• 한국전기전자재료학회논문지
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• 제19권11호
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• pp.994-999
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• 2006

For low-cost embedded EEPROM, in this paper, single polysilicon EEPROM and n-channel high-voltage LDMOST device are developed in a $0.25{\mu}m$ standard CMOS logic process. Using these devices developed, the EEPROM chip is fabricated. The fabricated EEPROM chip is composed of 1 Kbit single polysilicon EEPROM away and high voltage driver circuits. The program and erase characteristics of the fabricated EEPROM chip are evaluated using 'STA-EL421C'. The fabricated n-channel high-voltage LDMOST device operation voltage is over 10 V and threshold voltage window between program and erase states of the memory cell is about 2.0 V.

• 대한기계학회논문집A
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• 제35권2호
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• pp.131-134
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• 2011

본 논문에서는 한시적 세포포집 구조물을 이용한 다세포 스페로이드의 형성 및 추출칩을 제안하였다. 종래의 웰 플레이트와 플라스크는 작은 스페로이드 형성이 어렵고, 기존 마이크로칩은 고정된 세포포집 구조물을 이용하여 스페로이드 추출이 어려운 단점이 있다. 반면, 제안된 칩은 한시적 세포포집 구조물을 이용하여 스페로이드의 형성과 추출이 모두 용이한 장점이 있다. 50kPa 의 박막압력으로 형성된 세포포집 구조물에 145~155Pa 의 세포입력압력으로 유입되는 세포를 포집한 후, 24 시간 배양하여 스페로이드를 형성하였다. 또한, 박막압력 제거 후 5kPa 의 세포입력압력으로 추출된 스페로이드의 지름과 활성도는 각각 $197{\pm}11.7Bm$, $80.3{\pm}7.7%$로 측정되었다. 제안된 칩은 스페로이드의 균일한 형성과 안정적 추출이 용이하여 스페로이드의 후처리에 적용될 수 있다.

• Fisheries and Aquatic Sciences
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• 제8권3호
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• pp.185-187
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• 2005

We tested the in vivo ability of a DNA chip to detect virus-specific genes from virus-infected olive flounder Paralichthys olivaceus and rainbow trout Oncorhynchus mykiss. Target cDNA was obtained from total RNA of virus infected cell lines by reverse transcription (RT) and was labeled with fluorescent dye (Cy5-dUTP). The results show the successful detection of infectious hematopoietic necrosis virus (IHNV) and viral hemorrhagic septicaemia virus (VHSV) genes in the virus-infected fishes.

• 한국환경성돌연변이발암원학회지
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• 제26권1호
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• pp.1-6
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• 2006

To enhance our understanding of toxicity mediated through the pathway by which TCDD stimulates gene expression, we have investigated genes whose expressions are changed after treatment with TCDD and/or MNNG in human Chang liver cell. First, we treated with MNNG and TCDD for two weeks to transform human Chang liver cell. We obtained cell looks like to be transformed and compared the differential gene expression by using cDNA chip (Macrogen) which carrys genes related with signal transduction pathways, oncogenes and tumor suppressor genes, etc. We found that TCDD up- or down-regulated 203 and 111 genes including oncogenes and tumor suppressor genes in human Chang liver cell two fold or more, respectively. Second, we compared the differential gene expression after treatment with TCDD only by using cDNA chip (Superarray) which carrys genes related with cell cycle regulations, and found that TCDD up regulated genes related with cell proliferation as well as cell growth inhibition in human Chang liver cell two fold or more, respectively. These results suggest that toxicity induced by TCDD may reflect sustained alterations in the expression of many genes and that the changes reflect both direct and indirect effects of TCDD.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2006년도 추계학술대회 논문집 Vol.19
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• pp.300-301
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• 2006

We studied about new module technology to solve warpage problems that produce bending of cell in the LCD (Liquid crystal display). Characteristics of cell gap and glass bending of applying heat Panel's PAD part and cell at various temperature was investigated. When applies heat and compresses PAD party only in case of compressing COG(Chip on Glass), uniformity of cell gap that happen by glass bending by temperature of these compressing COG In the PAD party is decreased. However, in case of compress COG. glass bending of applying heat Panel's PAD part and cell at various temperature produced 20um. But, uniformity of cell gap was not decreased. Therefore, it is considered that applying heat Panel's PAD part and cell could decrease uniformity of cell gap and bending of glass.

• 전자공학회논문지C
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• 제36C권11호
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• pp.46-54
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• 1999

셀룰러 신경망 셀의 출력값은 각 셀의 초기 상태값에 따라서 국부적 최소점으로 안정화될 수 있으므로 출력값에 오류를 가져을 수 있다. 이에 본 논문에서는 각 셀의 초기 상태값에 관계없이 출력값이 전역적 최소점 도달하여 정확한 출력이 보장되도록 하는 어닐링 기능을 갖는 6×6 셀룰러 신경망을 설계하였다. 이 칩은 0.8㎛ CMOS 공정으로 설계하였다. 설계된 칩은 약 15,000여개의 트랜지스터로 구성되며 칩 면적은 약 2.89×2.89㎟이다. 설계된 회로를 이용한 윤곽선 추출 및 hole filling에 대한 시뮬레이션 결과에서 어닐링이 되지 않은 경우에서 출력값에 오류를 일으킬 수 있지만 어닐링 기능을 갖는 경우에는 오류가 발생하지 않는 것을 확인하였다. 시뮬레이션에서 어닐링 시간은 3μsec로 하였다.

• International Journal of Stem Cells
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• 제17권1호
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• pp.30-37
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• 2024

The lung is a complex organ comprising a branched airway that connects the large airway and millions of terminal gas-exchange units. Traditional pulmonary biomedical research by using cell line model system have limitations such as lack of cellular heterogeneity, animal models also have limitations including ethical concern, race-to-race variations, and physiological differences found in vivo. Organoids and on-a-chip models offer viable solutions for these issues. Organoids are three-dimensional, self-organized construct composed of numerous cells derived from stem cells cultured with growth factors required for the maintenance of stem cells. On-a-chip models are biomimetic microsystems which are able to customize to use microfluidic systems to simulate blood flow in blood channels or vacuum to simulate human breathing. This review summarizes the key components and previous biomedical studies conducted on lung organoids and lung-on-a-chip models, and introduces potential future applications. Considering the importance and benefits of these model systems, we believe that the system will offer better platform to biomedical researchers on pulmonary diseases, such as emerging viral infection, progressive fibrotic pulmonary diseases, or primary or metastatic lung cancer.

• ETRI Journal
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• 제30권6호
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• pp.826-832
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• 2008

The metal-ferroelectric-metal (MFM) capacitor in the ferroelectric random access memory (FeRAM) embedded RFID chip is used in both the memory cell region and the peripheral analog and digital circuit area for capacitance parameter control. The capacitance value of the MFM capacitor is about 30 times larger than that of conventional capacitors, such as the poly-insulator-poly (PIP) capacitor and the metal-insulator-metal (MIM) capacitor. An MFM capacitor directly stacked over the analog and memory circuit region can share the layout area with the circuit region; thus, the chip size can be reduced by about 60%. The energy transformation efficiency using the MFM scheme is higher than that of the PIP scheme in RFID chips. The radio frequency operational signal properties using circuits with MFM capacitors are almost the same as or better than with PIP, MIM, and MOS capacitors. For the default value specification requirement, the default set cell is designed with an additional dummy cell.

• 한국전기전자재료학회논문지
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• 제18권6호
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• pp.506-509
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• 2005

This paper presents the improved burn-in method for the reliability of SRAM in Multi Chip Package (MCP). Semiconductor reliability is commonly improved by the burn-in process. Reliability Problem is very significant in the MCP which includes over two chips in a package because the failure of one SRAM chip has a large influence on the yield and quality of the other chips such as Flash Memory, DRAM, etc. Therefore the quality of SRAM must be guaranteed. To improve the qualify of SRAM, we applied the improved wafer level burn-in process using multi cell selection method in addition to the previously used methods and it is found to be effective in detecting particular failures. Finally, with the composition of some kinds of methods, we achieved the high quality of SRAM in MCP.

• 정보통신설비학회논문지
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• 제8권2호
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• pp.64-71
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• 2009

In this paper, This thesis is cell phone for make CAS service be for hand joining broadcasting Create a way CAS Chip. PerSam issue card inside use Seed Key and algorithm make CID Key and record CAS Chip. PerSam member Card inside use Seed Key and algorithm make Subscriber Key after include Subscriber. Key CAS Chip for record CID Key register EMM. make CAS CHIP in accordance with issue CAS Chip. broadcast service entry be for hand treatment so make low bandwidth for joining massage and make increase a member.