• Title/Summary/Keyword: atrophic rhinitis

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Stellate Ganglion Blocks in Atrophic Rhinitis (위축성 비염 환자에서 성상신경절 블록의 치료효과 -증례 보고-)

  • Kim, Seung-Jun;Lee, Woo-Chang;Chang, Won-Sok;Yoon, Duck-Mi
    • The Korean Journal of Pain
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    • v.14 no.2
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    • pp.231-233
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    • 2001
  • Atrophic rhinitis is characterized by mucosal atrophy, bony absorption, persistent fetid odor and resistance to medical and surgical treatment. Stellate ganglion block (SGB) can be used as a therapeutic modality by improving the regional blood flow through sympathetic blockade. We present a case of a 57 year-old male patient who had been treated unsuccessully for atrophic rhinitis for several years by surgical and conservative measures. The patient presented at our pain clinic with shoulder pain and received stellate ganglion block once or twice a week. He received more than 75 SGBs in addition to the routine conservative treatment for atrophic rhinitis. As the number of blocks performed increased, the patient demonstrated subjective symptom relief. We measured regional mucosal blood flow using a laser doppler flowmeter after the 28th, 63rd and 75th blocks. Nasal mucosal blood flow was improved by 4.9%, 28.8% and 36.3% respectively. We also were able to observe the recovery of mucosal atrophy to an almost normal level by nasal endoscopy. The patient is currently free of symptoms and is being followed up on an outpatient bases.

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Clinical and bacteriological studies on infectious atrophic rhinitis of swine (돼지 전염성 위축성 비염의 임상학적 및 세균학적 연구)

  • Kim, Bong-hwan;Tak, Ryun-bin;Cho, Gil-jae;Jang, Hee-kyung
    • Korean Journal of Veterinary Research
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    • v.31 no.4
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    • pp.457-469
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    • 1991
  • Clinical and bacteriological observations on infectious atrophic rhinitis of swine were conducted in order to obtain some basic information for the clinical and immnnological control of the disease prevailing in the republic. Samples were collected from nasal cavities of 135 4~12 week old pigs from 12 herds and from turbinates of 199 slaughtering pigs from 14 swine herds to investigate the prevalence of Bordetella bronchiseptica and/or Pasteurella multocida in the nasal cavities of the pigs. On the examination of nasal swabs by cultural techniques and of gross lesion of snouts of slaughtering pigs, all the swine herds investigated were found to be affected by atrophic rhinitis and a total of 84 B bronchiseptica and 139 P multocida cultures were isolated from the nasal cavities of the pigs. Of the 199 slaughtering pigs, some 48% revealed gross pathological lesion typical of atrophic rhinitis and the prevalence of B bronchiseptica and P multocida were 27.6% and 46.7%, respectively. Biochemical properties, antimicrobial susceptibilities, serological characteristics and toxigenicity of the isolates of B bronchiseptica and P multocida were investigated.

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A Case Report of a Feral Pig with Suspected Infectious Atrophic Rhinitis Lesions (야생 멧돼지의 전염성위축성비염 소견의 1예)

  • 곽수동;김종섭;연성찬;김용환;서명득;고필옥
    • Journal of Veterinary Clinics
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    • v.18 no.2
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    • pp.185-188
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    • 2001
  • A weakened wild feral pig (a boar of about 15 kg) with snout distortion and characteristic external lesion of infectious atrophic rhinitis was captured at farm land near low mountains in Chinju, Kyeongnam province. This pig was necropsied and then the snout parts and the parenchymal organs were removed. The snout and nose were transversely sectioned at thickness of 1.5 cm interval. Grossly, the right side of the snout was shorted than that of left by reduction of right nasal turbinate length, but the nasal opening exudate was not observed. At necropsy, degeneration, adhesion, occlusion, and asymmetry of left and right sides on the meatus and turbinate were observed and findings of mild pneumonia were observed. Microscopically, the leukocyte infiltration, hyperemia and hyperplasia on the mucosa of the turbinates and septum were observed. The atrophied periosteum and osseous tissue were also observed. But Bordetella bronchiseptica was not identified in culture from nasal swabs. We expect the possibility that the snout distortion of this pig was due to infectious atrophic rhinitis according to these findings.

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Control of endemic diseases in breeding pigs by means of slaughter check (Slaughter check에 의한 종돈의 방역관리)

  • Kim, Bong-Hwan;Choo, Ji-Hoon;Cho, Kwang-Hyun;Park, Choi-Kyu;Jung, Byeong-Yeal
    • Korean Journal of Veterinary Research
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    • v.46 no.1
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    • pp.27-34
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    • 2006
  • This paper describes the slaughter check results of breeding pigs from the Korean Swine Testing Station for the control of endemic diseases. Gross lesions monitored in the present study included those conditions commonly associated with economically significant subclinical herd infections: enzootic pneumonia, pleuropneumonia, pleuritis, atrophic rhinitis, liver white spots, papular dermatitis and ileitis. A total of 128 slaughter pigs were investigated at 4 subsequent tests according to the slaughter check procedures established. The prevalence of enzootic pneumonia, pleuropneumonia and pleuritis in the initial test was 67.9%, 28.6% and 17.9%, respectively. However, these were decreased to 46.7%, 6.7% and 6.7%, respectively, in the last test after implementation of counter measures including clean-up protocols and medication programs (p > 0.05). The mean pneumonic score also significantly decreased from 6.8 in the initial test to 2.8 in the last test. The prevalence of atrophic rhinitis (${\geq}score\;2$) was 32.2% and mean atrophic rhinitis score of 1.1 were recorded. However, no significant improvement of conditions was achieved with the counter measures indicating that atrophic rhinitis was originated from the source herds and lesions developed early in the life. In the initial test, prevalence of liver white spots and papular dermatitis lesions was 21.4% and 25.0%, respectively. These conditions were cleaned by the implementation of parasite control measures with all-in all-out, strict clean-up protocols and proper medications adopted in the present study (liver white spots, p = 0.0124; papular dermatitis lesions, p = 0.0055). The prevalence of ileitis lesions in slaughter pigs from the initial test was 28.6%, it could be gradually reduced by the use of repeated treatments and control measures but the effect was not so significant (p > 0.05). In conclusion, slaughter check procedures were successfully established and applied for the control of endemic diseases in the Korean Swine Testing Station.

Immunogenicity of the recombinant Pasteurella multocida toxin for development of subunit vaccine against swine atrophic rhinitis (돼지 위축성 비염 단위 백신 개발을 위한 재조합 파스튜렐라 독소 단백질의 면역원성 검정)

  • Lee, Jeongmin
    • Korean Journal of Veterinary Research
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    • v.47 no.1
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    • pp.59-65
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    • 2007
  • Pasteurella multocida Pasteurella multocida toxin (PMT) is a causal pathogenin atrophic rhinitis in pigs. To investigate the protective immunity and vaccination effect of recombinantPMT, the gene for PMT was isolated from the infective P. multocida D:4. The 2.3 kb XhoI/PstI fragment(PMT2.3) of PMT gene was expressed in E. coli BL21 (DE3) using the induced expression vector system.The recombinant protein of PMT2.3 having molecular weight of 84 kDa was purified by Ni-afinitycolumn chromatography. The PMT2.3 raised slightly less anti-PMT antibody titer than formalin-killedwhole cel, however, it showed more protective imunity against P. multocida D:4 infection in vaccinationand chalenge.

Molecular Cloning and Characterization of the Gene for Outer Membrane Protein H in a Pasteurella multocida (D:4) Isolate from Pigs with Atrophic Rhinitis Symptoms in Korea

  • LEE, JEONG-MIN;KANG, SEO-YOUNG;PARK, SHIN-IN;WOO, HEE-JONG;KWON, MOO-SIK
    • Journal of Microbiology and Biotechnology
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    • v.14 no.6
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    • pp.1343-1349
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    • 2004
  • A native strain of Pasteurella multocida was isolated from pigs suffering from severe atrophic rhinitis at domestic farms in Gyeonggi Province, Korea, and was identified as capsular serogroup 'D' and somatic serotype '4' by disc diffusion decapsulation and gel diffusion precipitation tests, respectively. The P. multocida (D:4) induced atrophic rhinitis in healthy pigs by the secondary infection. The gene for outer membrane protein H (ompH) of P. multocida (D:4) was cloned in Escherichia coli DH5$\alpha$ by PCR. The open reading frame of the ompH was composed of 1,023 bp, possibly encoding a protein with 341 amino acid residues containing a signal peptide of 20 amino acids at N-terminus, and the gene product with molecular mass of ca. 38 kDa was identified by SDS-PAGE. Hydropathy profiles indicated that there are two variable domains in the OmpH. To express the ompH in E. coli, the gene was manipulated in various ways. Expression of the truncated as well as full-length forms of the recombinant OmpH was fatal to the host E. coli BL21 (DE3). However, the truncated OmpH fused with GST was consecutively expressed in E. coli DH5$\alpha$. A large quantity of the fused polypeptide was purified through GST-affinity chromatography.

Isolation of a Bacterium with Potent Antibacterial Activity against Swine Atrophic Rhinitis Bacteria and Antibacterial Activities (돼지 위축성 비염균에 대한 항균성을 나타내는 세균의 분리 및 항균활성)

  • 이종수;강석휘;서승보;김재호
    • KSBB Journal
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    • v.17 no.3
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    • pp.317-320
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    • 2002
  • A bacterium(Y-5) which has potent antibacterial activity against swine atrophic rhinitis bacteria (Bordetella bronchiseptica, Pasteurella multocida) was isolated from soil and identified as a strain of Bacillus sp. Y-5 upon investigation of the morphological and physiological characteristics. The culture broth obtained from incubation of the Y-5 strain at $30^{\circ}C$ for 21 h in tryptose-bouillon agar medium (pH 6.0) showed active antibacterial activity against Bordetella bronchiseptica and the culture broth that of $30^{\circ}C$, pH 6.5, 18 h showed active antibacterial activity against Pasteurella multocida.

Comparison of local reaction at injection site following intramuscular administration with three commercial atrophic rhinitis vaccines in pigs

  • Kim, Myung-Hyee;Kwon, Taeyong;Yoo, Sung J.;Seo, Sang won;Park, Jun Woo;Lyoo, Young S.
    • Korean Journal of Veterinary Service
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    • v.41 no.4
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    • pp.251-255
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    • 2018
  • Bordetella bronchiseptica and Pasteurella multocida are two main pathogens responsible for atrophic rhinitis (AR), which causes considerable economic losses in swine industry worldwide. Commercial vaccine has been widely used to prevent the damage from AR in Korea. Adverse effects of vaccination at the injection site have been reported, which results in the numerous complaint from farms. However, data on about local reaction at the injection site remains limited. In this study, we compared the local adverse effects of three commercial vaccines following intramuscular injection. The results showed that no gross lesion was founded at the injection sites of all three vaccines. In histopathologic examination, a various level of lesions was identified. Especially, the local reaction of vaccine including saponin as an adjuvant showed the lowest level of histopathological lesions, when compared to those of oil-based and vitamin E-based vaccines. Therefore, this study would provide the information about the extent of local reaction at the injection site and help the farmer to select AR vaccine in order to avoid adverse reaction due to vaccination.

Control of Atrophic Rhinitis in Swine (돼지전염성위축성비염 예방)

  • Kang Byong-Kyu
    • Journal of the korean veterinary medical association
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    • v.18 no.3
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    • pp.10-19
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    • 1982
  • The present conditions of at rophic rhinitis of swine or Bordetellosis of swine and recent research ,progress have been introduced. Phase variations are emphasized to select a strain as an antigen for serolo diagnosis and an effective protective substance

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Survey on Incidence of Infectious Atrophic Rhinitis of Swine and Its Elimination by Chemotherapeutic Theraphy (돈의 전염성위축성비염(AR)의 발생역학적조사와 약제치료시험)

  • Rhee S.H.;Wee S.H.;Kim S.J.;Kang B.K.
    • Journal of the korean veterinary medical association
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    • v.15 no.6
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    • pp.323-330
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    • 1979
  • Epidemiological and etiological studies were carried out on infectious atrophic. rhinitis of swine (AR) at Suncheon district in Jeonnam during from July to October in 1978, and trials for the elimination of Bordetella bronchiseptica (B. bronchiseptica) fr

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