Pattern Analysis in Patients with Hypertension grades

고혈압 단계별 변증특성 분석

  • Yang, Chang Sop (Informatics Development & Management Group, Korea Institution of Oriental Medicine) ;
  • Kim, Youn Geun (Informatics Development & Management Group, Korea Institution of Oriental Medicine) ;
  • Kim, Chang Seok (Informatics Development & Management Group, Korea Institution of Oriental Medicine) ;
  • Kim, Chul (Informatics Development & Management Group, Korea Institution of Oriental Medicine) ;
  • Song, Mi Young (Informatics Development & Management Group, Korea Institution of Oriental Medicine)
  • 양창섭 (한국한의학연구원 정보개발운영그룹) ;
  • 김영은 (한국한의학연구원 정보개발운영그룹) ;
  • 김창석 (한국한의학연구원 정보개발운영그룹) ;
  • 김철 (한국한의학연구원 정보개발운영그룹) ;
  • 송미영 (한국한의학연구원 정보개발운영그룹)
  • Received : 2012.09.14
  • Accepted : 2012.10.23
  • Published : 2012.12.25

Abstract

To investigate and characterize basic patterns of prehypertension. Participants were divided into three groups; ideal blood pressure(n=40), prehypertension(n=62), and stage 1 hypertension groups(n=68) according to the JNC 7 standards. They answered questionnaire asking various symptoms and received clinical examination. Data were collected and analyzed in the focus of three Zheng patterns, cold-heat, deficiency-excess and four major hypertension types. Analysis of variance was used to find differences among groups. In addition, relationship between the cold-heat trends and risk factors of hypertension were analyzed using Pearson's correlation analysis. Three risk factors; age, body mass index (BMI), and fasting blood sugar (FBS) showed intergroup differences. Statistical significances were revealed in the cold-heat pattern and two hypertension subtypes. The cold scores decreased from $4.8{\pm}1.84$ to $3.9{\pm}1.88$ and $3.7{\pm}1.27$ (p=0.022), while the heat increased from $1.9{\pm}1.32$ to $2.8{\pm}1.72$ and $2.8{\pm}1.48$ (p=0.009). Additionally two hypertension subtypes, the excessive liver fire, and the yin-yang deficiency showed significant differences. Cold had negative correlations with blood pressure (both systolic and diastolic), BMI, triglyceride, and FBS. Heat had positive correlations with systolic blood pressure, BMI, triglyceride, and FBS. Prehypertension could be characterized by using the cold-heat patterns. The cold-heat are correlated with Blood pressure, BMI, blood lipids and sugar.

Keywords

Acknowledgement

Grant : 생애 전주기 고혈압 예방관리 시스템

Supported by : 한국한의학연구원

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