• 한국환경과학회지
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• 제6권1호
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• pp.69-73
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• 1997

Endotoxin from the cell wall of marine V. vujnificus was .extracted using the hot phenol-water method, injected endotoxin into rat, and tested the toxic effect of endotoxin on the blood component In rat blood. The results showed that blood glucose, blood urea nitrogen, white blood cell, and reticulocyte were Increased and red blood cell was the same as the number of control group(normal blood), but platelet was decreased. Above results suggested that endotoxin induced a malfunction of liver and that the Increase of white blood cell was for the removal of foreign toxic substance.

• Journal of Life Science
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• 제10권2호
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• pp.9-11
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• 2000

Lipopolysaccharide (LPS) and cell wall protein-A (CWP-A) were extracted from the cell wall of Vibrio vulnificus, Escherichia coli and Salmonella typhimurium. LPSs and CWP-As were injected into rat and the changes of the following blood components were examined. The change of the number of white blood cell (WBC), red blood cell (RCB), platelet (PLT), blood urea nitrogen (BUN) and blood glucose in rat blood and interferon (IFN) activity change by LPS and CWP-A were measured. WBC, RETI, PTT, and BUN were increased and RBC and blood glucose were increased slightly, but PLT was decreased.

• 전자공학회논문지SC
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• 제44권2호
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• pp.10-17
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• 2007

의료용 초음파 시스템으로 혈류 속도를 측정할 때, 순수한 혈류 신호의 검출이 필요하다. 초음파 트랜스듀서를 통해 들어오는 반사 신호는 체세포 조직(tissue), 혈관 벽(blood wall), 적혈구(red blood cell), 잡음(noise) 등이 혼합된 신호이다. 혼합된 신호에서 체세포 조직과 혈관 벽 신호를 클러터(clutter)라고 한다. 본 논문에서는 ICA(independent component analysis)를 적용하여 클러터 신호와 잡음을 효과적으로 제거하는 방법을 제시하였다. Field II 초음파 시뮬레이션 프로그램을 이용하여 초음파 반사 신호를 생성하고, ICA를 사용하여 각 독립 신호들을 분리, 클러터 신호를 제거하여 혈류 신호를 추출했다. 추출전 혈류신호를 2D 자기상관(autocorrelation) 방법으로 혈류 속도를 측정했다. 그리고 PCA(principal component analysis)방법을 적용한 고유 필터(autocorrelation) 방법으로 클러터를 제거한 결과와 비교하였다. 그 결과 잡음 환경에서의 혈류 속도 측정에 ICA 방법이 우수한 적용 결과를 보였다.

• 유체기계공업학회:학술대회논문집
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• 유체기계공업학회 2004년도 유체기계 연구개발 발표회 논문집
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• pp.754-760
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• 2004

The miniaturization and integration are trend of modern blood analyses. Micro-Bio-Fluidics plays an important role in a micro blood analysis system. In this paper, analysis and design technology for blood analysis system is presented. Numerical simulations of a blood flow in micro separator and reservoir are conducted. As a result, we suggest on-chip micro separator, which performed plasma separation from whole blood in micro channels.

• 대한의용생체공학회:의공학회지
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• 제32권2호
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• pp.109-117
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• 2011

Assuming that photons absorbed by a vessel do not have acute variations, DC component reflect the basal blood volume (or diameter) before blood pulsation. Vascular stiffness and reflection is influenced by changes in basal blood volume (or diameter). This paper describes analysis of the characteristic variations of vascular stiffness, according to relative variations in DC components of the PPG signal (25-75%). For quantitative analysis, we have used parameters that were proposed previously, reflection and stiffness index, and the second derivative of PPG waveform, b/a and d/a. Significantly, the vascular stiffness and reflections were increased according to increase in DC component of the PPG signal for more than about 3% of baseline values. The systolic blood pressure were increased from $113.1{\times}13.18$ to $116.2{\times}13.319$ mmHg, about 2.76% (r = 0.991, P < 0.001) and the AC component of the PPG signal were decreased from $2.073{\times}2.287$ to $1.973{\times}2.2038$ arbitrary unit, about 5.09% (r = -0.993, P < 0.001). It is separated by DC median and correlation analysis was performed for analyzing vascular characteristics according to instantaneous DC variations. There are significant differences between two correlation coefficients in separated data.

• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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• pp.276.3-277
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• 2003

A simple, accurate GC analytical technique for the determination of phthalates. commonly used as plasticizers during the manufacturing process of PVC bags, in blood component preparations was developed and validated. The blood component preparations were extracted with n-hexane. The n-hexane layer was evaporated to dryness and the residue was dissolved in 1 $m\ell$ of n-hexane and analyzed by GC and GC/MS. (omitted)

• The Journal of Korean Physical Therapy
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• 제14권3호
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• pp.308-322
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• 2002

The purpose of this study was to investigate the influence of the Cardiopulmonary function and Blood component to aerobic exercise. This were measured performance for 15 minutes. This study included 14 healthy individuals, 7 males and 7 females who were aged from 19 to 25 years. 1. After exercise heart rate was increased by on average of 93.7 beat/min as compared with rest. 2. Before exercise breath rate increased compared with rest and normal recovery need more 10 minutes. 3. Breathing capacity increased compare before with after perfoming exercise and male was less increase than was female. 4. Blood component(WBC, RBC, HB, HCT) showed aslight increased of difference compare before with after perfoming exercise.

• 한국전산유체공학회:학술대회논문집
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• 한국전산유체공학회 2008년도 학술대회
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• pp.186-196
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• 2008

The dependence of the rheological properties of blood on shape, aggregation, and deformability of red blood cells (RBCs) has been investigated using hybrid systems by coupling fluid with solid models. We present a simple approach for simulating blood as a multi-component fluid, in which RBCs are modeled as droplets of acquired biconcave shape. We used lattice Boltzmann method (LBM) due to its excellent numerical stability as a simulation tool. The model enables us to control the droplet static shape by imposing non-isotropic surface tension force on the interface between the two components. The use of the proposed non-isotropic surface tension method is justified by the Norris hypothesis. This hypothesis states that the shape of the RBC is due to a non-uniform interfacial surface tension force acting on the RBC periphery. This force is caused by the unbalanced distribution of the lipid molecules on the surface of the RBC. We also used the same concept to investigate the dynamic shape change of the RBC while flowing through the microvasculature, and to explore the physics of the Fahraeus, and the Fahraeus-Lindqvist effects.

• 한국전산유체공학회:학술대회논문집
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• 한국전산유체공학회 2008년 추계학술대회논문집
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• pp.186-196
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• 2008

The dependence of the rheological properties of blood on shape, aggregation, and deformability of red blood cells (RBCs) has been investigated using hybrid systems by coupling fluid with solid models. We present a simple approach for simulating blood as a multi-component fluid, in which RBCs are modeled as droplets of acquired biconcave shape. We used lattice Boltzmann method (LBM) due to its excellent numerical stability as a simulation tool. The model enables us to control the droplet static shape by imposing non-isotropic surface tension force on the interface between the two components. The use of the proposed non-isotropic surface tension method is justified by the Norris hypothesis. This hypothesis states that the shape of the RBC is due to a non-uniform interfacial surface tension force acting on the RBC periphery. This force is caused by the unbalanced distribution of the lipid molecules on the surface of the RBC. We also used the same concept to investigate the dynamic shape change of the RBC while flowing through the microvasculature, and to explore the physics of the Fahraeus, and the Fahraeus-Lindqvist effects.

• 대한한의학원전학회지
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• 제20권3호
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• pp.67-77
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• 2007

Through the translation and comparative study of the enriching blood and nourishing vital essence(補陰血方劑) in "The Elimination & Supplement about the Famous Prescription Comments(刪補名醫方論)" of "The Golden Mirror of Medicine(醫宗金鑑)" with "The Famous Prescription Comments on Ancient and Modern Times(古今名醫方論)", we confirmed that about 50% of the sentences from "The Elimination & Supplement about the Famous Prescription Comments(刪補名醫方論)" were quoted in "The Famous Prescription Comments on Ancient and Modern Times(古今名醫方論)", and that many of the text were not quoted unchanged, but were revised and supplemented. In organization, the prescription with the fewer number of component drugs is given first, followed by that with more component drugs, and that with similar component drugs is explained subsequently to facilitate understanding. In the prescription notes, it is emphasized that when enriching blood, the invigorative method(補氣法) is very important and that cold or pungent herb should be very carefully used.