• Journal of Biomedical Engineering Research
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• v.36 no.4
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• pp.135-142
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• 2015

Outflow cannulation site of left ventricular assist device(LVAD) chosen by considering anatomical structure of thoracic cavity and vascular system. Though outflow cannulation site influences blood perfusion at each branch, there is no standard rule or quantitative data. In this study, we computed the amount of blood perfusion at each arterial branch numerically according to outflow cannulation sites(ascending aorta, aortic arch, descending aorta). We generated computational meshes to the three-dimensionally reconstructed arterial system. Clinically measured arterial pressure were used for inlet boundary condition, porous media were applied to mimic blood flow resistance. Blood perfusion through left common carotid artery was 2.5 times higher than other cases, and that through right common carotid artery was 1.1 times higher than other branches. Although this is simulation study, will be useful reference data for the clinical study of LVAD which considers blood perfusion efficiency.

• Journal of Chest Surgery
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• v.45 no.2
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• pp.116-119
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• 2012

A 61-year-old female patient was diagnosed with dilated cardiomyopathy with severe left ventricle dysfunction. Two days after admission, continuous renal replacement therapy was performed due to oliguria and lactic acidosis. On the fifth day, an intra-aortic balloon pump was inserted due to low cardiac output syndrome. Beginning 4 days after admission, she was supported for 15 days thereafter with an extracorporeal left ventricular assist device (LVAD) because of heart failure with multi-organ failure. A heart transplant was performed while the patient was stabilized with the LVAD. She developed several complications after the surgery, such as cytomegalovirus pneumonia, pulmonary tuberculosis, wound dehiscence, and H1N1 infection. On postoperative day 19, she was discharged from the hospital with close follow-up and treatment for infection. She received follow-up care for 10 months without any immune rejection reaction.

• Transactions of the Korean Society of Automotive Engineers
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• v.21 no.5
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• pp.54-58
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• 2013

In recent days, vehicles have become equipped with electric systems that assist and help drivers driving safe by reducing possible accidents. LDWS(Lane Departure Warning System) and LKAS(Lane Keeping Assistant System) are involved in assist systems, especially for lateral motion of vehicles. Sudden and inattentive lateral motion of vehicles due to drivers' fatigue, illness, inattention, and drowsiness are major causes of accidents in highway. LDWS and LKAS provide drivers with warnings or assisting power to reduce any possibilities of accidents. In order to prevent or minimize the possibilities of accidents, lateral motion control of vehicles has been introduced in this research. DGPS/RTK(Differential Global Positioning System/Real Time Kinematics) and GIS(Geographic Information System) have been used to obtain the current position of vehicles and decide when activate controlling lateral motion of vehicles. The presented lateral motion control has been validated with actual vehicle tests.

• Korean Management Science Review
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• v.23 no.1
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• pp.1-19
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• 2006

This study investigates the critical success factors for the promotion of IT industry in region and suggests some directions for operations strategy of them. This study based on the critical success factors, and we suggest followings : (1) start-ups support, (2) technology support, (3) management support, (4) law/institutional support. We suggested the strategy which based on critical success factors for successful operations of IT industry. This strategy suggested by AHP(Analytic Hierarchy Process) results and was evaluated by the three groups(IT firms, local government official worker, professor) which have an influence on IT policy. We suggested the priority of policy by AHP technique for successful development of IT industry. As a results, centralization of supporting facilities was perceived as the most important policy by three groups(IT firms, local government official worker, professor). This research contributes to assist planners and policy-makers in supporting IT industry by providing useful information about the suggested strategy, and by suggesting the effective means to assist the IT industry. Also, results of our research will be suggested as a priority of developing policy to assist successful IT industry.

• Journal of Biomedical Engineering Research
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• v.25 no.1
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• pp.65-70
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• 2004

In this paper, we described 23 cases of animal experiment with our pneumatic ventricular assist device and new durability-improvement method. The blood pump consists of blood housing, and back plate made by the injection molding of isoplast, and the diaphragm fabricated by dipping of polyurethane solution onto the aluminum mold. Its volume was 75 $m\ell$ and in-vitro test showed that maximum output was 4.5 $\ell$/min at the 100 mmHg. The adult female sheep with weight of 50 ＋ 10 kg were employed for tile in-vivo experiments and the mean blood flow was sustained at 3.0 1/min. 4 animals survived more than 15 days and the longest survival time was 28 days. In the prior 10 cases, the major causes of death were the tearing of diaphragm at the diaphragm to blood housing junction. By the new mesh and alumina ball milling methods, the durability was enhanced, and its qualitative and quantitative improvement was proved via the in-vivo and in-vitro methods. Animal experiments demonstrated that all the physiologic parameters a ere maintained within the permissible ranges and no thrombus formation was observed through the visual and blood test. The in-vivo experiments demonstrated our pneumatic ventricular assist device to he one month's bridge to transplantation device.

• Journal of Drive and Control
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• v.11 no.4
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• pp.61-67
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• 2014

When a manual transmission equipped car stops on an incline where the nose of the car is higher than the rear, hill-start control or hill-holder could prevent the vehicle from rolling backward as the car moves forward. The easy-hill assist valve consists of a check valve and a needle type ON/OFF solenoid valve connected in parallel; it is a hydraulic actuator that can maintain brake pressure using an electrical signal from the ECU. As the EHA valve is a safety-related component of the brake system, high reliability as well as superior dynamic performance is required for it to be applied in commercial vehicles. This paper presents the design of the EHA valve as a piece of equipment that can simulate the brake actuation pressure with a pressurizing piston. Following specific test standards, the experimental results validate the implemented functions of the test equipment, proving the test stand to be effective for the performance and endurance of the EHA valve.

• Journal of Biomedical Engineering Research
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• v.14 no.2
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• pp.163-167
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• 1993

We developed a ventricular assist device(VAD) to be used as a bridge to heart transplantation or a circulatory assist device for patients with end-stage heart disease or poor myocardial function after cardiac surgery. It is a pneumatic and diaphragm-type VAD and its stroke volume is 90 cc. The upper housing and diaphragm is made of a segmented polyurethane and the lower back plate is made of a polycarbonate. Two Carbomedics$^R$ mechanical valves are used as inlet and outlet valves. It was tested in vitro and the cardiac output of the VAD was 7 L/min at a heart rate of 70 bpm. The line pressure from a pressure transducer inserted in the pneumatic line was recorded and compared with the ideal pressure tracing.

• Advances in biomechanics and applications
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• v.1 no.1
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• pp.23-40
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• 2014

This paper examines the blood chamber of a left ventricular assist device (LVAD) under static loading conditions and standard operating temperatures. The LVAD's walls are made of a temperature-sensitive polymer (ChronoFlex C 55D) and are covered with a titanium nitride (TiN) nano-coating (deposited by laser ablation) to improve their haemocompatibility. A loss of cohesion may be observed near the coating-substrate boundary. Therefore, a micro-scale stress-strain analysis of the multilayered blood chamber was conducted with FE (finite element) code. The multi-scale model included a macro-model of the LVAD's blood chamber and a micro-model of the TiN coating. The theories of non-linear elasticity and elasto-plasticity were applied. The formulated problems were solved with a finite element method. The micro-scale problem was solved for a representative volume element (RVE). This micro-model accounted for the residual stress, a material model of the TiN coating, the stress results under loading pressures, the thickness of the TiN coating and the wave parameters of the TiN surface. The numerical results (displacements and strains) were experimentally validated using digital image correlation (DIC) during static blood pressure deformations. The maximum strain and stress were determined at static pressure steps in a macro-scale FE simulation. The strain and stress were also computed at the same loading conditions in a micro-scale FE simulation.

• Journal of Korean Clinical Health Science
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• v.6 no.2
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• pp.1115-1125
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• 2018

purpose : The purpose of the study is to investigate opinion on the legalization of the actual work of clinical dental hygienists. Methods : A self-reported questionnaire was completed by 171 dental hygienists in Busan and Gyeongnam from December 1, 2017 to January 31, 2018. Structured questionnaires were uesd for analysis. The collected data was analyzed using IBM SPSS. Statistic 20.0. Results : The first, assist of dental treatment, Second, dental health care education and consulting duties, and third priority preventive duties were found to be the most important duties in the dental office. Currently, it was investigated perform in a lot of workplace. Preventive treatment tasks include scaling, teeth polishing, applying fluoride and assist of dental treatment include preparation for medical care, preparation for implant surgery, preparation for oral surgery, implant surgery assistant and patient care training, and preparation for periodontal surgery. Conclusion : As a result, the dental hygienist performing a lot of dental assist tasks, oral health education counseling and preventive duties. Nonetheless, clinical dental hygienists are outlaws due to the disparity between practical and legal duties. Therefore, it is urgent to legislate actual duties of dental hygienist so that experts can fully exercise the competency of the public in promoting dental health. Relevant governments and related organizations should take reasonable measures to solve this problem.

• Journal of Chest Surgery
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• v.57 no.3
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• pp.312-314
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• 2024

A 3-year-old boy with Glenn physiology exhibited refractory heart failure with reduced ejection fraction. To improve the patient's oxygen saturation, he underwent ventricular assist device (VAD) implantation with concomitant Fontan completion. The extracardiac conduit Fontan operation was performed with a 4-mm fenestration. For VAD implantation, Berlin Heart cannulas were positioned at the left ventricular apex and the neo-aorta. Following weaning from cardiopulmonary bypass, a temporary continuous-flow VAD, equipped with an oxygenator, was utilized for support. After a stabilization period of 1 week, the continuous-flow VAD was replaced with a durable pulsatile-flow device. Following 3 months of support, the patient underwent transplantation without complications. The completion of the Fontan procedure at the time of VAD implantation, along with the use of a temporary continuous-flow device with an oxygenator, may aid in stabilizing postoperative hemodynamics. This approach could contribute to a safe transition to a durable pulsatile VAD in patients with Glenn physiology.