• 대한의용생체공학회:의공학회지
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• 제25권3호
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• pp.171-182
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• 2004

본 연구에서는 의료 영상과 유한요소 해석을 이용하여 골절된 척추체의 치료를 위해 골 시멘트를 주입하는 추체 성형술(vertebroplasty)에 영향을 미치는 여러 인자들에 대해 생체 역학적으로 분석하여 평가하고자 하였다. 의료 영상을 통해 구현된 모델들은 분석하고자 하는 인자에 대하여 크게 단분절과 다분절 유한요소 모델의 2 가지 형태로 구분하였다. 단분절 유한요소 모델을 통해 골다공증의 정도, 주입된 골 시멘트의 양, 골 시멘트의 주입량 및 환자에게 주입된 골 시멘트 양의 적절성을 평가하였으며, 골 시멘트의 주입이 척추체의 구조적 안정성에 미치는 효과를 분석하기 위하여 척추체 상종판에 수직 압축하중을 가하여 이때의 최대 수진 변위량을 분석하였다. 또한 단분절 척추체의 강성도(stiffness) 값을 산출한 뒤, 정상 상태의 척추체의 강성도 값으로 정규화 하였다. 다분절 유한요소 모델의 경우, 압박 골절 상태를 적용하여 척추 만곡의 변화가 인체에 미치는 영향을 분석하기 위하여 골절의 정도를 3 가지로 구현하였으며, 모델의 최상부에 압축 하중을 가한 후의 척추 만곡의 변화 정도를 분석하였다. 추체 성형술에 대한 다양한 인자들에 대한 분석 결과, 추체 성형술을 통해 환자의 골밀도가 상대적으로 높은 경우(BMD 50mg/$m\ell$이상)와 환자의 척추체 망상골 부피의 약 15%에 해당하는 골 시멘트 주입 시 가장 큰 척추체의 구조적 안정성의 증가 효과를 가져올 것으로 예측되었다. 또한 척추 골절이 미치는 영향에 대한 분석 결과, -2.8$^{\circ}$의 정상적인 후만곡을 가지는 T12∼L2 운동 분절이 골절의 모델링 후 약 9∼17$^{\circ}$의 큰 전만곡을 가지게 되었으며 이러한 척추 만곡의 변화는 동일한 하중 하에서 급격한 척추 만곡의 변화를 야기하는 것으로 나타났다. 또한 골절의 정도가 심할수록 척추 변형은 더욱 크게 증가하는 것으로 나타났다. 이러한 연구 결과들로부터, 전반적으로 추체 성형술은 골 시멘트의 주입량 또는 골밀도에 상관없이 약화된 척추체의 자체의 구조적 안정성의 증가 효과를 가져왔으며 골절로 인해 추체의 높이가 손상되었을 경우 이를 회복하는 것이 중요한 인자의 하나임을 나타내는 결과로 사료되어진다.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2004년도 추계학술대회 논문집
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• pp.1172-1175
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• 2004

At present, CHS(Compression Hip Screw) is one of the best prosthesis for the intertrochanteric fracture. There is nothing to evaluate the CHS itself with the finite element analysis and mechanical tests. They have same ways of the experimental test of the ASTM standards. The purpose of this study is to evaluate the existing CHS and the new CHS which have transformational design factors with finite element analysis and mechanical tests. The mechanical tests are divided into compression tests and fatigue test for evaluating the failure load, strength and fatigue life. This finite element method is same as the experimental test of the ASTM standards. Under 300N of compression load at the lag screw head. There are less differences between Group (5H, basic type) and Group which has 8 screw holes. However, there are lots of big differences between Group and Group which is reinforced about thickness of the neck range. Moreover, the comparison of Group and Group shows similar tendency of the comparison of Group and Group . The Group is reinforced the neck range from Group. After the experimental tests and the finite element analysis, the most effective design factor of the compression hip screws is the reinforcement of the thickness, even though, there are lots of design factors. Moreover, to unite the lag screw with the plate and to analyze by static analysis, the result of this method can be used with experimental test or instead of it.

• 한국운동역학회지
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• 제16권4호
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• pp.115-124
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• 2006

This study was conducted to investigate the running motion in the max-velocity phase(150-160m) and the fatigue phase(350-360m) during 400m sprint by performed elementary school athletes. Eighteen elementary school male athletes who achieved at least the 3rd place in the sprint at the Korea Gangwon-Do elementary school track and field meetings during 2004 and 2005 were selected as subjects. The running motions performed by the subjects were recorded using two 8mm high speed cameras at the nominal speed of 100 frames per second. The Direct Linear Transformation technique was adopted from the beginning of filming to the final stage of data extraction. KWON 3D motion analysis package program was used to compute the 3 Dimensional coordinates, smoothing factor in which lowpass filtering method was used and cutoff frequency was 6.0 Hz. The movement patterns during foot touchdown and takeoff for the running stride were related with the biomechanical consideration. Within the limitations of this study it is concluded: In order to increase running velocity, several conditions must be fullfilled at the instant of leg touchdown and takeoff during the fatigue phase(350-360m). First, the body C.O.G(Center of Gravity) height should be raised at the instant of leg touchdown and takeoff during the fatigue phase. Second, the foot contact time should be shortened and the takeoff distance should be increased at the foot takeoff during the fatigue phase. Third, the shank angular velocity with respect to a transverse axis through the center of gravity should be increased during the leg touchdown and takeoff in the fatigue phase. Forth, the active landing style described as clawing the ground with the sole of the foot should be performed during the leg touchdown and takeoff in the fatigue phase) phase. Fifth, In order to increase running velocity in the fatigue phase while taking a slightly greater leg knee angle and body lean angle within the range of the subject's running motion during the fatigue phase would result in greater flight distance.

• 대한치과교정학회지
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• 제31권4호
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• pp.415-424
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• 2001

교정치료에 있어서 anchorage는 진단 및 치료계획에서부터 치료 종료 단계까지 교정의사가 항상 염두에 두면서 치료를 진행 해야 하는 중요한 요소이다. 환자의 적극적인 협조를 필요로 하는 전통적인 anchorage 조절법 보다는 miniscrew 같은 skeletal anchorage 가 좀더 효과적인 방법으로 제시되어 지고 있어, miniscrew의 교정적 이용 시 고려사항에 대하여 전반적인 고찰과 증례보고를 통해서 niniscrew의 다양한 임상적 적용에 대해서 살펴보았다. 또한 midpalate부위가 miniscrew의 식립 부위로서 가지는 장점과 식립 시의 주의사항을 알아보았으며 skeletal anchorage 가 교정에 도입되면서 치료개념과 방법에 있어서의 변화를 요약하면 다음과 같다. 1. 절대적인 개념의 Anchorage가 도입 되었다. 2. 생역학적 면에서 치아의 치체이동이 쉬워지고 determinate system이 설계되어 질수 있다. 3. 기존의 수술로만 가능했던 치료들 중 일부는 교정 치료만으로 치료가 가능하게 되었다.

• 한국CDE학회논문집
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• 제17권3호
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• pp.149-155
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• 2012

The ankle over-pronation causes the mechanical overloading transferred to proximal areas (i.e. knees or hips) over time. Thus, the over-pronation is recognized as a contributory factor in a wide variety of musculo-skeletal pathologies in lower extremities. Commonly, over-pronated ankles are treated using specially designed insoles that support medial heels and correct the posture of lower limbs. However, the biomechanical effects of the insoles are not yet fully understood, so there still are controversies whether such insoles really have clinical significance. In this study, in order to verify the effects of insoles and determine the best shape of the insoles, we examined how the medio-lateral knee joint reaction force changes due to insole conditions through a case study about a subject. As a result, it is revealed that the medial heel post, which drastically reduced the peak medio-lateral knee joint reaction force, has significant effects on the gait of the over-pronated patients. However, in case that the arch support is combined together, the positive effect of the medial heel post may rather decrease.

• Journal of Korean Neurosurgical Society
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• 제46권4호
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• pp.328-332
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• 2009

Objective : The purpose of this study was to establish new fusion criteria to complement existing Brantigan-Steffee fusion criteria. The primary purpose of intervertebral cage placement is to create a proper biomechanical environment through successful fusion. The existence of a traction spur is an essential predictable radiologic factor which shows that there is instability of a fusion segment. We studied the relationship between the existence of a traction spur and fusion after a posterior lumbar interbody fusion (PLIF) procedure. Methods : This study was conducted using retrospective radiological findings from patients who underwent a PLIF procedure with the use of a cage without posterior fixation between 1993 and 1997 at a single institution. We enrolled 183 patients who were followed for a minimum of five years after the procedure, and used the Brantigan-Steffee classification to confirm the fusion. These criteria include a denser and more mature bone fusion area than originally achieved during surgery, no interspace between the cage and the vertebral body, and mature bony trabeculae bridging the fusion area. We also confirmed the existence of traction spurs on fusion segments and non-fusion segments. Results : The PLIF procedure was done on a total of 251 segments in 183 patients (71 men and 112 women). The average follow-up period was $80.4{\pm}12.7$ months. The mean age at the time of surgery was $48.3{\pm}11.3$ years (range, 25 to 84 years). Among the 251 segments, 213 segments (84.9%) were fused after five years. The remaining 38 segments (15.1%) were not fused. An analysis of the 38 segments that were not fused found traction spur formation in 20 of those segments (52.6%). No segments had traction spur formation with fusion. Conclusion : A new parameter should be added to the fusion criteria. These criteria should be referred to as 'no traction spur formation' and should be used to confirm fusion after a PLIF procedure.

• 융합정보논문지
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• 제10권4호
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• pp.160-167
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• 2020

본 연구는 달리기 시 속도와 경사변화가 하지관절의 생체역학적 요인에 미치는 영향을 보고자 한다. 이를 위해 20대 성인남성 15명이 트레드밀에서 2.7, 3.3 m/s와 -9°, -6°, 0°, 6°, 9°로 달리기를 실시하였고, 속도와 경사 변화에 따른 주행특성(보장, 보빈도), 생체역학적 변인(발목, 무릎, 엉덩관절의 가동범위, 모멘트, 관절파워), 지면반력(수직지면반력, 부하율, 제동력, 추진력)을 측정하였다. 연구결과, 주행특성은 오르막 달리기(UR)가 내리막 달리기(DR)에 비해 크게 나타났다(p<.05). 하지관절의 가동범위와 수직지면반력은 UR에서 크게 나타났고(p<.05), 하지관절의 모멘트와 제동력, 추진력, 부하율은 DR에서 크게 나타났다(p<.05). 관절파워는 발목관절은 DR에서 크고, 엉덩관절에서는 UR이 크게 나타났다(p<.05). 이러한 결과로부터 3.3m/s의 속도로 DR을 달리는 경우에서 발목관절 부상의 영향이 클 것으로 예상된다.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제28권6호
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• pp.456-463
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• 2002

Distraction osteogenesis is a well-established clinical treatment for limb length discrepancy and skeletal deformities. Appropriate mechanical tension-stress is believed not to break the callus but rather to stimulate osteogenesis. In contrast to fracture healing, the mode of bone formation in distraction osteogenesis is primarily intramembranous ossification. Although the biomechanical, histological, and ultrastructural changes associated with distraction osteogenesis have been widely described, the basic biology of the process is still not well known. Moreover, the molecular mechanisms in distraction osteogenesis remain largely unclear. Recent studies have implicated the growth factor cascade is likely to play an important role in distraction. And current reserch suggested that mechanical tension-stress modulates cell shape and phenotype, and stimulates the expression of the mRNA for bone matrix proteins. This article presents the hypotheses and current research that have furthered knowledge of the molecular biology that govern distraction osteogenesis. The gene regulation of growth factors and extracellular matrix proteins during distraction osteogenesis are discussed in this article. It is believed that understanding the biomolecular mechanisms that mediate distraction osteogenesis may guide the development of targeted strategies designed to improve distraction osteogenesis and accelerate bone healing.

• 한국운동역학회지
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• 제26권4호
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• pp.433-441
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• 2016

Objective: The purpose of this study was to understand the injury mechanism and to provide quantitative data to use in prevention or posture correction training by conducting kinematic and kinetic analyses of risk factors of lower extremity joint injury depending on the change of direction at different angles after a landing motion. Method: This study included 11 men in their twenties (age: $24.6{\pm}1.7years$, height: $176.6{\pm}4.4cm$, weight: $71.3{\pm}8.0kg$) who were right-leg dominant. By using seven infrared cameras (Oqus 300, Qualisys, Sweden), one force platform (AMTI, USA), and an accelerometer (Noraxon, USA), single-leg drop landing was performed at a height of 30 cm. The joint range of motion (ROM) of the lower extremity, peak joint moment, peak joint power, peak vertical ground reaction force (GRF), and peak vertical acceleration were measured. For statistical analysis, one-way repeated-measures analysis of variance was conducted at a significance level of ${\alpha}$ <.05. Results: Ankle and knee joint ROM in the sagittal plane significantly differed, respectively (F = 3.145, p = .024; F = 14.183, p = .000), depending on the change of direction. However, no significant differences were observed in the ROM of ankle and knee joint in the transverse plane. Significant differences in peak joint moment were also observed but no statistically significant differences were found in negative joint power between the conditions. Peak vertical GRF was high in landing (LAD) and after landing, left $45^{\circ}$ cutting (LLC), with a significant difference (F = 9.363, p = .000). The peak vertical acceleration was relatively high in LAD and LLC compared with other conditions, but the difference was not significant. Conclusion: We conclude that moving in the left direction may expose athletes to greater injury risk in terms of joint kinetics than moving in the right direction. However, further investigation of joint injury mechanisms in sports would be required to confirm these findings.

• Archives of Plastic Surgery
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• 제49권1호
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• pp.115-120
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• 2022

Background In addition to vascular endothelial cells, vascular smooth muscle cells (VSMCs) are subject to continuous shear stress because of blood circulation. The angiogenic properties of VSMCs in extracranial arteriovenous malformations (AVMs) may exceed those of normal blood vessels if the body responds more sensitively to mechanical stimuli. This study was performed to investigate the hypothesis that rapid angiogenesis may be achieved by mechanical shear stress. Methods VSMCs were obtained from six patients who had AVMs and six normal controls. The target genes were set to angiopoietin-2 (AGP2), aquaporin-1 (AQP1), and transforming growth factor-beta receptor 1 (TGFBR1). Reverse-transcriptase polymerase chain reaction (RT-PCR) and real-time PCR were implemented to identify the expression levels for target genes. Immunofluorescence was also conducted. Results Under the shear stress condition, mean relative quantity values of AGP2, AQP1, and TGFBR1 in AVM tissues were 1.927±0.528, 1.291±0.031, and 2.284±1.461 when compared with neutral conditions. The expression levels of all three genes in AVMs were higher than those in normal tissue except for AQP1 under shear stress conditions. Immunofluorescence also revealed increased staining of shear stress-induced genes in the normal tissue and in AVM tissue. Conclusions Shear stress made the VSMCs of AVMs more sensitive. Although the pathogenesis of AVMs remains unclear, our study showed that biomechanical stimulation imposed by shear stress may aggravate angiogenesis in AVMs.