• Biomolecules & Therapeutics
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• v.25 no.4
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• pp.374-382
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• 2017

Autism spectrum disorder (ASD) remains unexplained and untreated despite the high attention of research in recent years. Aside from its various characteristics is the baffling male preponderance over the female population. Using a validated animal model of ASD which is the telomerase reverse transcriptase overexpressing mice (TERT-tg), we conducted ASD-related behavioral assessments and protein expression experiments to mark the difference between male and females of this animal model. After statistically analyzing the results, we found significant effects of TERT overexpression in sociability, social novelty preference, anxiety, nest building, and electroseizure threshold in the males but not their female littermates. Along these differences are the male-specific increased expressions of postsynaptic proteins which are the NMDA and AMPA receptors in the prefrontal cortex. The vGluT1 presynaptic proteins, but not GAD, were upregulated in both sexes of TERT-tg mice, although it is more significantly pronounced in the male group. Here, we confirmed that the behavioral effect of TERT overexpression in mice was male-specific, suggesting that the aberration of this gene and its downstream pathways preferentially affect the functional development of the male brain, consistent with the male preponderance in ASD.

• Journal of Environmental Policy
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• v.11 no.3
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• pp.149-170
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• 2012

The United Nations Climate Change Conference, Durban 2011, ended on December 12, 2011, 36 hours over its schedule, delivering the Durban Package, which consisted of, inter alia, the extension of the period for Kyoto Protocol term and the launch of Ad-hoc working Group on the Durban Platform for Enhanced Action. Despite the positive progress made in Durban, the future of post-2012 climate regime still seems cloudy. Before the Durban conference, some of Annex I countries with emissions reduction commitment under the Kyoto Protocol's first commitment period openly declared their intention not to participate in the second one, reducing the effectiveness of Durban agreement. Parties to the conference have a long list of difficult issues disturbing the materialization of the new legal agreement in 2020 such as level of mitigation targets of individual countries and legal nature of their commitment. Given this uncertainty, the Korean government should reinforce its domestic climate policies rather than settling in the fact that it remains as a non-Annex I county party under the Durban Agreement due to the extension of the Kyoto Protocol period. Domestically, it needs to continue to raise the public awareness for rigorous climate policies to transit its economy to low carbon pathway which reduces the country's dependency on fossil fuel in the long term. It is also important to implement cost effective climate policies to cope with domestic resistance and international competitiveness. Internationally, its priority would be working for trust-building in the on-going negotiation meetings to encourage meaningful participation of all parties.

• Journal of the Korean Institute of Traditional Landscape Architecture
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• v.32 no.4
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• pp.120-131
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• 2014

Sajikdan(a sort of national shrine in Korea) built at the time of foundation of Joseon was entrenched into Sajik Park going through Japanese colonial era and recently the efforts to restore it is in progress. The details of change in Sajikdan in terms of diachronic analysis are as follows: Firstly, the first period refers to one prior to Japanese colonial era from the first king (also named as "Taejo" in Korean) of the Joseon Dynasty, during which it secured and strengthened the presence as a place for performing important national rites in a nation. It was built on the foot of Inwangsan Mt. at the time of the first king in Joseon Dynasty at first, was destroyed fully by fire during a Japanese Invasion period to Korea(1592-98) and afterward its ancestral ritual facilities were completed under the regime of Youngjo. However, as Japanese intervention coming to the fore, its place was destroyed and then ancestral rites were also abolished in 1908. Secondly, next period falls on 1910 to 1944 when it was transformed and entrenched into a park by the Japanese Empire. While facilities related to a park and an heterogeneous building around the part of boundary were set up, the area of altar, a ritual house and d door of Sajikdan were also designated as historical remains and treasures. Thirdly, this period refers to one from Korea's liberation year from Japanese colony(1945) to the year of 1984 when it had a mixed placeness with the statues, monuments and buildings with heterogeneous nature built. Furthermore, a door of Sajikdan was removed and reconstructed over twice due to opening of Sajik Tunnel. Fourthly, a final period falls on 1985 to the present when efforts are in progress to restore the historicity and symbolism of Sajikdan. A plan for restoration is promoted but now is a difficult time suffering from troubles caused by residents' resistance. Scrutinized historical researches through excavation investigation and residents' understanding are required altogether for restoration of Sajikdan.

• Journal of the Korean Institute of Traditional Landscape Architecture
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• v.31 no.2
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• pp.58-69
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• 2013

This research try to review about individuals' living culture place by record to before process of transition and modify of Bugundang village's forest in Itaewon. A result is as follows. First, Itaewon Bugundang is located in highest site of center building of twon forest, it has been preserve by double fence and taboo subject. Physical element of village forest is a factor which give sanctity of Buhundang. Second, it is connecting Namsan and Yongsan Family Park as green space. Also Itaewon Bugundang isolated from the current residential area. but in the past, the main beliefs and rituals of its area are responsible for a diverse community where public service was strong. Itaewon Bugundang have played a role presenting a local taboos and social norms. Therefore, these elements of the local community have the traditional cultural values. Third, Zelkova and Kalopanax pictus need to be preserved the value by the Seoul Metropolitan Government. Fourth, components of Bugundang are built by Hwajucheong, Dangjigi house, seonangdan, monument, fence, masonry and various trees. And the function and role of each of these elements remains as traditional culture. And the structural features of historic architectural properties has the value as a registered cultural properties. Fifth, due to these features, the traditional landscape of Itaewon bugundang play a role succeeding disappearing traditional culture and is worth as a potentially valuable landscape elements. This study has significance to the excavation community tradition disappearing landscape and excavation of candidate new tradition.

• Science of Emotion and Sensibility
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• v.18 no.2
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• pp.75-84
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• 2015

Although various methods have been proposed and utilized for video reality improvement, use of olfaction still remains at a rudimentary stage. Previous research reported reality improvement effect of some scents when a video displayed specific objects whose odors matched to the scents provided. In addition, another study showed that provision of scents that correspond to the prevailing color of a video improves sense of immersion. However, the above studies have clear limitations because not all videos have specific odor or obvious color. Assuming, in this study, that sensibility-based scent provision in the absence of main odor or color will increase sense of reality, the present study aimed at building adjective profiles of various scents that convey different sensibilities. To this end, in Experiments 1 and 2, we collected a set of adjectives appropriate for description of scents, and in Experiment 3, we built profiles of 16 scents using 30 adjectives. In addition, we grouped scents of similar sensibilities using cluster analysis. These results could be used not only for video reality improvement but also for the purposes of emphasizing product concepts or store positioning, etc.

• Convergence Security Journal
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• v.16 no.4
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• pp.17-24
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• 2016

Many companies and organizations are building a mobile office environment using the LTE network, the national disaster network and Air Force LTE network are built for public safety and national defense. However the recent threats on information security have been evolving from information leakage to DDoS attacks to neutralize the service. Especially, the type of device such as Smart phones, smart pad, tablet PC, and the numbers are growing exponentially and As performance of mobile device and speed of line develop rapidly, DDoS attacks in the mobile environment is becoming a threat. So far, universal countermeasure to DDoS attacks has been interception the network and server step, Yet problem regarding DDoS attack traffic on mobile network and expenditure of network resources still remains. Therefore, this paper analyzes the traffic type distributed in the private mobile network such as the National Disaster Network, and Air Force LTE network in order to preemptively detect DDoS attacks on terminal step. However, as direct analysis on traffic distributed in the National Disaster Network, and Air Force LTE network is restricted, transmission traffics in Minecraft and uploading video file upload which exhibit similar traffic information are analyzed in time series, thereby verifing its effectiveness through establishment of DDoS attacks standard in mobile network and application that detects and protects DDoS attacks

• Journal of the Korean Institute of Landscape Architecture
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• v.45 no.1
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• pp.63-72
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• 2017

Gardening activities, plant raising, and general flowerbeds the public makes today can be found in the original form of cottage gardens in the United Kingdom. A cottage garden is a popular garden style of modern Britain, implying unique Englishness including ethnic sense and vernacular. In addition, the purpose of this study is to consider the modern movement in the United Kingdom in the past 200 years and read Englishness of cottage gardens through style differentiation and background of occurrence of cottage gardens appearing in this process. Therefore, this study is summarized as follows. First, a view of nature of the Englishman loving freedom and landscape acts as a key part of patriotism and is connected to the preservation of idyllic England. For this ideal of the Englishman of the country, idyllic British characteristics are found in various literatures and artistic fruits; cottage gardens, that is a form of new garden, were made with invigoration of supply and collection of plants. Second, an early form of cottage gardens was the domestic garden, in which there is a vegetable garden by middle-class move to a suburb according to urbanization, but evolved into a form of garden having both artistry and regionality, vernacular, and ecological characteristics with various situations of modern society(handicraft promotion movement, preservation of remains, and ancient building restoration movement). Wild gardens occurring in this process are a type of garden realizing wild fields and forests in the United Kingdom;they have made a big impact on many garden designers up to now. Cottage gardens, reflecting a variety of Englishness, is a subject of city planning and flower shows and is a culture symbolizing the United Kingdom.

• Journal of KIISE:Software and Applications
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• v.34 no.7
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• pp.635-645
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• 2007

Component technology has been widely accepted as an effective way for building software systems with reusable components, and Microsoft (MS) .NET is one of the recent representative component technologies. Model Driven Architecture (MDA) is a new development paradigm which generates software by transforming design models automatically and incrementally. Transformation of structural models in MDA has been successfully applied. However, transformation of dynamic models and pervasive services, such as transaction service, security service, synchronization service and object pooling are largely remains as an area for further research. The recent enterprise system has multi tier distributed architecture, and the functionality of early mentioned pervasive services is essential for this architecture. .NET platform can implement Component Object Model+ (COM+) component for supporting pervasive services by specify Attribute code. In this paper, we specify the functionalities of the COM+ component offering pervasive services, and then those functionalities are defined by UML profile. By using the profile, the Platform Specific Model (PSM) for .NET/C# is specified, and .NET components are automatically generated through our tool. The development productivity, extensibility, portability, and maintenance of software can be dramatically improved by using of the proposed methods.

• Journal of Distribution Research
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• v.15 no.4
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• pp.21-60
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• 2010

In recent retail environments, multichannel customer management increasingly has been considered a key element of successful CRM. Although customer's multichannel usage is believed to be potential cause of customer loyalty, the theoretical explanation about this causal relationship still remains unexamined and unanswered. In this paper, the authors present a systematic framework to test the postulated "multichannel usage-shopping experience-customer satisfaction" chain. To this end, we examine that the two core components of shopping experience(convenience and enjoyment) is a mediator of the direct causality of multichannel usage(based on both information search and product purchase stage) on customer satisfaction. Moreover, the authors examine that two types of customer-firm relationship characteristics(relationship age and purchase frequency) is a moderator of the multichannel usage-shopping experience relationship. Using integrating data with survey and customer database of multichannel retail company, the authors empirically test and substantiate shopping experience's mediating role in the multichannel usage-customer satisfaction relationship and customer-firm relationship characteristics' moderating role in the multichannel usage-customer experience relationship. These results suggest that multichannel retailers should deliver favorable shopping experience for building customer satisfaction and differentiate shopping experience according to customer-firm relationship characteristics.

• Korean Journal of Heritage: History & Science
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• v.52 no.3
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• pp.94-111
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• 2019

This study aims to examine the evolutionary process of the protection-management system for historic monuments and their surroundings in France over one-hundred years. Because France and Korea shared policies and institutions regarding the management of historical monuments (cultural property) along with their surroundings, it is necessary to explore the French experience from a comparative perspective. In France, historical monuments began to be recognized as national heritage according to "the 1913 law" which has continued to evolve for more than one hundred years. In the beginning, a historical monument was preserved as a single building unit; however, since 1943, a new policy has been implemented to preserve sets of historical monuments along with their perimeters of protection zones. Moreover, since 1980, in the context of decentralization, local authorities have been given more roles and autonomy concerning the management of historic monuments and their surroundings. Local authorities have played a key role in the protection-management of historic monuments and their surroundings, and have become more active in the conservation of their architectural heritage, including historic monuments. The central government, however, remains as the headquarters whose rigorous policies provide a solid foundation for the decentralized management system of architectural and cultural heritage, including historic monuments. The final goal in the evolutionary process, then, targets the effective and harmonious integration of the protection-management system for historic monuments and their surroundings into urban and regional planning.