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Phytochemical Standardization and Anti-Anxiety (Izterab-e-Nafsani) study of Aftimoon Hindi (Cuscuta reflexa Roxb.) on An Animal Model

  • Ara, Irfat;Kalam, Mohd Afsahul;Maqbool, Mudasir;Zehravi, Mehrukh
    • CELLMED
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    • v.11 no.3
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    • pp.14.1-14.9
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    • 2021
  • Background: Cuscuta reflexa Roxb is a member of the Cuscutaceae family, and in Unani medicine, it is known as Aftimoon. It is a parasitic plant that can be found growing abundantly on various host plants in India up to 3000 metres in altitude during the rainy season. Unani physicians have been using it for years to cure a variety of illnesses, including psychiatric illnesses like melancholia, schizophrenia, and epilepsy. It has been used to cure hepatitis, palpitations, and skin disorders, among other things. Objective of the study: To evaluate anti-anxiety effect of Cuscuta reflexa Roxb in Swiss Albino mice of either sex. Materials and Methods: A total of 24 Swiss Albino mice weighing 25-35 g were used in this study. Animals were chosen at random and held in their cages for at least 7 days in a standard setting. Group A was given regular saline as a vehicle, Group B was given a hydro alcoholic extract of the lower dose of the test drug, Group C was given a hydro alcoholic extract of the higher dose of the test drug, and Group D was given the standard drug Diazepam 5 mg/kg orally. Aftimoon as hydro alcoholic extract (200 mg/kg and 400 mg/kg body wt.) was given in single and double doses and observed for 7 days. Results: For each parameter in each category, mean and standard deviations were computed. For multiple group comparisons, a one-way ANOVA was used, followed by Turkey's post hoc test. (p<0.05) was used as the significance standard. Conclusion: These results advocate that the Aftimoon as double dose (400 mg/kg body wt.) revealed anti-anxiety effect similar to standard drug.

Health Promotion Behavior and Adaptation to College of Nursing Students in the COVID era (코로나 시대 간호대학생의 건강증진행위와 대학생활적응)

  • Kim, Jiyoung
    • Journal of the Korean Applied Science and Technology
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    • v.39 no.5
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    • pp.683-691
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    • 2022
  • The purpose of this study was to identify the relationship between health promotion behavior and adaptation to college of nursing students and investigate the factors influencing adaptation to college in the COVID era. The subjects were consisted of 191 nursing students from J University in province C. Data were analyzed based on frequency, percentile, mean, Pearson's correlations, and multiple regressions. Health promotion behavior and college adjustment in nursing students showed significant positive correlations with each other. Health promotion behavior had the strongest influence on nursing students' adaptation to college, followed by health level; these factors accounted for 19.9% of the total variance in adaptation to college among nursing students(Adj. R2=.199, p<.001). Overall adaptation to college can be improved by health promotion behavior enhancement program.

The Influence of Confidence in Performance and Learning Flow on Satisfaction with Practicum Programs in Face-to-Face and Online Classes amid COVID-19 (COVID-19 상황으로 인한 대면과 온라인 수업에서 간호대학생의 수행자신감, 학습몰입도가 실습 만족도에 미치는 영향)

  • Jeong, Jin Hee;Lee, Hye Kyung
    • Journal of the Korean Society of School Health
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    • v.35 no.1
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    • pp.11-21
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    • 2022
  • Purpose: This study investigated the relationship between satisfaction with fundamental nursing skills practicum, confidence in fundamental nursing skills performance and learning flow, and examined factors influencing satisfaction with practicum programs of fundamental nursing skills in face-to-face and online classes for nursing students amid COVID-19. Methods: The subjects of the study were 229 junior nursing students from two colleges of nursing located in D and C city, respectively. The collected data were analyzed with descriptive statistics, independent t-test, ANOVA, Kruskal-Wallis test, Pearson's correlation and hierarchical multiple regression, using SPSS/WINdows 23.0. Results: The subjects' satisfaction with practicum showed a high positive correlation with confidence in performance (r=.55, p<.001) and learning flow (r=.70, p<.001) in face-to-face classes, and their satisfaction with practicum showed a high positive correlation with confidence in performance (r=.56, p<.001) and learning flow (r=.73, p<.001) in online classes. The factors affecting the subjects' satisfaction with practicum were learning flow (β=.51, p<.001) and confidence in performance (β=.30, p<.001) for face-to-face classes, and motivation for application (β=.14, p=.034), learning flow (β=.58 p<.001) and confidence in performance (β=.19, p=.015) for online classes. These factors explained 53% and 60% of the satisfaction with practicum in face-to-face classes (F=23.07, p<.001) and online classes (F=20.66, p<.001), respectively. Conclusion: Learning flow and confidence in performance should be considered when developing learning strategy programs to improve nursing students' satisfaction with fundamental nursing skills practicum in both face-to-face and online classes.

Quality of Life in Colorectal Cancer Patients at Home 5-Fluorouracil Chemotherapy with Disposable Elastomeric Infusion Pumps (일회용 약물주입기로 가정에서 항암치료 중인 대장암 환자의 삶의 질)

  • Lee, Chung Eun;Kim, Na Young;Park, Me Hee;Lee, Yoon Jung;Kim, Jin Ra;Baek, Min Ju;Kim, Hyo Jin;Byun, Eun Sung;Kil, Yun Kyung;Kim, Heejung
    • Journal of Korean Clinical Nursing Research
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    • v.28 no.1
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    • pp.76-87
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    • 2022
  • Purpose: The purpose of this study was to examine the psychological distress related to quality of life (QoL) of patients with colorectal cancer receiving 5-fluorouracil (5-FU) chemotherapy at home with disposable Elastomeric infusion pumps. Methods: In this study, 179 colorectal outpatients were recruited between September 2019 and January 2021. National Cancer Center Psychological Symptom Inventory scores, general self-efficacy, and the EORTC QLQ-C30 scores were measured. Data were analyzed using Independent t-test, One-way ANOVA with Bonferroni post hoc analysis, and hierarchical multiple linear regression with the SPSS/WIN 26.0 programs. Results: The overall prevalence of psychological distress was 52.0% in colorectal patients. In multiple regression, psychological distress (β=-.20, p=.005), appetite loss (β=-.20, p=.001), chemotherapy cycles (β= .19, p=.002), fatigue (β=-.16, p=.035), physical functioning (β=-.16, p=.024), and emotional functioning (β=-.15, p=.025) were significant factors of QoL, and the final model explained 45.0% of the total variance of QoL. Conclusion: Supporting patients toward decreased psychological distress and increased physical and emotional functioning, especially in the first or second cycle of chemotherapy, could be used to improve their QoL. To consider the thresholds for clinical importance, it is necessary to increase the interpretation of psychological distress in clinical practice and further research.

Effects of COVID-19 Knowledge Level and Infection Control Fatigue and Stress on Infection Control Performance (코로나-19 지식수준과 감염관리 피로도 및 스트레스가 감염관리 수행도에 미치는 영향)

  • Kim, Da-Som;Bae, Seok-Hwan
    • Journal of radiological science and technology
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    • v.45 no.3
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    • pp.263-272
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    • 2022
  • This study investigated small and medium-sized hospital workers' knowledge of COVID-19, the infection-control-related fatigue and stress levels, and the factors that impacted their performance during the COVID-19 pandemic. Using a cross-sectional design, data were collected from 137 hospital workers from four small and medium-sized hospitals in S and C cities. Data were analyzed using descriptive statistics, a t-test, analysis of variance(ANOVA), Pearson's correlation coefficient, and multiple linear regression analysis. Small and medium-sized hospital workers' knowledge of COVID-19 revealed a correct answer rate of 66%. An average of 3.00 points out of 4 for infection control performance and 3.32 and 3.17 points out of 5 for infection-control-related fatigue and stress, respectively, were found. The level of knowledge regarding COVID-19 significantly differed by age and marriage (p<0.05), while infection control performance significantly differed by age, marriage, and infection control education experience (p<0.05). Infection-control-related fatigue and stress differed depending on the COVID-19 control education experience, economic and social prejudice, and fear of discrimination. There were positive correlations between knowledge and infection control performance, and infection control performance and infection-control-related fatigue and stress (p<0.001). This study showed that the factors that affected small and medium-sized hospital workers' performance included knowledge of "environmental management," "difficulties due to new role requirements," "presence or absence of infection education experience," "job type," and "age." These results suggest that practical and detailed education programs should be systematically developed and implemented for effective infection control.

Effects of Hospital Ethical Climate and Communication Self-Efficacy on Nursing Cares Left Undone among Nurses (간호사의 병원윤리풍토와 의사소통 자기효능감이 미완료간호에 미치는 영향)

  • Noh, Yoon Goo;Sim, Bong Hee;Lee, Eun Su
    • Korean Journal of Occupational Health Nursing
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    • v.32 no.1
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    • pp.20-29
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    • 2023
  • Purpose: This study aimed to identify the effects of hospital ethical climate and communication self-efficacy on nursing care left undone. Methods: The participants were 142 nurses working in a general hospital. Data were collected from July 18 to August 30, 2021. Data were analyzed by t-test, ANOVA, Pearson correlation, and multiple regression analysis using the SPSS/WIN 25.0 program. Results: (a) The mean value of hospital ethical climate was 3.54±0.41, communication self-efficacy was 5.03±0.81, and the sum of nursing cares left undone was 3.68±3.14. (b) Nursing cares left undone had a negative correlation with hospital ethical climate(r=-.25, p=.003) but not with communication self-efficacy (r=-.13, p=.116). (c) Factors that affected nursing cares left undone included education (≥master) (β=.23, p=.005), marital status (single) (β=-.19, p=.018), age (26~27) (β=-.18, p=.022), and hospital ethical climate (β=-.18, p=.029); the explanation power was 18.0% (F=8.66, p<.001). Conclusion: Our study shows that hospital ethical climate plays a significant role in nursing cares left undone of nurses. It is important to strengthen hospital ethical climate to lower the incidence of nursing cares left undone. These results may serve as basic data to help develop strategies for reducing the incidence of nursing cares left undone.

Corrosion Behavior Optimization by Nanocoating Layer for Low Carbon Steel in Acid and Salt Media

  • Ahmed S. Abbas;Bahaa Sami Mahdi;Haider H. Abbas;F.F. Sayyid;A.M. Mustafa;Iman Adnan Annon;Yasir Muhi Abdulsahib;A.M. Resen;M. M. Hanoon;Nareen Hafidh Obaeed
    • Corrosion Science and Technology
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    • v.22 no.1
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    • pp.21-29
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    • 2023
  • In this paper, a SiC nano electroless nickel plating layer with excellent corrosion resistance was fabricated using the Taguchi method. The electroless plated low carbon steel was subjected to tests to examine the influence of corrosive media, microhardness, and corrosion rate on the corrosion resistance of this alloy. Three different corrosive media (HCl, Na2SO4, and NaCl) at various temperatures (80, 90, and 100 ℃) were used, and at three different times (40, 80, and 120 min.) with a speed of stirring equal to 500 rpm. The results of microhardness were found from 134.276 HV to 278.578 HV at various conditions, while the corrosion rate results were obtained from 0.89643 mpy to 7.12571 mpy at different circumstances. Corrosion, and mechanical characteristics were explained using Taguchi design. Taguchi technique was used to account for all possible combinations of elements in order to conduct a complete study. Models that link the response and procedure parameters were developed using the results of these tests, and the analysis of variance was utilized to validate these models (ANOVA). For maximum efficiency, a function called "desirability" was applied to all responses at once.

Effects of different calcium-silicate based materials on fracture resistance of immature permanent teeth with replacement root resorption and osteoclastogenesis

  • Gabriela Leite de Souza;Gabrielle Alves Nunes Freitas;Maria Tereza Hordones Ribeiro;Nelly Xiomara Alvarado Lemus;Carlos Jose Soares;Camilla Christian Gomes Moura
    • Restorative Dentistry and Endodontics
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    • v.48 no.2
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    • pp.21.1-21.15
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    • 2023
  • Objectives: This study evaluated the effects of Biodentine (BD), Bio-C Repair (BCR), and mineral trioxide aggregate (MTA) plug on the fracture resistance of simulated immature teeth with replacement root resorption (RRR) and in vitro-induced osteoclastogenesis. Materials and Methods: Sixty bovine incisors simulating immature teeth and RRR were divided into 5 groups: BD and BCR groups, with samples completely filled with the respective materials; MTA group, which utilized a 3-mm apical MTA plug; RRR group, which received no root canal filling; and normal periodontal ligament (PL) group, which had no RRR and no root canal filling. All the teeth underwent cycling loading, and compression strength testing was performed using a universal testing machine. RAW 264.7 macrophages were treated with 1:16 extracts of BD, BCR, and MTA containing receptor activator of nuclear factor-kappa B ligand (RANKL) for 5 days. RANKL-induced osteoclast differentiation was assessed by staining with tartrate-resistant acid phosphatase. The fracture load and osteoclast number were analyzed using 1-way ANOVA and Tukey's test (α = 0.05). Results: No significant difference in fracture resistance was observed among the groups (p > 0.05). All materials similarly inhibited osteoclastogenesis (p > 0.05), except for BCR, which led to a lower percentage of osteoclasts than did MTA (p < 0.0001). Conclusions: The treatment options for non-vital immature teeth with RRR did not strengthen the teeth and promoted a similar resistance to fractures in all cases. BD, MTA, and BCR showed inhibitory effects on osteoclast differentiation, with BCR yielding improved results compared to the other materials.

The Effect of Warm Scarf on Postoperative Xerostomia and Sore Throat in Colon Cancer Patients (대장암 수술 후 온열 목 마스크 적용이 구강건조와 인후통에 미치는 효과)

  • Choi, Song Yi;Lee, Ga Eun;Yoon, Bo Ra;Yoon, Ji Sun;Chung, Seo Young
    • Journal of Korean Clinical Nursing Research
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    • v.29 no.1
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    • pp.67-74
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    • 2023
  • Purpose: This study aimed to identify the effect of warm scarf on xerostomia and sore throat in postoperative colon cancer patients. Methods: A total of 40 participants with colon cancer who underwent colon cancer operation over 2hours were included from C University hospital in Seoul. The number of experimental group and control group is each 20 calculated by G*Power, and they were assigned by using nonequivalent control group no-synchronized design. In the experimental group, a warm scarf was applied to the neck for 120 minutes from entering the recovery room after the colorectal cancer surgery was completed. In the experimental group and the control group, xerostomia and sore throat were measured twice at 60-minute intervals. The degree of xerostomia was measured through the degree of wetness of the absorbent paper in mm, and the degree of sore throat was measured through the NRS (Numeral Rating Scale). Data were collected using self-administered questionnaires from August 2018 to September 2020 and were analyzed using IBM SPSS/WIN 21.0 Descriptive statistics, x2 test, Fisher's exact test, t-test were used to determine the participant's characteristics. The effect of warm scarf on xerostomia and sore throat were separately estimated by Repeated Measures ANOVA. Results: The experimental group showed significant decrease of xerostomia and sore throat as time goes (p<.001). Conclusion: Results indicate that warm scarf on xerostomia and sore throat in postoperative colon cancer patients is helpful method for relieving side effect of tracheal intubation.

A Study on the Analysis of Nurses' Perception of the Fourth Industrial Revolution and the Importance and Performance of Future Core Nursing Competencies in a Tertiary Hospital (일 상급종합병원 간호사의 4차 산업혁명에 대한 인식 및 미래핵심간호역량 중요도-실행도 분석)

  • Kwon, Chi Hye;Kim, Mi Soon
    • Journal of Korean Clinical Nursing Research
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    • v.29 no.1
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    • pp.95-106
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    • 2023
  • Purpose: This study is descriptive survey research on the analysis of nurses' perception of the 4th industrial revolution and the importance and performance of future core nursing competencies in a tertiary hospital located in Seoul. Methods: Data were collected from 149 nurses with more than a year of work experience and analyzed using descriptive statistics, t-test, one-way ANOVA, and Importance Performance Analysis(IPA) with the IBM SPSS/WIN 25.0 program. Results: The nurses' perception of the 4th industrial revolution was 3.23±0.71 out of 5 points. The importance of future core nursing competencies was 4.31±0.48, and the performance of it was 3.47±0.54. The analysis results of IPA showed that A (area of continuous maintenance) included critical thinking, problem-solving skills, teamwork and collaboration, evidence-based practice, communication, quality improvement and safety, professionalism, self-regulation and self-management, and personal literacy. The specific competencies were not included in B (area of priority improvement). Creativity, informatics, healthcare policy, leadership, research ability, and continuing education were included in C (area of progressive improvement). Knowledge and patient-centered care, ability to manage resources as well as professional, legal, and ethical responsibility were included in D (area of overinvestment). Conclusion: The nurses seemed not to be fully prepared for the 4th industrial revolution. However, they were well aware of the importance of the future core nursing competencies. Therefore, if nurses increase the performance of core competencies in order of priority according to the IPA results, they will be able to independently lead the changing nursing field.