• The Journal of Korean Institute of Communications and Information Sciences
• /
• v.35 no.3C
• /
• pp.302-313
• /
• 2010

In this paper, we propose an enhanced AGC (Automatic Gain Control) structure and P-SCH detection method for initial cell search in 3GPP (3rdGenerationPartnershipProject) LTE (Long Term Evolution) FDD(Frequency Division Duplex) / TDD (Time Division Duplex) dual mode system. Since TDD frame structure consists of uplink subframe and downlink subframe, conventional AGC structure causes P-SCH detection performance degradation by increase of AGC variation due to signal power difference between uplink and downlink subframe. Also, P-SCH detection performance is degraded by distortion of P-SCH correlation characteristic in frequency offset and multipath fading channel environments. Therefore, we propose an AGC structure which can minimize P-SCH detection performance degradation with stable operation in 3GPP LTE TDD mode as well as FDD mode. Also we propose a P-SCH detection method which can reduce distortion of correlation chareteristics in frequency offset and multipath fading environments and obtain good P-SCH detection performance. Simulation results show that the proposed AGC structure and P-SCH detection method have stable AGC operation and excellent P-SCH detection performance for 3GPP LTE TDD / FDD dual mode downlink receiver in various channel environments.

• Korean Journal of Environmental Agriculture
• /
• v.42 no.4
• /
• pp.259-268
• /
• 2023

Rhodococcus sp. 3-2 strain has been reported to degrade benzimidazole-based pesticides, such as benomyl and carbendazim. Therefore, this study aimed to optimize culture medium composition and culture conditions to achieve cost-effective and efficient large-scale production of the Rhodococcus sp. 3-2 strain. The study identified that the optimal media composition for mass culture comprised 0.5% glucose, 0.5% yeast extract, 0.15% NaCl, 0.5% K₂HPO₄, 0.5% sodium succinate, and 0.1% MgSO₄. Additionally, a microbial agent was developed using a 1.5-ton fermenter, with skim milk (20%), monosodium glutamate (15%), and vitamin C (2%) as key components. The storage stability of the microbial agent has been confirmed, with advantages of low temperature conservation, which helps to sustain efficacy for at least six months. We also assessed the benomyl degradation activity of the microbial agent within field soil. The results revealed an over 90% degradation rate when the concentration of viable cells exceeded 2.65 × 10⁶ CFU/g after a minimum of five weeks had elapsed. Based on these findings, Rhodococcus sp. 3-2 strain can be considered a cost-effective microbial agent with diverse agricultural applications.

• Microbiology and Biotechnology Letters
• /
• v.37 no.4
• /
• pp.399-404
• /
• 2009

This paper described the formulation of functional cosmetics and evaluation of anti-wrinkle efficacy in clinical test. Cosmetics were formulated with highly purified $\beta$-carotene obtained from the culture broth of recombinant E.coli cells. Edible oil for solubilizing $\beta$-carotene, vitamine E for long-term storage, detergent/stabilizer (2.0%) for the complete formation of oil/water emulsion, dimethicone (0.35%) for good skin care, and sorbitol for skin moisturizer were also added as ingredients. Physical or chemical degradation of formulated products stored at $0^{\circ}C$, $25^{\circ}C$, or $40^{\circ}C$ was not observed for 60-day testing period. In clinical test, 68% of applicants observed wrinkle decrease after 8-week treatment. This result indicates that newly formulated cosmetics have strong potential for improving wrinkle skin care.

• Journal of Acupuncture Research
• /
• v.32 no.3
• /
• pp.69-81
• /
• 2015

Purpose : The first purpose of this study is to find out whether the water extract of Rehmanniae Radix Preparat(RRP), Cuscutae Semen(CS) and their combination(Ssangbohwan, SBH) have the effect of suppressing Receptor activator of nuclear factor kappa-B ligand(RANKL)-induced osteoclast differentiation. The second purpose of this study is to find out whether the water extract of RRP, CS and SBH have the effect of inhibiting osteoporosis in an osteoporosis model induced by lipopolysaccharide(LPS). Methods : After promoting differentiation of osteoclasts by treating the RANKL, we observed the effect by the administration of RRP, CS and SBH. In addition, by means of Reverse transcription polymerase chain reaction(RT-PCR), we assayed mRNA expression levels of NFATc1, c-Fos, TRAP and GAPDHS(Glyceraldehyde-3-phosphate dehydrogenase, spermatogeni) from bone marrow macrophages(BMMs). Similarly, the protein expression levels of NFATc1 (Nuclear factor of activated T-cells, cytoplasmic1), C-Fos, MAPKs(Mitogen-activated protein kinases) and ${\beta}$-actin in cell lysates were analyzed by means of Western Blotting. Finally, we determined the anti-osteoporotic effects of RRP, CS and SBH, through the use of Lipopolysaccharide-induced bone-loss mouse. Results : RRP, CS and SBH showed remarkable inhibitive effect on RANKL-treated osteoclast differentiation without cytotoxicity. SBH inhibited the phosphorylation of p38, Jun N-terminal kinases(JNK), and I-${\kappa}B$ and down-regulated the induction of c-Fos and NFATc1 by RANKL. RRP, CS suppressed degradation of I-${\kappa}B$, but it did not affect c-Fos and NFATc1 by RANKL. Lastly, in vivo data showed that RRP and SBH prevented bone erosion by LPS treatment. Conclusions : These results demonstrate SBH can be effective remedy for bone-loss diseases such as osteoporosis.

• Applied Biological Chemistry
• /
• v.39 no.5
• /
• pp.349-354
• /
• 1996

The Polyvinyl alcohol(PVA) oxidase involved in PVA degradation by microorganism has been purified to homogeneity from culture broth of Xanthomonas campestris J2Y grown in a minimal medium containing PVA as a sole carbon source. The enzyme was purified by DEAE-cellulose chromatograpy and Sephadex G-150 gel filtration. The purified PVA oxidase was electrophoretically homogeneous both in the absence and presence of SDS. The molecular weight of the enzyme was estimated to be about 55,000 daltons by SDS-polyacrylamide gel electrophoresis and Sephadex G-150 gel filtration. The native enzyme existed as a monomer. The optimal pH and temperature was shown to be pH 7 and $37^{\circ}C$ respectively. The activity of enzyme was stable below $55^{\circ}C$ and between pH range of $5{\sim}11$. The enzyme activity was significantly inhibited by metal compounds such as $Ag^{2+},\;Hg^{2+}$. While, metal ions such as $Mn^{2+},\;and\;Cu^{2+}$ stimulated the reaction. Km value of the enzyme for PVA was $7.04{\times}10^{-2}mmol/{\ell}$.

• Food Science and Preservation
• /
• v.18 no.5
• /
• pp.795-802
• /
• 2011

To determine the deacidification factor during carbonic maceration (CM), different temperature conditions were studied. The pH was higher in CM-$35^{\circ}C$ and CM-$25^{\circ}C$ and was lower in CM-$45^{\circ}C$. The total acid was inversely related to the pH. The malic-acid level decreased much more in CM-$35^{\circ}C$ than in CM-$45^{\circ}C$ while the lactic-acid level increased much more in CM-$35^{\circ}C$. The activity of the NADP-malic enzyme, which catalyzes the oxidative decarboxylation of L-malate into pyruvate, $CO_2$, and NADPH, was higher in CM-$25^{\circ}C$ and CM-$35^{\circ}C$ while CM-$45^{\circ}C$ showed no NADP-malic enzyme activity. The malic-dehydrogenase (MDH) activity was higher in CM-$25^{\circ}C$ and CM-$35^{\circ}C$ while CM-$45^{\circ}C$ showed no MDH activity. The oxalacetate decarboxylase activity was similar to the NADP-malic-enzyme and MDH activities. Pyruvate decarboxylase activity was shown in all the CM treatments. The L-lactic dehydrogenase (LDH) activity was not explored in the fermentation of pyruvate to lactate via LDH in the grapes during CM. In this study, it was confirmed that carbonic maceration reduced the malic acid during fermentation and was affected by the temperature. Moreover, it was assumed that the deacidification during the carbonic maceration of the grapes was probably correlated with the degradation enzyme activity of malic acid.

• Journal of Microbiology
• /
• v.45 no.6
• /
• pp.485-491
• /
• 2007

The effects of biological pretreatment on the Japanese red pine Pinus densiflora, was evaluated after exposure to three white rot fungi Ceriporia lacerata, Stereum hirsutum, and Polyporus brumalis. Change in chemical composition, structural modification, and their susceptibility to enzymatic saccharification in the degraded wood were analyzed. Of the three white rot fungi tested, S. hirsutum selectively degraded the lignin of this sortwood rather than the holocellulose component. After eight weeks of pretreatment with S. hirsutum, total weight loss was 10.7%, while lignin loss was the highest at 14.52% among the tested samples. However, holocellulose loss was lower at 7.81 % compared to those of C. lacerata and P. brumalis. Extracelluar enzymes from S. hirsutum showed higher activity of ligninase and lower activity of cellulase than those from other white rot fungi. Thus, total weight loss and changes in chemical composition of the Japanese red pine was well correlated with the enzyme activities related with lignin- and cellulose degradation in these fungi. Based on the data obtained from analysis of physical characterization of degraded wood by X-ray Diffractometry (XRD) and pore size distribution, S. hirsutum was considered as an effective potential fungus for biological pretreatment. In particular, the increase of available pore size of over 120 nm in pretreated wood powder with S. hirsutum made enzymes accessible for further enzymatic saccharification. When Japanese red pine chips treated with S. hirsutum were enzymatically saccharified using commercial enzymes (Cellulclast 1.5 L and Novozyme 188), sugar yield was greatly increased (21.01 %) compared to non-pre treated control samples, indicating that white rot fungus S. hirsutum provides an effective process in increasing sugar yield from woody biomass.

• Journal of Physiology & Pathology in Korean Medicine
• /
• v.23 no.1
• /
• pp.104-112
• /
• 2009

The purpose of this study was to investigate the anti-inflammatory effects of extract from GuBoEum(GBE) on the peritoneal macrophage. To evaluate anti-inflammatory effects of GBE. I measured cytokines (interleukin-6; IL-6, interleukin-12; IL-12, tumor necrosis factor-$\alpha$; TNF-$\alpha$) and nitric oxide (NO) production in lipopolysacchride (LPS)-induced macrophages. Furthermore, I examined molecular mechanism using western blot and also LPS-induced endotoxin shock. Extract from GBE does not have any cytotoxic effect in the peritoneal macrophages. Extract from GBE reduced LPS-induced IL-6, TNF-$\alpha$, IL-12 and NO production in peritoneal macrophages. GBE inhibited the activation of extracelluar signal-regulated kinase (ERK), C-Jun $NH_2$-terminal kinase (JNK) but not of p38, degradation of $I{\kappa}B-{\alpha}$ in the LPS-stimulated peritoneal macrophages. GBE inhibited the production of TNF-$\alpha$, IL-6 and IL-12 in serum after LPS injection. These results suggest that GBE may inhibit the production of TNF-$\alpha$, IL-6, and IL-12 through inhibition of ERK and JNK activation, and that GBE may be beneficial oriental medicine for inflammatory diseases.

• Journal of Korean Society of Water and Wastewater
• /
• v.23 no.6
• /
• pp.743-752
• /
• 2009

One of the major problems associated with operation of domestic sewer lines involves hydraulic problems such as insufficient conveyance capacity, exceeding maximum velocity, and deficiency of minimum velocity. It has also been pointed out that influent concentration lower than design concentration of pollutants, which is mainly caused by unidentified inflow and infiltration, degrades the operational efficiency of many sewage treatment plants (STPs). A computer-added analysis method supporting a coupled simulation of sewage quality and quantity is essentially required to evaluate the status of existing STPs and to improve their efficiency by a proper sewer rehabilitation work. In this study, dynamic water quality simulations were conducted using MOUSE TRAP to investigate the principal parameters that governs the changes of BOD, ${NH_4}^+$, and ${PO_4}^{3-}$3- concentrations within the sewer networks based on data acquired through on-site and laboratory measurements. The BOD, ${NH_4}^+$ and ${PO_4}^{3-}$3- concentrations estimated by MOUSE TRAP was lower than theoretical pollution loads because of sedimentation and decomposition in the sewer. The results revealed that sedimentation is a most important factor than other biological reactions in decreasing pollutant load in the sewers of C-city. The sensitivity analysis of parameters pertaining to water quality changes indicated that the effect of the BOD decay rate, the initial DO concentration, the half-saturation coefficient of dissolved BOD, and the initial sediment depth is marginal. However, the influence of settling rate and temperature is relatively high because sedimentation and precipitation, rather than biological degradation, are dominant processes that affect water quality in the study sewer systems.

• The Journal of Korean Institute of Communications and Information Sciences
• /
• v.32 no.9C
• /
• pp.801-809
• /
• 2007

LDPC Low Density Parity Check) code, which is an error correcting code determined to be applied to the 4th generation mobile communication systems, requires a heavy computational complexity due to iterative decodings to achieve a high BER performance. This paper proposes an algorithm to reduce the number of decoding iterations to increase performance of the decoder in decoding latency and power consumption. Measuring changes between the current decoded LLR values and previous ones, the proposed algorithm predicts directions of the value changes. Based on the prediction, the algorithm inverts the sign bits of the LLR values to speed up convergence, which means parity check equation is satisfied. Simulation results show that the number of iterations has been reduced by about 33% without BER performance degradation in the proposed decoder, and the power consumption has also been decreased in proportional to the amount of the reduced decoding iterations.