• International Journal of Quality Innovation
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• 제4권1호
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• pp.191-204
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• 2003

The target costing technique, mathematically discussed by Sauers, only uses the $C_p index along with Taguchi loss function and $\bar{X}$-P control charts to setup goal control limits. The new specification limits derived from Taguchi loss function is linked through the $C_p value to $\bar{X}$-P control charts to obtain goal control limits. Studies have shown that the point estimator of the $C_p index, $C_p, could vary from time to time due to the sampling error. The suggested approach is to use confidence intervals, especially the lower confidence intervals, to replace the point estimator. Therefore, an improvement on target costing technique is presented by applying the lower confidence interval of the $C_p index and using both Taguchi and Spiring's loss functions together with $\bar{X}$-P charts to make this technique more robust in practice. An example is also provided to illustrate how the improved target costing technique works.

• 대한수학회지
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• 제56권6호
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• pp.1463-1474
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• 2019

Let C be a nonsingular projective curve of genus ${\geq}2$ over an algebraically closed field of characteristic 0. For a point P in C, the Weierstrass semigroup H(P) is defined as the set of non-negative integers n for which there exists a rational function f on C such that the order of the pole of f at P is equal to n, and f is regular away from P. A point P in C is referred to as a weak Galois-Weierstrass point if P is a Weierstrass point and there exists a Galois morphism ${\varphi}:C{\rightarrow}{\mathbb{p}}^1$ such that P is a total ramification point of ${\varphi}$. In this paper, we investigate the number of weak Galois-Weierstrass points of which the Weierstrass semigroups are generated by two positive integers.

• Nonlinear Functional Analysis and Applications
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• 제27권2호
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• pp.271-287
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• 2022

In this article, we shall prove a common fixed point theorem for two weakly compatible self-maps 𝒫 and 𝔔 on a dislocated metric space (M, d^*) satisfying the following ξ-weakly expansive condition: d^*(𝒫c, 𝒫d) ≥ d^* (𝔔c, 𝔔d) + ξ(∧(𝔔c, 𝔔d)), ∀ c, d ∈ M, where $${\wedge}(Qc,\;Qd)=max\{d^*(Qc,\;Qd),\;d^*(Qc,\;\mathcal{P}c),\;d^*(Qd,\;\mathcal{P}d),\;\frac{d^*(Qc,\;\mathcal{P}c){\cdot}d^*(Qd,\;\mathcal{P}d)}{1+d^*(Qc,\;Qd)},\;\frac{d^*(Qc,\;\mathcal{P}c){\cdot}d^*(Qd,\;\mathcal{P}d)}{1+d^*(\mathcal{P}c,\;\mathcal{P}d)}\}$$. Also, we have proved common fixed point theorems for the above mentioned weakly compatible self-maps along with E.A. property and (CLR) property. An illustrative example is also provided to support our results.

• 한국응용곤충학회지
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• 제30권2호
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• pp.138-143
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• 1991

배추흰나비 P. rapae와 P. brassicae GV의 DNA성상과 이를 기초로한 상동성을 검정한 결과 Tm값에서는 P. rapae GV DNA는 $83.7^{\circ}C$이고, P. brassicae GV DNA의 경우는 $84.0^{\circ}C$로 G+C 함량은 전자가 35.5%, 후자가 35.9%였다. 그리고 제한산소처리에 의한 DNA의 분석에서는 P. Rapae GV의 genome의 크기는 103 kb, P. brassicae GV DNA는 108kb로 나타났으며, 두바이러스 간의 상동성은 97.0%였다.

• Applied Biological Chemistry
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• 제46권3호
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• pp.171-175
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• 2003

실험실 배양 조건에서는 발현되지 않는 대장균 K-12의 endochitinase 유전자(yheR)를 PCR로 증폭하여 pET28c와 pQE9벡터에 각각 클로닝 하였다. yheB유전자를 가진 pET28c와 pQE9 벡터를 함유한 대장균에서 생산된 endochitinase는 생장배지 내로 일부 분리되었다. 과량 생산된 endochitinase를 His-affinity 크로마토그래피와 DE-52 크로마토그래피로 부분 정제하였으며 SDS-PAGE에 의한 단백질의 분자량은 약 97,000 이었다. 정제된 효소의 최적 pH는 6이었으며 최적 온도는 $40^{\circ}C$이었다.

• 미생물학회지
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• 제33권3호
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• pp.165-169
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• 1997

병원하수에서 분리한 gentamicin 저항성 세균으로부터 aacC2 유전자를 가지고 있는 R 플라스미드 pGM5와 pGM6를 선발하였다. 이들 플라스미드에서 gentamicin 저항성 유전자를 포함하는 부분을 pUC18의 BamHI 자리에 클로닝하여 재조합 플라스미드 pSY5와 pSY6를 각각 얻었다. 재조합 플라스미드의 삽입된 부분에 대한 제한효소 지도를 통해 Tn3 염기서열이 aacC2 유전자의 상류부위에 위치하는 것을 알았다. 재조합 플라스미드의 gentamicin에 대한 민감성의 비교를 통해 Tn3의 bla 유전자 부분과 3'역행중복 부위의 염기서열이 gentamicin 저항성 유전자의 발현에 중요한 역할을 담당하고 있었다.

• 대한수학회보
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• 제53권2호
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• pp.325-334
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• 2016

In this paper, a boundary version of the Schwarz lemma is investigated. We take into consideration a function $f(z)=z+c_{p+1}z^{p+1}+c_{p+2}z^{p+2}+{\cdots}$ holomorphic in the unit disc and $\|\frac{f(z)}{{\lambda}f(z)+(1-{\lambda})z}-{\alpha}\|$ < ${\alpha}$ for ${\mid}z{\mid}$ < 1, where $\frac{1}{2}$ < ${\alpha}$ ${\leq}{\frac{1}{1+{\lambda}}}$, $0{\leq}{\lambda}$ < 1. If we know the second and the third coefficient in the expansion of the function $f(z)=z+c_{p+1}z^{p+1}+c_{p+2}z^{p+2}+{\cdots}$, then we can obtain more general results on the angular derivatives of certain holomorphic function on the unit disc at boundary by taking into account $c_{p+1}$, $c_{p+2}$ and zeros of f(z) - z. We obtain a sharp lower bound of ${\mid}f^{\prime}(b){\mid}$ at the point b, where ${\mid}b{\mid}=1$.

• 대한화학회지
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• 제47권5호
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• pp.460-465
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• 2003

p53 유전자의 변이는 다양한 인체암 중 가장 일반적인 유전자적 변화로 알려져 있으며, 양성에서 악성 대장암으로 전이되는 과정에서 연관이 있는 것으로 알려져 있다. 본 연구에서는 PCR-SSCP와 DHPLC를 이용하여 대장암 환자의 조직에서 p53 유전자의 엑손 5-8에서 돌연변이를 분석하였다. SSCP에서는 50개의 샘플중 엑손 5에서 C13109>T 형태의 돌연변이가 7례가(14%) 발견되었고, DHPLC에서는 C13109>T 7례와 C13202>A, C13204>G 형태의 돌연변이 2례, 모두 9례의(18%) 변이가 검출되었다. DHPLC 분석법을 이용하여 SSCP에서 발견하지 못했던 2례(4%)의 변이를 더 발견하였다. 최종적으로 염기서열분석법을 통해 위의 결과를 확인하였고, p53 돌연변이 검출법으로 SSCP보다 DHPLC가 더 감도가 좋고 효과적인 검출법임을 확인하였다.

• 대한물리치료과학회지
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• 제15권2호
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• pp.1-13
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• 2008

Background: This study had been carried out with 18 ischemic stroke patients as its object for about eight months from October, 2006 to May, 2007 in order to observe the recovery of motor function and the change of important blood factors according to the different quantitative exercises. Methods: Subjects were assigned randomly either experimental group (n＝19) or the control group (n＝19), when the study began the halfway on this study dropout 20 patients, and final subjects remained experimental group's 9 patients and control group's 9 patients. Both groups received thermotherapy and functional electrical stimulation (FES), also taken different quantitative exercise therapy (experimental group 180 minutes, control group 80 minutes). Subjects were assessed for upper and lower extremities motor function Fugl－Meyer Scale; FMS), blood test (white blood count; WBC, low density lipoprotein －cholesterol; LDL-C, high density lipoprotein-cholesterol; HDL-C, Troponin) during pretest, after 2 months, after 3 months. Results: The results of this study were as follows; 1. FMS has no statistically significant difference with intergroup(p>.05). But there was a statistically significant difference with each groups (p<.05). 2. WBC has no statistically significant difference with intergroup (p>.05). But there was a statistically significant difference in control group (p<.05), without experimental group (p>.05). 3. LDL-C has no statistically significant difference with intergroup (p>.05). But there was a statistically significant difference in control group (p<.05), without experimental group (p>.05). 4. HDL-C has no statistically significant difference with intergroup (p<.05). But there was a statistically significant difference with each groups (p>.05). 5. Troponin Ⅰ has no statistically significant difference with intergroup (p>.05). Also there was no statistically significant difference with each groups (p>.05). Conclusion: These findings suggest that different quantitative exercises has no effect on FMS, LDL-C, HDL-C, WBC, Troponin Ⅰ with ischemic stroke patients. But the treatment period that there's less correlation between the recovery of motor function and the different quantitative exercise, also less correlation between the change of important blood factors and the different quantitative exercises with ischemic stroke patients.

• 한국식품영양과학회지
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• 제28권3호
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• pp.710-721
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• 1999

This study was conducted to investigate the hematological characteristics and risk factors of hypercholesterolemia(HC) in Korean. 344 adult men who took the annual health check ups at D or J hospitals were participated in this cross sectional study. The subjects were grouped by plasma total cholesterol level into three groups: normal cholesterolemic(n=139), borderline hypercholesterolemic (n=93) and hypercholesterolemic(n=112) groups. The data of systolic and diastolic blood pressure (SBP/DBP), hemoglobin, plasma glucose, albumin and cholesterol levels were collected from medical records. The levels of plasma triglyceride(TG), HDL C, phospholipid, insulin, apo A and apo B were measured. The levels of plasma LDL C, VLDL C and atherogenic index(AI) were calculated. The subjects with HC had significantly higher SBP and DBP, albumin, TG, phospholipid, HDL C, LDL C, VLDL C and apo B level than those of the normal subjects. The relative and attributable risks on HC were 1.59 and 0.18 for hypertension(SBP/DBP$\geq$160/95), 2.08 and 0.35 for hypertriglyceridemia (TG $\geq$400mg/dl). Plasma total cholesterol level was positively correlated with several hematologic parameters: age(r=0.1242, p<0.05), DBP(r=0.1194, p<0.05), albumin(r=0.2029, p<0.001), plasma TG(r= 0.3829, p<0.001), phospholipid(r=0.6036, p<0.001), LDL C(r=0.8572, p<0.001), HDL C(r=0.2399, p< 0.001), AI(r=0.3116, p<0.001), apo B(r=0.2602, p<0.05) and Lp(a)(r=0.1372, p<0.05). However, plasma total cholesterol level was negatively correlated with the levels of Apo A1(r= 0.2922, p<0.001), and ABR(r= 0.3598, p<0.001).