalt mixture manufactured using the SDAR modified with additives. The laboratory tests conducted in this study include the mix design, compactibility analysis, indirect tensile test for moisture susceptibility, dynamic modulus test for rheological property, wheel-tracking test for rutting performance, and direct tension fatigue test for cracking performance. RESULTS : The PG-grade of SDARs is higher than PG 76 in high temperature grades and immeasurable in low temperature grades. The dynamic shear modulus of SDARs is much higher than that of conventional asphalt, but the modified SDARs with additives show similar modulus compared to that of conventional asphalt. The moisture susceptibility of asphalt mixture with modified SDARs is good if, the anti-stripping agent is included. The performance (dynamic modulus, rutting resistance, and fatigue resistance) of asphalt mixture with modified SDARs is comparable to that of conventional asphalt mixture when appropriate amount of additives is added. CONCLUSIONS : The saturate component of SDARs is much less than that of conventional asphalt, and hence, it is too hard and brittle to be used as pavement materials. However, the modified SDARs with developed additives show comparable or better rheological/physical properties compared to that of conventional asphalt depending on the type of SDAR and the amount of additives used.

Varietal reactions of Strawberry to two isolates of Mycosphaerella fragariae and its chemical control (딸기 반엽병균의 계통에 대한 품종간 저항성과 살균제의 방제효과)

  • Kim C. G.;Cho C. T.;Bai T. U.;Han H. S.;Ha S. Y.;Moon B. J.
    • Korean journal of applied entomology
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    • v.17 no.3 s.36
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    • pp.149-154
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    • 1978
  • Varietal resistance of 49 strawberry varieties to two isolates of Mycosphaerella fragariae was investigated by incoulation experiments and its chemical control was also studied. 1. The susceptibility of varieties and pathogenecity of the isolates were significantly different. 2. in most instances isolate $S_3$ and the reactions of varieties to the isolates were different. 3. Among the varieties tested, Tioga, Donner, Marhall, Northwest, Red star, Senga, sengana, Shasta, Torrey, Hokowase and Daehak No. 1 were found highly susceptible to isolate $K_2$, and America, Dabreak, Takanae, Kurumae No. 103, Horida's wander, Benizuru, Hukuba and Himiko were found as highly resistant. 4. It was apparent that America, Morioka No. 17, Takanae, Kurumae No. 13, Horida's wander, Benizuru and Hukuba were resistant to isolate $S_3$ and Marshall, Tioga were very susceptible to it. 5. As for the susceptibility of varieties by old End new leaf to isolate $K_2$, old leaves were evaluated as highly resistant. 6. Under the conditions of artificial infection Captan was the most effective in controlling for the leafspot and followed by Zineb and Difolatan.

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Analysis of Interleukin-6 Gene Polymorphisms in Behcet’s Disease Using RFLP and DHPLC (RFLP와 DHPLC를 이용한 베체트병 환자에서 Interleukin-6 유전자 다형성의 분석)

  • Jang, Won-Cheol;Park, Sang-Beom;Nam, Yun-Hyeong;Lee, Jae-Sik
    • Journal of the Korean Chemical Society
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    • v.50 no.2
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    • pp.123-128
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    • 2006
  • Behcet's disease (BD) is a systemic vasculitis characterized by recurrent oral and genital ulcers, and ocular inflammation, and which may involve the joints, skin, central nervous system and gastrointestinal tract. Although the exact pathogenesis for BD is not completely understood, it has been suggested that the disease is triggered in genetically susceptible individuals by environmental factors, such as microbial agents. It is noted that multiple genes, including MHC (major histocompatibility complex) and non-MHC genes, are implicated in the pathogenesis of BD. This study tries to determine whether IL-6 gene polymorphisms are associated with susceptibility to Behcet's disease in Koreans. Gene polymorphisms were typed by VNTR (variable number of tandem repeat), RFLP (restriction fragment length polymorphism), DHPLC (denaturing high performance liquid chromatography).There were no evidences for genetic association conferred by the IL-6prom polymorphism. However, significant differences in the IL-6vntr genotype and allele frequencies were found between patients with BD and controls. The IL-6vntr*C allele appeared to be an additional susceptibility gene to Korean BD. Further studies in other populations and gene are required to confirm these results.

A Study on the Rate of Occurrence according to Watering Methods, Susceptibility and Chemical Control of Chrysanthemum Nematode (국화잎 선충에 대한 저항성 검정, 관수방법에 따른 국화잎선충의 피해율 및 화학적 방제에 관한 연구)

  • Kim, Young Jin;Choi, Young Eoun
    • Current Research on Agriculture and Life Sciences
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    • v.5
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    • pp.106-111
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    • 1987
  • The susceptibility of 8 chrysanthemum varieties to Apelenchoides ritzemabosi, Shuhonothikara and Sagakiku were resistant by 11.7% and 14.5% each infested leaf, Sinrokusiogio, Dangonanako and Sintoa were susceptible as above 50%, Gold wave and Tenju were modertae by 24 to 26%. Percentage of infested leaf was positively correlated with the number of epidermal hair but not with leaf area, leaf thickness, stomatal size, number of stomata and length of epidermal hair. In effect of watering method, Polyethylene film cover plot was lowest by 9.4%, next conventional watering plot by 50%, Conventional watering and spray plot was the highest by 62%. The infested leaf rate was closely related with a number of rainy days than the amount of rainfall. Effect of chemical soil treatment, Temik showed the lowest infested leaf rate by 5%. There was no significant difference between the chemicals except Temik, but these are markedly effective in compare to control.

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