• 한국전자파학회논문지
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• 제22권3호
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• pp.299-311
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• 2011

본 논문에서는 펄스 체이싱 스캔 방식을 이용한 바이스태틱 MTI 레이더 시스템에서 시스템 불안정 요인들을 식별하고 MTI 개선 성능에 미치는 영향에 대해 고찰하였다. 펄스 체이싱 스캔 방법은 송신 펄스 단위로 제한된 영역을 탐지하는 스캔 방법이며, MTI 필터는 작은 수의 펄스를 이용하여 클러터와 같은 간섭으로부터 표적을 분리할 수 있는 신호 처리 방법이다. 이상적인 MTI 신호 처리 과정은 클러터 자체의 특성에 의해서 클러터 감쇄 및 시스템 개선 성능이 제한되나, 제안된 바이스태틱 레이더 구조에서 MTI 성능은 펄스 체이싱 스캔 동안 수신빔 조향 오차에 의해 영향을 받을 수 있다. 또한, 바이스태틱 수신기에서 시간 동기 오차, COHO의 위상 오차 및 주파수/위상 동기 오차로부터 야기된 다른 시스템 불안정 요소들을 정의하고, 시스템 성능 개선에 미치는 영향들을 분석하였다.

• 전기학회논문지
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• 제66권12호
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• pp.1844-1851
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• 2017

As the capacity of the wireless power transmission increases, a higher supply current which may induce current in nearby conductive parts requires. Induced current may affect electric shock to the human body and malfunction of the electrical equipment. In order to prevent such induced phenomena as a risk factor, shielding is required between the source of the wireless power transmission and the conductive parts. The resonance frequency for the large capacity wireless power transmission has the wavelength of several hundred meters, so most environments are included in the near-field area. By wave impedance, the electric field has higher density in the near-field area and needs to be analyze for protecting. For this purpose, it is necessary to select a substance having a larger electric conductivity and optimized shielding structure. In this paper, an aluminum base shielding structure was presented to conduct experiments on thickness, position, and heat dissipation. In the 35 kW, 60 kHz environments, the optimized 5T Al base shielding structure attenuates the induced current to 43 %.

• Journal of Microbiology and Biotechnology
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• 제29권5호
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• pp.820-826
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• 2019

This study evaluated the anti-inflammatory potential of a grasshopper ketone (GK) isolated from the brown alga Sargassum fulvellum on lipopolysaccharide (LPS)-induced RAW 264.7 murine macrophage cell line. GK was isolated and purified from the n-hexane fraction and its structure was verified on the basis of NMR spectroscopic data. GK up to $100{\mu}g/ml$ is not cytotoxic to RAW 264.7, and is an effective inhibitor of LPS-induced NO production in RAW 264.7 cells. The production of pro-inflammatory cytokines, including IL-6, $IL-1{\beta}$, and $TNF-{\alpha}$ was found significantly reduced in $0.1-100{\mu}g/ml$ dose ranges of GK treatment (p < 0.05). We confirmed the dose-dependent and significant inhibition of iNOS and COX-2 proteins expression. In addition, it has been shown that GK induces anti-inflammatory effects by inhibiting MAPKs (ERK, JNK, and p38) and $NF-{\kappa}B$ p65 phosphorylation. Our results show that the anti-inflammatory properties of GK may be due to the inhibition of the $NF-{\kappa}B$ and MAPKs pathways, which are associated with the attenuation of cytokine secretion.

• Nuclear Engineering and Technology
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• 제53권1호
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• pp.282-293
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• 2021

This paper examines gamma-ray shielding properties of SBC-Bx glass system with the chemical composition of 40SiO₂-10B₂O₃-xBaO-(45-x)CaO- yZnO- zMgO (where x = 0, 10, 20, 30, and 35 mol% and y = z = 6 mol%). Mass attenuation coefficient (µ/ρ) which is an essential parameter to study gamma-ray shielding properties was obtained in the photon energy range of 0.015-15 MeV using PHITS Monte Carlo code for the proposed glasses. The obtained results were compared with those calculated by WinXCOM program. Both the values of PHITS code and WinXCOM program were observed in very good agreement. The (µ/ρ values were then used to derive mean free path (MFP), electron density (N_eff), effective atomic number (Z_eff), and half value layer (HVL) for all the glasses involved. Additionally, G-P method was employed to estimate exposure buildup factor (EBF) for each glass in the energy range of 0.015-15 MeV up to penetration depths of 40 mfp. The results reveal that gamma-ray shielding effectiveness of the SBC-Bx glasses evolves with increasing BaO content in the glass sample. Such that SBC-B35 glass has superior shielding capacity against gamma-rays among the studied glasses. Gamma-ray shielding properties of SBC-B35 glass were compared with different conventional shielding materials, commercial glasses, and newly developed HMO glasse. Therefore, the investigated glasses have potential uses in gamma shielding applications.

• Nuclear Engineering and Technology
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• 제53권3호
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• pp.949-959
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• 2021

The current study aims to explore the shielding properties of multi-component borate-based glass series. Seven glass-samples with composition of (80-y)H₃BO₃-10ZnO-10Na₂O-yBaO where (y = 0, 5, 10, 15, 20, 25 and 30 mol.%) were synthesized by melt-quench method. Various shielding features for photons, neutrons, and protons were determined for all prepared samples. XCOM, Phy-X program, and SRIM code were performed to determine and explain several shielding properties such as equivalent atomic number, exposure build-up factor, specific gamma-ray constants, effective removal cross-section (Σ_R), neutron scattering and absorption, Mass Stopping Power (MSP) and projected range. The energy ranges for photons and protons were 0.015-15 MeV and 0.01-10 MeV, respectively. The mass attenuation coefficient (μ/ρ) was also determined experimentally by utilizing two radioactive sources (¹⁶⁶Ho and ¹³⁷Cs). Consistent results were obtained between experimental and XCOM values in determining μ/ρ of the new glasses. The addition of BaO to the glass matrix led to enhance the μ/ρ and specific gamma-ray constants of glasses. Whereas the remarkable reductions in Σ_R, MSP, and projected range values were reported with increasing BaO concentrations. The acquired results nominate the use of these glasses in different radiation shielding purposes.

• Journal of the Korean Physical Society
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• 제73권9호
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• pp.1377-1384
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• 2018

Accurate measurement of the absorbed dose and the effective dose is required in dental panoramic radiography involving relatively low energy with a rotational X-ray tube system using long exposures. To determine the effectiveness of measuring the irradiation by using passive dosimetry, we compared the entrance skin doses by using a radiophotoluminescent glass dosimeter (RPL) and an optically stimulated luminescence detector (OSL) in a phantom model consisting of nine and 31 transverse sections. The parameters of the panoramic device were set to 80 kV, 4 mA, and 12 s in the standard program mode. The X-ray spectrum was applied in the same manner as the panoramic dose by using the SpekCalc Software. The results indicated a mass attenuation coefficient of $0.008226cm^2/g$, and an effective energy of 34 keV. The equivalent dose between the RPL and the OSL was calculated based on a product of the absorbed doses. The density of the aluminum attenuators was $2.699g/cm^3$. During the panoramic examination, tissue absorption doses with regard to the RPL were a surface dose of $75.33{\mu}Gy$ and a depth dose of $71.77{\mu}Gy$, those with regard to the OSL were surface dose of $9.2{\mu}Gy$ a depth dose of $70.39{\mu}Gy$ and a mean dose of $74.79{\mu}Gy$. The effective dose based on the International Commission on Radiological Protection Publication 103 tissue weighting factor for the RPL were $0.742{\mu}Sv$, $8.9{\mu}Sv$, $2.96{\mu}Sv$ and those for the OSL were $0.754{\mu}Sv$, $9.05{\mu}Sv$, and $3.018{\mu}Sv$ in the parotid and sublingual glands, orbit, and thyroid gland, respectively. The RPL was more effective than the OSL for measuring the absorbed radiation dose in low-energy systems with a rotational X-ray tube.

• Biomolecules & Therapeutics
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• 제31권2호
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• pp.161-167
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• 2023

Despite the various medications used in clinics, the efforts to develop more effective treatments for depression continue to increase in the past decades mainly because of the treatment-resistant population, and the testing of several hypotheses- and target-based treatments. Undesirable side effects and unresponsiveness to current medications fuel the drive to solve this top global health problem. In this study, we focused on neuroinflammatory response-mediated depression which represents a cluster of depression etiology both in animal models and humans. Several meta-analyses reported that proinflammatory cytokines such as interleukin 6 (IL-6) and tumor necrosis factor-α (TNF-α) were increased in major depressive disorder patients. Inflammatory mediators implicated in depression include type-I interferon and inflammasome pathways. To elucidate the molecular mechanisms of neuroinflammatory cascades underlying the pathophysiology of depression, we introduced hycanthone, an antischistosomal drug, to check whether it can counteract depressive-like behaviors in vivo and normalize the inflammation-induced changes in vitro. Lipopolysaccharide (LPS) treatment increased proinflammatory cytokine expression in the murine microglial cells as well as the stimulation of type I interferon-related pathways that are directly or indirectly regulated by Janus kinase-signal transducer and activator of transcription (JAK-STAT) activation. Hycanthone treatment attenuated those changes possibly by inhibiting the JAK-STAT pathway and inflammasome activation. Hycanthone also ameliorated depressive-like behaviors by LPS. Taken together, we suggest that the inhibitory action of hycanthone against the interferon pathway leading to attenuation of depressive-like behaviors can be a novel therapeutic mechanism for treating depression.

• Nuclear Engineering and Technology
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• 제55권1호
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• pp.278-284
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• 2023

The synthetic B₂O₃-As₂O₃ glass ceramic are prepared to investigate the physical properties and the radiation shielding capabilities with the variation of concentration of the As₂O₃ with 10, 20, 30, and 40%, respectively. XRD analyses are performed on the fabricated glass-ceramic and depicted the improvement of crystallinity by adding As₂O₃. The radiation shielding properties are studied for the B₂O₃-As₂O₃ glass ceramic. The values of linear attenuation coefficient (LAC) are varied with the variation of incident photon gamma energy (23.1-103 keV). The LAC values enhanced from 12.19 cm^-1-37.75 cm^-1 by raising the As₂O₃ concentration from 10 to 40 mol% at low gamma energy (23.1 keV) for BAs10 and BAs40, respectively. Among the shielding parameters, the half-value layer, transmission factor, and radiation protection efficiency are estimated. Furthermore, the fabricated samples of glass ceramic have low manufacturing costs and good shielding features compared to the previous work. It can be concluded the B₂O₃-As₂O₃ glass ceramic is appropriate to apply in X-ray or low-energy gamma-ray shielding applications.

• 전기전자학회논문지
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• 제26권1호
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• pp.89-94
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• 2022

W-대역(75-110GHz)은 기존 5G 대역에 비해 최소 10배 이상의 대역폭 활용이 가능한 대역이다. 따라서 가상 및 증강 현실과 같이 빠른 속도와 저지연이 요구되는 미래 이동통신에 적합한 대역 중 하나이다. 그러나 파장이 짧아 높은 경로손실을 가지며, 대기환경에도 매우 민감한 특성을 가진다. 따라서 향후 W-대역 통신 시스템 개발을 위해서는, 채널 환경에 따른 경로손실의 특성을 분석할 필요가 있다. 본 논문에서는 W-대역 경로손실의 특성을 분석하기 위해 랜덤 포레스트 기법을 이용, 다양한 채널 환경 파라미터에 따른 경로손실 데이터를 통해 거리 구간에 따른 채널 파라미터의 영향성을 분석하였다. 시뮬레이션 결과, 근거리에서의 경로손실은 거리가 가장 높은 영향성을 가지며, 채널 환경 요소는 거의 무시된다. 그러나 거리 구간이 길어질수록 거리의 영향성이 감소하는 동시에 클러터와 강우량의 영향성이 증가하였다.

• Radiation Oncology Journal
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• 제9권1호
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• pp.131-141
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• 1991

국내에서 처음으로 사용되는 CLINAC 1800에서 발생된 15MV X-선의 특성을 구하기 위하여 3 Dimensional water Phantom Dosimetry system)를 이용하여 방사선 치료에 근간이 되는 심부선량 백분율(POD), 최대 조직 비율(TMR), 편평도(beam profile), 대칭도, Wedge인자 등을 측정하였고 선량계산을 위하여 출력 인자들을 구하였다. 1. 선축상 최대치 지점(Dmax)은 SSD 100cm일때 조사면이 $10\times10cm^2$에서 $3.0\pm0.1$ cm이였고 $4\times4cm^2,\;35\times35cm^2$에서 각각 $3.1\pm0.1\;cm,2.2\pm0.1$ cm으로 조사면이 넓어지면서 측정치가 표면에 가까워지는 결과를 보였다. 2. 조직표면 선량(Surface Dose)는 SSD 100cm일때 조사면이 $10\times10cm^2$에서 $15.5\%$이였고 $4\times4cm^2,\;35\times35cm^2$에서 각각 $9.8\%\;,51.2\%$로 조사면이 넓어지면서 표면 선량은 증가하는 결과를 보였다. 3. 심부선량 백분율(PDO)은 SSD 100cm에서 측정하였고 조사면이 $10\times10cm^2$이고 10cm depth에서 $76.8\%$이였고 $80\%,\;50\%$ 선량의 깊이는 각각 $9.1\pm0.1\;cm,19.9\pm0.2\;cm$으로 측정되었다. 4. 최대조직비율(TMR)은 심부선량 백분율(PDD)로부터 계산하였고 측정값과의 차이는 $10\times10cm^2$ 조사면에서 평균 $1\;%$ 이내의 오차를 보였다. 5. 대칭도(symmetry)와 편평도(flatness)는 조사면 $10\times10cm^2$일때 각각 $0.73\%,\;2.72\%$이였다. 6. 출력인자(output factor)는 $10\times10cm^2$ 기준 조사면에서 흡수선량을 1로 하였을때 $4\times4cm^2,\;35\times35cm^2$ 조사면에서는 각각 0.927, 1.087로 측정되었는데 조사면이 증가할수록 흡수량이 증가하는 결과를 보였다. 7. Wedge factor는 $15^{\circ}\;30^{\circ}\;45^{\circ}\;60^{\circ}$를 10cm깊이에서 측정하였는데 0.825, 0.099, 0.560, 0.457로 각각 측정되었고 아크릴 0.4 mm Tray의 투과율은 0.976이였다. 8. 15 MV X-선에 의한 납벽층의 반가층 두께는 13 mm였고 Cerrobend의 반가층은 15.5 mm으로 측정되었다.