• 제목/요약/키워드: case control studies

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International Law Perspectives of Deploying ROK Naval Power On Dokdo - Focus On Effective Control of Dokdo - (독도의 해군력 배치에 관한 국제법적 검토 및 발전방향 - 실효적 지배 개념을 중심으로-)

  • Kim, Nam-Gu
    • Strategy21
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    • 통권32호
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    • pp.97-122
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    • 2013
  • The basic stance of the Republic of Korea Ministry of Foreign Affairs was 'quiet diplomacy'. However, there had been demands for specific plans for practical protection of Dokdo. In 2011, Prime Minister Kim Hwang Sik mentioned that they are reviewing measures of stationing marines on Dokdo, while on August 10th, 2012, former president Lee Myung Bak visited Dokdo. The visit itself was meaningful as he was the first supreme commander to visit Dokdo. This paper studies on the necessity of naval power on Dokdo to maintain its effective control. The effective control must be done by a national organization in a peaceful and unimpaired method. If so, can stationing naval power, whether directly or indirectly, on Dokdo be considered a violation of 'peaceful' method? A 'peaceful' effective of control meas the right of sovereignty over a territory without other country's protest. In such terms, protecting a territory falls under practicing the right of sovereignty, and therefore does not violate 'peaceful'. In addition, looking at international cases such as Ligitan/Sipadan Case and Pedra Blanca Case, evidences such as 'navy activity', 'flyng ensign', and 'military communication facility installation' was used. In ter case of Yemen-Eritrea dispute over Hanish, methods on effective control over island and sea was also ruled by the installation of military posts and military surveillance activities. Thus, stationing naval power on Dokdo can be a way of maintaining effective control per international law. To station naval poer on Dokdo, Presidential Instruction 24 integrated Defense Guideline Enforcement Ordinance, which is domestic law, must be revised. Reason being, the Enforcement Ordinance states that the navy area of responsibility excluded Ullundo, where Dokdo is under jurisdiction of Ullungdim thus excluding navy control. In addition, considering the diplomatic situation, it is more fut to install navy radar site on Dokdo rather than 'stationing marines'. In other words, enforcing surveillance in the vicinity of Dokdo and installing radar site instead of stationing direct combatants is one way of practicing effective control without stimulating diplomatic disputes.

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Association between Trace Element and Heavy Metal Levels in Hair and Nail with Prostate Cancer

  • Karimi, Golgis;Shahar, Suzana;Homayouni, Nasim;Rajikan, Roslee;Bakar, Nor Faizah Abu;Othman, Mohd Sham
    • Asian Pacific Journal of Cancer Prevention
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    • 제13권9호
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    • pp.4249-4253
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    • 2012
  • While associations between trace elements and heavy metals with prostate cancer are still debatable, they have been considered as risk factors for prostate cancer. Thus, this study aimed to detect any links between selected minerals and heavy metals including Se, Zn, Cu, Mn and Fe with prostate cancer. A case control study was carried out among 100 subjects (case n=50, control n=50), matched for age and ethnicity. Trace elements and heavy metals level in hair and nail samples were determined by ICP-MS. Mean selenium levels in hair and nail of the cases were significantly lower as compared to controls. A similar trend was noted for zinc in both hair and nail samples, whereas the mean level of copper was significantly higher in cases than controls. Similar elevation was noted for iron and manganese (p<0.05 for all parameters). Low levels of selenium and zinc and high levels of copper, iron and manganese appear to be associated with the risk of prostate cancer. Further studies to elucidate the causal mechanisms and appropriate chemopreventive measures are needed.

Associations between Air Pollution and Asthma-related Hospital Admissions in Children in Seoul, Korea: A Case-crossover Study (환자교차 설계 방법을 적용한 소아천식 입원에 대한 도시 대기오염의 급성영향평가)

  • Lee, Jong-Tae
    • Journal of Preventive Medicine and Public Health
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    • 제36권1호
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    • pp.47-53
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    • 2003
  • Objectives : I used a case-crossover design to investigate the association between air pollution, and hospital admissions for asthmatic children under the age of 15 years in Seoul, Korea Methods : I estimated the changes in the levels of hospitalization risk from theinterquartile (IQR) increase in each pollutant concentrations, using conditional logistic regression analyses, with controls for weather information. Results : Using bidirectional control sampling, the results from a conditional logistic regression model, with controls for weather conditions, showed the estimated relative risk of hospitalization for asthma among children to be 1.04 (95% confidence interval (CI), 1.01-1.08) for particulate matter with an aerodynamic diameter less than or equal to 10m (IQR=40.4ug/m3); 1.05 (95% CI, 1.00- 1.09) for nitrogen dioxide (IQR=14.6ppb): 1.02 (95% CI,0.97-1.06) for sulfur dioxide (IQR=4.4ppb): 1.03 (95% CI, 0.99-1.08) for ozone (IQR=21.7ppb): and 1.03 (95% CI, 0.99-1.08) for carbon monoxide f10R=1.0ppm). Conclusions : This empirical analysis indicates the bidirectional control sampling methods, by design, would successfully control the confounding factors due to the long-term time trends of air pollution. These findings also support the hypothesis that air pollution at levels below the current ambient air quality standards of Korea is harmful to sensitive subjects, such as asthmatic children.

Multiple-Case Studies of Hand-on Breast Massage Techniques used by Breastfeeding Experts (산후 유방 마사지 손기술에 대한 다중사례분석)

  • Park, Hyunsoon;Cho, Insook;Kim, Min-Kyeong
    • Women's Health Nursing
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    • 제23권3호
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    • pp.155-165
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    • 2017
  • Purpose: The aim of this study was to understand the hand-on breast massage techniques used by well-known experts in breastfeeding clinics. Methods: A qualitative multiple-case design was applied that involved a feasibility test. Four experts sampling qualitative data collected by observing participants and in individual interviews were analyzed by content analysis, linking data to the propositions, and cross-case pattern matching. This study explored differences within and between cases, and the possibilities of replicating findings across cases. Thirty-nine postpartum women participated voluntarily in the feasibility test, which investigated the usability of four massage techniques. Results: The four techniques showed considerable similarities in terms of the application of stimulation to the breast base and increased flexibility of the wired flexible body, which was the core mechanism underlying the techniques. The breast management strategies were consistent with existing practice guidelines with the exception of using cold cabbage to control engorgement pain. There was insufficient scientific evidence for supporting the massage techniques used by the experts. All of the techniques showed 100% education completeness, but application rates were higher for self-control-oriented techniques. Conclusion: The massage techniques applied by experts in breastfeeding were based on hypotheses and self-control techniques are feasible to apply in practice.

A Review of Scalp Acupuncture on Patients with Insomnia -Focusing on Chinese Journals- (불면의 두침치료에 대한 임상논문 고찰 -1994년부터 2011년까지 중국 논문을 중심으로-)

  • Ryu, Chun-Gil;Kim, Soo-Jung;Cho, A-Ram;Seo, Joo-Hee;Jeong, Seong-Sik;Lee, Ji-Su;Sung, Woo-Yong
    • Journal of Oriental Neuropsychiatry
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    • 제23권1호
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    • pp.17-29
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    • 2012
  • Objectives : The study was designed to evaluate the effects of scalp acupuncture treatment on patients with insomnia in China. Methods : A journal search was performed using China National Knowledge Infrastructure(CNKI) from 1994 to 2011. Key words used within the search were 'insomnia' and 'scalp acupuncture'. Results : 19 studies were selected. 9 RCTs and 2 case control studies showed that scalp acupuncture therapy reported better results than routine acupuncture, western medicine, and herbal medicine therapy. 8 case reports described a significant improvement in patients with insomnia by scalp acupuncture. Conclusions : There have been many studies regarding scalp acupuncture on patients with insomnia in China and these studies can be applied to clinical practices within Korea.

Adverse Events of Electronic Moxibustion Treatment for Knee Osteoarthritis: Case Reports and a Literature Review

  • Oh, Yoona;Lee, Jisun;Kim, Yeonhak;Kim, Eun Seok;Kim, Kun Hyung;Lee, Byung Ryul;Yang, Gi Young
    • Journal of Acupuncture Research
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    • 제39권1호
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    • pp.29-35
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    • 2022
  • Background: Electronic moxibustion has the advantage of temperature control and maintenance, and overcomes the limitations of the existing moxibustion process without the use of the combustion process. However, as the application of electronic moxibustion in clinical practice has increased, safety issues are emerging. Methods: Clinical cases of electronic moxibustion treatment for knee osteoarthritis where burns occurred were collected. In addition, adverse events reported in clinical studies using electronic moxibustion for patients with knee osteoarthritis were collected from studies retrieved from Korean and international databases. Results: There were 3 cases of superficial 2nd degree burns retrospectively collected through chart reviews. Among the selected 5 studies for literature review, 2 studies reported adverse events which were burns milder than those reported in these 3 cases in this retrospective case review. Conclusion: Since the risk of superficial 2nd degree burn was discovered in the cases reviewed, further research on safe electronic moxibustion treatment is required without compromising the effectiveness of moxibustion.

Discovering Gene-Environment Interactions in the Post-Genomic Era

  • Naidoo, Nirinjini;Chia, Kee-Seng
    • Journal of Preventive Medicine and Public Health
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    • 제42권6호
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    • pp.356-359
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    • 2009
  • In the more than 100 genome wide association studies (GWAS) conducted in the past 5 years, more than 250 genetic loci contributing to more than 40 common diseases and traits have been identified. Whilst many genes have been linked to a trait, both their individual and combined effects are small and unable to explain earlier estimates of heritability. Given the rapid changes in disease incidence that cannot be accounted for by changes in diagnostic practises, there is need to have well characterized exposure information in addition to genomic data for the study of gene-environment interactions. The case-control and cohort study designs are most suited for studying associations between risk factors and occurrence of an outcome. However, the case control study design is subject to several biases and hence the preferred choice of the prospective cohort study design in investigating geneenvironment interactions. A major limitation of utilising the prospective cohort study design is the long duration of follow-up of participants to accumulate adequate outcome data. The GWAS paradigm is a timely reminder for traditional epidemiologists who often perform one- or few-at-a-time hypothesis-testing studies with the main hallmarks of GWAS being the agnostic approach and the massive dataset derived through large-scale international collaborations.

Damping of Inter-Area Low Frequency Oscillation Using an Adaptive Wide-Area Damping Controller

  • Yao, Wei;Jiang, L.;Fang, Jiakun;Wen, Jinyu;Wang, Shaorong
    • Journal of Electrical Engineering and Technology
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    • 제9권1호
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    • pp.27-36
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    • 2014
  • This paper presents an adaptive wide-area damping controller (WADC) based on generalized predictive control (GPC) and model identification for damping the inter-area low frequency oscillations in large-scale inter-connected power system. A recursive least-squares algorithm (RLSA) with a varying forgetting factor is applied to identify online the reduced-order linearlized model which contains dominant inter-area low frequency oscillations. Based on this linearlized model, the generalized predictive control scheme considering control output constraints is employed to obtain the optimal control signal in each sampling interval. Case studies are undertaken on a two-area four-machine power system and the New England 10-machine 39-bus power system, respectively. Simulation results show that the proposed adaptive WADC not only can damp the inter-area oscillations effectively under a wide range of operation conditions and different disturbances, but also has better robustness against to the time delay existing in the remote signals. The comparison studies with the conventional lead-lag WADC are also provided.

Hybrid Fuzzy PI-Control Scheme for Quasi Multi-Pulse Interline Power Flow Controllers Including the P-Q Decoupling Feature

  • Vural, Ahmet Mete;Bayindir, Kamil Cagatay
    • Journal of Power Electronics
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    • 제12권5호
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    • pp.787-799
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    • 2012
  • Real and reactive power flows on a transmission line interact inherently. This situation degrades power flow controller performance when independent real and reactive power flow regulation is required. In this study, a quasi multi-pulse interline power flow controller (IPFC), consisting of eight six-pulse voltage source converters (VSC) switched at the fundamental frequency is proposed to control real and reactive power flows dynamically on a transmission line in response to a sequence of set-point changes formed by unit-step reference values. It is shown that the proposed hybrid fuzzy-PI commanded IPFC shows better decoupling performance than the parameter optimized PI controllers with analytically calculated feed-forward gains for decoupling. Comparative simulation studies are carried out on a 4-machine 4-bus test power system through a number of case studies. While only the fuzzy inference of the proposed control scheme has been modeled in MATLAB, the power system, converter power circuit, control and calculation blocks have been simulated in PSCAD/EMTDC by interfacing these two packages on-line.

The Relationship between Oral Disease and Respiratory Disease in the Elderly (임상가를 위한 특집 1 - 노년의 구강 질환과 호흡기 질환의 관계)

  • Jeong, Jin-Seok;Heo, Seok-Mo
    • The Journal of the Korean dental association
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    • 제51권9호
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    • pp.494-500
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    • 2013
  • Recently, several researches indicated the relationship between oral condition and respiratory disease such as pneumonia and chronic obstructive pulmonary disease (COPD). Respiratory disease is known as common chronic disease in the elderly increasing mortality and morbidity. In this study, we have reviewed the association between oral disease and respiratory disease in the elderly. The related data were searched and collected from abroad and domestic studies. The studies included the randomized controlled clinical trials (RCTs), longitudinal, cohort, case-control, and systematic review studies. With the data from the studies, we concluded that poor oral hygiene or periodontal disease can influence the pneumonia in the elderly. Further studies will be needed to investigate the association between oral disease and COPD.