• 대한기계학회:학술대회논문집
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• 대한기계학회 2003년도 춘계학술대회
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• pp.201-206
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• 2003

This study is test for STS304 specimen using bending and torsion state. Rounded specimen and notched specimen including fracture surface investigation was comparatively experimented, fatigue life according to degree of surface finishing was examined. Fatigue fracture probability of notched canilever specimens were predicted by P-S-N curve, median rank and Weibull distribution. And at the relation with the rotational speed and stress, the fatigue life of the test specimen was higher at high speed than low speed If summarize STS304 torsion result of fatigue test, is as following. Fatigue life prediction was available by Weibull statistics distribution, and 50% breakdown probability correlation equation was appeared as following.

• Journal of Biosystems Engineering
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• 제41권3호
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• pp.240-254
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• 2016

Background: Foodborne pathogens are a growing concern with respect to human illnesses and death. There is an increasing demand for improvements in global food safety. However, it is a challenge to detect and identify these harmful organisms in a rapid, responsive, suitable, and effective way. Results: Rapid developments in biosensor designs have contributed to the detection of foodborne pathogens and other microorganisms. Biosensors can automate this process and have the potential to enable fast analyses that are cost and time-effective. Various biosensor techniques are available that can identify foodborne pathogens and other health hazards. Conclusions: In this review, biosensor technology is briefly discussed, followed by a summary of foodborne pathogen detection using various transduction systems that exhibit specificity for particular foodborne pathogens. In addition, the recent application of biosensor technology to detect pesticides and heavy metals is briefly addressed.

• 한국정밀공학회지
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• 제15권8호
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• pp.33-38
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• 1998

TiYN coated high speed steel tools have been developed and their tool lifes were assessed. First yttrium alloyed titanium target was manufactured, then using the arc ion plating(AIP) technique TiYN coating was deposited onto high speed steel substrate. Three kinds of varying thickness of TiYN coated tools were prepared. Cutting tests were carried out with theses tools and for comparison with the commercially available uncoated, TiN, TiCN and TiAlN coated tools. During the cutting tests flank wear width vs. cutting time was measured. It has been revealed that the newly developed TiYN coated tools show superior tool life characteristics to others.

• 품질경영학회지
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• 제41권3호
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• pp.413-421
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• 2013

Purpose: System availability and life cycle cost are often used to evaluate the system performance and is influenced by the operation and maintenance characteristic. In this paper, we propose the method to improve life cycle cost and satisfy the target availability through redundancy allocation. Methods: We consider the redundancy is available at all items in multi level system. Thus, we assume that sub-assembly, module, components can be duplicated. Simulation and genetic algorithm are employed to optimize redundancy allocation. Results: Target availability is higher, the life cycle cost is increased. In addition, the items for redundancy are selected at higher level in multi level system if target availability is higher. Conclusion: We could know that target availability affects the duplication number of items and the selection of redundancy items. For further study, we will consider new optimization algorithms to compare with the proposed GA algorithm and improve optimization performance.

• Tribology and Lubricants
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• 제15권2호
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• pp.150-155
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• 1999

The rolling fatigue lives (RFL) of five kinds of silicon nitride balls were investigated. Four kinds of Si$_3$N$_4$balls were fabricated using different raw materials, sintering aids and sintering conditions. Commercially available Si$_3$N$_4$ball was also studied for comparison. All the balls were finished up to the dimensional accuracy of Grade 10 defined in KS B 2001 (Steel Balls fer Ball Bearings) with a size of 9.525 mm. RFL tests were then conducted under the initial theoretical maximum contact stress 6.38 GPa and the spindle speed 10,000 rpm. Gear oil was provided by oiled race as lubricant. The results of RFL test indicated the prerequisitic conditions for the long rolling life of Si$_3$N$_4$ball : (1) the high density, (2) microstructures consisted of small uniformly distributed grains, (3) little glassy phase in grainboundary, and (4) little crystalline phase and secondary phase that induces residual thermal stress due to the differences of thermal expansion coefficient with Si$_3$N$_4$phase.

• Bulletin of the Korean Chemical Society
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• 제32권1호
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• pp.175-178
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• 2011

A facile, convenient, efficient and high yielding synthesis of a combinatorial library of coumarins has been developed by the condensation of readily available $\beta$-oxodithioesters and S,S-acetal with 2-hydroxy-1-naphthaldehyde in the presence of catalytic amount of $CuCl_2$ under solvent free conditions.

• BMB Reports
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• 제53권1호
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• pp.3-9
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• 2020

The mitochondrial genome encodes 13 proteins that are components of the oxidative phosphorylation system (OXPHOS), suggesting that precise regulation of these genes is crucial for maintaining OXPHOS functions, including ATP production, calcium buffering, cell signaling, ROS production, and apoptosis. Furthermore, heteroplasmy or mis-regulation of gene expression in mitochondria frequently is associated with human mitochondrial diseases. Thus, various approaches have been developed to investigate the roles of genes encoded by the mitochondrial genome. In this review, we will discuss a wide range of techniques available for investigating the mitochondrial genome, mitochondrial transcription, and mitochondrial translation, which provide a useful guide to understanding mitochondrial gene expression.

• International Journal of Reliability and Applications
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• 제4권2호
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• pp.57-69
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• 2003

A non-parametric test based on U-statistic for testing exponentiality against the new better than used renewal failure rate (NBURFR) alternatives is introduced and the percentiles of this test statistic are tabulated for sample size 5(1)50. Its properties are also discussed including the Pitman asymptotic efficiency relative to the tests of the new better than used and new better than used failure rate (Ahmed (1994) and Hendi (2000)). The powers of this test are also calculated for some used life distributions. An example from blood cancer patients demonstrates a practical application of our test in the medical sciences is presented. Finally the problem when right-censored data is available is handled.

• 한국산학기술학회논문지
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• 제5권4호
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• pp.286-291
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• 2004

실무 현장에서 피로 파괴가 잘 일어나고 있는 상황이다. 그런데 그 하중도 불규칙적으로 일어나고 있어 예측이 불가능하여 언제 파괴가 일어나는지를 잘 알 수가 없는 상황이다. 본 연구에서는 그러한 불규칙적인 피로 하중을 시뮬레이션 하여 그 재료의 안정성과 수명 관계를 Ansys workbench 프로그램을 이용하여 이론적으로 해석하여 보았다. 이러한 결과들을 실제 구조물에서 응용하면 그 파손 방지 및 내구성을 예측하는데 활용이 크다고 본다.

• Journal of Ginseng Research
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• 제47권5호
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• pp.622-626
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• 2023

The COVID-19 pandemic has changed the world and has presented the scientific community with unprecedented challenges. Infection is associated with overproduction of proinflammatory cytokines secondary to hyperactivation of the innate immune response, inducing a cytokine storm and triggering multiorgan failure and significant morbidity/mortality. No specific treatment is yet available. For thousands of years, Panax notoginseng has been used to treat various infectious diseases. Experimental evidence of P. notoginseng utility in terms of alleviating the cytokine storm, especially the cascade, and improving post-COVID-19 symptoms, suggests that P. notoginseng may serve as a valuable adjunct treatment for COVID-19 infection.