• 대한한방내과학회지
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• 제20권1호
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• pp.198-209
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• 1999

A thrombus is a mass formed from the constituents of the blood within the vessels or the heart during life. The process of its formation is known as thrombosis, It has been generally accepted that Holotrichia is an useful medicine for thrombosis. The rate of fibrinolysis of Holotrichia extracts increase as incubation times. Especially 52 days, the effect on the extracts has an maximum increased fibrinolytic activity, Heat-and-pH-stability of the extract on fibrinolysis is relative to temperature, At $37^{\circ}C$, it has activating effect between pH 4 and pH 12. At higher temperature, especially $80^{\circ}C$, an excessive increase in temperature has a deactivating effect on the extracts. Optimal pH of the extract on fibrinolysis is between pH 7.0 and pH 8.5, it is effective within a relatively broad pH range. In experiments of various inhibitors of Holotrichia extracts fibrinolytic activity, there are strong inhibitive effect on SBTI and Aprotinin, and a few inhibitive effect on DFP and t-AMCHA, no effect on PSMB and TLCK. Holotrichia extracts mixing with fibrinogen are observed Electron microscopy. it shows partially erosive-shaped fibrinolytic activity. In a SDS-PAGE of the extract having the fibrinolytic activity, three bands are found, protein 1, 2 and 3 having a molecular weight of 30,000, 45,000 and 60,000 Dalton.

• 동의생리병리학회지
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• 제16권3호
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• pp.435-442
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• 2002

Phlegm is defined as the static fluid in excess in one or more parts of the body. It is not only a pathologic product but also a pathogen itself. However, as it says Phlegm is another title for the body fluid. phlegm can be physiological. In Hyungsang medicine. since the Hyungsang which an individual shows determines his or her illness. the principle to treat phlegm also varies according to the individual's Hyungsang. Thus, the author reviewed ‘Jisan’s Special Lectures for Clinicians’ and summarized the concepts and diagnostics of phlegm, and treatment and regimens by Hyungsang medicine. The concepts of phlegm : Phlegm is not only a pathologic product of disharmony of Jung(精), Ki(氣), Shin(神) and Hyul(血) but also a driving force to mature and transform these constituents. Phlegm is another designation for the Fluid. Phlegm can act as an alternative substance or buffering agent. If we describe our body as the habitat of worms. phlegm could be the inhabitant. Diagnostics of phlegm : The infraorbital areas have a dark-gray or blackish coloring. A man who is feminine or a woman who is masculine tends to develop phlegm. One of the major signs of phlegm is pain in Chungwan(中脘). The color of the skin does not change. Treatment of phlegm by Hyungsang medicine. For the Jung type(精科) and the Hyul type(血科), phlegm treatment is to supply Jung and Blood or eliminate Damp-phlegm. The man needs tonifying herbs and the woman needs herbs which promote the flow of Ki(氣). Children and the aged are. tegardless of the nature of disease, to be warmed and supplemented. For the heavy man. treatment is to supplement Ki and eliminate Damp; for the slim man. treatment is to supplement Yin(陰) and purge Heat.

• 동의신경정신과학회지
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• 제15권1호
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• pp.9-25
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• 2004

Behavioral characteristics of Attention Deficit Hyperactivity Disorder(ADHD) is one of the most common mental disorders among children.child psyachiatry. Inattention, Hyperactivity that is done by hyperkinesis or minimal brain dysfunction is major sypmton in ADHD, But etiology and pathological facor of ADHD is very much or unkown.. We brought to about a Study on the Oriental - medical pathologic Understanding about Inattention, Hyperactivity symptom in ADHD within Don yui bo gam Book are as follows. 1. Oriental medical pathologic concepts about Inattention, Hyperactivity are continuous with process of Yang Qi(陽氣), an unbalance of qi(氣) and shen ming(神明), excess of seven emotions(七情), pathology of Huo(火). 2. Immanent factors in inattention, Hyperactivity are improper diet, overtiredness and seven emotions, are continuous with pathological process of the heart, liver, gall bladder, spleen, stomach, kidneys. 3. In oriental medicine, considered as a child's qi of shao yang, dynamic physiological feature, excess and want of yin and yang, organs and bowels, immanently imbalance in growth rather than a child's mental disorder 4. Inattention, looseness in ADHD-PI type are continuous with forgetfulness, improper overtiredness, shortage of qi, the interior heat syndrome due to yin deficiency within Don yui bo gam Book 5. Hyperactivity, impulsive actions in ADHD-C type are continuous with sudden palpitation, severe palpitation, delirium, fidgeting due to deficiency, fidgetiness, hyperactivity of huo due to yin deficiency, fever, febrile disease with accumulation of blood.

• 동의신경정신과학회지
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• 제21권4호
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• pp.99-112
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• 2010

Objectives : This study was to investigate the associations of Parent Stress Index(PS]). Way of Coping Checklist(WCC). and Diagnostic System of Oriental Medicine(DSOM) in mothers of elementary school children. Methods: In the study. K-PSI-SF. WCC. and DSOM were carried out on 202 mothers of O Oelementary school children during June. 2010. Cross tabulation analysis was used to verify the association of PSI. WCC and DSOM. Results: 1. The most common pathogenic factor was Dampness(濕) in total subjects. 2. The score of problem-focused coping methods showed significant difference in PSI grades. 3. The zp and sc10 of Qi deficiency(氣虛), Blood deficiency(血虛), Qi-Stagnation(氣滯), Insufficiency of Yang(陽虛), Heat(熱), Dampness(濕), Dryness(燥), Liver(肝), Heart(心), and Kidney(腎) showed significant difference in PSI grades. 4. The score of total PSI and PSI subscale had negative correlations with problem-focused coping methods 5. The score of total PSI had positive correlations with Qi-Stagnation (氣滯), Dampness(濕), Dryness(燥), Heart(心), and Kidney(腎) in total subjects. Conclusions : This study provides insights on associations of parenting stress coping methods and diagnostic system in Oriental Medicine. Furthermore, the study shows positive correlations among Qi-Stagnation (氣滯), Dampness(濕), Dryness(燥), Heart(心), Kidney(腎) and PSI, and negative correlations between PSI and Problem-focused coping methods, all with statistical significance.

• 한국화재소방학회논문지
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• 제26권3호
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• pp.40-48
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• 2012

심하게 소손된 화재현장은 남아 있는 잔존물만으로 초기 화재의 유형을 판단하기 곤란할 때가 많다. 화재로 인해 사람이 사망하였을 경우 혈중 헤모글로빈(Hb)-일산화탄소(CO) 농도는 생존 당시의 화재의 유형을 가늠할 수 있으며 촉진제를 사용한 급격한 화재의 경우 열기와 유독가스로 인해 재실자의 생존은 화재진행속도와 비례되어 체내 Hb-CO 농도는 낮았으며, 훈소와 같이 서서히 진행되는 연소의 경우 오랜 시간 호흡하면서 체내에 축적되는 CO 농도는 증가하였다. 이러한 인체의 Hb-CO 농도를 분석하면 생존 시 어떠한 형태의 화재에 노출되었는지 알 수 있다. 휘발유로 분신한 자살의 경우를 포함해 훈소성 화재사에 이르기까지 Hb-CO 농도는 3 %에서 최고 93 %로 다양한 농도를 보였다.

• 동의생리병리학회지
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• 제22권1호
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• pp.262-266
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• 2008

We plan to make the standardization of the pattern identifications for stroke and differentiate them by tongue diagnosis. We make a case report form which has questionnaires for tongue diagnosis in stroke patients. And we collected cases from the multi center network which consists of twelve university hospitals and one local hospital. The cases confirmed by diagnosis of medical specialists and residents are 321 cases. They are divided into Qi Defficiency 30.84%, Dampness& Phlegm 25.55%, Fire & Heat 22.43%, Eum Defficiency 18.69% and Blood Stasis 2.49%. We analyzed the markers which classified into the color of tongue body, the color of fur, the quality of fur, the dryness of tongue, the shape of tongue. To make a stroke pattern identification standard, we must try variable ways.

• 동의생리병리학회지
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• 제22권2호
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• pp.469-480
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• 2008

This study was performed to investigate using of herbal medicine based on pattern identification of symptoms, such as Qi deficiency pattern, Yin deficiency pattern, Phlegm -dampness pattern, Static blood pattern, Fire-heat pattern. These patterns settled by Korean Standard Differentiation of the Symptoms and Signs for Stroke in 2005. This study was done with 177 patients in Daejeon University Oriental Medical Hospital in the period of November 2006 to July 2007. Among the five types of pattern identification, Phlegm -dampness pattern showed significantly high frequency especially in 3 weeks after stroke. The sort of herbal medicine was 43 and Dodamhwalhyoel-tang(26.61%), Sunhwanki 1 hobang(14.52%), Banhabaekchulcheonma-tang(4.84%), Ansinchongnoi-tang(4.84%), Chongryuldodam-tang(4.03%) were most frequently used. Especially Dodamhwalhyoel-tang showed significantly high frequency in 2 weeks after stroke. Based on these results, it is suggested that more practical Korean Standard Differentiation of the Symptoms and Signs for Stroke would be established through continuous clinical studies by giving weight on relationship between herbal medicine and pattern identification.

• 분석과학
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• 제23권4호
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• pp.331-346
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• 2010

과불화 화합물(perfluorinated compounds, PFCs)은 열과 산성, 염기 등과 같은 화학적 조건에 높은 안정성을 갖고 있을 뿐만 아니라 발수성, 발유성, 방오성과 제품 친화적인 특징 때문에 다양한 산업소재로 활용되고 있으며, 근래에 이르러서는 대규모로 생산되고 있는 산업제품이다. 그러나 난분해성으로 인하여 환경 내에 잔류하여 전세계적으로 널리 분포하고 있을 뿐만 아니라 인체나 동식물에 이르는 생물체에 이르기까지 오염되어 분포하고 있다. 또한 인체를 비롯한 생물체에 장기적으로 축적될 시 암등을 유발할 가능성이 있다고 보고됨에 따라 이에 대한 관심이 증가하고 있다. 최근 스톡홀름 협약에서 과불화 화합물을 새로운 환경지속성오염물질(persistent organic pollutants, POPs)로 규정함에 따라 이에 대한 분석법의 중요성이 대두되고 있다. 본 연구에서는 다양한 환경 및 생체 시료 내에서 과불화 화합물의 분석법에 대한 연구의 중요성 및 문제점과 더불어 최근 연구 동향을 소개하였다.

• 대한의용생체공학회:의공학회지
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• 제20권2호
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• pp.191-198
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• 1999

바이오피드백은 혈압 심박율, 말초체온, 호흡, 근전도 등과 같이 자율신경에 의해 지배받는 신체 기능들을 훈련을 통해 스스로 조절할 수 있게 하여 자율신경의 이상으로 인한 여러 가지 질병들을 치료할 수 있게 하는 방법이다. 븐 논문에서는 주정중독증 환자들을 대상으로 바이오피드백 훈련을 실시할 수 있도록 근전도, 호흡, 맥파, 말초체온, 피부전기전도도 등 다섯 가지 신호를 측정할 수 있는 바이오피드백 시스템을 개발하였다. 개발된 시스템을 이용해 주정중독증 환자들을 대상으로 바이오피드백 훈련을 실시하였다 이완 바이오피드백 훈련을 실행하였으며 생체신호변화에 대해 퍼지이론을 적용하여 긴장상태를 판단하였다. 8명의 주정중독증 환자들이 실험에 참가하였으며 측정된 데이터를 분석한 결과는 다음과 같다. 1) 환자 군은 일반인에 비해서 높은 긴장도 값을 보였다. 2) 환자들의 긴장도 값은 훈련 회수가 증가함에 따라 감소하는 추세를 보였다.

• 대한한의학회지
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• 제32권5호
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• pp.25-40
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• 2011

Objectives: This study was performed to assess whether herbal medicine and acupuncture before in vitro fertilizationembryo transfer (IVF-ET) is effective on clinical pregnancy. Methods: From May 2010 to January 2011, a prospective analysis study was performed in 38 patients planning to undergo IVF-ET after taking herb medicine and acupuncture treatment. This study investigated the pregnancy rate and analyzed the change of dysmenorrhea by visual analog scale (VAS), body heat and condition of premenstrual syndrome (PMS), vaginal discharge and menstruation status. Results: 1. During herbal medicine and acupuncture treatment, five patients (13.16%) naturally became pregnant and six patients (15.79%) withdrew. After treatment, 15 patients (39.47%) received IVF-ET, 12 patients (31.58%) did not. 2. The biochemical pregnancy rate was 26.67%, the clinical pregnancy rate 26.67%, miscarriage rate 25% and ectopic pregnancy rate was 0%. 3. After treatment, PMS, dysmenorrhea and dysmenorrhea VAS was significantly decreased and the overall menstrual status improved. 4. After treatment, temperature difference of CV17-CV12 and CV4-CV12 increased, but it was not a statistically significant difference. 5. After treatment, decrease of hemoglobin and protein and increase of total bilirubin and creatinine were statistically significant. All the blood test results were within normal levels which proves safety of treatment. Conclusions: This study suggests that herbal medicine and acupuncture treatment before IVF-ET shows similar pregnancy rates with existing rates, but contributes to increasing the possibility of natural pregnancy.