• Title/Summary/Keyword: brain text

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Analysis of hemodynamics in cerebral artery related to moyamoya disease (모야모야병과 연관된 뇌동맥에서의 혈류역학 분석)

  • Lee, Seung-Cheol;Lim, Ki-Moo;Shim, Eun-Bo
    • Proceedings of the KSME Conference
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    • 2008.11a
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    • pp.1647-1650
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    • 2008
  • The moyamoya disease is a type of cerebrovascular disease which produces thin abnormal blood vessels like haze in the brain base because the end of internal carotid artery which supplies about 80% of blood is blocked. Regarding this moyamoya disease, the shearing stress and thrombus generation are mentioned as its main causes. This study three-dimensionally implemented the ICA, ACA, and MCA parts of the cerebrovascular configuration related to the moyamoya disease, and analyzed the hydrodynamic phenomenon with the commercial program ADINA. In particular, the correlations between shearing stress and speed distribution according to the branch angle of ACA and MCA. A numerical analysis found that the greater the branch angle of ACA and MCA, the lower the shearing stress and the greater the stationary area of the flow.. Put Abstract text here.

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Visualizing the phenotype diversity: a case study of Alexander disease

  • Dohi, Eisuke;Bangash, Ali Haider
    • Genomics & Informatics
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    • v.19 no.3
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    • pp.28.1-28.4
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    • 2021
  • Since only a small number of patients have a rare disease, it is difficult to identify all of the features of these diseases. This is especially true for patients uncommonly presenting with rare diseases. It can also be difficult for the patient, their families, and even clinicians to know which one of a number of disease phenotypes the patient is exhibiting. To address this issue, during Biomedical Linked Annotation Hackathon 7 (BLAH7), we tried to extract Alexander disease patient data in Portable Document Format. We then visualized the phenotypic diversity of those Alexander disease patients with uncommon presentations. This led to us identifying several issues that we need to overcome in our future work.

Design and Development of Middleware for Clinical Trial System based on Brain MR Image (뇌 MR 영상기반 임상연구 시스템을 위한 미들웨어 설계 및 개발)

  • Jeon, Woong-Gi;Park, Kyoung-Jong;Lee, Young-Seung;Choi, Hyun-Ju;Jeong, Sang-Wook;Kim, Dong-Eog;Choi, Heung-Kook
    • Journal of Korea Multimedia Society
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    • v.15 no.6
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    • pp.805-813
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    • 2012
  • In this paper, we have designed and developed a middleware for an effectively approaching database to the existed brain disease clinical research system. The brain disease clinical research system was consisted of two parts i.e., a register and an analyzer. Since the register collects the registration data the analyzer yields a statistical data which based on the diverse variables. The middleware has designed to database management and a large data query processing of clients. By separating the function of each feature as a module, the module which was weakened connectivity between functionalities has been implemented the re-use module. And image data module used a new compression method from image to text for an effective management and storage in database. We tested the middleware system using 700 actual clinical medical data. As a result, the total data transmission time was improved maximum 115 times faster than the existing one. Through the improved module structures, it is possible to provide a robust and reliable system operation and enhanced security functionality. In the future, these middleware importances should be increased to the large medical database constructions.

A Study on the Editions of Myeongri Original Text 'Jeokcheonsu' (명리원전 『적천수(滴天髓)』의 판본 연구)

  • Na, Hyeok-Jin;Kim, Ki-Seung
    • Industry Promotion Research
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    • v.6 no.3
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    • pp.49-57
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    • 2021
  • The purpose of this paper is to examine the editions of 'Jeokcheonsu', the best Myoungri Classic in name and reality, that was featuring dozens of annotations and interpretations from the Qing Dynasty to the Republic of China, and modern times. The original author of 'Jeokcheonsu' was Gyeongdo of the Song Dynasty, firstly annotated by Yugi of the late Yuan Dynasty to Early Ming Dynasty, and Im Cheolcho of the Qing Dynasty annotated again. However, several observations in the original text suggest that the author's period of writing is postulated since the middle of the Ming Dynasty, and if the book is not likely to belong to the Song Dynasty, the author is also unlikely to be Gyeongdo of the Song Dynasty. Besides, if you look at the statements of Jin Soam and Jeong Jiwoon, who published the early editions of 'Jeokcheonsu', there are many negative opinions about the usual author recognition. In this study, we conducted a comparative analysis of the four existing editions of 'Jeokcheonsu', 'Jeokcheonsu-Jibyo' edited and published by Jin Soam, 'Myeongri Suji Jeokcheonsu' revised by Jeong Jiwoon, 'Jeokcheonsu-Cheonmi' annotated by Im Cheolcho, and 'Jeokcheonsu-Jingui' edited and published by Seo Rako. It is hoped that this study will help us understand 'Jeokcheonsu' more deeply and help us with related research, such as comparative studies of annotations in the future.

Efficient way to input text through eye gazing method. (시선입력 인터페이스 시스템의 효율적 문자입력 방법)

  • Kwon, O-Jae
    • Archives of design research
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    • v.20 no.3 s.71
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    • pp.289-298
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    • 2007
  • The EGI system is a new communication method in limelight for helping disabled users to input and handle information on the computer more easily. However, due to the EGI system's "JEM(Jittery Eye Movements)" generation, it actually increases heavy psychological and physiological stresses for the user to input or perceive the target information on a machine. This study illustrates how to resolve this "JEM" issue and suggests a method that is easy and simple to be controled by anyone. A demo tool was built and tested to find and prove the reasons for "JEM" This test shows that that the case with snap up is less stressful than without to input text as a final result of the test evaluation in both psychological snap up and physiological brain wave test. Postnatal or naturally acquired, it is found that the disabled can have opportunities for smoother communication, and a possible efficient system development for better communication.

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A Study on the Translation Criteria of ENFU SIN, DAL, AH on the Translation Methodology of Myeongri Classical (명리고전(命理古典) 번역(飜譯) 방법론(方法論)에 관한 엄복(嚴腹)의 신(信)·달(達)·아(雅)의 번역 기준 연구(硏究))

  • Kim, Hyun-Deok;Kim, Ki-Seung
    • Industry Promotion Research
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    • v.5 no.1
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    • pp.73-87
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    • 2020
  • The purpose of this paper was to find examples of a group of interpretations while biased toward the translation of the manuscripts of Myeongnology, and to apply the criteria of the translation of the manuscripts of Myeongnology in accordance with the criteria of SIN(信), DAL(達), and AH(雅) of EOM-BOK. Since the original author's intention should be faithfully reflected, the translation of the original book should be applied to the interpretation required at that time based on the translation corresponding to SIN(信), the translation corresponding to DAL(達) and the AH(雅) translation corresponding to the elegant interpretation. Translation is the most important purpose of implementing equivalence in the intentions of the original author, so the equivalence of the Source language and the Taget language should be observed even in the differences of expression. Up until now, the question of the translation of the nouns has mainly focused on the translation of the stylistic system by focusing on trying to overcome the structural differences of the language. Translation now requires the implementation of semantic equivalence as well as primarily a stylistic approach. This researcher wanted to open a new horizon for the study of classical literature in Myong-hak by presenting a standard for the translation of robes that achieve the intent and equivalence of the original author in the translation of the original text.

Effect of Banhahoobak-tang (Banxiahoupo-tang) Extract (BHTe) on Psychological Stress (반하후박탕(半夏厚朴湯)이 생쥐의 심리적 스트레스에 미치는 영향과 유전자 분석)

  • Choi, Geum-Ae;Cho, Su-In;Kim, Kyeong-Su;Choi, Chang-Won;Wei, Tung-Shuen;Yang, Seung-Joung;Park, Soo-Yeon;Kim, Kyeong-Ok
    • Journal of Oriental Neuropsychiatry
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    • v.26 no.2
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    • pp.117-130
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    • 2015
  • Objectives: Banhahoobak-tang has been used to treat plum-pit qi, chest and hypochondriac distension, moist or greasy tongue coat, and wiry slow or wiry slippery pulse. It might be used to control coughing and vomiting. We observed that Banhahoobak-tang extract (BHTe) had anti-psychological stress effect. The objective of this study was to determine the effect of BHTe on restoring the transcriptional regulation of genes related to psychological stress. Methods: After giving psychological stress to mice, BHTe was orally administered at 100 mg/kg/day for five days. After extracting whole brain tissue from the mice, the gene expression changes were determined by microarray. Transcription factor binding site (TFBS) analysis showed up- and down-regulated genes related to psychological stress were protected by BHTe and segregated according to the structure of TFBS. We performed text based Pubmed search to select significant target genes involved in psychological stress affected by BHTe. Results: 1. Serum corticosterone level was decreased in the BHTe administered group, although the psychological stress was increased. 2. The BHTe administered group had no significant change in noradrenaline content in brain tissue, but the psychological stress group had decreased level. 3. The BHTe administered group had increased time of staying at open-arm than the psychological stress group. 4. Microarray revealed that TANK and RARA genes were up-regulated genes while AES, CDC42, FOS, NCL, and PVR were down-regulated genes by psychological stress but restored by BHTe.