손상 모발을 위한 EPA 함유 샴푸 개발

Development of Shampoo Formulated by EPA for the Damaged Hair

  • 이보름 (충북대학교 약학대학 임상약학실) ;
  • 이옥상 (충북대학교 약학대학 임상약학실) ;
  • 강태진 (삼육대학교 약학대학) ;
  • 임성실 (충북대학교 약학대학 임상약학실)
  • Lee, Bo-Reum (Clinical Pharmacy, College of Pharmacy, Chungbuk National University) ;
  • Lee, Ok-Sang (Clinical Pharmacy, College of Pharmacy, Chungbuk National University) ;
  • Kang, Tae-Jin (Department of Pharmacy, College of Pharmacy, Sahmyook University) ;
  • Lim, Sung-Cil (Clinical Pharmacy, College of Pharmacy, Chungbuk National University)
  • 투고 : 2011.07.11
  • 심사 : 2011.08.18
  • 발행 : 2011.09.30

초록

Omega-3 fatty acids are a specific type of unsaturated fat that the body cannot manufacture on its own, so they must be obtained from food which is essential fatty acids (EFAs). Omega-3 fatty acids consist of three types which are a-Linolenic Acid (ALA), Eicosapentaenoic (ELA), and Docosahexaenoic Acid (DHA). Especially, EFAs help to prevent skin and hair drying, acne, eczema, prevention from allergies, brittle nails, rashes, and tiny lumps. The aim of this study is to investigate improvement and protection for hair damaged by chemical treatment with omega-3 formulated shampoo. We selected virgin hair sample and divided into two groups for bleaching once and three times and then damaged hair by changing the number of hair bleaching (twice with interval of 15 minutes). Each bleached hair was treated by five different kinds of shampoo (Control, Horse shampoo, DHA shampoo, EPA shampoo, Omega-3 shampoo mixture). Apart from this, EPA/DHA 2, 5, 8, 10 and 12% shampoo were prepared and treated to hair for comparing rate of progress in damaged hair. To quantify improved condition of damaged hair, we performed Scanning Electron Microscope (SEM) for ultrastructure of damaged hair fraction, measurement of thickness change and BCA Protein Assay for recovery rate of damaged hair. The moisture in hair was measured by Thermal analysis machine. In results, we observed the particle of hair surface damaged by bleaching treatment were well improved with treatment with EPA and DHA shampoo. Also, quantity of protein was lowered with higher concentration of EPA & DHA i.e., 8 and 12 % then compared with horse oil shampoo in three times treatment group. It shows that bleached hair have been recovered by treating rapidly and get protective coat. In conclusion, EPA and DHA shampoo improved damaged hair, especially with EPA / DHA 12% shampoo. Also, EPA shampoo could protect the damaged hair depending on increasing concentration of EPA. Therefore, we conclude omega-3 shampoo could make damaged hair protect and get healthy hair environment.

키워드

참고문헌

  1. C.A. Patterson, Ph.D., P.Ag : The Pathfinders Reasearch & Management LTd. : Omega-3 Fatty Acids (marine-derived) : Health Canadian Ingredients, Agriculture and Agri-Food Canada. 2006.
  2. Andrew P. DeFilipps, MD, and Laurence S. Sperling, M.D, FACC, FACP Atlanta, GA. Understanding Omega- 3's, American Heart Journal. 2006; 151: 564-570. https://doi.org/10.1016/j.ahj.2005.03.051
  3. Seth D. Feuerstein, New Haven, Ann Coric, Madison, Louis C. Sanfilippo, Orange : Omega 3 Fatty Acid Formulation, No. 60/752,146 file, US2007/0141138 A1. 2005.
  4. A. L. Stoll, C.A. Locke, L.B. Marangell, W.E. Severus : "Omega-3 Fatty Acids and Bipolar Disorder: a Review", Prostaglandins, Leukotrienes and Essential Fatty Acids, 1999; 60(5&6);. 329-337. https://doi.org/10.1016/S0952-3278(99)80008-8
  5. 김덕록: 화장과 화장품, 답계, 119 ISSN 89-7574-086-293590. 2002
  6. So Youn Kim, Ju Seub Kim : "The Study on Hair According to Keratin Treatment Method", J. Beau. Tricho, 2008; 4(1): 63-71.
  7. Mi-Ryeong An : A Study on the Usability and Foaming Ability of Shampoo According to Additives: Focused on the Addition of Chitosan, Dept. of Beauty Industrial Management Graduate school of Business Administration Yong-in university. 2003.
  8. Song, Pal-Yong : Management of Hair Damage Rate and Mechanical Properties after Chemical Treatment, master of cosmetology, graduate school of engineering, Konkuk University. 2005.
  9. Yeon Jung : "Changes of Human Hairs According to Hair Bleaching and Coating Treatment", International Journal of Beauty Industry, 2007; 2(2): 91-96.
  10. Menendez, J. A., Lupu, R. and Colomer, R : Exogenous Supplementation with Omega-3 Polyunsaturated with Acid Docosahexaenoic Acid (DHA; 22:6n-3) Synergistically Enhances Taxane Cytotoxicity and Downregulates HER-2/ neu (cerbB-2) Oncogene Expression in Human Breast Cancer Cells, Eur. J. Cancer Prev, 2005; 14: 263. https://doi.org/10.1097/00008469-200506000-00011
  11. Jin hee Park, Jeung sook Choi : "The Study of Heat Treatment Effect Before Using Ample on the Permanent Waving in Heavy Damaged Coloring Hair", Journal of Korea Society Cosmetic, 2003; 9(3): 88-95.
  12. Alvaro L. Gomes and Sueli S. Aguiar, Silicones as Protective Agents in Thermal Treatment for Hair, Dow Corning Latin America, 1-4. 2001.
  13. 최미경, Poly unsaturated fatty acid (PUFA)인 오메가 3의 임상적 적용근거와 예. 2006.
  14. 한경희강영숙김세욱김춘득소영진윤수용장경옥정영태, 모발과학, 훈민사. p.14. 2002.
  15. Caryl J. Antalis, Laura J. Stevens, Mary Campbell, Robert Pazdro, Karen Ericson, John R. Burgess : Omega-3 Fatty Acid Status in Attention-deficit/hyperactivity Disorder, Prostaglandins, Leukotriens and Essential Fatty Acids, 2006; 75: 299-308. https://doi.org/10.1016/j.plefa.2006.07.004
  16. Darish Mozaffarian, Eric B. Rimm, Fish Intake, Contaminants, and Human Health: Evaluating the Risks and the Benefits, JAMA. 2006; 295(15): 1885-1989. https://doi.org/10.1001/jama.295.16.1885
  17. Du Seok Han, Hyoung Gyu Choi, Jeong Il Kang, Hwa Jung Choi, Seung Hwa Baek : Growth Inhibitory Effects of Omega-3 Unsaturated Fatty Acid Cancer Cell Lines, Yankhak Haeji. 2008: 52(4); 264-273.
  18. Gary M. Davenport, PhD, Gregory A. Reinhart PhD : The Impact of Nutrition on Skin and Hair Coat, The lams Company, Dayton. 2000; 4: 4-9.
  19. Jae Jin Cho, Young Suk Kim, Jeong Seok Nam, Jeong Hwan Che, Jae Man Yang, Suk Man Lee, Jae Hak Park, Young Sonn Lee : A Study on Ocular and Skin Irritation Test of Shampoos and Rinses, Korean Journal of Lab. Ani. Science, 1995; 11(2): 207-212.