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Analysis of Arterial Stiffness Variation by Photoplethysmographic DC Component

광용적맥파 비맥동성분에 의한 혈관경직도 변화 분석

  • Lee, Chung-Keun (Department of Electrical and Electronics Engineering, Yonsei University) ;
  • Shin, Hang-Sik (Department of Electrical and Electronics Engineering, Yonsei University) ;
  • Kong, In-Deok (Department of Physiology, Yonsei Wonju Medical School) ;
  • Lee, Myoun-Ho (Department of Electrical and Electronics Engineering, Yonsei University)
  • 이충근 (연세대학교 공과대학 전기전자 공학과) ;
  • 신항식 (연세대학교 공과대학 전기전자 공학과) ;
  • 공인덕 (연세대학교 원주의과대학 생리학교실) ;
  • 이명호 (연세대학교 공과대학 전기전자 공학과)
  • Received : 2010.11.16
  • Accepted : 2011.03.22
  • Published : 2011.04.30

Abstract

Assuming that photons absorbed by a vessel do not have acute variations, DC component reflect the basal blood volume (or diameter) before blood pulsation. Vascular stiffness and reflection is influenced by changes in basal blood volume (or diameter). This paper describes analysis of the characteristic variations of vascular stiffness, according to relative variations in DC components of the PPG signal (25-75%). For quantitative analysis, we have used parameters that were proposed previously, reflection and stiffness index, and the second derivative of PPG waveform, b/a and d/a. Significantly, the vascular stiffness and reflections were increased according to increase in DC component of the PPG signal for more than about 3% of baseline values. The systolic blood pressure were increased from $113.1{\times}13.18$ to $116.2{\times}13.319$ mmHg, about 2.76% (r = 0.991, P < 0.001) and the AC component of the PPG signal were decreased from $2.073{\times}2.287$ to $1.973{\times}2.2038$ arbitrary unit, about 5.09% (r = -0.993, P < 0.001). It is separated by DC median and correlation analysis was performed for analyzing vascular characteristics according to instantaneous DC variations. There are significant differences between two correlation coefficients in separated data.

Keywords

References

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