• The Journal of Korean Medicine
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• v.31 no.4
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• pp.178-186
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• 2010

Objectives: This study was to investigate the effect of moxibustion on peripheral blood flow by Doppler ultrasound in post-stroke hemiplegia patients. Methods: Moxibustion was applied on the points of LI4, TE3, TE5 and LI11 on the affected side, and blood flow of the radial artery was measured using the Minimax-Doppler-K device. Blood flow velocity and pulsation index were analyzed before, during, and after moxibustion. Results: The mean value of blood flow velocity in 13 patients showed a tendency of increase during moxibustion, but there was no significant difference in blood flow velocity before and after moxibustion, or pulsation index during and after moxibustion. In addition, among the five patients who showed marked increase tendency on the blood velocity graph, there was significant increase in blood velocity during, and after moxibustion compared with before moxibustion. Conclusions: This study suggests that moxibustion has an effect on peripheral blood flow in stroke patients with hemiplegia. Further validity tests with a larger scale sample are needed for the evidence of its practical use.

• Journal of the Institute of Electronics Engineers of Korea SC
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• v.44 no.2 s.314
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• pp.10-17
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• 2007

The echo signal on ultrasonic transducer is a mixed signal from tissues, blood vessel walls, blood cells and noise. In this mixed-signal, the signal reflected from tissues and blood vessel walls is called clutter. It is necessary to extract pure blood signal from this mixed-signal, when measuring blood flow velocity with medical ultrasonic system The quality of measured blood flow velocity is highly dependent on sufficient attenuation of the clutter signals. In this paper, we suggest a clutter rejection method using ICA For simulation, the echo signals are generated by Field n ultrasonic simulation program In this echo signals, independent signals are separated by using ICA Then the blood signal is obtained from the separated signals. Blood flow velocity is measured by 2D autocorrelation method. We compare ICA clutter rejection method with PCA-based eigen filter method using both measured blood flow velocity profiles by 2D autocorrelation. In simulation results, ICA clutter rejection method can be better applied measuring blood flow velocity in noisy echo signals.

• Proceedings of the IEEK Conference
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• 1999.11a
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• pp.517-520
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• 1999

In this paper, we propose a non-invasive method to estimate blood velocity from the real medical images. To measure the magnitude and direction components associated with the blood velocity, we apply the optical flow analysis algorithm. It is demonstrated that the accuracy of the blood velocity estimate could possibly be increased by segmenting the optical flow region. We call this the Region Optical Flow(ROF) algorithm. We carried out some preliminary experiments using the aorta medical images, and corresponding regional optical flow diagrams are provided.

• Journal of Oriental Neuropsychiatry
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• v.15 no.2
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• pp.173-180
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• 2004

Objectives : The purpose of this study is to investigate the change of cerebral blood flow velocity by different types of suggestion in normal subject. Methods : Suggestion of ascending qi inducement and descending qi inducement which were recomposed from autogenic training, was operated on 60 normal subjects individually. Then cerebral blood flow velocity was examined by Transcranial doppler ultrasonography(TCD) each 5 minutes before and after suggestion. Results : The result shows that cerebral blood flow(CBF) velocity was increased significantly in suggestion of ascending qi inducement and CBF velocity was decreased significally after 1 minute in suggestion of descending qi inducement. Conclusion : Suggestion could have affected to CBF velocity, and also different types of suggestion could have affected to the change of brain blood flow. Various clinical studies should be completed on patients in the future.

• Biomedical Science Letters
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• v.11 no.4
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• pp.435-439
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• 2005

To determine the appropriate concentration of papaverine hydrochloride(PPV) for therapeutic intraarterial infusion against cerebral vasospasm and to measure the mean blood flow velocity of the middle cerebral artery in rabbits. Vasospasm was induced in the experimental groups (3 days after infusion; group 1, n=3, 7 days after infusion; group 2, n=3) and a control group (n=l) by placing a blood clot in the subarachnoid space around the top of the internal carotid siphon. PPV (5 mg/kg) was infused into the internal carotid artery. The vascular diameters of the internal carotid artery (ICA) and middle cerebral artery (MCA) were measured on angiograms before and after infusion. The mean blood flow velocity in the MCA was measured on transcranial doppler sonograms before and 24 hours after infusion. After fixation, the MCA was dissected out, stained, and examined microscopically. After PPV infusion in both groups, vascular dilatation of about $20\%$ was seen. The mean increase in blood flow velocity in the group $1(30\%)$ was smaller than in the group $2(70\%)$. The mean blood flow velocity in the MCA decreased by about $30\%$ in both groups, but increased again after 24 hours nearly to the level before PPV infusion. PPV infusion may be more effective in early stages of vasospasm when vascular walls have fewer histologic changes.

• Journal of Magnetics
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• v.20 no.1
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• pp.47-51
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• 2015

We measured radial arterial pulse signals using a prototype of a clip-type pulsimeter equipped with a permanent magnet and a Hall device, which produced signals through a voltage-detecting circuit. The systolic peak time and the reflective peak time for a temporally pulsed signal were analyzed for an arbitrary pulse wave at one position of a small permanent magnet. The measured value of the peripheral pulse wave velocity was about 1.25-1.52 m/s, demonstrating the accuracy of this new method. To measure the peripheral blood flow velocity, we simultaneously connected the radial artery pulsimeter to a photoplethysmography meter. The average value of the peripheral blood flow velocity was about 0.27-0.50 m/s.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.30 no.4 s.247
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• pp.314-319
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• 2006

To analyze in-vivo blood flow characteristics in a chicken embryo, in-vivo experiment was carried out using micro-PIV technique. Because endothelial cells in blood vessels are subject to shear stress of blood flow, it is important to get velocity field information of the placental blood flow. Instantaneous velocity fields of an extraembryonic blood vessel using a high-speed camera and intravital microscope. The flow images of RBCs were obtained with a spatial resolution of $20\times20{\mu}m$ in the whole blood vessels. The mean velocity field data confirm that the blood flow does show non-Newtonian fluid characteristic. The blood in a branched vessel merged smoothly without any flow separation into the main blood vessel with the presence of a slight bump. This in-vivo micro-PIV measurement technique can be used as a powerful tool in various blood flow researches.

• Journal of International Academy of Physical Therapy Research
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• v.1 no.2
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• pp.99-106
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• 2010

The purpose of this study was to identify the effects of manipulation on the velocity of cerebral blood flow and level of pain in cervicogeinc headache patients. The velocity of cerebral blood flow of 30 cervicogeinc headache patients(male=15, female=15, age=$24.00{\pm}3.60$) and 33 normal subjects(male=15, female=18, age=$23.27{\pm}3.00$) was compared. The 30 cervicogeinc headache patients were divided into suboccipitalis relaxation group, cervical manipulation group, and placebo group, and each were given different interventions. The velocity of cerebral blood flow and pain level was measured before intervention, and 1, 2, 3 weeks after intervention. The velocity of cerebral blood flow was measured with the Transcranial Doppler(TCD), and pain level was measured with visual analog scale(VAS). Blood flow velocity of middle cerebral artery in cervicogeinc headache patients was slower than those in healthy subjects. Physical therapy intervention did not have significant effect on velocity of cerebral blood flow, but slowly decreased at intervention for pain level increased. The suboccipitalis relaxation group and cervical manipulation group showed significant effect in decreasing pain level compared to the placebo group(p<.05). Directly applied manipulation therapy in the neck area not only has effect on joint of cervical and soft tissue but also on blood vessels and nerves which pass the neck area, and because of those results of manual therapy seems to help recovery.

• Biomedical Science Letters
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• v.16 no.2
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• pp.113-118
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• 2010

The purpose of this study was to investigate the effects of angular velocity on muscle strength and blood constituent. Subjects was classified into two groups, which were $60^{\circ}/sec$ angular velocity group (n=8), and $240^{\circ}/sec$ angular velocity group (n=8). Each group was applied to perform the isokinetic exercises on extensor muscle group for each 7 times in 10 set (3 days per a week for 3 weeks). Muscle strength was measured using peak torque of quadriceps femoris and blood constituent was measured using RBC, WBC and Hb. The peak torque was more significantly increased after 3 weeks application of $60^{\circ}/sec$ angular velocity group than $240^{\circ}/sec$ angular velocity group. The RBC and Hb were more significantly increased after 3 weeks application of $60^{\circ}/sec$ angular velocity group than $240^{\circ}/sec$ angular velocity group. But WBC was more significantly increased after 3 weeks application of $240^{\circ}/sec$ angular velocity group than $60^{\circ}/sec$ angular velocity group. These results indicate that $60^{\circ}/sec$ angular velocity isokinetic exercise application were effective treatment strategy on increase of muscle strength. But $240^{\circ}/sec$ angular velocity isokinetic exercise application were effective treatment strategy on immune protect system.

• 한국전산유체공학회:학술대회논문집
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• 2008.03b
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• pp.6-9
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• 2008

Analyzing the characteristics of blood flow in the blood vessels is very important to diagnose the circulatory diseases. In order to investigate the hemodynamic characteristics in vivo, the measurements of blood flows inside the extraembryonic arterial and venous blood vessels of chicken embryos were carried out using an in vivo micro-PIV technique. The circulatory diseases are closely related with the formation of abnormal hemodynamic shear stress regions, thereby it is important to get blood velocity and vessel's morphological information according to the vessel configuration and the flow conditions. In this study, the flow images of RBCs in blood vessels were obtained using a high-speed CMOS camera with a spatial resolution of approximately 14.6${\mu}$m${\times}$14.6${\mu}$m in the whole circulation network of blood vessels. The blood flows in the veins and arteries show steady laminar and unsteady pulsatile flow characteristics, respectively. The mean blood flows merged (in veins) and bifurcated (in arteries) smoothly into the main blood vessel and branches, respectively, without any flow separation or secondary flow which accompanying large variation of shear stress. Vorticity was high in the inner regions for both types of vessels, where the radius of curvature varied greatly. The instantaneous flows in the arterial blood vessels showed noticeable pulsatility due to the heart beat, and the main features of the velocity waveforms, including pulsatile shape, retrograde flow, mean velocity, maximum velocity and pulsatile frequency, were significantly dependent on the pulsatile condition which dominates the arterial blood flow. In near future, these in vivo experimental results of blood flow measured in various extraembryonic blood vessels would be very useful to understand the hemodynamic characteristics of human blood flows and various blood flow researches for clinically useful hemodynamic discoveries as well.