• Journal of The Korean Astronomical Society
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• v.29 no.spc1
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• pp.119-122
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• 1996

The case for a massive black hole in the center of the Galaxy is reassessed using improved modeling techniques and observational data. A dark mass of ${\~}{\times} 10^6$ Mo is present within 0.2 pc of the Galactic center. However, the available data can be modeled, without appealing to a massive black hole, using an extended distribution of dark stellar remnants (neutron stars and stellar mass black holes) provided that the stellar initial mass function in the central parsec is deficient in stars less massive than $\~$1 Mo. Such a situation may be a natural consequence of repeated gas build-up followed by starbursts in the central region. A clear distinction between this and the massive central black hole model cannot be made using red giant tracers outside 0.2 pc due to uncertainties in the radial velocity dispersion distribution. The cluster of massive early-type emission-line stars in the central parcsec more effectively probe the mass distribution close to Sgr A $\ast$, but their small number and partial rotational support complicate mass determinations. Proper motion determinations for stars within 0.5' of Sgr A$\ast$ may be the most effective means of unambiguously determining the mass distribution in the immediate vicinity of the Galactic center.

• Proceedings of the KIEE Conference
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• 2008.07a
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• pp.420-421
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• 2008

배전설비의 안정성검토 및 조형물과 충분한 측방이격거리 확보검토를 위해 일반지역 직선선로에서 2400mm 완철을 설치한 보통장주와 편출장주 일반용 콘크리트 전주의 강도를 검토하였으며, 편출장주시 완철의 길이변화가 전주강도에 미치는 영향을 살펴보았다. 표준경간[3]에서 보통장주형태의 전주는 대용량선로의 전선(ACSR/AW-OC $240mm^2$)을 설치한 경우에도 허용강도이내였으며, 표준경간에서 편출장주 형태의 전주는 보통장주일때 보다 전주의 휨모멘트는 증가하였고 일반선로 ACSR/AW-OC$160mm^2$ 이하의 전선을 설치한 경우 허용강도를 갖게 됨을 알 수 있었다. 또한, 편출장주 완철의 길이를 2400mm에서 3200mm로 증가시킨 경우, 전주의 휨모멘트는 증가하였으며, 전주는 표준경간이 40M 이하에서 대용량선로의 전선을 설치한 경우에도 허용강도를 갖게 됨을 알 수 있었다.

• Archives of Pharmacal Research
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• v.22 no.2
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• pp.189-193
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• 1999

Reversed-phase high-performance liquid chromatography/mass spectrometry (HPLC/MS) with an eletcrospray ionization (ESI) interface was applied to the identification of metabolites of IY81149 in the rat plasma. Fragments obtained using collision-induced dissociation (CID) in both positive and negative modes were utilized to elucidate the structure of metabolites. The eluent from the conventional HPLC column was split and directly introduced into an ESI-mass spectrometer for the identification of the structures. the CID technique allowed the sensitive identification of sulfonyl-IY81149 and hydroxy-IY81149 from the rat plasma.

• Journal of Marine Bioscience and Biotechnology
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• v.16 no.1
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• pp.26-35
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• 2024

Chlorella has various biotechnological applications, including in the biomedical and pharmaceutical industries, because of its advantages, including rich nutrients, fast growth rate, easy cultivation, and high biomass. We used the Agrobacterium-mediated transformation method to express human GM-CSF and EGF proteins, which are widely used in regenerative medicine, cosmetics, and pharmaceutical materials in Chlorella. The codon-optimized hGM-CSF and hEGF genes were cloned into plant binary vectors and transformed into Chlorella vulgaris using the Agrobacterium-mediated coculture transformation method. After transformation, genomic DNA PCR was performed for each C. vulgaris line that was stably subcultured on an antibiotic-resistant solid medium to confirm the insertion of hGM-CSF and hEGF into the chromosome. Furthermore, PT-PCR and protein expression of hGM-CSF and hEGF in each transformed C. vulgaris were significantly increased compared to the untransformed Chlorella. This study suggests that high-value proteins, including hGM-CSF and hEGF, which are foreign genes of C. vulgaris, can be stably expressed through the Agrobacterium-mediated Chlorella transformation system.

• Journal of Radiation Industry
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• v.18 no.1
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• pp.1-7
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• 2024

The International Commission on Radiological Protection (ICRP) lowered the annual equivalent dose limit of lens of the eye for radiation workers from 150 to 20 mSv in April 2011. This trend of lowering the equivalent dose limit for radiation workers has been observed worldwide, including international organizations such as the International Atomic Energy Agency (IAEA), International Organization for Standardization (ISO) and the European Commission (EC). In 2016, the Nuclear Safety and Security Commission of South Korea published research results that included a proposal for lowering the equivalent dose limit of lens of the eye for radiation workers in line with the ICRP recommendation. However, as of now, South Korea's Nuclear Safety Act and related regulations still specify an annual equivalent dose limit of lens of the eye as 150 mSv for radiation workers. The IAEA and ISO have issued guidelines regarding radiation protection for lens of the eye and recommended a dose level for the lens of the eye at 5 or 6 mSv per year for periodic monitoring of the equivalent dose for the lens of the eye.

• International Journal of Highway Engineering
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• v.14 no.2
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• pp.145-155
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• 2012

At present, Seoul City is putting the bus exclusive lane system into practice according to mass transit revitalization policy. Starting with the installation of roadside bus exclusive lane in the past, at present, even the road sections for central- lane bus exclusive lane system are on the increase. The purpose of this research is to analyze the factors giving impacts on bus accident on central bus exclusive lane and roadside bus exclusive lane. In case of the central bus exclusive lane, the 6 variables, such as the number of bus routes, number of access & entrance to central lanes patterns, whether the stop line of central lanes retreats or not, separated distance between the stop line of central lanes and crosswalks, traffic volume, and number of bus routes stopping at bus stops on reversible lanes, were found to have a significant influence on bus accidents. In case of roadside bus exclusive lane sections, the four variables such as the number of right-turn bus routes, whether to be chronic illegal parking & stopping, time for the walk signal, and forms of land use, etc. were found to have a significant influence on bus accident.

• Transactions on Electrical and Electronic Materials
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• v.17 no.3
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• pp.129-133
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• 2016

Theoretical and graphical analysis of pull-in-voltage and figure of merit for a fixed-fixed capacitive Micro Electromechanical Systems (MEMS) switch is presented in this paper. MEMS switch consists of a thin electrode called bridge suspended over a central line and both ends of the bridge are fixed at the ground planes of a coplanar waveguide (CPW) structure. A thin layer of dielectric material is deposited between the bridge and centre conductor to avoid stiction and provide low impedance path between the electrodes. When an actuation voltage is applied between the electrodes, the metal bridge acquires pull in effect as it crosses one third of distance between them. In this study, we describe behavior of pull-in voltage and figure of merit (or capacitance ratio) of capacitive MEMS switch for five different dielectric materials. The effects of dielectric thicknesses are also considered to calculate the values of pull-in-voltage and capacitance ratio. This work shows that a reduced pull-in-voltage with increase in capacitance ratio can be achieved by using dielectric material of high dielectric constant above the central line of CPW.

• Development and Reproduction
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• v.15 no.3
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• pp.239-247
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• 2011

Spermatogenesis and taxonomic values of mature sperm morphology of in male Septifer (Mytilisepta) virgatus were investigated by transmission electron microscope observations. The morphologies of the sperm nucleus and the acrosome of this species are the cylinder shape and cone shape, respectively. Spermatozoa are approximately 45-50 ${\mu}m$ in length including a sperm nucleus (about 1.26 ${\mu}m$ long), an acrosome (about 0.99 ${\mu}m$ long), and tail flagellum (about 45-47 ${\mu}m$). Several electron-dense proacrosomal vesicles become later the definitive acrosomal vesicle by the fusion of several Golgi-derived vesicles. The acrosome of this species has two regions of differing electron density: there is a thin, outer electron-dense opaque region (part) at the anterior end, behind which is a thicker, more electron-lucent region (part). In genus Septifer in Mytilidae, an axial rod does not find and also a mid-central line hole does not appear in the sperm nucleus. However, in genus Mytilus in Mytilidae, in subclass Pteriomorphia, an axial rod and a mid-central line hole appeared in the sperm nucleus. These morphological differences of the acrosome and sperm nucleus between the genuses Septifer and Mytilus can be used for phylogenetic and taxonomic analyses as a taxonomic key or a significant tool. The number of mitochondria in the midpiece of the sperm of this species are five, as seen in subclass Pteriomorphia.

• Journal of the Korean Professional Engineers Association
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• v.21 no.4
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• pp.19-32
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• 1988

Whereas is non-symmetrical distribution manufacturing process the traditional X-chart by Shewhart is not plotted relatively on the central line but plotted on the skew of upper-hand side or lower-hand side. That is to say, for the purpose of producing either upper-specification-oriented items or lower-specification-oriented items, and when we carry out tighter control so as to have them pass only its specifications, the distribution shape naturally has a non-normal distribution. In the Shewhart X-chart, which is the most widely used one in Korea, such skewed distributions make tile plots to be inclined below or above the central line or outside the control limits although no assignable causes can be found. To overcome such short comings is non-normally distributed processes, a distribution-free type of confidence interval can be used, which should be haled on order statistics. This thesis is concerned with the design of control chart based on a sample median which is easy to use in practical situation and therefore properties for non-normal distributions, such as Gamma, Beta, Lognormal, Weibull, Pareto, and Truncated-normal distributions, may be easily analyzed. To enhance this improvement, I proved the property of practical applications of control chart method by comparing and analyzing the case studies of practical application of special purpose control chart method, and also by introducing the new designed median control chart.

• Archives of Pharmacal Research
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• v.28 no.6
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• pp.691-698
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• 2005

Phlorotannins, the polyphonic compounds found in brown Eisenia and Ecklonia algae, have several pharmacologically beneficial effects such as anti-inflammation. In addition, our recent data show that these compounds may improve the cognitive functions of aged humans suggesting the potential ability to enhance memory in several neurodegenerative disorders. To examine the experimental hypothesis that two effective components of Ecklonia cava, dieckol and phlorofucofuroeckol (PFF), have memory-enhancing abilities, both were administered orally to mice before a passive avoidance test. The repeated administration of either dieckol or PFF dose-dependently reduced the inhibition of latency by the administration of ethanol. To investigate the mode of memory-enhancing actions, the levels of major central neurotransmitters in three different regions (striatum, hippocampus, and frontal cortex) of the mouse brain were measured. The levels of some of the neurotransmitters were significantly changed by ethanol. Both dieckol and PFF altered the levels of some neurotransmitters modified by the ethanol treatment. It is noteworthy that both dieckol and PFF increased the level of acetylcho-line, and they exerted anticholinesterase activities. Overall, the memory-enhancing abilities of dieckol and PFF may result from, at least in part, the increment of the brain level of acetylcho-line by inhibiting acetylcholinesterase.