• 한국고분자학회:학술대회논문집
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• 한국고분자학회 2006년도 IUPAC International Symposium on Advanced Polymers for Emerging Technologies
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• pp.37-38
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• 2006

Conjugated diacetylene supramolecules are interesting biomimetic materials in view of application to chemical and label-free biological sensors. These supramolecules are unique in changing color from blue to red upon specific binding events. Various binding events including viruses, toxins, glucose, and ionic interactions have been reported detectible. Here, we focus on fabrication of polydiacetylene supramolecule dot array patterns on solid substrates by using a conventional microarrayer. Each dot is found to possess the color-changing property as well as the fluorescence self-emission. This technique allows us, for the first time, to fabricate biochips based on polydiacetylene supramolecules. Label-free detection of small molecules and biological targets will be discussed.

• Journal of International Society for Simulation Surgery
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• 제3권2호
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• pp.49-59
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• 2016

3D printing is also known as additive manufacturing technique in which has been used in various commercial fields such as engineering, art, education, and medicine. The applications such as fabrication of tissues and organs, implants, drug delivery, creation surgical models using 3D printer in medical field are expanding. Recently, 3D printing has been developing for produce biomimetic 3D structure using biomaterials containing living cells and that is commonly called "3D bio-printing". The 3D bio-printing technologies are usually classified four upon printing methods: Laser-assisted printing, Inkjet, extrusion, and stereolithograpy. In the bio-printing, bio-inks (combined hydrogels and living cells) are as important components as bio-printing technologies. The presence of various types of bioinks, however, in this review, we focused on the bio-inks which enables bioprinting efficacy using hydrogels with living cells.

• Smart Structures and Systems
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• 제7권3호
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• pp.185-198
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• 2011

The promise of biomimetic smart structures that can function as sensors and actuators in biomedicine is enormous. Technological development in the field of stimuli-responsive shape memory polymers have opened up a new avenue of applications for polymer-based synthetic actuators. Such synthetic actuators mimic various attributes of living organisms including responsiveness to stimuli, shape memory, selectivity, motility, and organization. This article briefly reviews various stimuli-responsive shape memory polymers and their application as bioactuators. Although the technological advancements have prototyped the potential applications of these smart materials, their widespread commercialization depends on many factors such as sensitivity, versatility, moldability, robustness, and cost.

• Smart Structures and Systems
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• 제7권3호
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• pp.199-211
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• 2011

Using computational modeling, we design a pair of biomimetic microcapsules that exploit chemical mechanisms to communicate and alter their local environment. As a result, these synthetic objects can undergo autonomous, directed motion. In the simulations, signaling microcapsules release "agonist" particles, while target microcapsules release "antagonist" particles and the permeabilities of both capsule types depend on the local particle concentration in the surrounding solution. Additionally, the released nanoscopic particles can bind to the underlying substrate and thereby create adhesion gradients that propel the microcapsules to move. Hydrodynamic interactions and the feedback mechanism provided by the dissolved particles are both necessary to achieve the cooperative behavior exhibited by these microcapsules. Our model provides a platform for integrating both the spatial and temporal behavior of assemblies of "artificial cells", and allows us to design a rich variety of structures capable of exhibiting complex dynamics. Due to the cell-like attributes of polymeric microcapsules and polymersomes, material systems are available for realizing our predictions.

• 한국세라믹학회지
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• 제50권4호
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• pp.257-262
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• 2013

A biomimetic approach was applied for the chemical deposition of calcium phosphate (CaP) coatings on 3 mole% yttrium-stabilized zirconia [3YSZ] powders. The solid-state reaction of 3YSZ powders with the addition of CaP was investigated for the development of biodegradable zirconia ceramics. The solid-state interaction between the 3YSZ matrix powders and the CaP additives differed from the behavior of commercial zirconia matrix powders. The 3YSZ powders were chemically reacted with precursors for the CaP formation. 3YSZ powders were mixed in an aqueous solution of Ca-P precursors and the CaP was precipitated on the surface of the 3YSZ matrix powders. The CaP-doped YSZ powders were calcined at $1100^{\circ}C$ and shaped powder blocks were then fired at $1600^{\circ}C$ for 2 h. The CaP phase formation was investigated using FE-SEM and XRD analysis.

• 대한건축학회논문집:계획계
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• 제33권12호
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• pp.29-39
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• 2017

The building skins are important architectural elements in both functional and aesthetical aspects. This study focuses on developing a responsive facade with autonomous opening and closing behaviors in accordance with environmental conditions and user requirements for natural ventilation for the office building. The pneumatic ETFE panels are applied as the skin materials taking advantage of the efficiency of the inflatable skin of lightness, architectural performance and sustainable material properties. The biomimetic design methodology is taken for its innovative and visionary concept for the facade design. The interpretation of the building facade in analogy to natural organisms delivers functional and aesthetic characters. By exploring the structural movements of the plant pores, the facade control is developed to be autonomous by the parameter values. The facade opening and closing configurations are derived through parametric modeling and visualization programming. Through the application of this study, expected results are to improve user comfort and energy efficiency.

• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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• pp.229.2-230
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• 2003

Extracellular matrix(ECM) is composed of the ground materials(proteoglycan) and nano size diameter fibrous proteins(ex. collagens) that together form a composite-like structure. In this study, fibrous scaffold with biomimetic architecture based on collagen nanofibers interpenetrated in PLGA/chitosan microfibrous matrix. Chitosan was selected for its structure similarity to glycosaminoglycan and neutralizing capacity for PLGA acidic metabolite. Collagen nanofiber were prepared by electrospinning. (omitted)

• 폴리머
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• 제29권3호
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• pp.221-230
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• 2005

복합재료에 있어서 계면상호작용과 상계면은 이를 구성하고 있는 성분의 함량이나 형태 또는 구조와는 관계없이 입자가 충전된 고분자 또는 고분자 블렌드, 섬유강화 복합재료, 나노복합재료 그리고 생체재료 등의 기본적 물성에 매우 중요한 역할을 한다 계면접착에 영향을 미치는 주요 성분들의 역할에 대한 인식과 이에 따른 적절한 표면처리는 관련기술로의 적용뿐만 아니라 다른 여러 연구 및 개발 분야에도 중요한 기술적 진보를 가져다준다. 그러나 모든 복합재료에서 계면과 상계면의 역할이 중요할지라도 이러한 표면처리 방법은 특정 시스템의 특성뿐만 아니라 그 목적에 맞게 적절하게 선택되어야 한다. 본 연구에서는 복합재료 시스템의 두 성분간의 계면상호작용을 향상시켜 최종 복합재료의 요구 물성을 증가시키기 위하여 여러 종류의 표면처리를 행하였으며, 그 결과들에 대하여 고찰하였다.

• 한국재료학회지
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• 제28권1호
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• pp.24-31
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• 2018

This study reports an environment-friendly synthetic strategy to process nickel oxide nanocrystals. A mesoporous nickel oxide nanostructure was synthesized using an environmentally benign biomimetic method. We used a natural rambutan peel waste resource as a raw material to ligate nickel ions to form nickel-ellagate complexes. The direct decomposition of the obtained complexes at $700^{\circ}C$, $900^{\circ}C$ and $1100^{\circ}C$ in a static air atmosphere resulted in mesoporous nickel oxide nanostructures. The formation of columnar mesoporous NiO with a concentric stacked doughnuts architecture was purely dependent on the suitable direct decomposition temperature at $1100^{\circ}C$ when the synthesis was carried out. The prepared NiO nanocrystals were coated on cotton fabric and their antibacterial activity was also analyzed. The NiO nanoparticle-treated cotton fabric exhibited good antibacterial and wash durability performance.

• 한국수산과학회지
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• 제48권1호
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• pp.1-15
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• 2015

Tissue engineering is an emerging, innovative technology to improve or replace the biological functions of damaged tissues and organs. Scaffolds are important materials for tissue engineering as they support cell attachment, migration, and differentiation. Marine sponges naturally contain scaffolds formed by extracellular matrix proteins (collagen and sponging) and strengthened by a siliceous or calcium carbonate skeleton. Coral skeletons are also derived naturally formed by essential calcium carbonate in the form of aragonite, and are similar to human bone. In addition, collagen extracted from jellyfish is a biosafe alternative to bovine and porcine collagen and gained attention as a potential source for tissue engineering. Moreover, cuttlefish bone is an excellent calcium source and can be used to generate bio-synthetic calcium phosphate. It has become a natural candidate for biomimetic scaffolds. This review describes the use of natural products derived from marine invertebrates for applications in bone tissue engineering based on studies from 2008 to 2014.