• 한국방사선학회논문지
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• 제5권5호
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• pp.237-244
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• 2011

일반적으로 저 에너지 방사선 조사로 검사하게 되는 치과 영역에서는 투과력이 약해 인체에 흡수되는 양이 많다. 치과 영역에서 방사선검사 시 부득이하게 방사선 노출을 받게 되는 방사선 작업종사자나 환자의 보호자가 위치와 거리에 따른 방사선 피폭 선량의 감소 방안을 알아보고자 한다. 진단용 발생장치인 GX-770, CRANEX TOME CEPH와 조사선량 측정기인 Ion chamber model 2026c, Reader기 20X6-1800을 사용하여 구강내 검사와 구강외 검사의 각각 검사실과 조정실에서의 관전압의 변화, 관전류와 조사시간의 변화, 조사방향의 변화에 따라 선량을 측정하였다. 그 결과 최고선량이 검사실 안에서는 평균 702.8 ${\mu}R$으로 측정 되었으며, 조정실 안에서 측정하였을 경우 20 ${\mu}R$이하의 낮은 선량을 보였으며, 120cm 거리에서 후방검사보다 측방검사가 낮은 선량으로 나타났다. 방사선검사시 위치와 거리에 따른 조사선량을 비교 분석하여, 적절한 거리 확보와 조사되는 중심방사선을 기준으로 측방($90{\sim}135^{\circ}$)에 위치함으로써 방사선 방어에 도움을 줄 것이며, 차폐문을 이용하여 방사선 피폭으로부터 감소 효과를 볼 수 있을 것이다.

• 한국학교보건학회지
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• 제11권2호
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• pp.203-215
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• 1998

The purpose of this study is to inquire into the degree of health promotion activity in university students, and to find out the relationship between self-efficiency and health promotion behavior, Thus, we can offer basic data for developing an educational method or program for health promotion. For this research, data was collected from university men and women through a questionnaire from February 18 to March 20, 1998. A measuring instrument was based on lating reviews of health promotion behavior in chronic disease protection, perceived self efficiency, demographic factors, biological factors, and circumstatial factors. The content validity of the instrument was authenticated by two professors of nursing, and reliability was confirmed by 'cronbach' (${\alpha}^{\prime}$ after mortifying content through a pre-test on 30 students. 475 persons were analyzed in terms of average, percentage, t-test, ANOVA, Pearson's Correlation Coefficient, and Multiple Stepwise Regression by 'SPSS-PC'. The analyzed data is as follows: 1. Higher self-efficiency, as a cognitive-perceptual factor, has a beneficial effect on health promotion behavior (r=.479, p=.000). The result of analyzing the differences among a low group, a middle group, a high group in terms of self-efficiency reveals that the relationship between self-efficiency and health promoting behavior is meaningful. 2. The degree of health promoting behavior is 3.26 out of 6. Other figuresrelating to health promoting behavior, are as follows. self-actualization area (4.62), interpersonal area (4.60), stress management area (4.01), nutrition area (3.68), responsibility of health area (3.11), liquid and cigaret area (2.85), and exercise area (2.33). 3. The degree of self-efficiency was 6.81 out of 10. Other figures relating to self-efficiency are as follows. interpersonal area (7.89), self-actualization area (7.84), liquid and cigarette area (7.72), exercise area (6.88), stress management area (6.84), responsibility of health area (6.35), and nutrition area (6.34). 4. The different lerels of health promoting behavior according to a subject's general factos are following: age (p=0.003), sex (p=0.000), health concern of parents (p= 0.000), taking health programs (p=0.007), case history of familes (p=0.048). Health promoting behavier is also positirely affeted by the following: higher age, social sciences focus, religion, living the relatives', and the higher health concerns of parents. 5. The difference of self-efficiency according to a subject's general factors is positirely affected by sex (p=.008), the health concerns of parents (p=.004), body indexes (p=.001), and the higher health concerns of parents. 6. As the result of analyzing major factors, the most powerful factor appears to be self-efficiency, 26.6% of health promoting behavior. Suggestions: 1. Results of this study point to self-efficiency as a major factor in the health promoting behavior of university students. It is crucial, therefore, to develop a health program to promote self-efficiency and to study how to promote prerention of certain diseases. 2. That health promoting behavior appears low in this study shows that health education should be taken into the university class, with a focus on the daily life of students as its goal.

• 한국화재소방학회논문지
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• 제33권6호
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• pp.35-42
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• 2019

본 논문은 피난기구의 사용시간 실험분석을 통한 안전체험교육 개선에 관한 방향을 알아보기 위해 진행되었다. 연구를 위해 피 실험자들을 체격과 체중이 비슷한 그룹으로 나누어 구성하였고, 4가지 피난기구를 직접 체험하게 함으로서 체험시간을 측정하여 분석하였다. 피난기구 설치에서부터 탈출까지의 전체시간 분석에서 완강기-경사식구조대-수직구조대-공기안전매트 순으로 탈출시간이 소요되었다. 피난기구의 탈출시간만 분석했을 경우에는 공기안전매트-경사식구조대-완강기-수직구조대 순으로 탈출시간이 분석되었다. 완강기의 1차 2차 실험에서 나타난 것처럼 1차 시간은 경험 후에 2차 시도에서 시간이 줄어들었다. 이처럼 체험을 통한 교육은 행동의 자신감 증가와 시간의 관리가 가능한 것으로 나타났다. 본 연구의 결론으로 안전교육의 목표는 인명과 재산피해의 최소화이고, 이를 위한 노력으로 많은 사람들에게 교육을 통해 최소화 하는 방법과 자신의 안전을 지키는 교육을 진행한다. 그러므로 더 많은 사람들에게 이러한 효과를 가져 오기 위해서는 체험교육을 통해 학습효과를 높이고, 자기안전을 지키게 하는 노력이 필요하다.

• 한국임상약학회지
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• 제21권3호
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• pp.256-269
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• 2011

Omega-3 fatty acids are a specific type of unsaturated fat that the body cannot manufacture on its own, so they must be obtained from food which is essential fatty acids (EFAs). Omega-3 fatty acids consist of three types which are a-Linolenic Acid (ALA), Eicosapentaenoic (ELA), and Docosahexaenoic Acid (DHA). Especially, EFAs help to prevent skin and hair drying, acne, eczema, prevention from allergies, brittle nails, rashes, and tiny lumps. The aim of this study is to investigate improvement and protection for hair damaged by chemical treatment with omega-3 formulated shampoo. We selected virgin hair sample and divided into two groups for bleaching once and three times and then damaged hair by changing the number of hair bleaching (twice with interval of 15 minutes). Each bleached hair was treated by five different kinds of shampoo (Control, Horse shampoo, DHA shampoo, EPA shampoo, Omega-3 shampoo mixture). Apart from this, EPA/DHA 2, 5, 8, 10 and 12% shampoo were prepared and treated to hair for comparing rate of progress in damaged hair. To quantify improved condition of damaged hair, we performed Scanning Electron Microscope (SEM) for ultrastructure of damaged hair fraction, measurement of thickness change and BCA Protein Assay for recovery rate of damaged hair. The moisture in hair was measured by Thermal analysis machine. In results, we observed the particle of hair surface damaged by bleaching treatment were well improved with treatment with EPA and DHA shampoo. Also, quantity of protein was lowered with higher concentration of EPA & DHA i.e., 8 and 12 % then compared with horse oil shampoo in three times treatment group. It shows that bleached hair have been recovered by treating rapidly and get protective coat. In conclusion, EPA and DHA shampoo improved damaged hair, especially with EPA / DHA 12% shampoo. Also, EPA shampoo could protect the damaged hair depending on increasing concentration of EPA. Therefore, we conclude omega-3 shampoo could make damaged hair protect and get healthy hair environment.

• 한국방사선학회논문지
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• 제9권4호
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• pp.257-261
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• 2015

라돈은 우라늄-238과 토륨-232가 방사성붕괴 과정을 거친 후 생성되며, 무색, 무취의 불활성 기체로서 지하 또는 밀폐된 공간에 축적된다. 우라늄-238과 토륨-232는 지각의 암석이나 토양 등에 포함 돼 있다. 건축자재는 암석이나 토양을 재료로하여 만들어 진다. 가스 형태의 라돈은 호흡기를 통해 폐로 유입되고 라돈의 딸핵종이 폐나 기관지에 침적 되어 폐암을 일으키는 원인이 된다. 본 연구는 광주광역시 광산구에 위치한 신축 아파트를 대상으로 창문을 닫고 열은 상태에서 라돈 측정기를 이용하여 측정하였다. 측정 결과로 보아 신축 아파트 실내 평균 라돈농도는 미국 일반인 공기 중 라돈가스 최대허용농도 기준치 4 pCi보다 이하의 값이 나타난다는 것을 볼 수 있다. 측정 결과로 볼 때 신축 아파트의 라돈농도로 인한 피폭은 크지 않을 것으로 예상한다. 그러나 라돈가스가 신체 내에 축적이 되면 폐와 같은 경우는 폐암과 같은 피폭에 의한 피해를 얻을 수 있으므로 방사선 방어적 측면에서 측정 결과와 같이 라돈 농도를 낮추기 위해 창문을 자주 열어 환기를 시켜 피폭을 줄이는 것이 필요하다고 생각 된다.

• 대한수의학회지
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• 제47권3호
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• pp.291-298
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• 2007

Olive flounder, Paralichthys olivaceus is one of the most important cultured fish in Korea, its farming has been negatively impacted by viral, bacterial and parasitic diseases. Streptococcal infection was considered as a serious problem because of significant economic losses in olive flounder farm industry. The development and evaluation of vaccine for protection against infection by this agent were required. We evaluated the safety and efficacy of ${\beta}$-hemolytic Streptococcus (S.) iniae vaccine on olive flounder Three hundreds of flounders (weight $119.8{\pm}20.7g$, body length $22.6{\pm}1.4cm$) were reared in 0.5 tons aquaria in land-marine tank system. Seawater was provided from the sea of Inchon in Korea, and water temperature was set to $22^{\circ}C$ and $25^{\circ}C$ in the vaccination and challenge test, respectively. We used the formalin-inactivated ${\beta}$-hemolytic S. iniae (F2K) vaccine (M VAC INIAE; Kyoritsu seiyaku, Japan) originated in Japan. The vaccine was intraperitoneally administered to fish. Both of vaccinated group and control group were challenged with intraperitoneally injection by virulent S. iniae SI-36 isolates with $1.0{\times}10^7CFU/fish$ at 3 weeks after vaccination. Difference on mortality of control and vaccinated group (90.0 and 15.0%, 76.5 and 8.0% respectively) at two trials were found significant (p<0.05), and relative percent survival were 83.4% and 89.5%, respectively. The dead fishes were showed dark pigmentation of skin, abdominal extension, hemorrhagic ascites, and liver necrosis, and isolated the S. iniae strain from ascites, liver and kidney. We confirmed the safety and efficacy of ${\beta}$-hemolytic S. iniae vaccine by determinations of the optimal management condition and artificial challenge test in olive flounder.

• 한국산학기술학회논문지
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• 제11권10호
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• pp.3820-3825
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• 2010

본 연구는 일회성 점증부하에 의한 혈액 세포내 항산화 효소 발현을 비만인과 정상인을 대상으로 운동의 효과에 대한 생화학 적응을 밝히는데 그 목적을 두고 시도되었다. 본 연구에 참가한 피험자는 본 연구의 목적을 충분히 이해하고 자발적인 참여를 원하는 비만인 8명과 정상인 8명의 총 16명이었다. 정상인 집단 8명은 특별한 대사성 질환이나 근골격계 질환이 없었으며, 비만여부의 판정기준은 체지방율 25% 이상으로 하였다. 피험자들의 혈액은 안정시, 운동직후, 그리고 회복기에 각각 자료처리 분석을 위해 집단 간 시기별 측정치의 차이분석을 위해 공변량분석을 실시하였다. 본 연구결과, 운동직후 정상인이 SOD 활성이 비만인 보다 통계적으로 높게 나타났다 (p<0.05). 일회성 운동이 비만인의 항산화 효소 활성보다 정상인의 항산화 효소 활성을 높게 한다는 결과는 운동직후 정상인의 ROS 생성이 활발해짐과 동시에 항산화 체제가 활성화되어 활성산소의 중화제 역할을 수행하는 것으로 사료된다.

• Nutrition Research and Practice
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• 제9권1호
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• pp.22-29
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• 2015

BACKGROUND/OBJECTIVES: Recently, anthocyanins have been reported to have various biological activities. Furthermore, anthocyanin-rich purple corn extract (PCE) ameliorated insulin resistance and reduced diabetes-associated mesanginal fibrosis and inflammation, suggesting that it may have benefits for the prevention of diabetes and diabetes complications. In this study, we determined the anthocyanins and non-anthocyanin component of PCE by HPLC-ESI-MS and investigated its anti-diabetic activity and mechanisms using C57BL/KsJ db/db mice. MATERIALS/METHODS: The db/db mice were divided into four groups: diabetic control group (DC), 10 or 50 mg/kg PCE (PCE 10 or PCE 50), or 10 mg/kg pinitol (pinitol 10) and treated with drugs once per day for 8 weeks. During the experiment, body weight and blood glucose levels were measured every week. At the end of treatment, we measured several diabetic parameters. RESULTS: Compared to the DC group, Fasting blood glucose levels were 68% lower in PCE 50 group and 51% lower in the pinitol 10 group. Furthermore, the PCE 50 group showed 2-fold increased C-peptide and adiponectin levels and 20% decreased HbA1c levels, than in the DC group. In pancreatic islets morphology, the PCE- or pinitol-treated mice showed significant prevention of pancreatic ${\beta}$-cell damage and higher insulin content. Microarray analyses results indicating that gene and protein expressions associated with glycolysis and fatty acid metabolism in liver and fat tissues. In addition, purple corn extract increased the phosphorylation of AMP-activated protein kinase (AMPK) and decreased phosphoenolpyruvate carboxykinase (PEPCK), glucose 6-phosphatase (G6pase) genes in liver, and also increased glucose transporter 4 (GLUT4) expressions in skeletal muscle. CONCLUSIONS: Our results suggested that PCE exerted anti-diabetic effects through protection of pancreatic ${\beta}$-cells, increase of insulin secretion and AMPK activation in the liver of C57BL/KsJ db/db mice.

• 대한방사선기술학회지:방사선기술과학
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• 제31권2호
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• pp.177-182
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• 2008

디지털 시스템이 가지는 장점인 영상판 검출기의 반응 범위(dynamic range)가 상당히 넓다는 것은 필름/증감지 시스템보다 더 높은 수준의 노광 관용도를 갖기에 재촬영이 줄어들고 영상관리에 효율적이지만, 조사조건의 설정범위가 상당히 넓어 필름/증감지 시스템의 엄격한 조사조건보다 더 많은 조사선량이 환자에게 노출 될 수도 있다. 본 연구는 디지털 시스템 하에서 일반촬영 시 방사선사 개인 별 조사선량에 대한 인식과 행위실태를 파악하여 환자피폭선량을 감소시킬 수 있는 방안을 마련하고, 방사선 선량관리의 중요성을 새로이 인식하고자 하였다. 디지털 시스템 하에서 근무 중인 방사선사의 조사조건 설정과 환자피폭선량 인지 실태를 파악해 본 결과 환자의 체형이나 상태, 촬영부위에 따라 최적의 조사선량을 적용하기 보다는 영상의 농도와 업무의 편의성에 따라 조사조건이 설정되고 있었다. 디지털 시스템이 도입되며 검출기의 반응 범위가 필름/스크린 시스템보다 넓어짐에 따라 조사조건 설정에 대해 관심이 소홀한 경향이 있었다. 따라서 디지털 방사선 시스템 하에서 환자 피폭선량의 감소를 위해 최적의 조사조건으로 영상을 얻어야 할 것이다. 또한 조사선량을 최소로 하고 환자 피폭선량을 줄이기 위해 업무 습관과 인식을 새로이 할 필요성이 있고, 지속적인 관심과 주기적인 교육 및 점검, 다양한 교육 기회제공 등이 필요하다고 본다.

• Journal of Microbiology and Biotechnology
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• 제29권12호
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• pp.1947-1956
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• 2019

The gut microbiome influences the health and well-being of dogs. However, little is known about the impact of breed on the fecal microbiome composition in dogs. Therefore, we aimed to investigate the differences in the fecal microbiome in three breeds of dog fed and housed under the same conditions, namely eight Maltese (8.0 ± 0.1 years), eight Miniature Schnauzer (8.0 ± 0.0 years), and nine Poodle dogs (8.0 ± 0.0 years). Fresh fecal samples were collected from the dogs and used to extract metagenomic DNA. The composition of the fecal microbiome was evaluated by 16S rRNA gene amplicon sequencing on the MiSeq platform. A total of 840,501 sequences were obtained from the 25 fecal samples and classified as Firmicutes (32.3-97.3% of the total sequences), Bacteroidetes (0.1-62.6%), Actinobacteria (0.2-14.7%), Fusobacteria (0.0-5.7%), and Proteobacteria (0.0-5.1%). The relative abundance of Firmicutes was significantly lower in the Maltese dog breed than that in the other two breeds, while that of Fusobacteria was significantly higher in the Maltese than in the Miniature Schnauzer breed. At the genus level, the relative abundance of Streptococcus, Fusobacterium, Turicibacter, Succinivibrio, and Anaerobiospirillum differed significantly among the three dog breeds. These genera had no correlation with age, diet, sex, body weight, vaccination history, or parasite protection history. Within a breed, some of these genera had a correlation with at least one blood chemistry value. This study indicates that the composition of the fecal microbiome in dogs is affected by breed.