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http://dx.doi.org/10.5762/KAIS.2010.11.10.3820

Effects of gradual loaded exercise on antioxidative enzymes response in normal and obese men  

Kim, Jin-Woo (Emergency Medical Technology, JuSung College)
Cho, Byung-Jun (Emergency Medical Technology, Kangwon National University)
Han, Gun-Soo (Department of Health Science, Kinesiology, Recreation and Dance, University of Arkansas)
Publication Information
Journal of the Korea Academia-Industrial cooperation Society / v.11, no.10, 2010 , pp. 3820-3825 More about this Journal
Abstract
The purpose of this study was to identify the effects of acute exercise on antioxidative enzymes in noramal and obese men. The written informed consent was obtained from 16 participants of eight normally healthy persons and eight obesity ones. The baseline level of obesity was determined at 25 % of the body fat. Any subjects had no experiences in participating in exercise and did not take vitamin or mineral supplement. Blood was sampled at five minutes before exercise, at exhaustion, and after 30 minutes of recovery. All statistical analyses and description methods were computed by SPSS window 14.0. Analysis of Covariance(ANCOVA) was performed to know the differences in values between pre- and post- exercise in each group. We found that after exhaustion, the normal group showed higher erythrocyte superoxide dismutase (SOD) activity compared to the obesity group. At exhaustion, the normal group had lower HSP activity compared to the obesity group. Based on the results, an acute exercise of normally healthy people induced an up-regulation of superoxide dismutase (SOD) activity. This plays an important role in the protection of extra-cellular fluid components against peroxide-mediated damage.
Keywords
Obesity; SOD; Antioxidative enzymes; Exercise;
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Times Cited By KSCI : 1  (Citation Analysis)
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1 L. L. Ji, "Exercise & oxidative stress: Role of the cellular antioxidant systems. In: Exercise & Sports Science Review", edited by Journal. Hollozsy. Baltimore, MD: Williams & Wilkins, 1995.
2 J. M. Gutteridge, J. Stocks, "Peroxidation of cell lipids", Medicine Laboratory Sciences, Vol. 33, pp. 281-285, 1986.
3 L. L. Ji, "Antioxidant enzyme response to exercise & aging", Medicine & Science in Sports & Exercise, Vol. 25, pp. 225-231, 1993.
4 R. R. Jenkins, "Free radical chemistry : Relationship to exercise". Sports Medicine. Vol. 5, pp. 156-170. 1988.   DOI
5 김성수, 신말순, 김영표, 천병옥, 최형규, "장기간의 지구성 운동이 쥐의 혈액 항산화 효소, GSH 및 지질과산화에 미치는 영향", 한국운동과학회 논문지, 제7권, pp. 185-194. 1998.
6 배철웅, "장기간 규칙적인 유산소성 달리기 운동이 항산화 효소 활성도와 지질 과산화물의 변화에 미치는 영향", 한국체육학회지 논문지, 제40권, 제4호, pp. 829-839, 2001.
7 오해근, 김기진, 조성봉, "비만인의 지속적 운동시 운동 강도에 따른 생리적 변인의 변화", 한국사회체육학회 논문지, 제15권, pp. 539-607, 2001.
8 신말순,"장기간의 지구성 운동이 혈액 항산화 효소, GSH 및 지질과 산화에 미치는 영향", 고려대학교 대학원 박사학위논문, 1998.
9 진영수,. "운동과 항산화제", 서울, 중앙병원, 1998
10 M. J. Higuchi, et al., "Superoxide dismutse & catalase in skeletal muscle: Adaptive response to exercise", Journal of Gerontology, Vol. 40, pp. 281-286, 1985.   DOI   ScienceOn
11 C. J. Dillard, et al., "Effect of dietary vitamin E on expiration of tentane & ethane by the rat", Lipids, Vol. 12, pp. 109-114, 1976.
12 H. K. Vincent, et al., "Obesity is associated with increased mycardial oxidative stress". International Journal of Obesity, Vol. 23, No. 1, pp. 67-74, 1999.   DOI
13 남상남, 김종혁, 지민철, "유산소 운동을 병행한 근 저항성 운동이 노인 여성의 혈중 MDA 및 SOD, GPx 활성에 미치는 영향", 한국콘텐츠학회 논문지, Vol. 9, No. 11, pp. 391-398, 2009.   과학기술학회마을   DOI
14 T, Wenz et al., "Endurance exercise is protective for mice with mitochondrial myopathy", Journal of Applied Physiology, Vol. 106, pp. 1712-1719, 2009.   DOI
15 신정희, 김현숙, 권년수, "단기간의 운동이 마우스대식세포의 Nitric Oxide 생성 및 조직의 반응성산소종과 항산화효소 활성에 미치는 영향", 한국운동영양학회 춘계학술대회, 1998.
16 H. M. Alessio, "Lipid peroxidation & scavenger enzymes during exercise : Adaptive response to training", Journal of Applied Physiology, Vol. 64, pp. 1333-1336, 1988.
17 R. R. Jenkins, "The role of superoxide dismutase & catalase in muscle fatigue. In : Biochemistry of Exercise Champaign", Human Kinetics, Ch. 13, pp. 467-471. 1983
18 R. Jenkins, A. Goldfarb, "Introduction : oxidant stress, aging, & exercise, Medicine Science Sports Exercise", Vol. 25, pp. 210-212, 1993.
19 A. Bast, et al., "Oxidants & antioxidants : State of the art". American Journal of Medicine, Vol. 30, pp. 91-100. 1991.
20 A. J. Rivett, "Preferential degradation of oxidatively modified form of glutathione synthetase by intracellular mammalian proteases", Journal of Biological Chemistry, Vol. 260, pp. 300-305. 1985.
21 A. Boyum, et al., "The effect of strenuous exercise, calorie deficiency & sleep deprivation on white blood cells, plasma immunoglobulins & cytokines", Scandinavica Journal of Immunology, 43, 228-235, 1996.   DOI
22 박명수, "트레드밀 운동강도와 시간이 쥐의 심장근과 골격근의 HSP 72발현에 미치는 영향". 단국대학교 대학원 박사학위논문, 2001.
23 M. H. Laughlin, "Skeletal muscle oxidative capacity, antioxidant enzymes & exercise training", Journal of Applied Physiology, Vol. 68, pp. 2337-2343, 1990
24 L. L. Ji, et al., "Glutathione & antioxidant enzymes in skeletal muscle : Effects of fiber type & exercise intensity", Journal of Applied Physiology, Vol. 73, pp. 1854-1859, 1992.
25 D. H. Choi, "Influence of Exercise on Hindlimb Suspension-induced Alteration in Stress Proteins. Unpublished Doctoral Dissertation", The University of Toledo, 1997.
26 최대혁, "일회성 운동 및 지구력 운동이 HSP70 생성과 함량에 미치는 영향". 한국운동과학회 논문지, 제8권, pp. 519-528, 1999.