• Title/Summary/Keyword: back-analyses

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Genome-wide association study identifies positional candidate genes affecting back fat thickness trait in pigs

  • Lee, Jae-Bong;Kang, Ho-Chan;Kim, Eun-Ho;Kim, Yoon-Joo;Yoo, Chae-Kyoung;Choi, Tae-Jeong;Lim, Hyun-Tae
    • Korean Journal of Agricultural Science
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    • v.45 no.4
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    • pp.707-713
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    • 2018
  • This study was done to search for positional candidate genes associated with the back fat thickness trait using a Genome-Wide Association Study (GWAS) in purebred Yorkshires (N = 1755). Genotype and phenotype analyses were done for 1,642 samples. As a result of the associations with back fat thickness using the Gemma program (ver. 0.93), when the genome-wide suggestive threshold was determined using the Bonferroni method ($p=1.61{\times}10^{-5}$), the single nucleotide polymorphism (SNP) markers with suggestive significance were identified in 1 SNP marker on chromosome 2 (MARC0053928; $p=3.65{\times}10^{-6}$), 2 SNP markers on chromosome 14 (ALGA0083078; $p=7.85{\times}10^{-6}$, INRA0048453; $p=1.27{\times}10^{-5}$), and 1 SNP marker on chromosome 18 (ALGA0120564; $p=1.44{\times}10^{-5}$). We could select positional candidate genes (KCNQ1, DOCK1, LOC106506151, and LOC110257583), located close to the SNP markers. Among these, we identified a potassium voltage-gated channel subfamily Q member gene (KCNQ1) and the dedicator of cytokinesis 1 (DOCK1) gene associated with obesity and Type-2 diabetes. The SNPs and haplotypes of the KCNQ1 and DOCK1 genes can contribute to understanding the genetic structure of back fat thickness. Additionally, it may provide basic data regarding marker assisted selection for a meat quality trait in pigs.

Design of the New Insecticidal Active Molecule against Diamond-Back Moth (Plutella Xylostella Linnaeus) (배추좀나방(Plutella Xylostella Linnaeus)에 대한 새로운 살충활성 분자의 설계)

  • Cho, Yun-Gi;Choi, Woo-Young;Sung, Nack-Do
    • Korean Journal of Agricultural Science
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    • v.34 no.2
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    • pp.171-179
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    • 2007
  • The new insecticidal active molecules from the based on the holographic quantitative structure-activity relationships (HQSAR) between a series of $1-(R_1)-2-(n-octyl)-3-(R_2)$, $3-(R_3)-pseudothiourea$ derivatives and their insecticidal activities against Diamond-back moth (Plutella Xylostella Linnaeus) were designed and discussed quantitatively. The most active molecule from the based graphical analyses of atomic contribution maps with the optimized HQSAR C-1 model ($q^2=0.764$ & $r^2{ncv}=0.942$) was 1-(n-butyl)-2-(t-butyl)-3,3-diisopropylpseudothiourea (P1: $pI_{50}=5.30$, $IC_{50}=1.397ppm$). Therefore, it is suggested that the new designed molecule would increased the activity as much as 23.5 times as compared to X=n-octyl substituent 17($pI_{50}=4.00$, $IC_{50}=32.86ppm$) which was the highest active molecule in training set compounds.

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A Study on the Length Variation of the Upper Body Surface according to Arm-movements for Early Elementary Schoolgirls (학령전기 여아의 상지동작에 따른 상반신 체표길이 변화 연구)

  • Pae Eun-Ah;Jang Jeong-Ah;Kwon Young-Suk
    • Journal of the Korean Society of Costume
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    • v.55 no.5 s.95
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    • pp.87-100
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    • 2005
  • This study was to provide the fundamental data for a scientific and rational clothing construction by investigating the length variation of the upper body surface, using the method of surgical tape. The subjects were 15 early elementary schoolgirls in Busan area classified by three somatotypes, Arm-movements were consisted of 6 types. The statistical analyses used in this study were mean, standard deviation and the ANOVA and LSD procedure. The results of the analysis of the length of the upper body surface are as follows: By arm-movements, in the items of horizontal, front neck base girth, back upper bust girth, back bust girth and back under bust girth were increased and the other standard lines were apt to be decreased. In the items of vertical, all standard lines of front side and side seam length showed increased, the lines of bark side were apt to be decreased. The shoulder length represented the maximum rate of decrease($-36.59\%{\~}-48.98\%$) in M6($180^{\circ}$) and the side seam showed the maximum rate of increase($49.74\%{\~}59.22\%$) in the same movement.

Fully Plastic Analyses of Unequally Notched Specimens in Bending Moment (굽힘 하중이 작용하는 비대칭노치시편의 완전소성해석)

  • Oh Chang-Kyun;Park Jin-Moo;Kim Yun-Jae
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.30 no.3 s.246
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    • pp.269-278
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    • 2006
  • This paper proposes slip line fields for bending of unequally notched specimens in plane strain that have a sharp crack in one side and a sharp V-notch in the other side. Depending on the back angle, two slip line fields are proposed, from which the limit moment and crack tip stress fields are obtained as a function of the back angle. Excellent agreement between slip line field solutions with those from detailed finite element limit analysis based on non-hardening plasticity provides confidence in the proposed slip line fields. One interesting point is that, for the unequally notched specimen, the difference between the crack tip triaxial stress for tension and that for bending increases significantly with increasing the back angle. This suggests that such a specimen could be potentially useful to investigate the crack tip constraint effect on fracture toughness of materials. In this respect, the possibility of designing a new toughness testing specimen with varying crack tip constraint is discussed.

Effects of taper and set-back on wind force and wind-induced response of tall buildings

  • Kim, Yongchul;Kanda, Jun
    • Wind and Structures
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    • v.13 no.6
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    • pp.499-517
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    • 2010
  • Advances in structural materials and construction methods have resulted in flexible and light tall buildings, making an assessment of structural safety during strong wind and serviceability/habitability during comparable medium/weak wind important design criteria. So far, lots of studies on suppressing the wind-induced responses have been carried out for tall buildings with aerodynamic modification. Most of the studies on aerodynamic modification have forced on the corner modification, while the studies on taper and set-back are limited. Changes of sectional shape through taper and set-back can modify the flow pattern around the models, encouraging more 3-dimensionalities, which results in reducing the wind-induced excitations. This paper discusses the characteristics of overturning moments and wind-induced responses of the tall buildings with height variations. The reduction of mean along-wind and fluctuating across-wind overturning moments are apparent in the suburban area than in urban area. A series of the response analyses, the rms displacement responses of the tall buildings with height variations are reduced greatly, while the rms acceleration responses are not necessarily reduced, showing dependences on wind direction.

Causes and Condition of Industrial Accidents during Manual Materials Handling (중량물 취급시 재해 발생 현황 몇 원인에 관한 연구)

  • 양성환
    • Journal of the Korean Professional Engineers Association
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    • v.30 no.5
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    • pp.96-104
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    • 1997
  • This study analyze industrial safety and health planning report for manufacture. The purpose of accident analysis is to obtain accurate and objective information about the causes of accidents in order to prevent accidents from reoccurring. This study investigated the causes and conditions of occupational accidents in Korean industry. As the most accidents are occurred in lifting material, the questionnaire analyses about injuries are operated for occur to deal with the Manual Materials Handing. The results show that there are some characteristics in the accidents of Korean industry since 1986: (1) accidents rates tend to have lower since 1983(1994-1.18%, 1995-0.99%, 1996-0.88%), (2) larger companies tend to have lower accident rates than the smaller ones, (3) inexperience is related to high accident rates(1995-51.26%, 1996-48.82%1, because of the careless education for freshman such as OJT which in order to prevent accident, and (4) the body sites most vulnerable to injury are the hands and fingers and increased the back(caused of Back pain). The results of questionnaire analysis show that operator(n= 104) interested in reinforce the back & belly(42.86%). These finding identified in this study can be used to prevent the industrial accidents, and used to improving directions based on analyzed result.

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Facilitation of the four-mask process by the double-layered Ti/Si barrier metal for oxide semiconductor TFTs

  • Hino, Aya;Maeda, Takeaki;Morita, Shinya;Kugimiya, Toshihiro
    • Journal of Information Display
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    • v.13 no.2
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    • pp.61-66
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    • 2012
  • The double-layered Ti/Si barrier metal is demonstrated for the source/drain Cu interconnections in oxide semiconductor thin-film transistors (TFTs). The transmission electromicroscopy and ion mass spectroscopy analyses revealed that the double-layered barrier structure suppresses the interfacial reaction and the interdiffusion at the interface after thermal annealing at $350^{\circ}C$. The underlying Si layer was found to be very useful for the etch stopper during wet etching for the Cu/Ti layers. The oxide TFTs with a double-layered Ti/Si barrier metal possess excellent TFT characteristics. It is concluded that the present barrier structure facilitates the back-channel-etch-type TFT process in the mass production line, where the four- or five-mask process is used.

Power Flow Control of a Multi-bus/Three-feeder Distribution System Using Generalized Unified Power Quality Conditioner

  • Mohammed, B.S.;Ibrahim, R.;Perumal, N.;Rao, K.S. Rama
    • Journal of Electrical Engineering and Technology
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    • v.10 no.1
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    • pp.8-17
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    • 2015
  • This paper analyses the power flow of a three-feeder/multi-bus distribution system by a custom Generalized Power Quality Conditioner (GUPQC). The GUPQC has been realized by three voltage source converters (VSCs) coupled back-to-back through a common DC-link capacitor on the DC-side. One feeder was controlled by the shunt compensator, whereas each of the other two feeders was controlled by the proposed novel series compensator. The GUPQC has the capability to simultaneously compensate voltage and current quality problems of a multi-bus/three-feeder distribution system. Besides that, the power can be transferred from one feeder to other feeders to compensate for poor power quality problems. Extensive simulation studies were carried out by using MATLAB/SIMULINK software to establish the ability of the GUPQC to improve power quality of the distribution systems under distorted supply voltage conditions.

Development of the Slim-fit Formal Pants Pattern for Middle-aged Men (중년 남성 정장 슬림 핏 팬츠 패턴 개발에 관한 연구)

  • Yang, Chung-Eun
    • Journal of the Korean Society of Clothing and Textiles
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    • v.35 no.1
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    • pp.26-36
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    • 2011
  • The study analyzes the development of slim-fit formal pants patterns for middle-aged men. This study suggests a new pattern that complements the problems of the existing fit on the basis of the standard nude size for middle-aged men with lower garments through the analyses of one-tuck pants patterns from 5 popular brands. As a result, the waistline is lowered by 0.8cm out of consideration for the waist circumference. The crotch extension is reduced by 1.5cm, the back crotch length is revised, the center back waist point is raised by 0.9cm, and the hip line is straightened. The slim-fit is perfected of the new lines from the thigh to knee-line.

Parameter Extraction of DQ-Axis Inductance and Back-EMF Constant For IPM Type Motors Based on Nonlinear Finite Element Analysis (비선형 효과를 고려한 IPM형 전동기의 DQ축 인덕턴스 및 역기전력상수 파라미터 추출)

  • Choi, Hong-Soon
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.56 no.3
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    • pp.519-523
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    • 2007
  • In this paper, we propose a precise parameter extraction of interior permanent magnet (IPM) motors based on finite element analysis. For the calculation of the two-axis inductances Ld and Lq, the slotting effect and cross magnetization due to torque angle are considered. It is examined that back electro-motive force (BEMF) constant is affected by the magnetic saturation in different ways dependent on motor types. Numerical analyses and some measurements are performed for a spoke type and a flux barrier type IPM motors