• 한국정밀공학회지
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• 제23권9호
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• pp.164-173
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• 2006

The cooling capacity of a micro-heat pipe is mainly governed by the magnitude of capillary pressure induced in the wick structure. For microchannel wicks, a higher capillary pressure is achievable for narrower and deeper channels. In this study, a metallic micro-heat pipe adopting high-aspect-ratio microchannel wicks is fabricated. Micromachining of high-aspect-ratio microchannels is done using the laser-induced wet etching technique in which a focused laser beam irradiates the workpiece placed in a liquid etchant along a desired channel pattern. Because of the direct writing characteristic of the laser-induced wet etching method, no mask is necessary and the fabrication procedure is relatively simple. Deep microchannels of an aspect ratio close to 10 can be readily fabricated with little heat damage of the workpiece. The laser-induced wet etching process for the fabrication of high-aspect-ratio microchannels in 0.5mm thick stainless steel foil is presented in detail. The shape and size variations of microchannels with respect to the process variables, such as laser power, scanning speed, number of scans, and etchant concentration are closely examined. Also, the fabrication of a flat micro-heat pipe based on the high-aspect-ratio microchannels is demonstrated.

• 한국통신학회논문지
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• 제27권11C호
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• pp.1097-1105
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• 2002

아날로그 모니터를 사용하는 디스플레이 시스템의 경우, 프레임 버퍼의 영상 정보 갱신 주기와 모니터 주사 주기가 맞지 않는 경우, 장면 변화가 심한 동영상 디스플레이시에 화면이 상단과 하단으로 다른 영상이 나타나는 tearing 현상이 발생한다. 다중 카메라 채널을 디스플레이하여야 하는 영상 감시 시스템인 DVR(Digital Video Recorder) 시스템에서는 프레임 버퍼 갱신율이 매우 높기 때문에 tearing 현상이 심하게 된다. 본 논문에서는 윈도우즈 기반 DVR에서 디스플레이 속도 성능의 저하가 별로 없으면서, tearing 현상을 방지한 개선된 디tm플레이 시스템 구조를 제안한다. 제안된 디스플레이 시스템의 효율성은 실험을 통하여 입증하였다.

• 한국전기전자재료학회논문지
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• 제19권11호
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• pp.1005-1009
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• 2006

High quality three-dimensional (3D) heterostructures were constructed by selective area (SA) molecular beam epitaxy (MBE) using a specially patterned GaAs (001) substrate to improve the efficiency of tarrier transport. MBE growth parameters such as substrate temperature, V/III ratio, growth ratio, group V sources (As2, As4) were varied to calibrate the selective area growth conditions and the 3D GaAs-AlGaAs heterostructures were fabricated into the ridge type and the V-groove type. Scanning micro-photoluminescence $({\mu}-PL)$ measurements and the following analysis revealed that the gradually (adiabatically) coupled 1D-2DEG (electron gas) field effect transistor (FET) system was successfully realized. These 3D-heterostructures are expected to be useful for the realization of high-performance mesoscopic electronic devices and circuits since it makes it possible to form direct ohmic contact onto the (quasi) 1D electron channel.

• Journal of Magnetics
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• 제18권4호
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• pp.422-427
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• 2013

The aim of this study was to investigate effects of the number of acquisitions (NEX) on signal-to-noise (SNR) and artifacts in SENSE parallel imaging of magnetic resonance imaging (MRI). 3.0T MR System, 8 Channel sensitivity encoding (SENSE) head coils were used along with an in-vivo phantom. Reference sequence of 3D fast field echo (FFE) was consisted of NEX values of 2, 4, 6, 8, 10 and 12. The T2 turbo spin echo (TSE) sequence used for exams achieved SENSE factors of 1.2, 1.5, 1.8, 2.0, 2.2, 2.5, 2.8, 3.0, 3.2, 3.5, 3.8 and 4.0. Exams were conducted five times for each SENSE factor to measure signal intensity of the object, the posterior phase-encode direction and frequency direction. And SNR was calculated using mean values. SENSE artifacts were identified as background signal intensity in the phase-encoded direction using MRIcro. It was found that SNR increased but SENSE artifacts reduced with NEX of 4, 8 and 12 when the NEX increased in reference scan. It is therefore concluded that image quality can be improved with NEX of 4, 8 and 12 for reference scanning.

• 대한전자공학회논문지
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• 제21권5호
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• pp.33-40
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• 1984

보통의 초음파 도플러 시스템은 게이트된 연속파(gutted CW)를 사용하기 때문에 초음파 B스캔너와 같이 스캔할 수 있는 초음파 도플러 진단기는 많은 선형 고주파 증폭기를 필요로 한다. 제작이 어려운 고압 고주파 증폭기를 사용하지 않고 초음파 소자를 직접 임펄스로써 구동하는 펄스 도플러 시스템이 이론적으로 해석되었으며, 실험적으로 연구되었다. 설계된 시스템은 8채널 기능을 갖고, 직각 검파(quodrature detection)를 사용하여 목표물의 운동방향을 알 수 있도록 하였으며, 감쇄영향을 보상할 구 있도록 하였다. 연구된 시스템은 주파수 축상에서 실시간으로 혈류진단을 할 수 있는 다중 채널 진단기의 가능성을 보이고 있다.

• JSTS:Journal of Semiconductor Technology and Science
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• 제11권4호
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• pp.238-246
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• 2011

A 3-5 GHz UWB radar chip in 0.13 ${\mu}m$ CMOS process is presented in this paper. The UWB radar transceiver for surveillance and biometric applications adopts the equivalent time sampling architecture and 4-channel time interleaved samplers to relax the impractical sampling frequency and enhance the overall scanning time. The RF front end (RFFE) includes the wideband LNA and 4-way RF power splitter, and the analog signal processing part consists of the high speed track & hold (T&H) / sample & hold (S&H) and integrator. The interleaved timing clocks are generated using a delay locked loop. The UWB transmitter employs the digitally synthesized topology. The measured NF of RFFE is 9.5 dB in 3-5 GHz. And DLL timing resolution is 50 ps. The measured spectrum of UWB transmitter shows the center frequency within 3-5 GHz satisfying the FCC spectrum mask. The power consumption of receiver and transmitter are 106.5 mW and 57 mW at 1.5 V supply, respectively.

• Biomolecules & Therapeutics
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• 제22권6호
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• pp.519-524
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• 2014

We have previously shown that 2,4,3',5'-tetramethoxystilbene (TMS), a trans-stilbene analogue, induces apoptosis in human cancer cells. However, the detailed mechanisms of mitochondria-dependent apoptosis induced by TMS are not fully understood. In the present study, the possible roles of annexin A5 in TMS-mediated apoptosis were investigated in MCF7 human breast cancer cells. Quantitative real-time PCR analysis and Western blot analysis showed that the expression of annexin A5 was strongly increased in TMS-treated cells. TMS caused a strong translocation of annexin A5 from cytosol into mitochondria. Confocal laser scanning microscopic analysis clearly showed that TMS induced translocation of annexin A5 into mitochondria. TMS increased the expression and oligomerization of voltage-dependent anion channel (VDAC) 1, which may promote mitochondria-dependent apoptosis through disruption of mitochondrial membrane potential. When cells were treated with TMS, the levels of Bax, and Bak as well as annexin A5 were strongly enhanced. Moreover, we found that the cytosolic release of apoptogenic factors such as cytochrome c, or apoptosis-inducing factor (AIF) in mitochondria was markedly increased. Annexin A5 depletion by siRNA led to decreased proapoptotic factors such as Bax, Bak, and annexin A5. Taken together, our results indicate that annexin A5 may play an important role in TMS-mediated mitochondrial apoptosis through the regulation of proapoptotic proteins and VDAC1 expression.

• Korean Journal of Chemical Engineering
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• 제35권12호
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• pp.2487-2495
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• 2018

Inspired by the specific amino acid sequence Asn-Pro-Ala (NPA) of water channel aquaporins (AQPs), we fabricated polyamide (PA) nanofiltration (NF) membranes by introducing reduced glutathione (GSH) in interfacial polymerization (IP) method. Fourier transform infrared spectroscopy (ATR-FTIR), X-ray photoelectron spectrometry (XPS), scanning electron microscope (SEM), atomic force microscopy (AFM), zeta potential and static water contact angle measurement were employed to characterize the chemical composition, morphology, electronegativity and hydrophilicity of the NF membranes. The water flux of GSH/PIP-TMC NF membrane reached $32.00L\;m^{-2}h^{-1}$ at 0.2 MPa, which was approximately twice than that of pristine PIP-TMC NF membrane when the ratio of GHS to piperazidine (PIP) was 40% during IP process. More water channels were built as GSH was embedded into PA layer. The fabricated NF membranes also took on potent rejection for dyes and $Na_2SO_4$. This study presents a simple and facile method to simulate water channels-based biological materials which may find potential application in water treatment.

• Current Optics and Photonics
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• 제5권4호
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• pp.421-430
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• 2021

The multifocal multiphoton microscopy (MMM) enables high-speed imaging by the concurrent scanning and detection of multiple foci generated by lenslet array or diffractive optical element. The MMM system mainly suffers from crosstalk generated by scattered emission photons that form ghost images among adjacent channels. The ghost image which is a duplicate of the image acquired in sub-images significantly degrades overall image quality. To eliminate the ghost image, the photon reassignment method was established using maximum likelihood estimation. However, this post-processing method generally takes a longer time than image acquisition. In this regard, we propose a novel strategy for rapid noise reduction in the MMM system based upon Monte-Carlo (MC) simulation. Ballistic signal, scattering signal, and scattering noise of each channel are quantified in terms of photon distribution launched in tissue model based on MC simulation. From the analysis of photon distribution, we successfully eliminated the ghost images in the MMM sub-images. If the priori MC simulation under a certain optical condition is established at once, our simple, but robust post-processing technique will continuously provide the noise-reduced images, while significantly reducing the computational cost.

• 센서학회지
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• 제28권2호
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• pp.76-80
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• 2019

The characteristics of a titanium oxide layer prepared using a plasma electrolytic oxidation (PEO) process were investigated, using an extended gate ion sensitive field effect transistor (EG-ISFET) to confirm the layer's capability to react with hydrogen ions. The surface morphology and element distribution of the PEO-processed titanium oxide were observed and analyzed using field-emission scanning-electron microscopy (FE-SEM) and energy-distribution spectroscopy (EDS). The titanium oxide prepared by the PEO process was utilized as a hydrogen-ion sensing membrane and an extended gate insulator. A commercially available n-channel enhancement MOS-FET (metal-oxide-semiconductor FET) played a role as a transducer. The responses of the PEO-processed titanium oxide to different pH solutions were analyzed. The output drain current was linearly related to the pH solutions in the range of pH 4 to pH 12. It was confirmed that the titanium-oxide layer prepared by the PEO process could feasibly be used as a hydrogen-ion-sensing membrane for EGFET measurements.