• Biomolecules & Therapeutics
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• v.3 no.3
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• pp.242-244
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• 1995

In vitro cell culture system has been proposed as a promising alternative model to in vivo skin irritation test. These studies were performed to screen the cytotoxicity effects of surfactants using normal human skin fibroblasts. Cell membrane integrity assessed by the leakage of lactate dehydrogenase (LDH) and mitochondrial integrity by MTT [3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyl tetrazolium bromides reduction test were affected in a dose dependent manner. The irritation potential of surfactants to human skin patch test, and the changes of capillary permeability by rabbit intradermal safety test were assessed as in vivo methods. Our results suggest that LDH leakage assay and MTT reduction test using cultured human fibroblasts could be predictive for the irritancy of various surfactants in human, and LDH assay is superior correlated with in vivo test (r=0.886) to MTT test with in vivotest (r=0.757).

• The Journal of Korean Physical Therapy
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• v.21 no.2
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• pp.55-63
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• 2009

Purpose: This study evaluated of quality of life (QOL) and physical therapy satisfaction (PTS) in caregivers of cerebral palsy children. Methods: Eighty six caregivers in Gwang-ju were examined. The caregivers' QOL was assessed through self-reports using the WHO Quality of Life-BREF (WHOQOL-BREF), and the data was analyzed separately for each of its 5 domains. Physical therapy satisfaction was assessed using a self-reported questionnaire and the data was analyzed separately for the 2 domains. The results were processed by the mean and standard deviation and then verified by ANOVA and a t-test to determine the significant differences in the QOL and PTS. The factors affecting the QOL were processed by logistic regression. Results: Life environment domain of the QOL across the caregivers factors showed a statistically significant difference in age at natal, monthly income and education. The birth order in the cerebral palsy child factor showed a significant difference in the general, physical and emotional domain of the QOL. The PTS showed a significant difference in the delivery of therapy domain and in the birth order and walking condition of the environment domain. Caregivers education was found to be associated independently with the life environment domain of QOL. Conclusion: Because the QOL of caregivers is an important treatment goal for children with cerebral palsy, early family intervention should be considered.

• The Korean Journal of Rehabilitation Nursing
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• v.20 no.1
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• pp.12-21
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• 2017

Purpose: This study attempts to examine the effects of a horticultural program on activities of daily living (ADL) and depression among older patients with mild dementia. Methods: This study adopted a quasi-experimental design-based nonequivalent control group pretest and posttest design, enrolling 30 older patients with mild dementia. The Korean Form of Geriatric Depression Scale was utilized, while the data was collected from the experimental group for 60 minutes, twice weekly for 6 weeks in 12 sessions. ADL and depression were assessed for both the experimental and the control group. Overall functions were assessed only for the experimental group. Results: The experimental group showed improvement in physical function, cognitive function, as well as psychological, emotional function and social function following each session (p<.001). The horticulture program was effective in both ADL ($Z^2=5.65$, p<.001) and depression (t=-5.24, p<.001). Conclusion: In this study, the horticultural therapy based on the Cox's interaction model had positive effects for older patients with mild dementia. Therefore, horticultural therapy may be commendably applied to older patients with mild dementia as a nursing intervention.

• Nuclear Engineering and Technology
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• v.47 no.3
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• pp.362-379
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• 2015

In this study, Nuclear Power Plant (NPP) construction schedule delay risk assessment methodology is developed and the construction delay risk is assessed for turnkey international NPP projects. Three levels of delay factors were selected through literature review and discussions with nuclear industry experts. A questionnaire survey was conducted on the basis of an analytic hierarchy process (AHP) and Relative Importance Index (RII) methods and the schedule delay risk is assessed qualitatively and quantitatively by severity and frequency of occurrence of delay factors. This study assigns four main delay factors to the first level: main contractor, utility, regulatory authority, and financial and country factor. The second and the third levels are designed with 12 sub-factors and 32 sub-sub-factors, respectively. This study finds the top five most important sub-sub-factors, which are as follows: policy changes, political instability and public intervention; uncompromising regulatory criteria and licensing documents conflicting with existing regulations; robust design document review procedures; redesign due to errors in design and design changes; and worldwide shortage of qualified and experienced nuclear specific equipment manufacturers. The proposed combined AHP-RII methodology is capable of assessing delay risk effectively and efficiently. Decision makers can apply risk informed decision making to avoid unexpected construction delays of NPPs.

• PNF and Movement
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• v.14 no.2
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• pp.139-147
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• 2016

Purpose: This study examined whether a single application of a lumbar flexion muscle energy technique (MET) could significantly influence pain, functional status, and range of motion in chronic back pain patients with restricted active trunk flexion. Methods: Twenty volunteers were randomly assigned to either a control group or an experimental group. Ten subjects in the control group received no treatment. Ten subjects in the experimental group received five sessions with the muscle energy technique, five times per week for two weeks. Outcomes were measured before and after two weeks of treatment in both groups. Pain intensity was assessed using a visual analogue scale (VAS). Range of motion was measured using the sit-and-reach test (SRT). Functional disability levels were assessed using the Korean version of the Oswestry Disability Index (KODI). Results: The experimental group showed a significant difference in VAS, KODI, and SRT between pre- and post-treatment (p < .05), while the control group showed no significant changes. The changes in VAS, ODI, and SRT were statistically significant between the groups pre- and post-treatment (p < .05). Conclusion: This muscle energy technique is clinically effective for chronic low back pain patients.

• PNF and Movement
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• v.18 no.2
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• pp.159-172
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• 2020

Purpose: The study sought to determine whether goal achievement, performance, satisfaction, activities of daily living, and gross motor function in children with spastic cerebral palsy are positive affected by goal-oriented functional task training. Methods: In a single case study, two 7-year-old girls diagnosed with spastic cerebral palsy were given functional task training based on individualized goals for 24 60-minute sessions over a period of 6 months. The individualized goals reflected the needs of both children and parents. The Canadian occupational performance measure (COPM) and the goal attainment scale (GAS) were used to measure goal performance and satisfaction before and after intervention. Independence of activities of daily living before and after intervention were assessed using the functional independence measure for children (Wee-FIM). And change of gross motor function were assessed using gross motor function measure (GMFM). Results: Clinically significant changes were observed in COPM and GAS, as well as positive changes in independence of gross motor function and activities of daily living. Conclusion: The findings indicate that goal-oriented functional task training addresses the needs of children with spastic cerebral palsy, which increases treatment satisfaction and has a positive effect on independent activities and participation in daily life.

• PNF and Movement
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• v.8 no.1
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• pp.67-77
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• 2010

Purpose : The purpose of this study was to investigate the usefulness of clinical balance tests through the correlation of balance evaluation using by forceplate in elderly. Methods : Thirty nine healthy elderly subjects (14 males, 25 females) participated in the study. The subjects were evaluated with clinical balance tests [(Berg balance scale (BBS), Functional reach test (FRT), Tinetti's performance oriented mobility assessment (POMA), and one leg standing (OLS)]. Static balance evaluation was assessed by using forceplate. Center of pressure (COP) parameters were obtained using it as total path distance, total sway area, X mean frequency and Y mean frequency for 20 seconds in the following conditions: (1) comfortable standing with eyes opened and closed, (2) uncomfortable standing with eyes opened and closed. After static balance evaluation tested, dynamic balance evaluation was assessed. COP parameters were error distance and area during sine curve trace. COP parameters were movement time, error distance, and maintained time in the circle during COP movement task. Results : Clinical balance tests showed statistically significant correlation between static and dynamic balance evaluations. Among the clinical balance tests, the BBS, POMA, and OLS showed significant correlation with to assess the balance ability of elderly in clinical setting both evaluations. Conclusion : Clinical balance tests can be recommended in clinical setting because of low costs and simplicity.

• The Korean Journal of Emergency Medical Services
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• v.23 no.3
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• pp.41-51
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• 2019

Purpose: This dissertation is a descriptive research study analyzing the accuracy and reliability of the cardiopulmonary resuscitation (CPR) application developed in Korea. Methods: Two faculty members from the emergency medical services department and the emergency medicine department searched applications from July 1 to July 10, 2019 and selected a total of 13 applications. Twelve questions were assessed for information accuracy and three were assessed for reliability. In accordance with application types, the number and mean ± standard deviation were analyzed. The t-test was used to compare the accuracy of CPR information in accordance with information sources. Results: The results revealed the following errors: 7 cases (53.8%) identified the chest center lining from the nipple center-line as the chest pressure point; 5 cases (38.5%) did not provide information on the depth of 6 cm that should not be exceeded; and 4 cases (30.8%) did not provide advise to check respiration. When the CPR information sources were included, the information accuracy score was high; a significant difference was observed (p=.035). Conclusion: In the case of applications providing medical information regarding CPR, it is necessary to provide at least authoritarian, sources of information, and author transparency as well as continuous effort and attention.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.22 no.1
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• pp.51-55
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• 2000

Purpose : The purpose of this study is to setup a standard treatment protocol in surgical correction of skeletal malocclusion with Angle Class III patients. We asessed the soft tissue changes according to skeletal changes of patients who have undergone orthognathic surgery with bilateral split sagittal ramus osteotomy (BSSRO) and advancing genioplasty. Materials & Methods : The soft tissue change of 9 skeletal Class III patients was assessed after BSSRO and advancing genioplasty. The patient group was skeletal Class III who was surgically treated by BSSRO & advancing genioplasty. The average follow up period is 13 months with the range of 6 and 30 months. All patients have undergone preoperative and postoperative orthodontic treatment. The assessment was devided into two groups. One was antero-posterior relationship and the other was vertical relationship of dimensional changes of soft tissue after orthognathic surgery. Results : In antero-posterior dimensional changes after surgery, the percentage of soft tissue change in comparison to hard tissue was 89%. Vertical ratio after surgery, 86% soft tissue changes were assessed.

• Journal of Sasang Constitutional Medicine
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• v.30 no.3
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• pp.104-115
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• 2018

Introduction The aim of this study was to report significant improvement of Dyshidrosis(Pompholyx) patient who was diagnosed with 'Soyangin chest-bind symptomatic pattern' based on Sasang Constitutonal medicine. Methods The patient was treated with herbal medicine, acupuncture, as well as western medicine. To evaluate the results of this treatment, the patient assessed discomfort of dyshidrosis by using Numeral Rating Scale(NRS), percentage(%) and we assessed severity of dyshidrosis by using Dyshidrotic Eczema Area and Severity Index(DASI). Results At the time of admission, the degree of discomfort in the dyshidrosis symptoms was NRS 8 and the severity of dyshidrosis was DASI 16(moderate). After the treatment, her symptoms was improved(NRS 0, DASI 0). Sleep, digestion and defecation condition were also improved. Discussion The patient who had frequent recurrence showed a significant improvement of dyshidrosis and accessory symptoms without any side effects, who was treated with Hyeongbangdojeok-san, acupuncture and western medicine.