• 동의생리병리학회지
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• 제26권6호
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• pp.934-939
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• 2012

To investigate and characterize basic patterns of prehypertension. Participants were divided into three groups; ideal blood pressure(n=40), prehypertension(n=62), and stage 1 hypertension groups(n=68) according to the JNC 7 standards. They answered questionnaire asking various symptoms and received clinical examination. Data were collected and analyzed in the focus of three Zheng patterns, cold-heat, deficiency-excess and four major hypertension types. Analysis of variance was used to find differences among groups. In addition, relationship between the cold-heat trends and risk factors of hypertension were analyzed using Pearson's correlation analysis. Three risk factors; age, body mass index (BMI), and fasting blood sugar (FBS) showed intergroup differences. Statistical significances were revealed in the cold-heat pattern and two hypertension subtypes. The cold scores decreased from $4.8{\pm}1.84$ to $3.9{\pm}1.88$ and $3.7{\pm}1.27$ (p=0.022), while the heat increased from $1.9{\pm}1.32$ to $2.8{\pm}1.72$ and $2.8{\pm}1.48$ (p=0.009). Additionally two hypertension subtypes, the excessive liver fire, and the yin-yang deficiency showed significant differences. Cold had negative correlations with blood pressure (both systolic and diastolic), BMI, triglyceride, and FBS. Heat had positive correlations with systolic blood pressure, BMI, triglyceride, and FBS. Prehypertension could be characterized by using the cold-heat patterns. The cold-heat are correlated with Blood pressure, BMI, blood lipids and sugar.

• 대한의용생체공학회:의공학회지
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• 제23권4호
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• pp.323-327
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• 2002

만성 당뇨병 질환자는 일 2회 이상 모세혈액을 채취하여 혈당검사를 행함으로써 자신의 혈당 수준을 지속적으로 관리해야 한다. 모세혈액 채취를 위하여 채혈침으로 빈번하게 피부관통을 행해야 하므로 채혈시 뒤따르는 통증은 대단히 중요한 문제이다. 본 연구에서는 기존의 수동 및 자동 채혈침들이 가지는 통증 유발요인들을 모두 최소화하는 기전을 고안하였다. 경사각을 이루는 taper형 스프링, 채혈침을 일관성있는 방향으로 이동시키는 guiding tunnel, 현존하는 기술로 제조할 수 있는 가장 가는 30G 채혈침을 적용함으로써 통증을 최소화 하였다. 침의 침투 깊이를 피하 2mm로 제한하여 통증을 최소화하는 동시에 출혈량을 감소시켰다. 또한 환자 간 감염 및 이차 감염을 방지하기 위하여 사용이 용이한 재사용 방지기전을 설치하였다. 당뇨질환자. 일반인 및 간호실습생들을 대상으로 한 임상실험 결과 통증 및 사용편의성과 안전성 모두 우수한 것으로 입증되었다. 일회 채혈로 모두 성공적인 혈당검사가 가능하였으며 단순한 구조의 소형화 ·일체화된 일회용 자동채혈침의 형태로 구현하였다 본 연구결과는 혈담검사를 위한 모세혈액 채취시 최적의 방법을 제공하였으며 실용성 또한 우수한 것으로 판단되었다.

• 한국농촌간호학회지
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• 제1권1호
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• pp.21-31
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• 2006

Purpose: This purpose of this study was to examine the effect of a walking exercise program on blood pressure and related factors in older patients with hypertension living in rural areas. Method: The participants were 233 patients with hypertension, 60years or age or over, who were registered at one of 36 public health centers in North Chung Cheong Province and agreed to participate in this study. The program was implemented for 12 weeks from Dec. 2005to Feb. 2006. The data were collected before and right after the program and paired t-test was used to analyze the data. Analysis was done with the SPSS program. Result: Systolic pressure (t=7.460, p=0.000) and diastolic pressure (t=5.309, p=0.000) decreased significantly. Total cholesterol l (t=-9.991, p=0.000), LDL cholesterol and HDL cholesterol (t=-3.180, p=0.000) all increased significantly. There was no change in weight or obesity level. Blood sugar (t=2.218, p=0.028) decreased significantly. Knowledge of hypertension increased significantly as did the self-care behavior of these patients with hypertension. Conclusion: The walking exercise program was found to be effective to control blood pressure in older patients with hypertension in rural areas and to help HDL cholesterol, knowledge of hypertension, and self-care behavior of hypertension increase greatly, while blood sugar level decreased.

• 디지털융복합연구
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• 제19권9호
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• pp.257-269
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• 2021

논문은 심탄도(BCG, Ballistocardiogram) 센서를 이용하여 생체신호 데이터를 비침습, 무구속적인 방식으로 수집하고, ICT 기술과 고성능 컴퓨팅 환경에서 인공지능 기계학습 알고리즘을 활용하여 데이터 기반 혈당 예측 알고리즘 모델 개발 및 검증하는 방법을 제시하고 연구하는 것이다. 혈당수치 예측모델은 MLP 아키텍처에 입력노드는 심박수, 호흡수, 심박출량, 심박변이도, SDNN, RMSSD, PNN50, 나이, 성별이며, 은닉층 7개를 사용하였다. 실험 결과는 5회 실험한 학습데이터의 평균 MSE, MAE 및 RMSE 값은 각각 0.5226, 0.6328 및 0.7692이며 검증데이터 평균 값은 각각 0.5408, 0.6776, 0.7968이었으며, 결정계수(R2) 수치는 0.9997의 결과를 보였다. 데이터를 기반으로 한 혈당수치를 예측하는 모델을 표준화하고 데이터셋 수집과 예측 정확성을 검증하는 연구가 계속적으로 진행된다면 비침습 방식의 혈당 수준 관리에 활용될 수 있을 것으로 사료된다.

• 한국산학기술학회논문지
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• 제10권9호
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• pp.2451-2459
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• 2009

통증이 거의 없는 새로운 모세혈액 채혈기법인 진공자동채혈법(vacuum assisted auto-lancing)의 정확도를 분석하고자 전형적인 대체부위인 전완(팔) 부위에서 채혈하여 측정한 혈당값을 표준 채혈부위인 정맥 및 손가락에서 채혈하여 측정한 혈당값과 비교, 분석하는 연구를 수행하였다. C대학교병원을 내원한 531명의 환자들을 대상으로 왼손 집게손가락 끝과 왼쪽 전완 부위에서 말초혈액의 혈당을 측정하였고, 곧바로 정맥 채혈하여 혈당을 측정하였다. 전완 부위 혈당 평균값이 손가락보다 정맥 혈당값에 더욱 가까웠으나 이들 간의 차이는 약 10 mg/dL 범위에 불과하여 임상적으로는 동일한 값들로 볼 수 있었다. 측정값들 간에 상관분석을 수행한 결과 손가락과 정맥 채혈의 혈당값 간의 상관계수는 0.94, 전완 부위와 정맥 혈당값 간의 상관계수는 0.92, 또한 전완 부위와 손가락 채혈 간의 상관계수는 0.94로 모두 매우 유의한 상관관계를 보였다(p<0.001). 따라서 대체부위인 전완 부위 혈당검사의 정확도가 실험적으로 입증되었다. 손가락 혈당검사는 상당한 채혈 통증이 수반되어 당뇨 환자들이 자가 검사를 기피하는 주요 원인이 되지만, 전완 부위에서 진공자동채혈하면 통증이 거의 없으므로 만성 당뇨환자들의 자가 질환관리를 위해 매우 유용하리라 기대된다.

• 대한간호학회지
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• 제44권6호
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• pp.672-681
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• 2014

Purpose: The purpose of this study was to investigate the effects of using a Coaching Program on Comprehensive Lifestyle Modification with pregnant women who have gestational diabetes. Methods: The research design for this study was a non-equivalent control group quasi-experimental study. Pregnant women with gestational diabetes were recruited from D women's hospital located in Gyeonggi Province from April to October, 2013. Participants in this study were 34 for the control group and 34 for the experimental group. The experimental group participated in the Coaching Program on Comprehensive Lifestyle Modification. The program consisted of education, small group coaching and telephone coaching over 4weeks. Statistical analysis was performed using the SPSS 21.0 program. Results: There were significant improvements in self-care behavior, and decreases in depression, fasting blood sugar and $HbA_1C$ in the experimental group compared to the control group. However, no significant differences were found between the two groups for knowledge of gestational diabetes mellitus. Conclusion: The Coaching Program on Comprehensive Lifestyle Modification used in this study was found to be effective in improving self-care behavior and reducing depression, fasting blood sugar and $HbA_1C$, and is recommended for use in clinical practice as an effective nursing intervention for pregnant women with gestational diabetes.

• Journal of Korean Biological Nursing Science
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• 제11권1호
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• pp.14-22
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• 2009

Purpose: This study was conducted to examine the clinical factors which affected the amount and the duration of infusion of intravenous (IV) heparin on ischemic stroke. Method: A cross-sectional descriptive study was designed to examine the factors. A total of 101 patients with ischemic stroke from a University hospital in G-city, Korea from January to December, 2006 were participated in this study. Data were analyzed by t- and ANOVA test, correlation coefficient, and stepwise multiple linear regression analysis. Result: This study showed that the patients who have been temporarily stopped to infuse iv heparin for more than one hour, had cardioembolic stroke, and had the lower count of initial red blood cell (RBC) had significantly lower amount of iv heparin infusion per body surface. In addition, this study founded that the patients with lower count of initial RBC and the lower level of initial blood sugar were significantly less likely to have the lower length of iv heparin infusion. Conclusion: Continuous monitoring and controlling the count of RBC and the level of blood sugar are needed to increase the efficacy of iv heparin therapy on ischemic stroke. Further empirical studies should be conducted to support the results of this study.

• 한국IT서비스학회지
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• 제17권1호
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• pp.91-103
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• 2018

This study developed a prediction model using machine learning technology and predicted the success of health consulting by using life log data generated through u-Health service. The model index of the Random Forest model was the highest using. As a result of analyzing the Random Forest model, blood pressure was the most influential factor in the success or failure of metabolic syndrome in the subjects of u-Health service, followed by triglycerides, body weight, blood sugar, high cholesterol, and medication appear. muscular, basal metabolic rate and high-density lipoprotein cholesterol were increased; waist circumference, Blood sugar and triglyceride were decreased. Further, biometrics and health behavior improved. After nine months of u-health services, the number of subjects with four or more factors for metabolic syndrome decreased by 28.6%; 3.7% of regular drinkers stopped drinking; 23.2% of subjects who rarely exercised began to exercise twice a week or more; and 20.0% of smokers stopped smoking. If the predictive model developed in this study is linked with CBR, it can be used as case study data of CBR with high probability of success in the prediction model to improve the compliance of the subject and to improve the qualitative effect of counseling for the improvement of the metabolic syndrome.

• 한국환경보건학회지
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• 제31권1호
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• pp.47-54
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• 2005

To evaluate the hypoglycemic effect of propolis, streptozotocin (STZ) induced diabetic rats were divided into 4 groups such as, diabetic control group, low dose of propolis (0.1 ml) group, medium dose of propolis (0.3 ml) group and high dose of propolis (0.9 ml) group and feeded with propolis extracts for 30 days. After experiment, oral glucose tolerance test (Oral GTT) was carried, and 16 hours fasting blood sugar levels, body weights, blood lipid levels were measured. Finally, pancreatic histopathological study was performed. In conclusion, the propolis is effective to the treatment diabetes due to the reduction of the blood sugar level and the regeneration of the damaged $\beta$-cells shown in streptozotocininduced diabetic rats.

• Journal of Korean Biological Nursing Science
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• 제2권1호
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• pp.20-33
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• 2000

The author was used for the ICR mouse and induced diabetes with the streptozotocin(50mg/kg)and alloxan(40mg/kg). After the testing and the identifying the diabetes, the histological changes of the glomerulus, blood test for the values of blood sugar, and urine test for the values of urine protein were investigated. The results are as follows : 1. The values of high blood sugar appeared from the 2 group were about $378mg/d{\ell}{\sim}709mg/d{\ell}$, in the treated groups with the streptozotocin and alloxan. The glycosuria were obviously continued from the 2 weeks to the 12 weeks of the streptozotocin and the alloxan treated groups and the proteinuria was ${\pm}{\sim}+$ in the 4 weeks and 8 weeks of streptozotocin treated group and were + in all the 12 weeks. The ketonuria were generally negative. 2. In the view of the light microscope, there was no significant histological changes until the 8 weeks. However, in the 12 weeks group treated with the streptozotocin, the mesangial matrix of glomerulus increased Bowman's capsules adhered to each other and changed them to the crescence shapes because of increasing the exothelial cells.